FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
ES2231819T3
(es)
*
|
1995-06-07 |
2005-05-16 |
Inex Pharmaceuticals Corp |
Particulas de lipido-acido nucleico preparadas a traves de un intermedio complejo de lipido-acido nucleico hidrofobo y uso para transferir genes.
|
FR2739292B1
(fr)
*
|
1995-09-28 |
1997-10-31 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations
|
GB2324534B
(en)
*
|
1996-01-06 |
2000-05-10 |
Danbiosyst Uk |
Composition for delivery of nucleic acid to a cell
|
JP2001503041A
(ja)
*
|
1996-10-23 |
2001-03-06 |
エスケーダヴリュ トロストベルグ アクチエンゲゼルシャフト |
生物活性ポリマーナノ粒子―核酸接合体の製造方法
|
DK0956001T3
(da)
*
|
1996-11-12 |
2012-10-22 |
Univ California |
Fremstilling af stabile formuleringer af lipid-nukleinsyre-komplekser til virksom in-vivo indgivelse
|
US6884430B1
(en)
*
|
1997-02-10 |
2005-04-26 |
Aventis Pharma S.A. |
Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
|
WO1998040510A1
(en)
*
|
1997-03-11 |
1998-09-17 |
Regents Of The University Of Minnesota |
Dna-based transposon system for the introduction of nucleic acid into dna of a cell
|
US5912225A
(en)
|
1997-04-14 |
1999-06-15 |
Johns Hopkins Univ. School Of Medicine |
Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same
|
US6524613B1
(en)
|
1997-04-30 |
2003-02-25 |
Regents Of The University Of Minnesota |
Hepatocellular chimeraplasty
|
DE19726186A1
(de)
*
|
1997-06-20 |
1998-12-24 |
Boehringer Ingelheim Int |
Komplexe für den Transport von Nukleinsäure in höhere eukaryotische Zellen
|
US20020022034A1
(en)
*
|
1997-09-15 |
2002-02-21 |
Julianna Lisziewicz |
Therapeutic DNA vaccination
|
ATE347911T1
(de)
|
1997-09-15 |
2007-01-15 |
Genetic Immunity Llc |
Zusammensetzungen für die zufuhr von genen an antigen-präsentierende zellen der haut
|
DE19743135A1
(de)
|
1997-09-30 |
1999-04-01 |
Hoechst Marion Roussel De Gmbh |
Biologisch verträgliche niedermolekular Polyethylenimine
|
WO1999065531A1
(en)
*
|
1998-06-18 |
1999-12-23 |
Johns Hopkins University School Of Medicine |
Polymers for delivery of nucleic acids
|
US6916490B1
(en)
|
1998-07-23 |
2005-07-12 |
UAB Research Center |
Controlled release of bioactive substances
|
EP1044679B1
(en)
*
|
1998-11-02 |
2012-12-26 |
Terumo Kabushiki Kaisha |
Stable Liposomes for Targeted Drug Delivery
|
US7160682B2
(en)
*
|
1998-11-13 |
2007-01-09 |
Regents Of The University Of Minnesota |
Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
|
IL145592A0
(en)
*
|
1999-04-02 |
2002-06-30 |
Res Dev Foundation |
Polyethyleneimine: dna formulations for aerosol delivery
|
US6770740B1
(en)
|
1999-07-13 |
2004-08-03 |
The Regents Of The University Of Michigan |
Crosslinked DNA condensate compositions and gene delivery methods
|
FR2797402B1
(fr)
|
1999-07-15 |
2004-03-12 |
Biomerieux Stelhys |
Utilisation d'un polypeptide pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique ou autoimmune
