ES474852A1 - Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado - Google Patents

Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado

Info

Publication number
ES474852A1
ES474852A1 ES474852A ES474852A ES474852A1 ES 474852 A1 ES474852 A1 ES 474852A1 ES 474852 A ES474852 A ES 474852A ES 474852 A ES474852 A ES 474852A ES 474852 A1 ES474852 A1 ES 474852A1
Authority
ES
Spain
Prior art keywords
guest
polypeptide
transformed
expression
bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474852A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25306290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES474852(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ES474852A1 publication Critical patent/ES474852A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
ES474852A 1977-11-08 1978-11-06 Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado Expired ES474852A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84969277A 1977-11-08 1977-11-08

Publications (1)

Publication Number Publication Date
ES474852A1 true ES474852A1 (es) 1979-12-01

Family

ID=25306290

Family Applications (1)

Application Number Title Priority Date Filing Date
ES474852A Expired ES474852A1 (es) 1977-11-08 1978-11-06 Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado

Country Status (30)

Country Link
EP (1) EP0001929B1 (cg-RX-API-DMAC10.html)
JP (2) JPS54163600A (cg-RX-API-DMAC10.html)
AT (1) AT373279B (cg-RX-API-DMAC10.html)
BG (1) BG38165A3 (cg-RX-API-DMAC10.html)
CA (1) CA1215921A (cg-RX-API-DMAC10.html)
CH (1) CH662128A5 (cg-RX-API-DMAC10.html)
DD (1) DD142561A5 (cg-RX-API-DMAC10.html)
DE (2) DE2862495D1 (cg-RX-API-DMAC10.html)
DK (1) DK173092B1 (cg-RX-API-DMAC10.html)
ES (1) ES474852A1 (cg-RX-API-DMAC10.html)
FI (1) FI783365A7 (cg-RX-API-DMAC10.html)
GB (1) GB2007676B (cg-RX-API-DMAC10.html)
GR (1) GR71906B (cg-RX-API-DMAC10.html)
HK (1) HK87184A (cg-RX-API-DMAC10.html)
IE (1) IE47891B1 (cg-RX-API-DMAC10.html)
IL (1) IL55892A (cg-RX-API-DMAC10.html)
IT (1) IT1100477B (cg-RX-API-DMAC10.html)
KE (1) KE3447A (cg-RX-API-DMAC10.html)
MW (1) MW3378A1 (cg-RX-API-DMAC10.html)
MY (1) MY8500762A (cg-RX-API-DMAC10.html)
NL (2) NL7811042A (cg-RX-API-DMAC10.html)
NO (1) NO783722L (cg-RX-API-DMAC10.html)
NZ (1) NZ188836A (cg-RX-API-DMAC10.html)
PH (1) PH16937A (cg-RX-API-DMAC10.html)
PL (1) PL210787A1 (cg-RX-API-DMAC10.html)
PT (1) PT68755A (cg-RX-API-DMAC10.html)
SE (1) SE501005C2 (cg-RX-API-DMAC10.html)
SG (1) SG56884G (cg-RX-API-DMAC10.html)
YU (2) YU257278A (cg-RX-API-DMAC10.html)
ZA (1) ZA786304B (cg-RX-API-DMAC10.html)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171824A (en) * 1977-05-23 1979-10-23 Foster Edwin E Bicyle
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (cg-RX-API-DMAC10.html) * 1979-09-12 1982-09-03 Univ California
AU553400B2 (en) * 1980-01-08 1986-07-17 Biogen, Inc. Recombinant dna for producing interferon
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4769326A (en) * 1980-02-29 1988-09-06 The Regents Of The University Of California Expression linkers
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
CA1341604C (en) 1980-04-03 2010-05-04 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
IE52122B1 (en) * 1980-08-25 1987-06-24 Univ California Somatostatin or somatostatin precursors
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
US6692941B1 (en) 1980-08-26 2004-02-17 The Regents Of The University Of California Bovine growth hormone
NZ198445A (en) * 1980-09-25 1984-05-31 Genentech Inc Production of human fibroblast interferon by recombinant dna technology
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
