ES2782898T3 - Métodos de administración de compuestos agonistas de la trombopoyetina - Google Patents

Métodos de administración de compuestos agonistas de la trombopoyetina Download PDF

Info

Publication number
ES2782898T3
ES2782898T3 ES16183711T ES16183711T ES2782898T3 ES 2782898 T3 ES2782898 T3 ES 2782898T3 ES 16183711 T ES16183711 T ES 16183711T ES 16183711 T ES16183711 T ES 16183711T ES 2782898 T3 ES2782898 T3 ES 2782898T3
Authority
ES
Spain
Prior art keywords
compound
amount
dose
pharmaceutically acceptable
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES16183711T
Other languages
English (en)
Spanish (es)
Inventor
Connie Erickson-Miller
Julian Jenkins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43223061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2782898(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2782898T3 publication Critical patent/ES2782898T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41521,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES16183711T 2009-05-29 2010-05-27 Métodos de administración de compuestos agonistas de la trombopoyetina Active ES2782898T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18214809P 2009-05-29 2009-05-29

Publications (1)

Publication Number Publication Date
ES2782898T3 true ES2782898T3 (es) 2020-09-16

Family

ID=43223061

Family Applications (2)

Application Number Title Priority Date Filing Date
ES16183711T Active ES2782898T3 (es) 2009-05-29 2010-05-27 Métodos de administración de compuestos agonistas de la trombopoyetina
ES10781176.2T Active ES2605593T3 (es) 2009-05-29 2010-05-27 Métodos de administración de compuestos agonistas de trombopoyetina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES10781176.2T Active ES2605593T3 (es) 2009-05-29 2010-05-27 Métodos de administración de compuestos agonistas de trombopoyetina

Country Status (20)

Country Link
US (1) US8609693B2 (enExample)
EP (2) EP2434894B1 (enExample)
JP (3) JP2012528184A (enExample)
KR (1) KR20120015355A (enExample)
CN (2) CN104173337A (enExample)
AU (1) AU2010254046C1 (enExample)
BR (1) BRPI1014548A2 (enExample)
CA (1) CA2763768A1 (enExample)
DK (1) DK3127427T3 (enExample)
EA (2) EA201690401A1 (enExample)
ES (2) ES2782898T3 (enExample)
HU (1) HUE049075T2 (enExample)
IL (1) IL216365A (enExample)
MX (1) MX2011012668A (enExample)
PL (2) PL3127427T3 (enExample)
PT (2) PT2434894T (enExample)
SG (1) SG176088A1 (enExample)
SI (1) SI3127427T1 (enExample)
WO (1) WO2010138656A1 (enExample)
ZA (1) ZA201108374B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010045310A1 (en) * 2008-10-16 2010-04-22 Glaxosmithkline Llc Method of treating thrombocytopenia
PT2434894T (pt) 2009-05-29 2016-11-29 Novartis Ag Métodos de administração de compostos agonistas de trombopoietina