|
DE19960206A1
(de)
*
|
1999-12-14 |
2001-07-19 |
Frank Czubayko |
Komplexierung von RNS mit Polyethyleniminen zur deren Stabilisierung und zellulären Einschleusung
|
AU782912B2
(en)
|
1999-12-28 |
2005-09-08 |
Association Francaise Contre Les Myopathies |
Use of lithium (Li+) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy
|
AU3366901A
(en)
*
|
1999-12-30 |
2001-07-16 |
Novartis Ag |
Novel colloid synthetic vectors for gene therapy
|
FR2805271B1
(fr)
*
|
2000-02-18 |
2002-04-26 |
Aventis Pharma Sa |
Procede de preparation de polyalkylenimines fonctionnalises, compositions les contenant et leurs utilisations
|
FR2813605B1
(fr)
*
|
2000-09-05 |
2002-10-18 |
Aventis Pharma Sa |
Composes acidosensibles, leur preparation et utilisations
|
WO2002020510A1
(fr)
*
|
2000-09-05 |
2002-03-14 |
Gencell S.A. |
Composes acidosensibles, leur preparation et utilisations
|
FR2814370B1
(fr)
*
|
2000-09-22 |
2004-08-20 |
Centre Nat Rech Scient |
Utilisation d'un complexe acide nucleique/pei pour le ciblage de cellules souches du cerveau
|
EP1326645A1
(de)
*
|
2000-10-09 |
2003-07-16 |
Bayer Aktiengesellschaft |
Komplexe zur einführung von nukleinsäuren in zellen
|
DE10145134A1
(de)
*
|
2000-10-09 |
2002-05-16 |
Bayer Ag |
Komplexe zur Einführung von Nukleinsäuren in Zellen
|
US20020091242A1
(en)
*
|
2000-10-11 |
2002-07-11 |
Michel Bessodes |
Acid-sensitive compounds, their preparation and uses
|
CA2437555A1
(en)
*
|
2001-02-01 |
2002-08-08 |
Yiyu Zou |
Stabilised polymeric aerosols for pulmonary gene delivery
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
WO2002100435A1
(en)
*
|
2001-06-11 |
2002-12-19 |
Centre Hospitalier Universitaire De Montreal |
Compositions and methods for enhancing nucleic acid transfer into cells
|
DE60234375D1
(de)
|
2001-09-14 |
2009-12-24 |
Cytos Biotechnology Ag |
VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
|
AU2002348163A1
(en)
*
|
2001-11-02 |
2003-05-19 |
Intradigm Corporation |
Therapeutic methods for nucleic acid delivery vehicles
|
JP4202928B2
(ja)
|
2002-01-17 |
2008-12-24 |
アルファ ラバル コーポレート アクティエボラーグ |
一体式熱交換器を有する浸水式蒸発器
|
US8227432B2
(en)
*
|
2002-04-22 |
2012-07-24 |
Regents Of The University Of Minnesota |
Transposon system and methods of use
|
WO2003099225A2
(en)
|
2002-05-24 |
2003-12-04 |
Mirus Corporation |
Compositions for delivering nucleic acids to cells
|
DK1519714T3
(da)
|
2002-06-28 |
2011-01-31 |
Protiva Biotherapeutics Inc |
Fremgangsmåde og apparat til fremstilling af liposomer
|
KR101360955B1
(ko)
*
|
2002-09-13 |
2014-02-10 |
레플리코르 인코포레이티드 |
비서열 상보적 항바이러스 올리고뉴클레오티드
|
US20050196382A1
(en)
*
|
2002-09-13 |
2005-09-08 |
Replicor, Inc. |
Antiviral oligonucleotides targeting viral families
|
ES2784011T3
(es)
|
2002-10-16 |
2020-09-21 |
Streck Inc |
Procedimiento y dispositivo para recoger y preservar las células para su análisis
