ES8603571A1 - Un procedimiento para preparar gamma-interferon de humano - Google Patents

Un procedimiento para preparar gamma-interferon de humano

Info

Publication number
ES8603571A1
ES8603571A1 ES541350A ES541350A ES8603571A1 ES 8603571 A1 ES8603571 A1 ES 8603571A1 ES 541350 A ES541350 A ES 541350A ES 541350 A ES541350 A ES 541350A ES 8603571 A1 ES8603571 A1 ES 8603571A1
Authority
ES
Spain
Prior art keywords
gene
interferon
human gamma
preparation
carrying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541350A
Other languages
English (en)
Other versions
ES541350A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8603571A1 publication Critical patent/ES8603571A1/es
Publication of ES541350A0 publication Critical patent/ES541350A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR GAMMA=INTERFERON DE HUMANO. COMPRENDE: A) INCORPORAR UN GEN SINTETIZADO VENTAJOSAMENTE EN FORMA DE VARIOS FRAGMENTOS, QUE SON LIGADOS ENZIMATICAMENTE PARA FORMAR SECUENCIAS PARCIALES MAYORES Y QUE CONTIENE UNA SECUENCIA DE ADN I EN UN VECTOR; B) INCORPORAR ESTE VECTOR EN PLASMIDOS HIBRIDOS Y AMPLIFICADAS EN ORGANISMOS HOSPEDANTES COMO E.COLI.; C) EXPRESAR EN ESTE HUESPED DICHO GEN SINTETICO; D) A CONTINUACION DEL GEN SIGUEN DOS CODONES DE DETENCION; Y E) ESCINDIR EL VECTOR CON LAS ENZIMAS DE RESTRICCION ECO RI Y SAL I, Y EN LUGARES DE ESCISION SE INSERTA UNA SECUENCIA DE ADN II.
ES541350A 1984-03-19 1985-03-18 Un procedimiento para preparar gamma-interferon de humano Granted ES541350A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843409966 DE3409966A1 (de) 1984-03-19 1984-03-19 Gentechnologisches verfahren zur herstellung von human-gammainterferon und mittel zur durchfuehrung dieses verfahrens

Publications (2)

Publication Number Publication Date
ES8603571A1 true ES8603571A1 (es) 1985-12-16
ES541350A0 ES541350A0 (es) 1985-12-16

Family

ID=6230903

Family Applications (1)

Application Number Title Priority Date Filing Date
ES541350A Granted ES541350A0 (es) 1984-03-19 1985-03-18 Un procedimiento para preparar gamma-interferon de humano

Country Status (16)

Country Link
EP (1) EP0155590A3 (es)
JP (1) JPS60210996A (es)
KR (1) KR850006704A (es)
AU (1) AU576226B2 (es)
DE (1) DE3409966A1 (es)
DK (1) DK121985A (es)
ES (1) ES541350A0 (es)
FI (1) FI851037L (es)
GR (1) GR850679B (es)
HU (1) HUT37651A (es)
IL (1) IL74627A0 (es)
MA (1) MA20381A1 (es)
NO (1) NO851065L (es)
NZ (1) NZ211478A (es)
PT (1) PT80121B (es)
ZA (1) ZA851992B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3607835A1 (de) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
CN108484749B (zh) * 2018-03-27 2020-10-02 山东省医药生物技术研究中心（山东省病毒研究所） 一种重组可溶性人源骨靶向干扰素γ-1b及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8302778A1 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
ZA831094B (en) * 1982-02-22 1983-11-30 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human immune interferon-like polypeptides
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet

Also Published As

Publication number Publication date
FI851037L (fi) 1985-09-20
GR850679B (es) 1985-07-16
NZ211478A (en) 1988-10-28
HUT37651A (en) 1986-01-23
ZA851992B (en) 1986-08-27
AU576226B2 (en) 1988-08-18
DK121985A (da) 1985-09-20
IL74627A0 (en) 1985-06-30
PT80121A (de) 1985-04-01
EP0155590A2 (de) 1985-09-25
FI851037A0 (fi) 1985-03-15
PT80121B (de) 1987-01-05
DE3409966A1 (de) 1985-09-26
JPS60210996A (ja) 1985-10-23
NO851065L (no) 1985-09-20
KR850006704A (ko) 1985-10-16
AU4004785A (en) 1985-09-26
MA20381A1 (fr) 1985-10-01
DK121985D0 (da) 1985-03-18
ES541350A0 (es) 1985-12-16
EP0155590A3 (de) 1987-04-22

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