ES474852A1 - Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado - Google Patents

Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado

Info

Publication number
ES474852A1
ES474852A1 ES474852A ES474852A ES474852A1 ES 474852 A1 ES474852 A1 ES 474852A1 ES 474852 A ES474852 A ES 474852A ES 474852 A ES474852 A ES 474852A ES 474852 A1 ES474852 A1 ES 474852A1
Authority
ES
Spain
Prior art keywords
plasmid
render
bacterial host
polypeptide expression
transforming bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES474852A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25306290&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES474852(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ES474852A1 publication Critical patent/ES474852A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16

Abstract

Un método para la expresión en un huésped bacteriano transformado, de un polipéptido heterólogo con respecto al huésped en su estado no transformado cuyo método comprende: a) obtener una cantidad de huésped transformante, elemento individuales del mismo que contengan uno o más plásmidos que comprenden: 1) un regulador homólogo al huésped bacteriano en su estado no transformado y 2) en fase de lectura con el regulador, una codificación de inserción ADN para la secuencia de aminoácidos de un polipéptido heterólogo , de tal manera que las bacterias transformadas por el plásmido son capaces de expresar la secuencia de aminoácidos en forma recuperable, b) separar el huesped transformante en un medio adecuado para su crecimiento y c)provocar la expresión de dicho polipéptido.
ES474852A 1977-11-08 1978-11-06 Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado Expired ES474852A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84969277A 1977-11-08 1977-11-08

Publications (1)

Publication Number Publication Date
ES474852A1 true ES474852A1 (es) 1979-12-01

Family

ID=25306290

Family Applications (1)

Application Number Title Priority Date Filing Date
ES474852A Expired ES474852A1 (es) 1977-11-08 1978-11-06 Un metodo para la expresion,en un huesped bacteriano trans- formado de un polipeptido heterologo con respecto al huespeden su estado no transformado

Country Status (30)

