ES8304949A1 - "procedimiento perfeccionado de preparacion de 2,4-diamino-5-(3',4',5'-trimetoxi-bencil)-pirimidina". - Google Patents

"procedimiento perfeccionado de preparacion de 2,4-diamino-5-(3',4',5'-trimetoxi-bencil)-pirimidina".

Info

Publication number
ES8304949A1
ES8304949A1 ES513482A ES513482A ES8304949A1 ES 8304949 A1 ES8304949 A1 ES 8304949A1 ES 513482 A ES513482 A ES 513482A ES 513482 A ES513482 A ES 513482A ES 8304949 A1 ES8304949 A1 ES 8304949A1
Authority
ES
Spain
Prior art keywords
general formula
compound
trimethoxy
image
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513482A
Other languages
English (en)
Spanish (es)
Other versions
ES513482A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES513482A0 publication Critical patent/ES513482A0/es
Publication of ES8304949A1 publication Critical patent/ES8304949A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES513482A 1981-06-26 1982-06-25 "procedimiento perfeccionado de preparacion de 2,4-diamino-5-(3',4',5'-trimetoxi-bencil)-pirimidina". Expired ES8304949A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811869A HU187370B (en) 1981-06-26 1981-06-26 Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (2)

Publication Number Publication Date
ES513482A0 ES513482A0 (es) 1983-04-01
ES8304949A1 true ES8304949A1 (es) 1983-04-01

Family

ID=10956594

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513482A Expired ES8304949A1 (es) 1981-06-26 1982-06-25 "procedimiento perfeccionado de preparacion de 2,4-diamino-5-(3',4',5'-trimetoxi-bencil)-pirimidina".

Country Status (21)

Country Link
JP (1) JPS5838266A (it)
AT (1) AT387961B (it)
AU (1) AU547823B2 (it)
BE (1) BE893611A (it)
CA (1) CA1174679A (it)
CH (1) CH648834A5 (it)
CS (1) CS244908B2 (it)
DD (1) DD202703A5 (it)
DK (1) DK155434C (it)
ES (1) ES8304949A1 (it)
FI (1) FI76790C (it)
FR (1) FR2508450B1 (it)
GB (1) GB2104508B (it)
GR (1) GR76159B (it)
HU (1) HU187370B (it)
IE (1) IE53466B1 (it)
IL (1) IL66132A (it)
IT (1) IT1190889B (it)
SE (1) SE451133B (it)
SU (1) SU1145929A3 (it)
YU (1) YU42774B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743221A (en) * 1953-05-26 1956-01-11 Wellcome Found Improvements in or relating to the manufacture of acrylonitriles
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (it) * 1960-09-02
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
FI822268A0 (fi) 1982-06-24
IE53466B1 (en) 1988-11-23
DD202703A5 (de) 1983-09-28
IT8222035A0 (it) 1982-06-24
FR2508450A1 (fr) 1982-12-31
ES513482A0 (es) 1983-04-01
JPS5838266A (ja) 1983-03-05
AU547823B2 (en) 1985-11-07
YU138582A (en) 1984-10-31
GB2104508A (en) 1983-03-09
DK155434C (da) 1989-09-18
IT1190889B (it) 1988-02-24
ATA244982A (de) 1988-09-15
FR2508450B1 (fr) 1986-01-03
DK155434B (da) 1989-04-10
IL66132A (en) 1985-04-30
IE821520L (en) 1982-12-26
AT387961B (de) 1989-04-10
AU8534682A (en) 1983-01-06
FI76790B (fi) 1988-08-31
HU187370B (en) 1985-12-28
FI76790C (fi) 1988-12-12
CS244908B2 (en) 1986-08-14
CA1174679A (en) 1984-09-18
IL66132A0 (en) 1982-09-30
FI822268L (fi) 1982-12-27
DK288082A (da) 1982-12-27
CH648834A5 (de) 1985-04-15
GR76159B (it) 1984-08-03
SE8203914L (sv) 1982-12-27
BE893611A (fr) 1982-12-23
SU1145929A3 (ru) 1985-03-15
SE451133B (sv) 1987-09-07
CS471782A2 (en) 1985-09-17
YU42774B (en) 1988-12-31
SE8203914D0 (sv) 1982-06-23
GB2104508B (en) 1985-01-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603