|
US7153905B2
(en)
*
|
2003-03-21 |
2006-12-26 |
The General Hospital Corporation |
Hyperbranched dendron and methods of synthesis and use thereof
|
NZ544637A
(en)
|
2003-07-16 |
2010-04-30 |
Protiva Biotherapeutics Inc |
Lipid encapsulated interfering RNA
|
EP1664316B1
(en)
|
2003-09-15 |
2012-08-29 |
Protiva Biotherapeutics Inc. |
Polyethyleneglycol-modified lipid compounds and uses thereof
|
US20060058255A1
(en)
*
|
2004-03-01 |
2006-03-16 |
Jianzhu Chen |
RNAi-based therapeutics for allergic rhinitis and asthma
|
EP1730286A4
(en)
*
|
2004-03-04 |
2007-09-05 |
Massachusetts Inst Technology |
ANTICANCER TREATMENT BASED ON DNA
|
US20060026699A1
(en)
*
|
2004-06-04 |
2006-02-02 |
Largaespada David A |
Methods and compositions for identification of genomic sequences
|
EP1781593B1
(en)
|
2004-06-07 |
2011-12-14 |
Protiva Biotherapeutics Inc. |
Cationic lipids and methods of use
|
ATE536418T1
(de)
|
2004-06-07 |
2011-12-15 |
Protiva Biotherapeutics Inc |
Lipidverkapselte interferenz-rna
|
CA2572439A1
(en)
|
2004-07-02 |
2006-01-12 |
Protiva Biotherapeutics, Inc. |
Immunostimulatory sirna molecules and uses therefor
|
CA2628300C
(en)
|
2005-11-02 |
2018-04-17 |
Protiva Biotherapeutics, Inc. |
Modified sirna molecules and uses thereof
|
US7915399B2
(en)
|
2006-06-09 |
2011-03-29 |
Protiva Biotherapeutics, Inc. |
Modified siRNA molecules and uses thereof
|
US20080312174A1
(en)
*
|
2007-06-05 |
2008-12-18 |
Nitto Denko Corporation |
Water soluble crosslinked polymers
|
AU2008298592A1
(en)
*
|
2007-09-14 |
2009-03-19 |
Nitto Denko Corporation |
Drug carriers
|
EP2047858A1
(en)
|
2007-10-10 |
2009-04-15 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Combination products for treating cancer
|
DE102007056488A1
(de)
|
2007-11-22 |
2009-07-23 |
Biontex Laboratories Gmbh |
Steigerung von Transfektionseffizienzen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
|
DE102008016275A1
(de)
|
2008-03-28 |
2009-11-19 |
Biontex Laboratories Gmbh |
Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
|
CN101918566A
(zh)
|
2007-11-22 |
2010-12-15 |
Biontex实验室有限公司 |
通过影响先天性免疫系统改进非病毒输送系统的转染结果
|
DE102008023913A1
(de)
|
2008-05-16 |
2009-11-19 |
Biontex Laboratories Gmbh |
Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Beeinflussung des angeborenen Immunsystems
|
GB0724253D0
(en)
|
2007-12-12 |
2008-01-30 |
Fermentas Uab |
Transfection reagent
|
WO2009082817A1
(en)
|
2007-12-27 |
2009-07-09 |
Protiva Biotherapeutics, Inc. |
Silencing of polo-like kinase expression using interfering rna
|
US7687027B2
(en)
*
|
2008-02-27 |
2010-03-30 |
Becton, Dickinson And Company |
Cleaning compositions, methods and materials for reducing nucleic acid contamination
|
FR2928373B1
(fr)
|
2008-03-05 |
2010-12-31 |
Centre Nat Rech Scient |
Polymere derive de la polyethylenimine lineaire pour le transfert de gene.