US4624926A (en) * 1981-01-02 1986-11-25 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4666836A (en) * 1981-01-02 1987-05-19 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
JPS57181098A (en) * 1981-04-30 1982-11-08 Japan Found Cancer Novel recombinant dna
JPS58996A (ja) * 1981-06-01 1983-01-06 ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− 細菌中での牛成長ホルモン遺伝子のクロ−ン化
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
US4650761A (en) * 1981-11-27 1987-03-17 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cell
US4863855A (en) * 1982-05-14 1989-09-05 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4530904A (en) * 1982-09-03 1985-07-23 Eli Lilly And Company Method for conferring bacteriophage resistance to bacteria
EP0108045B1 (en) * 1982-10-25 1988-12-07 Monsanto Company Reca promoter dependent polypeptide production
DE3381568D1 (de) * 1983-01-13 1990-06-21 Max Planck Gesellschaft Verfahren zum einbringen von expressionsfaehigen genen in pflanzenzellgenome und hybride ti plasmidvektoren enthaltende agrobacterium-staemme verwendbar in diesem verfahren.
US4888286A (en) * 1984-02-06 1989-12-19 Creative Biomolecules, Inc. Production of gene and protein analogs through synthetic gene design using double stranded synthetic oligonucleotides
DE3585170D1 (de) 1984-03-06 1992-02-27 Lilly Co Eli Expressionsvektoren fuer rinderwachstumshormonderivate.
GB8407044D0 (en) * 1984-03-19 1984-04-26 Fujisawa Pharmaceutical Co Producing human insulin
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
IT1198443B (it) * 1984-03-30 1988-12-21 Serono Ist Farm Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
CA1213537A (en) * 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
NL8401781A (nl) * 1984-06-04 1986-01-02 Rijksuniversiteit Leiden En Pr Werkwijze voor het activeren van promotoren van bacterien.
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
DE3686365T3 (de) 1985-06-20 2000-07-27 Fujisawa Pharmaceutical Co., Ltd. Herstellungsverfahren für humanes atriales natriuretisches Polypeptid.
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha
US5254678A (en) * 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
DE4244915C2 (de) * 1992-08-14 1998-12-03 Widmar Prof Dr Tanner DNA-Moleküle codierend Proteine, die an der O-Glykosylierung von Proteinen beteiligt sind
CA2244891C (en) * 1996-02-09 2008-12-30 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
DE19729769A1 (de) 1997-07-11 1999-01-14 Cardiogene Gentherapeutische S Transfektionssystem, seine Herstellung und Verwendung in der somatischen Gentherapie
DE19905501B4 (de) 1999-02-10 2005-05-19 MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
DE102009001793A1 (de) 2009-03-24 2010-10-07 Evonik Degussa Gmbh Prepregs und daraus hergestellte Formkörper
DE102009001806A1 (de) 2009-03-24 2010-09-30 Evonik Degussa Gmbh Prepregs und daraus bei niedriger Temperatur hergestellte Formkörper
DE102010029355A1 (de) 2010-05-27 2011-12-01 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper
DE102010041247A1 (de) 2010-09-23 2012-03-29 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung in Lösung
DE102011006163A1 (de) 2011-03-25 2012-09-27 Evonik Degussa Gmbh Lagerstabile Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung mit flüssigen Harzkomponenten
ES2880621T3 (es) 2016-12-02 2021-11-25 Evonik Degussa Gmbh Productos preimpregnados de poliuretano 1K estables al almacenamiento y cuerpos moldeados a partir de la composición de poliuretano producidos a partir de estos
BR112020023538A2 (pt) 2018-05-22 2021-05-04 Katherine Konstantin Sizov biossensor de receptor de etileno

