ES452986A1 - Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico). - Google Patents

Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico).

Info

Publication number
ES452986A1
ES452986A1 ES452986A ES452986A ES452986A1 ES 452986 A1 ES452986 A1 ES 452986A1 ES 452986 A ES452986 A ES 452986A ES 452986 A ES452986 A ES 452986A ES 452986 A1 ES452986 A1 ES 452986A1
Authority
ES
Spain
Prior art keywords
dihydropyridine
preparation
therapeutic agent
dicarboxylic acid
acid diester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452986A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES452986A1 publication Critical patent/ES452986A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES452986A 1975-11-05 1976-11-04 Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico). Expired ES452986A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2549568A DE2549568C3 (de) 1975-11-05 1975-11-05 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ES452986A1 true ES452986A1 (es) 1977-12-16

Family

ID=5960951

Family Applications (2)

Application Number Title Priority Date Filing Date
ES452986A Expired ES452986A1 (es) 1975-11-05 1976-11-04 Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico).
ES463166A Expired ES463166A1 (es) 1975-11-05 1977-10-13 Procedimiento para preparar ester isobutilico del acido 2,6-dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1,4-dihidropiri- din-5-carboxilico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES463166A Expired ES463166A1 (es) 1975-11-05 1977-10-13 Procedimiento para preparar ester isobutilico del acido 2,6-dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1,4-dihidropiri- din-5-carboxilico.

Country Status (27)

Country Link
JP (1) JPS5259161A (da)
AT (1) AT352129B (da)
AU (1) AU498964B2 (da)
BE (1) BE847968A (da)
BG (6) BG25079A3 (da)
CA (1) CA1085406A (da)
CH (2) CH623038A5 (da)
CS (1) CS200499B2 (da)
DE (1) DE2549568C3 (da)
DK (1) DK146762C (da)
ES (2) ES452986A1 (da)
FI (1) FI60704C (da)
FR (1) FR2330395A1 (da)
GB (1) GB1516793A (da)
GR (1) GR61241B (da)
HK (1) HK12681A (da)
IE (1) IE43984B1 (da)
IL (1) IL50817A (da)
LU (2) LU88275I2 (da)
NL (2) NL175915C (da)
NO (1) NO145574C (da)
NZ (1) NZ182502A (da)
PL (2) PL106084B1 (da)
PT (1) PT65797B (da)
RO (1) RO70295A (da)
SE (1) SE423542B (da)
ZA (1) ZA766622B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146630A (en) * 1976-11-12 1979-03-27 Boehringer Mannheim Gmbh Blood pressure lowering and adrenergic β-receptor inhibiting 3-(4-phenoxymethylpiperidino)-propyl-phenyl ethers
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
JPS5982192U (ja) * 1982-11-27 1984-06-02 エムケ−精工株式会社 扉
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
BG25078A3 (en) 1978-07-12
PT65797B (de) 1978-05-12
BG24803A3 (en) 1978-05-12
ZA766622B (en) 1977-10-26
CS200499B2 (en) 1980-09-15
FR2330395A1 (fr) 1977-06-03
NL930035I1 (nl) 1993-08-02
IE43984L (en) 1977-05-05
AU1935876A (en) 1978-05-11
PL105940B1 (pl) 1979-11-30
BG24804A3 (en) 1978-05-12
IL50817A (en) 1979-07-25
AU498964B2 (en) 1979-03-29
ES463166A1 (es) 1978-07-16
NL930035I2 (nl) 1993-10-01
DK146762B (da) 1983-12-27
HK12681A (en) 1981-04-10
LU88275I2 (da) 1994-02-03
LU76133A1 (da) 1977-06-02
BG24805A3 (en) 1978-05-12
CA1085406A (en) 1980-09-09
SE423542B (sv) 1982-05-10
AT352129B (de) 1979-09-10
PL106084B1 (pl) 1979-11-30
FI763160A (da) 1977-05-06
DK146762C (da) 1984-06-12
NL175915C (nl) 1985-01-16
CH622779A5 (en) 1981-04-30
DK498476A (da) 1977-05-06
NO145574C (no) 1982-04-21
BG25079A3 (en) 1978-07-12
DE2549568C3 (de) 1981-10-29
DE2549568A1 (de) 1977-05-18
SE7612308L (sv) 1977-05-06
FR2330395B1 (da) 1978-12-22
NZ182502A (en) 1978-07-28
DE2549568B2 (de) 1980-08-21
IL50817A0 (en) 1977-01-31
NL7612198A (nl) 1977-05-09
GR61241B (en) 1978-10-12
FI60704B (fi) 1981-11-30
FI60704C (fi) 1982-03-10
BE847968A (fr) 1977-05-04
PT65797A (de) 1976-12-01
RO70295A (ro) 1981-08-17
JPS5259161A (en) 1977-05-16
CH623038A5 (en) 1981-05-15
NO763608L (da) 1977-05-06
ATA814276A (de) 1979-02-15
IE43984B1 (en) 1981-07-15
BG24668A3 (en) 1978-04-12
JPS5647185B2 (da) 1981-11-07
NO145574B (no) 1982-01-11
GB1516793A (en) 1978-07-05

Similar Documents

Publication Publication Date Title
DE3665711D1 (de) Novel guanidinomethylbenzoic acid derivatives
ES452986A1 (es) Procedimiento para preparar ester isobutilico de acido 2,6- dimetil-3-metoxicarbonil-4-(2'-nitrofenil)-1, 4-dihidropiri-din-5-carboxilico).
ES8705411A1 (es) Procedimiento para preparar derivados de 1-piperazinacarboxamida
DE3879258D1 (de) Praeparat gegen ulcus.
ATE39920T1 (de) Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung.
ES454063A1 (es) Un procedimiento para la preparacion de nuevos derivados delalcohol bencilico.
DE3164314D1 (en) Azolylalkyl derivatives, process for their preparation and their use as fungicides
SE7702130L (sv) Forfarande for framstellning av n-(merkaptoacyl)-histidiner
ES461785A1 (es) Un metodo para la preparacion de un ester de acido behenico.
JPS5212141A (en) Novel amino benzoic acid derivatives, their preparation, and pharmaceu tical compositions therefrom
GB1514389A (en) Glycerides with antibacterial properties
JPS5225740A (en) Preparation of o-acyl-amidinophenols or acid addition salts thereof
JPS5253897A (en) Process for preparing, n6-etheno-2-subtituted-thio-adenosine-2', 5'pho sphates
IE790872L (en) Piperazine methanimine derivatives
GB1504707A (en) 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydroindoles
JPS5239674A (en) Imidazole derivatives and agricultural bactericides therefrom
GB1299053A (en) Substituted 6-nitroaniline derivatives, processes for their preparation, and their use as herbicidal agents
GB1527941A (en) 1-(3-phenylpropyl)-4-(beta-alkoxyacryloyl)piperazine derivatives
SE412907B (sv) Forfarande for framstellning av nya n-2'-karboxifenyl-4-klorantranilsyror
ATE63544T1 (de) 4-cyanopiperidine-derivate, herstellung und anwendung.
JPS5287174A (en) Preparation of novel 2-amino 1,4-dihydropyridine derivatives
JPS5461185A (en) Nucleic acid base derivatives
JPS5412384A (en) Carbostyril derivative
JPS51123823A (en) A barbituric acid insecticide and tickicide
GB1501588A (en) 4,5-disubstituted 2-oxazolealkanoic acids esters and alkali metal salts