FR2739292B1 - Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations - Google Patents
Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisationsInfo
- Publication number
- FR2739292B1 FR2739292B1 FR9511411A FR9511411A FR2739292B1 FR 2739292 B1 FR2739292 B1 FR 2739292B1 FR 9511411 A FR9511411 A FR 9511411A FR 9511411 A FR9511411 A FR 9511411A FR 2739292 B1 FR2739292 B1 FR 2739292B1
- Authority
- FR
- France
- Prior art keywords
- pharmaceutical composition
- nucleic acids
- composition useful
- transfecting nucleic
- transfecting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9511411A FR2739292B1 (fr) | 1995-09-28 | 1995-09-28 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
ZA968109A ZA968109B (en) | 1995-09-28 | 1996-09-26 | Pharmaceutical composition which is useful for the transfection of nucleic acids and uses thereof |
EP96932668A EP0854930A1 (fr) | 1995-09-28 | 1996-09-27 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
JP9513192A JPH11512704A (ja) | 1995-09-28 | 1996-09-27 | 核酸のトランスフェクションに有用な医薬組成物及びその使用 |
BR9610719A BR9610719A (pt) | 1995-09-28 | 1996-09-27 | Composição farmacêutica útil para a tranfecção de ao menos um ácido nucléico utilização desta composição e de um composto associando propiedades de fixão de dna a uma capacidade de vetorização nu clear deste dna |
KR1019980702282A KR19990063814A (ko) | 1995-09-28 | 1996-09-27 | 핵산 형질감염용으로 유용한 약학 조성물 및 이의 용도 |
SK400-98A SK40098A3 (en) | 1995-09-28 | 1996-09-27 | Pharmaceutical composition useful for nucleic acid transfection, and use thereof |
AU71361/96A AU720697B2 (en) | 1995-09-28 | 1996-09-27 | Pharmaceutical composition which is useful for the transfection of nucleic acids, and uses thereof |
HU9900317A HUP9900317A3 (en) | 1995-09-28 | 1996-09-27 | Pharmaceutical composition useful for nucleic acid transfection, and use thereof |
US09/043,856 US6153597A (en) | 1995-09-28 | 1996-09-27 | Pharmaceutical composition useful for nucleic acid transfection, and use thereof |
CZ98947A CZ94798A3 (cs) | 1995-09-28 | 1996-09-27 | Farmaceutická kompozice použitelná pro transfekci nukleových kyselin a její použití |
PCT/FR1996/001516 WO1997012051A1 (fr) | 1995-09-28 | 1996-09-27 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
CA002231064A CA2231064A1 (fr) | 1995-09-28 | 1996-09-27 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
IL12384996A IL123849A0 (en) | 1995-09-28 | 1996-09-28 | Pharmaceutical composition useful for nucleic acid transfection and use thereof |
MXPA/A/1998/001920A MXPA98001920A (en) | 1995-09-28 | 1998-03-11 | Pharmaceutical composition useful for the transfection of nucleic acids and its u |
NO981322A NO981322L (no) | 1995-09-28 | 1998-03-24 | Farmas÷ytiske preparater for bruk ved nukleinsyretransfeksjon, og deres anvendelse |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9511411A FR2739292B1 (fr) | 1995-09-28 | 1995-09-28 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2739292A1 FR2739292A1 (fr) | 1997-04-04 |
FR2739292B1 true FR2739292B1 (fr) | 1997-10-31 |
Family
ID=9483020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR9511411A Expired - Fee Related FR2739292B1 (fr) | 1995-09-28 | 1995-09-28 | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
Country Status (15)
Country | Link |
---|---|
US (1) | US6153597A (fr) |
EP (1) | EP0854930A1 (fr) |
JP (1) | JPH11512704A (fr) |
KR (1) | KR19990063814A (fr) |
AU (1) | AU720697B2 (fr) |
BR (1) | BR9610719A (fr) |
CA (1) | CA2231064A1 (fr) |
CZ (1) | CZ94798A3 (fr) |
FR (1) | FR2739292B1 (fr) |
HU (1) | HUP9900317A3 (fr) |
IL (1) | IL123849A0 (fr) |
NO (1) | NO981322L (fr) |
SK (1) | SK40098A3 (fr) |
WO (1) | WO1997012051A1 (fr) |
ZA (1) | ZA968109B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2750704B1 (fr) | 1996-07-04 | 1998-09-25 | Rhone Poulenc Rorer Sa | Procede de production d'adn therapeutique |
US6383811B2 (en) * | 1997-12-30 | 2002-05-07 | Mirus Corporation | Polyampholytes for delivering polyions to a cell |
