FI60012C - Foerfarande foer framstaellning av terapeutiskt aktiva 2-(7-klor-1,8-naftyridin-2-yl)-3-(karbamoyloxi)isoindolin-1-oner - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva 2-(7-klor-1,8-naftyridin-2-yl)-3-(karbamoyloxi)isoindolin-1-oner Download PDF

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Publication number
FI60012C
FI60012C FI760937A FI760937A FI60012C FI 60012 C FI60012 C FI 60012C FI 760937 A FI760937 A FI 760937A FI 760937 A FI760937 A FI 760937A FI 60012 C FI60012 C FI 60012C
Authority
FI
Finland
Prior art keywords
chloro
group
carbon atoms
naphthyridin
isoindolin
Prior art date
Application number
FI760937A
Other languages
English (en)
Finnish (fi)
Other versions
FI60012B (fi
FI760937A (da
Inventor
Claude Cotrel
Cornel Crisan
Claude Jeanmart
Andre Leger
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7510756A external-priority patent/FR2321290A1/fr
Priority claimed from FR7603774A external-priority patent/FR2340731A1/fr
Priority claimed from FR7603773A external-priority patent/FR2340733A2/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of FI760937A publication Critical patent/FI760937A/fi
Priority to FI811276A priority Critical patent/FI63589C/fi
Publication of FI60012B publication Critical patent/FI60012B/fi
Application granted granted Critical
Publication of FI60012C publication Critical patent/FI60012C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/54—Preparation of carboxylic acid anhydrides
    • C07C51/56—Preparation of carboxylic acid anhydrides from organic acids, their salts, their esters or their halides, e.g. by carboxylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI760937A 1975-04-07 1976-04-07 Foerfarande foer framstaellning av terapeutiskt aktiva 2-(7-klor-1,8-naftyridin-2-yl)-3-(karbamoyloxi)isoindolin-1-oner FI60012C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI811276A FI63589C (fi) 1976-02-11 1981-04-23 Foerfarande foer framstaellning av terapeutiskt aktiva 6-(7-klor-1,8-naftyridin-2-yl)-5-karbamoyloxi-7-oxo-6,7-dihydro-5h-pyrrolo(3,4-b)pyraziner

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FR7510756A FR2321290A1 (fr) 1975-04-07 1975-04-07 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7510756 1975-04-07
FR7603774A FR2340731A1 (fr) 1976-02-11 1976-02-11 Nouveaux composes heterocycliques, leur preparation et les compositions qui les contiennent
FR7603773A FR2340733A2 (fr) 1976-02-11 1976-02-11 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7603774 1976-02-11
FR7603773 1976-02-11

Publications (3)

Publication Number Publication Date
FI760937A FI760937A (da) 1976-10-08
FI60012B FI60012B (fi) 1981-07-31
FI60012C true FI60012C (fi) 1981-11-10

Family

ID=27250439

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760937A FI60012C (fi) 1975-04-07 1976-04-07 Foerfarande foer framstaellning av terapeutiskt aktiva 2-(7-klor-1,8-naftyridin-2-yl)-3-(karbamoyloxi)isoindolin-1-oner

Country Status (29)

Country Link
US (1) US4086348A (da)
JP (1) JPS51122094A (da)
AR (3) AR214286A1 (da)
AT (1) AT348524B (da)
CA (1) CA1072957A (da)
CH (2) CH613453A5 (da)
CS (3) CS186734B2 (da)
CY (1) CY1085A (da)
DD (1) DD123605A5 (da)
DE (1) DE2615067A1 (da)
DK (1) DK162976A (da)
ES (2) ES446762A1 (da)
FI (1) FI60012C (da)
GB (1) GB1483996A (da)
HK (1) HK54580A (da)
HU (1) HU176315B (da)
IE (1) IE42973B1 (da)
IL (1) IL49344A (da)
LU (1) LU74703A1 (da)
MX (1) MX3138E (da)
NL (1) NL7603307A (da)
NO (1) NO144019C (da)
OA (1) OA05287A (da)
PH (1) PH14015A (da)
PL (3) PL100987B1 (da)
PT (1) PT64976B (da)
SE (2) SE7604044L (da)
SU (3) SU648102A3 (da)
YU (3) YU86976A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1265803A (fr) * 1985-07-11 1990-02-13 Claude Cotrel Amides substitues, leur preparation et les medicaments qui les contiennent
DE10042093A1 (de) * 2000-08-26 2002-03-07 Dresden Arzneimittel Antikonvulsiv wirkende 6,7-Dihydro-pyrrolo[3,4-d]pyridin-5-one und Verfahren zu deren Darstellung
ZA200503697B (en) 2002-11-26 2006-10-25 Maruishi Pharma Isoindoline derivatives
WO2007080430A1 (en) * 2006-01-16 2007-07-19 Generics [Uk] Limited Novel process
US9682967B2 (en) 2013-01-28 2017-06-20 H. Lundbeck A/S N-substituted-5-substituted phthalamic acids as sortilin inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.

Also Published As

Publication number Publication date
YU86976A (en) 1983-02-28
PL100988B1 (pl) 1978-11-30
FI60012B (fi) 1981-07-31
GB1483996A (en) 1977-08-24
CH613453A5 (da) 1979-09-28
NO144019B (no) 1981-02-23
FI760937A (da) 1976-10-08
LU74703A1 (da) 1977-02-02
PL100184B1 (pl) 1978-09-30
SE421793B (sv) 1982-02-01
NO761168L (da) 1976-10-08
NO144019C (no) 1981-06-03
IE42973B1 (en) 1980-11-19
CS186734B2 (en) 1978-12-29
HU176315B (en) 1981-01-28
SU638258A3 (ru) 1978-12-15
SE7604044L (sv) 1976-10-08
CY1085A (en) 1980-12-27
SU648102A3 (ru) 1979-02-15
CS186748B2 (en) 1978-12-29
CA1072957A (fr) 1980-03-04
AR214286A1 (es) 1979-05-31
AR214055A1 (es) 1979-04-30
IL49344A0 (en) 1976-06-30
IE42973L (en) 1976-10-07
PT64976B (fr) 1977-09-07
YU130582A (en) 1983-02-28
YU130482A (en) 1983-02-28
JPS62149B2 (da) 1987-01-06
AU1267476A (en) 1977-10-13
HK54580A (en) 1980-10-03
AT348524B (de) 1979-02-26
AR213739A1 (es) 1979-03-15
MX3138E (es) 1980-05-06
DK162976A (da) 1976-10-08
PH14015A (en) 1980-12-08
PL100987B1 (pl) 1978-11-30
OA05287A (fr) 1981-02-28
NL7603307A (nl) 1976-10-11
PT64976A (fr) 1976-05-01
IL49344A (en) 1979-05-31
US4086348A (en) 1978-04-25
DD123605A5 (da) 1977-01-05
SU637082A3 (ru) 1978-12-05
JPS51122094A (en) 1976-10-25
CH614209A5 (en) 1979-11-15
CS186747B2 (en) 1978-12-29
ES446762A1 (es) 1977-06-01
ES448847A1 (es) 1977-10-01
DE2615067A1 (de) 1976-10-28
ATA249776A (de) 1978-07-15

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MM Patent lapsed

Owner name: RHONE- POULENC INDUSTRIES