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE193350C (enExample)
US851444A (en) 1905-11-13 1907-04-23 Agfa Ag Amido-oxy-sulfonic acid of phenylnaphthimidazol and process of making same.
GB779880A (en) 1953-02-27 1957-07-24 Ciba Ltd Functional derivatives of azo-dyestuffs containing sulphonic acid groups and processfor making them
US2809963A (en) 1954-10-26 1957-10-15 Ciba Ltd Azo-dyestuffs
DE1046220B (de) 1956-04-21 1958-12-11 Bayer Ag Verfahren zur Herstellung von Monoazofarbstoffen und deren Metallkomplexverbindungen
GB826207A (en) 1956-07-23 1959-12-31 Bayer Ag ú´-ú´-dihydroxy-monoazo dyestuffs containing pyrrolidonyl residues and their metal complex compounds
US2950273A (en) 1956-11-20 1960-08-23 Agfa Ag Process for the production of symmetrical and unsymmetrical azo compounds
US3366619A (en) 1965-04-09 1968-01-30 Interchem Corp Disazo pyrazolone pigments
US4435417A (en) 1981-02-20 1984-03-06 Gruppo Lepetit S.P.A. Antiinflammatory 3H-naphtho[1,2-d]imidazoles
ES523609A0 (es) 1982-07-05 1985-03-01 Erba Farmitalia Procedimiento para preparar derivados n-imidazolilicos de compuestos biciclicos.
FR2559483B1 (fr) 1984-02-10 1986-12-05 Sandoz Sa Composes heterocycliques contenant des groupes basiques et/ou cationiques, leur preparation et leur utilisation comme colorants
US4582831A (en) 1984-11-16 1986-04-15 Pfizer Inc. Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor
FI91869C (fi) 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
US4880788A (en) 1987-10-30 1989-11-14 Baylor College Of Medicine Method for preventing and treating thrombosis
US5326776A (en) 1992-03-02 1994-07-05 Abbott Laboratories Angiotensin II receptor antagonists
IL109570A0 (en) 1993-05-17 1994-08-26 Fujisawa Pharmaceutical Co Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
EP0638617A1 (de) 1993-08-13 1995-02-15 Ciba-Geigy Ag Pigmentsalze
EP0661170B1 (en) 1993-12-28 1998-09-02 Dai Nippon Printing Co., Ltd. Thermal transfer sheet
US5482546A (en) 1994-03-30 1996-01-09 Canon Kabushiki Kaisha Dye, ink containing the same, and ink-jet recording method and instrument using the ink
TW496870B (en) 1994-03-31 2002-08-01 Amgen Inc Compositions methods for stimulating megakaryocyte growth and differentiation
US5760038A (en) 1995-02-06 1998-06-02 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
US5746821A (en) 1995-02-13 1998-05-05 Engelhard Corporation Pigment compositions
PT885242E (pt) 1995-06-07 2008-06-18 Glaxo Group Ltd Péptidos e compostos que se ligam a um receptor de trombopoietina
US5622818A (en) 1995-11-29 1997-04-22 Eastman Kodak Company Color photographic elements containing yellow colored magenta dye forming masking couplers
US5669967A (en) 1996-05-30 1997-09-23 Engelhard Corporation Pigment compositions
US5932546A (en) 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
SE9701398D0 (sv) 1997-04-15 1997-04-15 Astra Pharma Prod Novel compounds
GB9715830D0 (en) 1997-07-25 1997-10-01 Basf Ag Reactive dyes containing piperazine
WO1999011262A1 (en) 1997-09-02 1999-03-11 Roche Diagnostics Gmbh Mpl-receptor ligands, process for their preparation, medicaments containing them and their use for the treatment and prevention of thrombocytopaenia and anaemia
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
CA2308317A1 (en) 1997-10-31 1999-05-14 Smithkline Beecham Corporation Novel metal complexes
DE19851389A1 (de) 1998-11-07 2000-05-11 Dystar Textilfarben Gmbh & Co Gelbe Farbstoffmischungen von wasserlöslichen faserreaktiven Azofarbstoffen und ihre Verwendung
GC0000177A (en) 1998-12-17 2006-03-29 Smithkline Beecham Thrombopoietin mimetics
