ES458481A1 - Un procedimiento de preparacion de nuevos derivados de ben- zodiazepina. - Google Patents

Un procedimiento de preparacion de nuevos derivados de ben- zodiazepina.

Info

Publication number
ES458481A1
ES458481A1 ES458481A ES458481A ES458481A1 ES 458481 A1 ES458481 A1 ES 458481A1 ES 458481 A ES458481 A ES 458481A ES 458481 A ES458481 A ES 458481A ES 458481 A1 ES458481 A1 ES 458481A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
benzodiazepine derivatives
benzodiazepine
alkyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458481A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CM Industries SA
Original Assignee
CM Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CM Industries SA filed Critical CM Industries SA
Publication of ES458481A1 publication Critical patent/ES458481A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Abstract

Un procedimiento de preparación de nuevos derivados de benzodiazepina de fórmula, (Ver imagen 1), donde R2 representa un átomo de hidrógeno o un radical seleccionado entre los radicales alilo, propargilo.
ES458481A 1976-05-05 1977-05-04 Un procedimiento de preparacion de nuevos derivados de ben- zodiazepina. Expired ES458481A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB18492/76A GB1538164A (en) 1976-05-05 1976-05-05 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
ES458481A1 true ES458481A1 (es) 1978-04-01

Family

ID=10113358

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458481A Expired ES458481A1 (es) 1976-05-05 1977-05-04 Un procedimiento de preparacion de nuevos derivados de ben- zodiazepina.

Country Status (31)

Country Link
US (2) US4235897A (es)
JP (3) JPS52156883A (es)
AR (1) AR219924A1 (es)
AT (1) AT356655B (es)
AU (1) AU509147B2 (es)
BE (1) BE854249A (es)
CA (1) CA1083146A (es)
CH (2) CH620686A5 (es)
CS (3) CS207399B2 (es)
DD (1) DD129446A5 (es)
DE (2) DE2719607A1 (es)
DK (2) DK195177A (es)
EG (1) EG12724A (es)
ES (1) ES458481A1 (es)
FI (1) FI771413A (es)
FR (2) FR2350346A1 (es)
GB (1) GB1538164A (es)
GR (1) GR63203B (es)
HU (1) HU177573B (es)
IE (1) IE44830B1 (es)
IL (2) IL51998A (es)
MX (1) MX4720E (es)
NL (2) NL7704911A (es)
NO (2) NO771560L (es)
NZ (1) NZ184012A (es)
PH (1) PH12641A (es)
PT (1) PT66500B (es)
SE (2) SE431543B (es)
SU (1) SU888820A3 (es)
YU (1) YU41818B (es)
ZA (1) ZA772628B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2900017A1 (de) * 1978-01-10 1979-07-12 Clin Midy 3-alkoxycarbonyl-benzodiazepin- derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FR2460938A1 (fr) * 1979-07-12 1981-01-30 Cm Ind Procede d'obtention de benzodiazepines-1,4
DE3021107A1 (de) * 1980-06-04 1981-12-17 Hoechst Ag, 6000 Frankfurt Carbamoyloxyamino-1,4-benzodiazepine, verfahren zu irer herstellung und diese enthaltende arzneimittel
JPS6038380A (ja) * 1983-08-11 1985-02-27 Shionogi & Co Ltd １−ピペリジニル−１，４−ベンゾジアゼピン類の改良合成法
JPH04200396A (ja) * 1990-11-30 1992-07-21 Sanwa Kagaku Kenkyusho Co Ltd 過酸化水素の酵素学的高感度測定法及びそのための試薬
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
KR100668045B1 (ko) * 2005-08-17 2007-01-16 한국과학기술연구원 ω-[2-(폴리알킬렌옥시)에틸티오]알킬알콕시실레인유도체와 이의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US28315A (en) * 1860-05-15 Improvement in method of decomposing fats into fatty acids and glycerine
US3136815A (en) * 1959-12-10 1964-06-09 Hoffmann La Roche Amino substituted benzophenone oximes and derivatives thereof
US3236838A (en) * 1964-06-09 1966-02-22 Hoffmann La Roche Certain 1-substituted-benzodiazepin-2-one compounds
USRE28315E (en) 1964-06-15 1975-01-21 Cooc.hi
FR1497456A (fr) * 1964-06-15 1967-10-13 Clin Byla Ets Ortho-amino aryl cétimines, composés hétérocycliques qui s'y rattachent et prépaation de ces divers corps
US3812103A (en) * 1967-04-11 1974-05-21 Hoffmann La Roche 2,3-dihydro-1,4-benzodiazepines
CH500997A (de) * 1967-08-09 1970-12-31 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
CH498846A (de) * 1967-08-09 1970-11-15 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
US3657223A (en) * 1969-01-17 1972-04-18 Hoffmann La Roche Process for the preparation of benzodiazepin-2-one derivatives
IL33961A (en) * 1969-03-13 1973-03-30 Sparamedica Ag Benzodiazepine aminoalkyl carboxylates,their preparation and pharmaceutical compositions containing them
US3718646A (en) * 1970-10-05 1973-02-27 Upjohn Co N-lower alkenyl-2,3-dihydro-2-oxo-5-phenyl-1h-1,4-benzodiazepine-1-carboxamides
IT1044223B (it) * 1972-08-09 1980-03-20 Zambeletti Spa L I propargil 1 4 benzodiazepine

