FR2508450B1 - Perfectionnements apportes aux procedes pour la preparation de la 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidine - Google Patents

Perfectionnements apportes aux procedes pour la preparation de la 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidine

Info

Publication number
FR2508450B1
FR2508450B1 FR8211151A FR8211151A FR2508450B1 FR 2508450 B1 FR2508450 B1 FR 2508450B1 FR 8211151 A FR8211151 A FR 8211151A FR 8211151 A FR8211151 A FR 8211151A FR 2508450 B1 FR2508450 B1 FR 2508450B1
Authority
FR
France
Prior art keywords
trimethoxy
diamino
pyrimidine
benzyl
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8211151A
Other languages
English (en)
Other versions
FR2508450A1 (fr
Inventor
Ivan Beck
Imre Biro
Andras Dietz
Elemer Jakfalvi
Laszlo Ladanyi
Istvan Simonyi
Zoltan Takacs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2508450A1 publication Critical patent/FR2508450A1/fr
Application granted granted Critical
Publication of FR2508450B1 publication Critical patent/FR2508450B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR8211151A 1981-06-26 1982-06-25 Perfectionnements apportes aux procedes pour la preparation de la 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidine Expired FR2508450B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811869A HU187370B (en) 1981-06-26 1981-06-26 Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (2)

Publication Number Publication Date
FR2508450A1 FR2508450A1 (fr) 1982-12-31
FR2508450B1 true FR2508450B1 (fr) 1986-01-03

Family

ID=10956594

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8211151A Expired FR2508450B1 (fr) 1981-06-26 1982-06-25 Perfectionnements apportes aux procedes pour la preparation de la 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidine

Country Status (21)

Country Link
JP (1) JPS5838266A (fr)
AT (1) AT387961B (fr)
AU (1) AU547823B2 (fr)
BE (1) BE893611A (fr)
CA (1) CA1174679A (fr)
CH (1) CH648834A5 (fr)
CS (1) CS244908B2 (fr)
DD (1) DD202703A5 (fr)
DK (1) DK155434C (fr)
ES (1) ES8304949A1 (fr)
FI (1) FI76790C (fr)
FR (1) FR2508450B1 (fr)
GB (1) GB2104508B (fr)
GR (1) GR76159B (fr)
HU (1) HU187370B (fr)
IE (1) IE53466B1 (fr)
IL (1) IL66132A (fr)
IT (1) IT1190889B (fr)
SE (1) SE451133B (fr)
SU (1) SU1145929A3 (fr)
YU (1) YU42774B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743221A (en) * 1953-05-26 1956-01-11 Wellcome Found Improvements in or relating to the manufacture of acrylonitriles
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (fr) * 1960-09-02
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
ATA244982A (de) 1988-09-15
FI76790B (fi) 1988-08-31
IE821520L (en) 1982-12-26
FI76790C (fi) 1988-12-12
GB2104508B (en) 1985-01-16
YU42774B (en) 1988-12-31
SE8203914L (sv) 1982-12-27
BE893611A (fr) 1982-12-23
CS471782A2 (en) 1985-09-17
DK288082A (da) 1982-12-27
DK155434B (da) 1989-04-10
JPS5838266A (ja) 1983-03-05
AU8534682A (en) 1983-01-06
GB2104508A (en) 1983-03-09
CH648834A5 (de) 1985-04-15
IL66132A0 (en) 1982-09-30
IT8222035A0 (it) 1982-06-24
SU1145929A3 (ru) 1985-03-15
AT387961B (de) 1989-04-10
HU187370B (en) 1985-12-28
AU547823B2 (en) 1985-11-07
DK155434C (da) 1989-09-18
ES513482A0 (es) 1983-04-01
SE451133B (sv) 1987-09-07
IE53466B1 (en) 1988-11-23
IT1190889B (it) 1988-02-24
FR2508450A1 (fr) 1982-12-31
ES8304949A1 (es) 1983-04-01
CS244908B2 (en) 1986-08-14
CA1174679A (fr) 1984-09-18
YU138582A (en) 1984-10-31
FI822268L (fi) 1982-12-27
FI822268A0 (fi) 1982-06-24
GR76159B (fr) 1984-08-03
DD202703A5 (de) 1983-09-28
IL66132A (en) 1985-04-30
SE8203914D0 (sv) 1982-06-23

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Legal Events

Date Code Title Description
ST Notification of lapse