CO5210907A1 (es) 1999-05-12 2002-10-30 Novartis Ag Solvatos de pometrozina, insecticidamente activos, composiciones que contienen estos compuestos y metodos tanto para producir dichos compuestos y composiciones como para controlar plagas animales con estas composiciones
KR20020069183A (ko) 1999-07-26 2002-08-29 시오노기세이야쿠가부시키가이샤 트롬보포이에틴 작동성을 나타내는 의약 조성물
WO2001017349A1 (en) 1999-09-10 2001-03-15 Smithkline Beckman Corporation Thrombopoietin mimetics
DE60032783T2 (de) 1999-09-24 2007-12-06 Smithkline Beecham Corp. Thrombopoietinmimetika
AU1462201A (en) 1999-11-05 2001-06-06 Smithkline Beecham Corporation Semicarbazone derivatives and their use as thrombopoietin mimetics
ES2160560T1 (es) 1999-11-10 2001-11-16 Curacyte Ag Colorantes o,o'-dihidroxi-azoicos como constituyentes de medicamentos para el tratamiento de trombopenias.
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US6436915B1 (en) 2000-04-07 2002-08-20 Kinetek Pharmaceuticals, Inc. Pyrazole compounds
HUP0001417A2 (hu) 2000-04-07 2002-12-28 Sanofi-Synthelabo Gyógyászatilag alkalmazható új sók, eljárás előállításukra és azokat tartalmazó gyógyászati készítmények
US6214813B1 (en) 2000-04-07 2001-04-10 Kinetek Pharmaceuticals, Inc. Pyrazole compounds
CY2010012I2 (el) * 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
WO2002049413A2 (en) 2000-12-19 2002-06-27 Smithkline Beecham Corporation Thrombopoietin mimetics
DE60132488D1 (de) 2000-12-21 2008-03-06 Ligand Pharmaceuticals Regulierte aktivierung von zellmembranrezeptoren durch metallchelatisierende agonisten
WO2002059099A1 (en) 2001-01-26 2002-08-01 Shionogi & Co., Ltd. Cyclic compounds having thrombopoietin receptor agonism
CA2435143A1 (en) 2001-01-26 2002-08-01 Shionogi & Co., Ltd. Halogen compounds having thrombopoietin receptor agonism
EP1370252A4 (en) 2001-03-01 2006-04-05 Smithkline Beecham Corp Thrombopoietin mimetics
JP3927001B2 (ja) 2001-06-15 2007-06-06 三菱化学株式会社 色素セット、インクセット並びに記録方法
CN1671379A (zh) 2001-11-30 2005-09-21 Qlt公司 亚肼基吡唑衍生物和它们作为治疗剂的用途
WO2003074550A2 (en) 2002-03-01 2003-09-12 Pintex Pharmaceuticals, Inc. Pin1-modulating compounds and methods of use thereof
TWI280128B (en) 2002-05-22 2007-05-01 Smithkline Beecham Corp 3'-[(2Z)-[1-(3,4- dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid bis-(monoethanolamine)
AU2003248630A1 (en) 2002-06-06 2003-12-22 Smithkline Beecham Corporation Thrombopoietin mimetics
JP4317818B2 (ja) 2002-09-30 2009-08-19 アステラス製薬株式会社 2−アシルアミノチアゾール誘導体の新規な塩
WO2004054515A2 (en) 2002-12-13 2004-07-01 Smithkline Beecham Corporation Thrombopoietin mimetics
JP4895807B2 (ja) 2003-04-29 2012-03-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 変性疾患/損傷の治療方法
TW200526638A (en) 2003-10-22 2005-08-16 Smithkline Beecham Corp 2-(3,4-dimethylphenyl)-4-{[2-hydroxy-3'-(1H-tetrazol-5-yl)biphenyl-3-yl]-hydrazono}-5-methyl-2,4-dihydropyrazol-3-one choline
JP2009508476A (ja) * 2005-08-31 2009-03-05 セントカー・インコーポレーテツド 高められたエフェクター機能をもつ抗体定常領域の製造用の宿主細胞株
US20070202140A1 (en) * 2005-12-22 2007-08-30 Veltri Enrico P Thrombin receptor antagonists as prophylaxis to complications from cardiopulmonary surgery
US20090304634A1 (en) 2006-12-12 2009-12-10 Smithkline Beecham Corporation Novel Combinations
UY30915A1 (es) 2007-02-16 2008-09-02 Smithkline Beecham Corp Método de tratamiento de canceres
ECSP077628A (es) 2007-05-03 2008-12-30 Smithkline Beechman Corp Nueva composición farmacéutica
WO2009151862A1 (en) 2008-05-15 2009-12-17 Smithkline Beecham Corporation Method of treatment
WO2010045310A1 (en) 2008-10-16 2010-04-22 Glaxosmithkline Llc Method of treating thrombocytopenia
EP2427053A4 (en) 2009-05-07 2012-12-05 Glaxosmithkline Llc METHOD FOR TREATING THROMBOCYTOPENIA
PT2434894T (pt) 2009-05-29 2016-11-29 Novartis Ag Métodos de administração de compostos agonistas de trombopoietina
CN111399357A (zh) 2015-04-11 2020-07-10 安田斯研究所有限公司 影像识别方法及记录媒介