|
PL2279254T3
(pl)
|
2008-04-15 |
2017-11-30 |
Protiva Biotherapeutics Inc. |
Nowe preparaty lipidowe do dostarczania kwasów nukleinowych
|
EP2281041B1
(en)
|
2008-04-15 |
2014-07-02 |
Protiva Biotherapeutics Inc. |
Silencing of csn5 gene expression using interfering rna
|
US8637315B2
(en)
*
|
2008-05-15 |
2014-01-28 |
National Research Council Of Canada |
Process, vectors and engineered cell lines for enhanced large-scale transfection
|
EP2350043B9
(en)
|
2008-10-09 |
2014-08-20 |
TEKMIRA Pharmaceuticals Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
WO2010078194A1
(en)
*
|
2008-12-30 |
2010-07-08 |
Streck, Inc. |
Method for screening blood using a preservative that may be in a substantially solid state form
|
US11634747B2
(en)
*
|
2009-01-21 |
2023-04-25 |
Streck Llc |
Preservation of fetal nucleic acids in maternal plasma
|
DE102009006606A1
(de)
|
2009-01-29 |
2010-08-05 |
Philipps-Universität Marburg |
Nicht-virales Transfektionsmittel
|
ES2649572T3
(es)
|
2009-02-18 |
2018-01-12 |
Streck Inc. |
Conservación de ácidos nucleicos fuera de las células
|
EP2453911A1
(en)
|
2009-04-30 |
2012-05-23 |
Genetic Immunity Kft |
Immunogenic nanomedicine composition and preparation and uses thereof
|
US9018187B2
(en)
|
2009-07-01 |
2015-04-28 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
WO2011000106A1
(en)
|
2009-07-01 |
2011-01-06 |
Protiva Biotherapeutics, Inc. |
Improved cationic lipids and methods for the delivery of therapeutic agents
|
EP3252068A3
(en)
|
2009-10-12 |
2018-03-14 |
Larry J. Smith |
Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
|
GB0917792D0
(en)
*
|
2009-10-12 |
2009-11-25 |
Fermentas Uab |
Delivery agent
|
US9856456B2
(en)
|
2009-10-12 |
2018-01-02 |
Thermo Fisher Scientific Baltics Uab |
Delivery agent
|
WO2011057184A1
(en)
*
|
2009-11-09 |
2011-05-12 |
Streck, Inc. |
Stabilization of rna in and extracting from intact cells within a blood sample
|
WO2011117352A1
(en)
|
2010-03-24 |
2011-09-29 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Primate model from the family cercopithecidae infected by a hbv strain of human genotype
|
US8945927B2
(en)
|
2010-03-29 |
2015-02-03 |
Universite De Strasbourg |
Polymers for delivering molecules of interest
|
JP2013530187A
(ja)
|
2010-06-17 |
2013-07-25 |
ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
炎症性疾患を治療するための組成物及び方法。
|
CA2802463C
(en)
|
2010-06-22 |
2019-02-26 |
Dna Therapeutics |
Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
|
US9006417B2
(en)
|
2010-06-30 |
2015-04-14 |
Protiva Biotherapeutics, Inc. |
Non-liposomal systems for nucleic acid delivery
|
WO2012151391A2
(en)
|
2011-05-04 |
2012-11-08 |
Streck, Inc. |
Inactivated virus compositions and methods of preparing such compositions
|
WO2013040552A2
(en)
|
2011-09-16 |
2013-03-21 |
Georgia Health Sciences University |
Methods of promoting immune tolerance
|
US20150240238A1
(en)
|
2011-11-17 |
2015-08-27 |
The Regents Of The University Of California |
Therapeutic rna switches compositions and methods of use
|
PL2782997T3
(pl)
|
2011-11-24 |
2018-06-29 |
Genethon |
Skalowalny układ do wytwarzania wektora lentiwirusowego zgodny z przemysłowymi zastosowaniami farmaceutycznymi
|
US9035039B2
(en)
|
2011-12-22 |
2015-05-19 |
Protiva Biotherapeutics, Inc. |
Compositions and methods for silencing SMAD4
|
CA2873274C
(en)
*
|
2012-06-08 |
2021-06-01 |
Ethris Gmbh |
Pulmonary delivery of messenger rna
|
CN103059295B
(zh)
*
|
2012-09-26 |
2016-01-13 |
上海交通大学 |
疏水修饰的聚乙烯亚胺及其作为蛋白质载体的用途
|
EP4085930A1
(en)
|
2012-10-05 |
2022-11-09 |
BioNTech Delivery Technologies GmbH |