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
DE2712615A1 (de) * 1977-03-18 1978-09-21 Max Planck Gesellschaft Verfahren zur herstellung von filamentoesen phagen als vektor fuer synthetische rekombinate
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein

Also Published As

Publication number Publication date
SE501005C2 (sv) 1994-10-17
PL210787A1 (cg-RX-API-DMAC10.html) 1980-04-21
NL930113I1 (cg-RX-API-DMAC10.html) 1993-10-18
AT373279B (de) 1984-01-10
HK87184A (en) 1984-11-16
ZA786304B (en) 1979-10-31
KE3447A (en) 1984-10-05
IT7829518A0 (it) 1978-11-07
EP0001929B1 (en) 1989-04-19
GB2007676A (en) 1979-05-23
DK173092B1 (da) 2000-01-10
IL55892A0 (en) 1979-01-31
PT68755A (en) 1978-12-01
FI783365A7 (fi) 1979-05-09
DK493778A (da) 1979-05-09
NO783722L (no) 1979-05-09
EP0001929A3 (en) 1979-06-13
ATA793478A (de) 1983-05-15
JPH0513630B2 (cg-RX-API-DMAC10.html) 1993-02-23
EP0001929A2 (en) 1979-05-16
DE2862495D1 (en) 1989-05-24
IE782193L (en) 1979-05-08
DE2848053A1 (de) 1979-05-10
GB2007676B (en) 1982-09-08
IT1100477B (it) 1985-09-28
BG38165A3 (bg) 1985-10-15
NL7811042A (nl) 1979-05-10
IE47891B1 (en) 1984-07-11
SG56884G (en) 1985-03-08
JP2694840B2 (ja) 1997-12-24
JPH07284394A (ja) 1995-10-31
NZ188836A (en) 1982-08-17
MY8500762A (en) 1985-12-31
SE7811461L (sv) 1979-05-09
IL55892A (en) 1983-10-31
DD142561A5 (de) 1980-07-02
CH662128A5 (de) 1987-09-15
PH16937A (en) 1984-04-24
JPS54163600A (en) 1979-12-26
YU236283A (en) 1988-08-31
GR71906B (cg-RX-API-DMAC10.html) 1983-08-12
MW3378A1 (en) 1980-03-12
CA1215921A (en) 1986-12-30
YU257278A (en) 1984-02-29

Similar Documents

Publication Publication Date Title
ES474852A1 (es) Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado
ES8305042A1 (es) "procedimiento para la obtencion de un plasmido de expresion para la expresion de un gen heterologo".
ES524986A0 (es) Metodo de obtencion del exprimido de una materia seleccionada que contiene renina.
ATE87663T1 (de) Verfahren zur herstellung von faktor-viii:c-typ- proteinen.
DK289688A (da) Ekspression af proapolipoprotein a-i.
ATE46536T1 (de) Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren.
ES8305413A1 (es) Un metodo para estabilizar y seleccionar celulas huesped quecontienen un adn recombinante
ATE66693T1 (de) Rekombinante dns-sequenzen, diese enthaltende vektoren und verfahren zur verwendung derselben.
DK160998C (da) Plasmid indeholdende dna fra en plasmidfraktion af b.thuringiensis, e.coli bakteriestamme indeholdende plasmidet, gensplejset e.coli bakteriestamme, fremgangsmaade til fremstilling af plasmidet, fremgangsmaade til at skabe en gensplejset e.coli bakteriestamme, fremgangsmaade til fremstilling af bacillus thuringiensis krystalprotein og fremgangsmaade til at opnaa insekticid virkning i et miljoe
ES2061482T3 (es) Metodo para la identificacion de secuencias de señal secretora para sintesis de proteina extracelular en bacillus.
AR241654A1 (es) Procedimiento para producir activador de plasminogeno de tejido humano.
DE3856241D1 (de) Verfahren zur Herstellug von transgene Zea mays-Pflanzen, die aus Protoplasten oder aus von Protopflasten erhaltenen Zellen regeneriert wurden
FI852547L (fi) Framstaellning av faktor viii och daertill hoerande produkter.
EP0088195A3 (en) Messenger rna, production and use thereof
NO950534L (no) Modufiserte soppceller og fremgangsmåter for fremstilling av rekombinante produkter
HUP9900876A2 (hu) Az alfa-hordotionin nagy treonintartalmú származékai
ES2006925A6 (es) Procedimiento para la preparacion de vectores de expresion.
ES8504255A1 (es) Procedimiento para la produccion de una hormona de crecimiento de porcino.
ES2058486T3 (es) Inmunogenos nativos y recombinantes del grupo b de eimeria tenella utiles como vacunas para las coccidiosis.
DE3485336D1 (de) Verfahren zur expression von alpha-1-antitrypsin in bakterien und dessen verwendung in therapeutischen zusammensetzungen sowie vektoren und bakterien fuer ein solches verfahren und deren herstellung.
DE3785798D1 (de) Verfahren zur gentechnologischengewinnung von proteinen unter verwendung gramnegativer wirtzellen.
ATE246249T1 (de) Für ammonium-transporter kodierende dna-sequenzen und dieser enthaltende, plasmide, bakterien, hefen und pflanzenzellen
ES8305415A1 (es) Un metodo para aumentar la produccion de proteinas por adn heterologo, en vectores de clonacion de plasmidos.
ES2111536T3 (es) Metodos y secuencias de acidos nucleicos para la expresion del operon de la sintasa de celulosa.
ES8403158A1 (es) Un metodo para crear un microorganismo capaz de producir unaproteina predeterminada por medio de expresion.