Also Published As

Publication number Publication date
NO813180L (no) 1977-11-08
NO771560L (no) 1977-11-08
JPS52156882A (en) 1977-12-27
FR2350346B1 (es) 1980-11-21
JPS5781472A (en) 1982-05-21
AU2481377A (en) 1978-11-09
CS207399B2 (en) 1981-07-31
NL7704912A (nl) 1977-11-08
AT356655B (de) 1980-05-12
GR63203B (en) 1979-10-08
IE44830L (en) 1977-11-05
CA1083146A (en) 1980-08-05
NL7704911A (nl) 1977-11-08
US4587245A (en) 1986-05-06
SE7705183L (sv) 1977-11-06
DE2719607C2 (es) 1987-07-16
IL51998A0 (en) 1977-07-31
AR219924A1 (es) 1980-09-30
JPS5711317B2 (es) 1982-03-03
ZA772628B (en) 1978-03-29
DK195177A (da) 1977-11-06
FR2350346A1 (fr) 1977-12-02
ATA320177A (de) 1979-10-15
JPS52156883A (en) 1977-12-27
NO149208B (no) 1983-11-28
PT66500B (fr) 1978-10-13
HU177573B (en) 1981-11-28
FR2350345A1 (fr) 1977-12-02
DK195077A (da) 1977-11-06
BE854249A (fr) 1977-11-04
YU41818B (en) 1988-02-29
FR2350345B1 (es) 1980-07-18
EG12724A (en) 1979-12-31
SE432099B (sv) 1984-03-19
DE2719607A1 (de) 1977-11-17
IL51998A (en) 1981-05-20
NZ184012A (en) 1981-11-19
FI771413A (es) 1977-11-06
CH620912A5 (es) 1980-12-31
DD129446A5 (de) 1978-01-18
YU113977A (en) 1982-08-31
CS207400B2 (en) 1981-07-31
IE44830B1 (en) 1982-04-07
US4235897A (en) 1980-11-25
CS207398B2 (en) 1981-07-31
JPS6137249B2 (es) 1986-08-22
PT66500A (fr) 1977-06-01
DE2719608A1 (de) 1977-11-24
NO149208C (no) 1984-03-07
MX4720E (es) 1982-08-13
PH12641A (en) 1979-07-11
AU509147B2 (en) 1980-04-24
GB1538164A (en) 1979-01-10
SU888820A3 (ru) 1981-12-07
CH620686A5 (es) 1980-12-15
IL58648A0 (en) 1980-02-29
SE431543B (sv) 1984-02-13
SE7705182L (sv) 1977-11-06

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202