Hydroxylated polyamine derivatives as transfection reagents for rna
|
DK2903651T3
(da)
|
2012-10-08 |
2022-01-17 |
Biontech Delivery Tech Gmbh |
Carboxylerede polyaminderivater som transfektionsreagenser
|
DE102012111891A1
(de)
*
|
2012-12-06 |
2014-06-12 |
Eberhard Karls Universität Tübingen Medizinische Fakultät |
Verbesserung der Zielfindungskapazität von Stammzellen
|
WO2015013244A1
(en)
|
2013-07-24 |
2015-01-29 |
Streck, Inc. |
Compositions and methods for stabilizing circulating tumor cells
|
US20160296632A1
(en)
|
2013-11-13 |
2016-10-13 |
Aequus Biopharma, Inc. |
Engineered glycoproteins and uses thereof
|
EP3201338B1
(en)
|
2014-10-02 |
2021-11-03 |
Arbutus Biopharma Corporation |
Compositions and methods for silencing hepatitis b virus gene expression
|
EP3034539A1
(en)
|
2014-12-19 |
2016-06-22 |
Ethris GmbH |
Compositions for introducing nucleic acid into cells
|
US11168351B2
(en)
|
2015-03-05 |
2021-11-09 |
Streck, Inc. |
Stabilization of nucleic acids in urine
|
US20180154023A1
(en)
|
2015-05-05 |
2018-06-07 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Nucleic acid-cationic polymer compositions and methods of making and using the same
|
WO2016197132A1
(en)
|
2015-06-04 |
2016-12-08 |
Protiva Biotherapeutics Inc. |
Treating hepatitis b virus infection using crispr
|
EP3329003A2
(en)
|
2015-07-29 |
2018-06-06 |
Arbutus Biopharma Corporation |
Compositions and methods for silencing hepatitis b virus gene expression
|
US20170145475A1
(en)
|
2015-11-20 |
2017-05-25 |
Streck, Inc. |
Single spin process for blood plasma separation and plasma composition including preservative
|
US10010627B2
(en)
|
2016-06-03 |
2018-07-03 |
International Business Machines Corporation |
Modified polycationic polymers
|
US11506655B2
(en)
|
2016-07-29 |
2022-11-22 |
Streck, Inc. |
Suspension composition for hematology analysis control
|
WO2018093932A2
(en)
|
2016-11-16 |
2018-05-24 |
Immunomic Therapeutics, Inc. |
Nucleic acids for treatment of allergies
|
US11033572B2
(en)
|
2017-01-19 |
2021-06-15 |
Universiteit Gent |
Molecular adjuvants for enhanced cytosolic delivery of active agents
|
CA3061206A1
(en)
|
2017-04-22 |
2018-10-25 |
Immunomic Therapeutics, Inc. |
Improved lamp constructs
|
KR20240027895A
(ko)
|
2017-05-02 |
2024-03-04 |
이뮤노믹 쎄라퓨틱스, 인크. |
암 항원을 포함하는 lamp (리소솜 연관 막 단백질) 구축물
|
JP2021523185A
(ja)
|
2018-05-15 |
2021-09-02 |
イミュノミック セラピューティックス, インコーポレイテッドImmunomic Therapeutics, Inc. |
アレルゲンを含む改善されたlamp構築物
|
TW202043256A
(zh)
|
2019-01-10 |
2020-12-01 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
CA3153850A1
(en)
|
2019-10-18 |
2021-04-22 |
Teri Heiland |
Improved lamp constructs comprising cancer antigens
|
CN114980920A
(zh)
|
2019-11-18 |
2022-08-30 |
詹森生物科技公司 |
基于突变体calr和jak2的疫苗及其用途
|
WO2022009052A2
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
WO2022009049A1
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
WO2022009051A1
(en)
|
2020-07-06 |
2022-01-13 |
Janssen Biotech, Inc. |
A method for determining responsiveness to prostate cancer treatment
|
CN112237633B
(zh)
*
|
2020-10-22 |
2023-06-27 |
林君玉 |
一种pei/on复合物及其制备方法和用途
|
KR20230124927A
(ko)
|
2020-11-25 |
2023-08-28 |
아카제라 메디신즈, 인크. |
핵산 전달을 위한 지질 나노입자, 및 관련 사용 방법
|
GB202108176D0
(en)
|
2021-06-08 |
2021-07-21 |
Touchlight Ip Ltd |
Vector
|
IL308705A
(en)
|
2021-06-08 |
2024-01-01 |
Touchlight Ip Ltd |
LENTIVIRAL vector
|
WO2023201201A1
(en)
|
2022-04-10 |
2023-10-19 |
Immunomic Therapeutics, Inc. |
Bicistronic lamp constructs comprising immune response enhancing genes and methods of use thereof
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