IT8222035A0 - Procedimento perfezionato per lapreparazione della 2,4-diammino-5-(3',4',5'-trimetossi benzil)-pirimidina. - Google Patents

Procedimento perfezionato per lapreparazione della 2,4-diammino-5-(3',4',5'-trimetossi benzil)-pirimidina.

Info

Publication number
IT8222035A0
IT8222035A0 IT8222035A IT2203582A IT8222035A0 IT 8222035 A0 IT8222035 A0 IT 8222035A0 IT 8222035 A IT8222035 A IT 8222035A IT 2203582 A IT2203582 A IT 2203582A IT 8222035 A0 IT8222035 A0 IT 8222035A0
Authority
IT
Italy
Prior art keywords
diamino
pyrimidine
preparation
improved procedure
trimethoxy benzyl
Prior art date
Application number
IT8222035A
Other languages
English (en)
Other versions
IT1190889B (it
Inventor
Ivan Beck
Imre Biro
Andras Dietz
Elemer Jakfalvi
Laszlo Ladanyi
Istvan Simonyi
Zoltan Takacs
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT8222035A0 publication Critical patent/IT8222035A0/it
Application granted granted Critical
Publication of IT1190889B publication Critical patent/IT1190889B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IT22035/82A 1981-06-26 1982-06-24 Procedimento perfezionato per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina IT1190889B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811869A HU187370B (en) 1981-06-26 1981-06-26 Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (2)

Publication Number Publication Date
IT8222035A0 true IT8222035A0 (it) 1982-06-24
IT1190889B IT1190889B (it) 1988-02-24

Family

ID=10956594

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22035/82A IT1190889B (it) 1981-06-26 1982-06-24 Procedimento perfezionato per la preparazione della 2,4-diammino-5-(3',4',5',trimetossibenzil)-pirimidina

Country Status (21)

Country Link
JP (1) JPS5838266A (it)
AT (1) AT387961B (it)
AU (1) AU547823B2 (it)
BE (1) BE893611A (it)
CA (1) CA1174679A (it)
CH (1) CH648834A5 (it)
CS (1) CS244908B2 (it)
DD (1) DD202703A5 (it)
DK (1) DK155434C (it)
ES (1) ES8304949A1 (it)
FI (1) FI76790C (it)
FR (1) FR2508450B1 (it)
GB (1) GB2104508B (it)
GR (1) GR76159B (it)
HU (1) HU187370B (it)
IE (1) IE53466B1 (it)
IL (1) IL66132A (it)
IT (1) IT1190889B (it)
SE (1) SE451133B (it)
SU (1) SU1145929A3 (it)
YU (1) YU42774B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743221A (en) * 1953-05-26 1956-01-11 Wellcome Found Improvements in or relating to the manufacture of acrylonitriles
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (it) * 1960-09-02
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
ATA244982A (de) 1988-09-15
FI76790B (fi) 1988-08-31
IE821520L (en) 1982-12-26
FI76790C (fi) 1988-12-12
GB2104508B (en) 1985-01-16
YU42774B (en) 1988-12-31
SE8203914L (sv) 1982-12-27
BE893611A (fr) 1982-12-23
CS471782A2 (en) 1985-09-17
DK288082A (da) 1982-12-27
DK155434B (da) 1989-04-10
JPS5838266A (ja) 1983-03-05
AU8534682A (en) 1983-01-06
GB2104508A (en) 1983-03-09
CH648834A5 (de) 1985-04-15
IL66132A0 (en) 1982-09-30
SU1145929A3 (ru) 1985-03-15
AT387961B (de) 1989-04-10
HU187370B (en) 1985-12-28
AU547823B2 (en) 1985-11-07
DK155434C (da) 1989-09-18
ES513482A0 (es) 1983-04-01
SE451133B (sv) 1987-09-07
IE53466B1 (en) 1988-11-23
IT1190889B (it) 1988-02-24
FR2508450A1 (fr) 1982-12-31
ES8304949A1 (es) 1983-04-01
FR2508450B1 (fr) 1986-01-03
CS244908B2 (en) 1986-08-14
CA1174679A (en) 1984-09-18
YU138582A (en) 1984-10-31
FI822268L (fi) 1982-12-27
FI822268A0 (fi) 1982-06-24
GR76159B (it) 1984-08-03
DD202703A5 (de) 1983-09-28
IL66132A (en) 1985-04-30
SE8203914D0 (sv) 1982-06-23

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