Country Link
EP (1) EP0001929B1 (es)
JP (2) JPS54163600A (es)
AT (1) AT373279B (es)
BG (1) BG38165A3 (es)
CA (1) CA1215921A (es)
CH (1) CH662128A5 (es)
DD (1) DD142561A5 (es)
DE (2) DE2862495D1 (es)
DK (1) DK173092B1 (es)
ES (1) ES474852A1 (es)
FI (1) FI783365A (es)
GB (1) GB2007676B (es)
GR (1) GR71906B (es)
HK (1) HK87184A (es)
IE (1) IE47891B1 (es)
IL (1) IL55892A (es)
IT (1) IT1100477B (es)
KE (1) KE3447A (es)
MW (1) MW3378A1 (es)
MY (1) MY8500762A (es)
NL (2) NL7811042A (es)
NO (1) NO783722L (es)
NZ (1) NZ188836A (es)
PH (1) PH16937A (es)
PL (1) PL210787A1 (es)
PT (1) PT68755A (es)
SE (1) SE501005C2 (es)
SG (1) SG56884G (es)
YU (2) YU257278A (es)
ZA (1) ZA786304B (es)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171824A (en) * 1977-05-23 1979-10-23 Foster Edwin E Bicyle
US4411994A (en) * 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
FI792481A (fi) * 1978-08-11 1980-02-12 Univ California Syntes av enkaroytiskt protein genom anvaendning av mikro-organismer
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
ZA802992B (en) * 1979-06-01 1981-10-28 Univ California Human pre-growth hormone
FR2458584A1 (fr) * 1979-06-08 1981-01-02 Pasteur Institut Vecteurs pour le transfert et l'expression de materiel genetique dans une cellule eucaryote et procede pour la production d'une proteine determinee dans des cellules eucaryotes
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
GR70279B (es) * 1979-09-12 1982-09-03 Univ California
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
PT72322B (en) * 1980-01-08 1982-09-23 Biogen Nv Process for preparation of recombinant dna molecules and of polipeptides similar to human interferon
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
US6455275B1 (en) 1980-02-25 2002-09-24 The Trustees Of Columbia University In The City Of New York DNA construct for producing proteinaceous materials in eucaryotic cells
CA1200773A (en) * 1980-02-29 1986-02-18 William J. Rutter Expression linkers
US4769326A (en) * 1980-02-29 1988-09-06 The Regents Of The University Of California Expression linkers
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
ZA811368B (en) * 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
CA1202581A (en) * 1980-03-27 1986-04-01 Saran A. Narang Adaptor molecules for dna and their application to synthesis of gene-derived products
PT72786B (en) 1980-04-03 1983-01-10 Biogen Nv Process for producing dna sequences recombinant dna molecules and human fibroplast interferon-like polypeptides
US6610830B1 (en) 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
IE52122B1 (en) * 1980-08-25 1987-06-24 Univ California Somatostatin or somatostatin precursors
US6692941B1 (en) 1980-08-26 2004-02-17 The Regents Of The University Of California Bovine growth hormone
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
NZ198445A (en) * 1980-09-25 1984-05-31 Genentech Inc Production of human fibroblast interferon by recombinant dna technology
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
NZ199391A (en) * 1981-01-02 1985-12-13 Genentech Inc Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin
US4666836A (en) * 1981-01-02 1987-05-19 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4624926A (en) * 1981-01-02 1986-11-25 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
JPS57181098A (en) * 1981-04-30 1982-11-08 Japan Found Cancer Novel recombinant dna
JPS58996A (ja) * 1981-06-01 1983-01-06 ザ・ボ−ド・オブ・トラステイ−ズ・ミシガンステ−トユニバ−シテイ− 細菌中での牛成長ホルモン遺伝子のクロ−ン化
US5254463A (en) * 1981-09-18 1993-10-19 Genentech, Inc. Method for expression of bovine growth hormone
US4650761A (en) * 1981-11-27 1987-03-17 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cell
US4863855A (en) * 1982-05-14 1989-09-05 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4530904A (en) * 1982-09-03 1985-07-23 Eli Lilly And Company Method for conferring bacteriophage resistance to bacteria
DE3378638D1 (de) * 1982-10-25 1989-01-12 Monsanto Co Reca promoter dependent polypeptide production
ATE282692T1 (de) * 1983-01-13 2004-12-15 Max Planck Gesellschaft Nichtonkogenisches ti-plasmidvektorsystem und für das einschleusen expressionsfähiger gene in pflanzengenomen verwendbare rekombinante dna- moleküle
US4888286A (en) * 1984-02-06 1989-12-19 Creative Biomolecules, Inc. Production of gene and protein analogs through synthetic gene design using double stranded synthetic oligonucleotides
DE3585170D1 (de) 1984-03-06 1992-02-27 Lilly Co Eli Expressionsvektoren fuer rinderwachstumshormonderivate.
GB8407044D0 (en) * 1984-03-19 1984-04-26 Fujisawa Pharmaceutical Co Producing human insulin
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
IT1198443B (it) * 1984-03-30 1988-12-21 Serono Ist Farm Espressione genetica di polipeptidi ibridi contenenti la sequenza della somatostatina
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
CA1213537A (en) * 1984-05-01 1986-11-04 Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee Polypeptide expression method
NL8401781A (nl) * 1984-06-04 1986-01-02 Rijksuniversiteit Leiden En Pr Werkwijze voor het activeren van promotoren van bacterien.
US5489529A (en) * 1984-07-19 1996-02-06 De Boer; Herman A. DNA for expression of bovine growth hormone
EP0440311A1 (en) * 1985-06-20 1991-08-07 Fujisawa Pharmaceutical Co., Ltd. A process for the production of alpha-human atrial natriuretic polypeptide
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
US5017692A (en) * 1986-09-04 1991-05-21 Schering Corporation Truncated human interleukin-a alpha
US5254678A (en) * 1987-12-15 1993-10-19 Gene Shears Pty. Limited Ribozymes
DE4226971C2 (de) * 1992-08-14 1997-01-16 Widmar Prof Dr Tanner Modifizierte Pilzzellen und Verfahren zur Herstellung rekombinanter Produkte
AU735440B2 (en) * 1996-02-09 2001-07-05 Cornell Research Foundation Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
DE19729769A1 (de) 1997-07-11 1999-01-14 Cardiogene Gentherapeutische S Transfektionssystem, seine Herstellung und Verwendung in der somatischen Gentherapie
DE19905501B4 (de) 1999-02-10 2005-05-19 MediGene AG, Gesellschaft für molekularbiologische Kardiologie und Onkologie Verfahren zur Herstellung eines rekombinanten Adeno-assoziierten Virus, geeignete Mittel hierzu sowie Verwendung zur Herstellung eines Arzneimittels
DE102009001793A1 (de) 2009-03-24 2010-10-07 Evonik Degussa Gmbh Prepregs und daraus hergestellte Formkörper
DE102009001806A1 (de) 2009-03-24 2010-09-30 Evonik Degussa Gmbh Prepregs und daraus bei niedriger Temperatur hergestellte Formkörper
DE102010029355A1 (de) 2010-05-27 2011-12-01 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper
DE102010041247A1 (de) 2010-09-23 2012-03-29 Evonik Degussa Gmbh Verfahren zur Herstellung von lagerstabilen Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung in Lösung
DE102011006163A1 (de) 2011-03-25 2012-09-27 Evonik Degussa Gmbh Lagerstabile Polyurethan-Prepregs und daraus hergestellte Formkörper aus Polyurethanzusammensetzung mit flüssigen Harzkomponenten
EP3330311B1 (de) 2016-12-02 2021-05-05 Evonik Operations GmbH Lagerstabile 1k-polyurethan-prepregs und daraus hergestellte formkörper aus polyurethanzusammensetzung
EP3796832B1 (en) 2018-05-22 2024-01-03 Strella Biotechnology, Inc. Ethylene receptor biosensor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1521032A (en) * 1974-08-08 1978-08-09 Ici Ltd Biological treatment
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
US4082613A (en) * 1976-04-23 1978-04-04 The Regents Of The University Of Minnesota Process for the production of insulin by genetically transformed fungal cells
DE2712615A1 (de) * 1977-03-18 1978-09-21 Max Planck Gesellschaft Verfahren zur herstellung von filamentoesen phagen als vektor fuer synthetische rekombinate
US4366246A (en) * 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
FI792481A (fi) * 1978-08-11 1980-02-12 Univ California Syntes av enkaroytiskt protein genom anvaendning av mikro-organismer
US4431739A (en) * 1979-11-05 1984-02-14 Genentech, Inc. Transformant bacterial culture capable of expressing heterologous protein

