AU2001238079A1 - Antibody gene therapy with adeno-associated viral vectors - Google Patents
Antibody gene therapy with adeno-associated viral vectorsInfo
- Publication number
- AU2001238079A1 AU2001238079A1 AU2001238079A AU3807901A AU2001238079A1 AU 2001238079 A1 AU2001238079 A1 AU 2001238079A1 AU 2001238079 A AU2001238079 A AU 2001238079A AU 3807901 A AU3807901 A AU 3807901A AU 2001238079 A1 AU2001238079 A1 AU 2001238079A1
- Authority
- AU
- Australia
- Prior art keywords
- adeno
- gene therapy
- viral vectors
- antibody gene
- associated viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000001415 gene therapy Methods 0.000 title 1
- 239000013603 viral vector Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18231200P | 2000-02-09 | 2000-02-09 | |
US60182312 | 2000-02-09 | ||
PCT/US2001/004150 WO2001059142A1 (en) | 2000-02-09 | 2001-02-09 | Antibody gene therapy with adeno-associated viral vectors |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001238079A1 true AU2001238079A1 (en) | 2001-08-20 |
Family
ID=22667908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001238079A Abandoned AU2001238079A1 (en) | 2000-02-09 | 2001-02-09 | Antibody gene therapy with adeno-associated viral vectors |
Country Status (3)
Country | Link |
---|---|
US (1) | US20010034062A1 (en) |
AU (1) | AU2001238079A1 (en) |
WO (1) | WO2001059142A1 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040136914A1 (en) | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
JP4992068B2 (en) | 2000-01-27 | 2012-08-08 | メディミューン,エルエルシー | Ultra high affinity neutralizing antibody |
EP1259547B1 (en) * | 2000-03-01 | 2012-07-11 | Medimmune, Inc. | High potency recombinant antibodies and method for producing them |
US6855493B2 (en) * | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
US7179900B2 (en) | 2000-11-28 | 2007-02-20 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
US20030198624A1 (en) * | 2002-03-02 | 2003-10-23 | Mohapatra Shyam S. | Method of treating allergic disease and asthma by recombinant adenovirus- and adeno-associated virus- mediated IFN-gamma gene transfer |
AU2003223517A1 (en) * | 2002-04-09 | 2003-10-27 | Children's Hospital, Inc. | Antibody gene transfer and recombinant aav |
US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
AU2003232081B2 (en) * | 2002-07-03 | 2009-02-05 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
KR100858080B1 (en) * | 2002-11-12 | 2008-09-10 | 삼성전자주식회사 | A method for detecting a PCR product by measuring a electrical signal |
EP1812068A4 (en) * | 2004-10-29 | 2010-06-09 | Medimmune Inc | Methods of preventing and treating rsv infections and related conditions |
EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
JP6261617B2 (en) | 2013-02-14 | 2018-01-17 | ユーシーエル ビジネス ピーエルシー | Agents that induce lymphangiogenesis used in the treatment of cystic kidney disease |
CN111479916A (en) | 2017-10-20 | 2020-07-31 | 弗莱德哈钦森癌症研究中心 | Systems and methods for generating B cells genetically modified to express selected antibodies |
CA3086045A1 (en) | 2017-12-19 | 2019-06-27 | Akouos, Inc. | Aav-mediated delivery of therapeutic antibodies to the inner ear |
AU2018394940A1 (en) * | 2017-12-29 | 2020-08-13 | Cornell University | Gene therapy for eosinohilic disorders |
US20240148903A1 (en) * | 2021-03-08 | 2024-05-09 | Nanjing GenScript Biotech Co., Ltd. | Delivery of antibody by using dual viral vector system |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
WO1996037234A1 (en) * | 1995-05-23 | 1996-11-28 | Thomas Jefferson University | Intracellular immunization |
JP3948495B2 (en) * | 1995-08-24 | 2007-07-25 | ジェネーラ コーポレーション | Asthma-related factors as targets for treating atopic allergies, including asthma and related diseases |
CA2251738A1 (en) * | 1996-04-16 | 1997-10-23 | Immusol Incorporated | Targeted viral vectors |
US6590079B2 (en) * | 1997-01-30 | 2003-07-08 | Ixsys, Incorporated | Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same |
PT1064393E (en) * | 1998-03-20 | 2005-04-29 | Univ Pennsylvania | COMPOSITIONS AND METHODS FOR THE PRODUCTION OF RECOMBINANT ADENO-ASSOCIATED VIRUSES WITHOUT AUXILIARY |
-
2001
- 2001-02-09 WO PCT/US2001/004150 patent/WO2001059142A1/en active Application Filing
- 2001-02-09 US US09/781,052 patent/US20010034062A1/en not_active Abandoned
- 2001-02-09 AU AU2001238079A patent/AU2001238079A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20010034062A1 (en) | 2001-10-25 |
WO2001059142A1 (en) | 2001-08-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001238079A1 (en) | Antibody gene therapy with adeno-associated viral vectors | |
AU2001265187A1 (en) | Chimeric viral vectors for gene therapy | |
AU2002248297A1 (en) | Aav2 vectors and methods | |
AU2001236073A1 (en) | Gene recombinant antibody and its fragment | |
AU2002226050A1 (en) | Microtiter plate with integral heater | |
AU4903101A (en) | Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof | |
AU1951201A (en) | Peptide antigens | |
AU2001257532A1 (en) | Adenoviral vectors for tumor specific gene expression and uses thereof | |
AU2001229494A1 (en) | Chimeric prostate-homing peptides with pro-apoptotic activity | |
AU2003223517A1 (en) | Antibody gene transfer and recombinant aav | |
AU2001280576A1 (en) | Tissue-specific self-inactivating gene therapy vector | |
AU2002349543A1 (en) | Tumor antigens | |
AU2002251871A1 (en) | Muscle-directed gene therapy with aav-1 and aav-6 vectors | |
AU2002250078A1 (en) | Quantitative epstein barr virus pcr rapid assay | |
AUPR546801A0 (en) | Recombinant antibodies | |
AU2001246703A1 (en) | Dna immunization vectors | |
AU2002347813A1 (en) | Chimeric viral vectors for gene therapy | |
AU2001242625A1 (en) | Gene sequence | |
AU2001288839A1 (en) | Self-rearranging dna vectors | |
AU2001259169A1 (en) | Cesert genes, proteins, and modulatory compounds | |
AU2001294325A1 (en) | Hulahoop fixed the winged finger-pressure projection | |
AU2001227570A1 (en) | Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof | |
AU2001234150A1 (en) | Novel protein and gene encoding the same | |
AU6181500A (en) | Gene encoding novel tsp1-like protein | |
AU2001274563A1 (en) | Novel polypeptide and its dna |