IT1299583B1 (it) * | 1998-05-19 | 2000-03-16 | Vander Way Limited | Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica |
DE19925143A1 (de) * | 1999-06-02 | 2000-12-07 | Aventis Pharma Gmbh | Neue liposomale Vektorkomplexe und deren Verwendung für die Gentherapie |
DE19929104A1 (de) * | 1999-06-24 | 2000-12-28 | Aventis Pharma Gmbh | Neue Vektorkomplexe und deren Verwendung für die Gentherapie |
FR2814370B1 (fr) * | 2000-09-22 | 2004-08-20 | Centre Nat Rech Scient | Utilisation d'un complexe acide nucleique/pei pour le ciblage de cellules souches du cerveau |
IL156132A0 (en) * | 2000-11-27 | 2003-12-23 | Yissum Res Dev Co | Transfection of human embryonic stem cells |
JP2005511761A (ja) * | 2001-07-10 | 2005-04-28 | ノース・キャロライナ・ステイト・ユニヴァーシティ | ナノ粒子送達ビヒクル |
FR2829136B1 (fr) | 2001-08-29 | 2006-11-17 | Aventis Pharma Sa | Derives lipidiques d'aminoglycosides |
ITMI20011986A1 (it) * | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
US7060498B1 (en) | 2001-11-28 | 2006-06-13 | Genta Salus Llc | Polycationic water soluble copolymer and method for transferring polyanionic macromolecules across biological barriers |
JP5407862B2 (ja) * | 2006-10-04 | 2014-02-05 | サントル・ナシオナル・ドゥ・ラ・ルシェルシュ・シアンティフィーク(セーエヌエールエス) | siRNAおよび脂質性4,5−二置換2−デオキシストレプタミン環アミノグリコシド誘導体を含む組成物ならびにその用途 |
EP3034539A1 (fr) * | 2014-12-19 | 2016-06-22 | Ethris GmbH | Compositions pour l'introduction d'acides nucléiques dans des cellules |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2646161B1 (fr) * | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
FR2645866B1 (fr) * | 1989-04-17 | 1991-07-05 | Centre Nat Rech Scient | Nouvelles lipopolyamines, leur preparation et leur emploi |
US5286634A (en) * | 1989-09-28 | 1994-02-15 | Stadler Joan K | Synergistic method for host cell transformation |
US5334761A (en) * | 1992-08-28 | 1994-08-02 | Life Technologies, Inc. | Cationic lipids |
US5631237A (en) * | 1992-12-22 | 1997-05-20 | Dzau; Victor J. | Method for producing in vivo delivery of therapeutic agents via liposomes |
SG54115A1 (en) * | 1993-04-27 | 1998-11-16 | Gerber Scient Products Inc | Thermal printing apparatus with improved power supply |
FR2722506B1 (fr) * | 1994-07-13 | 1996-08-14 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucleiques, preparation et utilisations |
-
1995
- 1995-09-28 FR FR9511411A patent/FR2739292B1/fr not_active Expired - Fee Related
-
1996
- 1996-09-26 ZA ZA968109A patent/ZA968109B/xx unknown
- 1996-09-27 KR KR1019980702282A patent/KR19990063814A/ko not_active Application Discontinuation
- 1996-09-27 SK SK400-98A patent/SK40098A3/sk unknown
- 1996-09-27 CZ CZ98947A patent/CZ94798A3/cs unknown
- 1996-09-27 WO PCT/FR1996/001516 patent/WO1997012051A1/fr not_active Application Discontinuation
- 1996-09-27 US US09/043,856 patent/US6153597A/en not_active Expired - Fee Related
- 1996-09-27 BR BR9610719A patent/BR9610719A/pt unknown
- 1996-09-27 HU HU9900317A patent/HUP9900317A3/hu unknown
- 1996-09-27 JP JP9513192A patent/JPH11512704A/ja not_active Ceased
- 1996-09-27 AU AU71361/96A patent/AU720697B2/en not_active Ceased
- 1996-09-27 EP EP96932668A patent/EP0854930A1/fr not_active Withdrawn
- 1996-09-27 CA CA002231064A patent/CA2231064A1/fr not_active Abandoned
- 1996-09-28 IL IL12384996A patent/IL123849A0/xx unknown
-
1998
- 1998-03-24 NO NO981322A patent/NO981322L/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP0854930A1 (fr) | 1998-07-29 |
JPH11512704A (ja) | 1999-11-02 |
FR2739292A1 (fr) | 1997-04-04 |
HUP9900317A3 (en) | 2001-10-29 |
WO1997012051A1 (fr) | 1997-04-03 |
MX9801920A (es) | 1998-08-30 |
BR9610719A (pt) | 1999-07-13 |
CZ94798A3 (cs) | 1998-07-15 |
KR19990063814A (ko) | 1999-07-26 |
IL123849A0 (en) | 1998-10-30 |
AU720697B2 (en) | 2000-06-08 |
AU7136196A (en) | 1997-04-17 |
SK40098A3 (en) | 1998-09-09 |
NO981322D0 (no) | 1998-03-24 |
ZA968109B (en) | 1997-04-21 |
CA2231064A1 (fr) | 1997-04-03 |
US6153597A (en) | 2000-11-28 |
NO981322L (no) | 1998-03-24 |
HUP9900317A2 (hu) | 1999-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name | ||
ST | Notification of lapse |