ES2390761T3 - Anticuerpos recombinantes de alta potencia y método para producción de los mismos - Google Patents

Anticuerpos recombinantes de alta potencia y método para producción de los mismos Download PDF

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Publication number
ES2390761T3
ES2390761T3 ES01914657T ES01914657T ES2390761T3 ES 2390761 T3 ES2390761 T3 ES 2390761T3 ES 01914657 T ES01914657 T ES 01914657T ES 01914657 T ES01914657 T ES 01914657T ES 2390761 T3 ES2390761 T3 ES 2390761T3
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Prior art keywords
antibody
seq
antibodies
amino acid
kon
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Expired - Lifetime
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ES01914657T
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English (en)
Spanish (es)
Inventor
James F. Young
Scott Koenig
Leslie S. Johnson
William D. Huse
Herren Wu
Jeffry D. Watkins
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MedImmune LLC
Applied Molecular Evolution Inc
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MedImmune LLC
Applied Molecular Evolution Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/11—Paramyxoviridae (F); Pneumoviridae (F), e.g. respiratory syncytial virus [RSV]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES01914657T 2000-03-01 2001-03-01 Anticuerpos recombinantes de alta potencia y método para producción de los mismos Expired - Lifetime ES2390761T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18625200P 2000-03-01 2000-03-01
US186252P 2000-03-01
PCT/US2001/006815 WO2001064751A2 (en) 2000-03-01 2001-03-01 High potency recombinant antibodies and method for producing them

Publications (1)

Publication Number Publication Date
ES2390761T3 true ES2390761T3 (es) 2012-11-16

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Family Applications (1)

Application Number Title Priority Date Filing Date
ES01914657T Expired - Lifetime ES2390761T3 (es) 2000-03-01 2001-03-01 Anticuerpos recombinantes de alta potencia y método para producción de los mismos

Country Status (10)

Country Link
US (2) US7700735B2 (https=)
EP (3) EP2341075A1 (https=)
JP (2) JP2003525061A (https=)
AU (4) AU2001240020B9 (https=)
CA (1) CA2401652A1 (https=)
CY (1) CY1113298T1 (https=)
DK (1) DK1259547T3 (https=)
ES (1) ES2390761T3 (https=)
PT (1) PT1259547E (https=)
WO (1) WO2001064751A2 (https=)

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US7700735B2 (en) 2010-04-20
US20100239574A1 (en) 2010-09-23
AU2001240020B2 (en) 2007-02-08
US8153133B2 (en) 2012-04-10
AU4002001A (en) 2001-09-12
AU2007202040A1 (en) 2007-05-24
EP1259547B1 (en) 2012-07-11
EP2341074A1 (en) 2011-07-06
CA2401652A1 (en) 2001-09-07
JP2003525061A (ja) 2003-08-26
WO2001064751A3 (en) 2001-12-20
EP1259547A2 (en) 2002-11-27
EP2341075A1 (en) 2011-07-06
US20020098189A1 (en) 2002-07-25
CY1113298T1 (el) 2016-04-13
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AU2007202040B2 (en) 2010-06-10
AU2010219289B2 (en) 2012-05-10
WO2001064751A2 (en) 2001-09-07
PT1259547E (pt) 2012-10-15
JP2010162025A (ja) 2010-07-29
AU2001240020B9 (en) 2008-12-04

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