Also Published As

Publication number Publication date
SE501005C2 (sv) 1994-10-17
EP0001929B1 (en) 1989-04-19
JPS54163600A (en) 1979-12-26
JP2694840B2 (ja) 1997-12-24
PT68755A (en) 1978-12-01
GR71906B (es) 1983-08-12
DK493778A (da) 1979-05-09
HK87184A (en) 1984-11-16
GB2007676B (en) 1982-09-08
YU236283A (en) 1988-08-31
DK173092B1 (da) 2000-01-10
PL210787A1 (es) 1980-04-21
MW3378A1 (en) 1980-03-12
SG56884G (en) 1985-03-08
NZ188836A (en) 1982-08-17
GB2007676A (en) 1979-05-23
KE3447A (en) 1984-10-05
CH662128A5 (de) 1987-09-15
NO783722L (no) 1979-05-09
PH16937A (en) 1984-04-24
AT373279B (de) 1984-01-10
IL55892A0 (en) 1979-01-31
ZA786304B (en) 1979-10-31
ATA793478A (de) 1983-05-15
EP0001929A3 (en) 1979-06-13
NL7811042A (nl) 1979-05-10
DE2848053A1 (de) 1979-05-10
IL55892A (en) 1983-10-31
IE782193L (en) 1979-05-08
JPH07284394A (ja) 1995-10-31
JPH0513630B2 (es) 1993-02-23
IT1100477B (it) 1985-09-28
MY8500762A (en) 1985-12-31
NL930113I1 (es) 1993-10-18
SE7811461L (sv) 1979-05-09
YU257278A (en) 1984-02-29
CA1215921A (en) 1986-12-30
FI783365A (fi) 1979-05-09
IE47891B1 (en) 1984-07-11
IT7829518A0 (it) 1978-11-07
BG38165A3 (en) 1985-10-15
DD142561A5 (de) 1980-07-02
DE2862495D1 (en) 1989-05-24
EP0001929A2 (en) 1979-05-16

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