ES2378090T3 - Clústeres de genes biosintéticos lantibióticos a partir de A. garbadinensis y A. liguriae - Google Patents

Clústeres de genes biosintéticos lantibióticos a partir de A. garbadinensis y A. liguriae Download PDF

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Publication number
ES2378090T3
ES2378090T3 ES07704921T ES07704921T ES2378090T3 ES 2378090 T3 ES2378090 T3 ES 2378090T3 ES 07704921 T ES07704921 T ES 07704921T ES 07704921 T ES07704921 T ES 07704921T ES 2378090 T3 ES2378090 T3 ES 2378090T3
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ES
Spain
Prior art keywords
actagardin
compound
seq
polypeptide
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07704921T
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English (en)
Spanish (es)
Inventor
Steven Boakes
Jesus Cortes Bargallo
Michael John Dawson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novacta Biosystems Ltd
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Novacta Biosystems Ltd
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Publication date
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES07704921T 2006-01-17 2007-01-17 Clústeres de genes biosintéticos lantibióticos a partir de A. garbadinensis y A. liguriae Active ES2378090T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0600928 2006-01-17
GBGB0600928.6A GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics
PCT/GB2007/000138 WO2007083112A2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae

Publications (1)

Publication Number Publication Date
ES2378090T3 true ES2378090T3 (es) 2012-04-04

Family

ID=35998187

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07704921T Active ES2378090T3 (es) 2006-01-17 2007-01-17 Clústeres de genes biosintéticos lantibióticos a partir de A. garbadinensis y A. liguriae

Country Status (20)

Country Link
US (3) US7989416B2 (https=)
EP (2) EP2189472A1 (https=)
JP (1) JP5219837B2 (https=)
KR (1) KR101573536B1 (https=)
CN (1) CN101389641B (https=)
AT (1) ATE534659T1 (https=)
AU (1) AU2007206769B2 (https=)
BR (1) BRPI0706525A2 (https=)
CA (1) CA2637315A1 (https=)
CY (1) CY1112559T1 (https=)
DK (1) DK1979375T3 (https=)
ES (1) ES2378090T3 (https=)
GB (1) GB0600928D0 (https=)
IL (1) IL192446A0 (https=)
MX (1) MX2008009047A (https=)
NZ (1) NZ569486A (https=)
PL (1) PL1979375T3 (https=)
PT (1) PT1979375E (https=)
SI (1) SI1979375T1 (https=)
WO (1) WO2007083112A2 (https=)

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GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714030D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
GB0900599D0 (en) 2009-01-14 2009-02-18 Novacta Biosystems Ltd Treatment
SI2387580T1 (sl) * 2009-01-14 2014-11-28 Novacta Biosystems Limited Deoksiaktagardinski derivati
MX2011008043A (es) * 2009-02-04 2011-08-17 Novacta Biosystems Ltd Derivados de actagardina.
JP5852966B2 (ja) * 2010-02-02 2016-02-03 ノヴァクタ バイオシステムズ リミティッド ランチビオティックの塩
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
US20130171252A1 (en) 2010-07-14 2013-07-04 Novacta Biosystems Limited Formulation Comprising a Type B Lantibiotic
GB201013509D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013508D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013507D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) * 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
EP2925342A4 (en) 2012-11-30 2016-07-06 Naicons Srl NOVEL LANTIBIOTIC DERIVATIVES AND PREPARATION METHOD THEREOF
CN103483433B (zh) * 2013-09-10 2015-05-27 中国科学院微生物研究所 一种新型高效的羊毛硫细菌素cerecidin及其应用
CN106188253B (zh) * 2016-08-26 2020-08-18 上海交通大学 抗菌肽Lexapeptide及其制备方法和用途
CN113777306A (zh) * 2020-06-09 2021-12-10 首都医科大学附属北京世纪坛医院 尿液果糖二磷酸醛缩酶b及其多肽片段在烧伤中的应用
CN115637247B (zh) * 2021-07-20 2026-02-24 中国科学院微生物研究所 生物氧化脱硫的盐单胞菌工程菌株及其全细胞催化脱硫方法

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DE19745583A1 (de) * 1997-10-15 1999-04-22 Hoechst Marion Roussel De Gmbh Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben
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JP2009509519A (ja) 2005-09-27 2009-03-12 ノヴァクタ バイオシステムズ リミティッド ランチビオティックメルサシジンの変種およびそれらの使用
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
KR20120038021A (ko) 2006-10-27 2012-04-20 화이자 프로덕츠 인코포레이티드 하이드록시프로필 메틸 셀룰로스 경질 캡슐 및 이의 제조 방법
CA2690267A1 (en) 2007-06-12 2008-12-18 The University Of British Columbia Small cationic antimicrobial peptides
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
GB0714030D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
WO2010058238A1 (en) 2008-11-24 2010-05-27 Sentinella Pharmaceuticals, Inc. ("Sentinella") Lantibiotic carboxyamide derivatives with enhanced antibacterial activity
SI2387580T1 (sl) 2009-01-14 2014-11-28 Novacta Biosystems Limited Deoksiaktagardinski derivati
GB0900599D0 (en) 2009-01-14 2009-02-18 Novacta Biosystems Ltd Treatment
MX2011008043A (es) 2009-02-04 2011-08-17 Novacta Biosystems Ltd Derivados de actagardina.
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Also Published As

Publication number Publication date
MX2008009047A (es) 2008-12-18
JP5219837B2 (ja) 2013-06-26
AU2007206769B2 (en) 2013-06-20
CN101389641B (zh) 2013-06-05
KR101573536B1 (ko) 2015-12-11
CA2637315A1 (en) 2007-07-26
DK1979375T3 (da) 2012-03-19
WO2007083112A3 (en) 2008-05-08
EP1979375B1 (en) 2011-11-23
US7989416B2 (en) 2011-08-02
USRE45003E1 (en) 2014-07-08
JP2009523777A (ja) 2009-06-25
IL192446A0 (en) 2008-12-29
WO2007083112A2 (en) 2007-07-26
PL1979375T3 (pl) 2012-04-30
AU2007206769A1 (en) 2007-07-26
EP1979375A2 (en) 2008-10-15
GB0600928D0 (en) 2006-02-22
US20100048459A1 (en) 2010-02-25
NZ569486A (en) 2011-07-29
EP1979375B9 (en) 2012-05-09
EP2189472A1 (en) 2010-05-26
PT1979375E (pt) 2012-03-06
CN101389641A (zh) 2009-03-18
CY1112559T1 (el) 2016-02-10
US20110306091A1 (en) 2011-12-15
BRPI0706525A2 (pt) 2011-03-29
US8465947B2 (en) 2013-06-18
KR20080086517A (ko) 2008-09-25
ATE534659T1 (de) 2011-12-15
SI1979375T1 (sl) 2012-03-30

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