Also Published As

Publication number Publication date
CN102458120A (zh) 2012-05-16
SI3127427T1 (sl) 2020-07-31
CN104173337A (zh) 2014-12-03
AU2010254046B2 (en) 2013-10-10
PT3127427T (pt) 2020-04-17
IL216365A (en) 2015-09-24
SG176088A1 (en) 2011-12-29
IL216365A0 (en) 2012-01-31
ES2605593T3 (es) 2017-03-15
JP2016020360A (ja) 2016-02-04
EP2434894B1 (en) 2016-08-31
EP3127427B1 (en) 2020-01-08
WO2010138656A1 (en) 2010-12-02
JP2012528184A (ja) 2012-11-12
MX2011012668A (es) 2011-12-16
US20120064036A1 (en) 2012-03-15
EP2434894A4 (en) 2013-02-20
EP3127427A1 (en) 2017-02-08
EP2434894A1 (en) 2012-04-04
ZA201108374B (en) 2012-07-25
US8609693B2 (en) 2013-12-17
EA201171462A1 (ru) 2012-05-30
DK3127427T3 (da) 2020-04-06
BRPI1014548A2 (pt) 2015-08-25
KR20120015355A (ko) 2012-02-21
AU2010254046C1 (en) 2014-03-06
JP2017226668A (ja) 2017-12-28
PL3127427T3 (pl) 2020-06-15
AU2010254046A1 (en) 2011-12-08
PT2434894T (pt) 2016-11-29
EA201690401A1 (ru) 2016-06-30
EA024557B1 (ru) 2016-09-30
HUE049075T2 (hu) 2020-08-28
PL2434894T3 (pl) 2017-04-28
CA2763768A1 (en) 2010-12-02

Similar Documents

Publication Publication Date Title
RU2356547C2 (ru) Способы лечения рака с использованием ингибиторов hdac
ES2653615T3 (es) Pluralidad de dosis de LAG-3 recombinante para su uso en la provocación de una respuesta inmunitaria de monocitos
EP2635269B1 (en) A combination composition
JP2010526101A5 (enExample)
ES2689760T3 (es) Combinación de bortezomib con afuresertib y uso de la misma en el tratamiento de cáncer
JPS62185017A (ja) 変形性関節症および関連した病気の治療のためのn−アセチルグルコサミンの使用
KR101628448B1 (ko) 암 치료에 사용하기 위한 베무라페닙 및 인터페론을 포함하는 병용 요법
ES2782898T3 (es) Métodos de administración de compuestos agonistas de la trombopoyetina
BR112020007817A2 (pt) método de uso e composições contendo dulaglutido
US20160199350A1 (en) Combination of hdac inhibitors with thrombocytopenia drugs
ES2978336T3 (es) Combinación de un inhibidor de Mcl-1 y midostaurina, usos y composiciones farmacéuticas de la misma
ES2199817T3 (es) Preparacion combinada para tratar la malaria.
ES2975274T3 (es) Combinación de un inhibidor de MCL-1 y un compuesto de taxano, sus usos y composiciones farmacéuticas
ES2761311T3 (es) Tratamiento terapéutico
JP2012526137A (ja) 血小板減少症を治療する方法
CN101181232B (zh) 一种治疗实体肿瘤的马赛替尼缓释植入剂
CN111407748B (zh) 酪醇在制备治疗脑胶质瘤的药物中的应用
KR102273445B1 (ko) 셀레질린을 유효성분으로 포함하는 급성 골수성 백혈병의 예방 또는 치료용 약학 조성물
CN100444836C (zh) 含有丹参素钠的注射组合物
ES2930009T3 (es) Métodos para el cáncer e inmunoterapia con análogos de glutamina, comprendiendo deoxinivalenol DON incluido
RU2236848C1 (ru) Средство, уменьшающее токсичность противоопухолевых препаратов
WO2021196335A1 (zh) Pyr3的用途
HK1193771B (en) Therapeutic treatment