DD202703A5 - Verfahren zur herstellung des 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidin - Google Patents

Verfahren zur herstellung des 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidin Download PDF

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Publication number
DD202703A5
DD202703A5 DD82241097A DD24109782A DD202703A5 DD 202703 A5 DD202703 A5 DD 202703A5 DD 82241097 A DD82241097 A DD 82241097A DD 24109782 A DD24109782 A DD 24109782A DD 202703 A5 DD202703 A5 DD 202703A5
Authority
DD
German Democratic Republic
Prior art keywords
trimethoxy
general formula
compound
guanidine
benzyl
Prior art date
Application number
DD82241097A
Other languages
German (de)
English (en)
Inventor
Ivan Beck
Imre Biro
Andras Dietz
Elemer Jakfalvi
Laszlo Ladanyi
Istvan Simonyi
Zoltan Takacz
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DD202703A5 publication Critical patent/DD202703A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DD82241097A 1981-06-26 1982-06-25 Verfahren zur herstellung des 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidin DD202703A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811869A HU187370B (en) 1981-06-26 1981-06-26 Improved process for producing 2,4-diamino-5-bracket-3-comma above, 4-comma above,5-comma above-trimethoxy-benzyl-bracket closed-pyrimidine

Publications (1)

Publication Number Publication Date
DD202703A5 true DD202703A5 (de) 1983-09-28

Family

ID=10956594

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82241097A DD202703A5 (de) 1981-06-26 1982-06-25 Verfahren zur herstellung des 2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-pyrimidin

Country Status (21)

Country Link
JP (1) JPS5838266A (it)
AT (1) AT387961B (it)
AU (1) AU547823B2 (it)
BE (1) BE893611A (it)
CA (1) CA1174679A (it)
CH (1) CH648834A5 (it)
CS (1) CS244908B2 (it)
DD (1) DD202703A5 (it)
DK (1) DK155434C (it)
ES (1) ES8304949A1 (it)
FI (1) FI76790C (it)
FR (1) FR2508450B1 (it)
GB (1) GB2104508B (it)
GR (1) GR76159B (it)
HU (1) HU187370B (it)
IE (1) IE53466B1 (it)
IL (1) IL66132A (it)
IT (1) IT1190889B (it)
SE (1) SE451133B (it)
SU (1) SU1145929A3 (it)
YU (1) YU42774B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2602507B1 (fr) * 1986-08-08 1989-06-09 Sanofi Pharma Procede de preparation de diamino-2,4 benzyl-5 pyrimidines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743221A (en) * 1953-05-26 1956-01-11 Wellcome Found Improvements in or relating to the manufacture of acrylonitriles
DE1303727B (de) * 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
NL122146C (it) * 1960-09-02
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes
DE2635765C3 (de) * 1976-08-09 1979-02-08 Ludwig Heumann & Co Gmbh, 8500 Nuernberg Verfahren zur Herstellung von 2,4-EMamino-5-(3',4'r5'-trimethoxybenzyl)-pyrimidin
US4115650A (en) * 1976-11-17 1978-09-19 Hoffmann-La Roche Inc. Process for preparing 2,4-diamino-5-(substituted benzyl)-pyrimidines
DE2730467A1 (de) * 1977-07-06 1979-01-18 Basf Ag Benzylpyrimidine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
ATA244982A (de) 1988-09-15
FI76790B (fi) 1988-08-31
IE821520L (en) 1982-12-26
FI76790C (fi) 1988-12-12
GB2104508B (en) 1985-01-16
YU42774B (en) 1988-12-31
SE8203914L (sv) 1982-12-27
BE893611A (fr) 1982-12-23
CS471782A2 (en) 1985-09-17
DK288082A (da) 1982-12-27
DK155434B (da) 1989-04-10
JPS5838266A (ja) 1983-03-05
AU8534682A (en) 1983-01-06
GB2104508A (en) 1983-03-09
CH648834A5 (de) 1985-04-15
IL66132A0 (en) 1982-09-30
IT8222035A0 (it) 1982-06-24
SU1145929A3 (ru) 1985-03-15
AT387961B (de) 1989-04-10
HU187370B (en) 1985-12-28
AU547823B2 (en) 1985-11-07
DK155434C (da) 1989-09-18
ES513482A0 (es) 1983-04-01
SE451133B (sv) 1987-09-07
IE53466B1 (en) 1988-11-23
IT1190889B (it) 1988-02-24
FR2508450A1 (fr) 1982-12-31
ES8304949A1 (es) 1983-04-01
FR2508450B1 (fr) 1986-01-03
CS244908B2 (en) 1986-08-14
CA1174679A (en) 1984-09-18
YU138582A (en) 1984-10-31
FI822268L (fi) 1982-12-27
FI822268A0 (fi) 1982-06-24
GR76159B (it) 1984-08-03
IL66132A (en) 1985-04-30
SE8203914D0 (sv) 1982-06-23

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