IT1260505B - Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon - Google Patents

Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon

Info

Publication number
IT1260505B
IT1260505B ITMI921347A ITMI921347A IT1260505B IT 1260505 B IT1260505 B IT 1260505B IT MI921347 A ITMI921347 A IT MI921347A IT MI921347 A ITMI921347 A IT MI921347A IT 1260505 B IT1260505 B IT 1260505B
Authority
IT
Italy
Prior art keywords
colon
pharmaceutical systems
oral pharmaceutical
specific release
delayed delivery
Prior art date
Application number
ITMI921347A
Other languages
English (en)
Inventor
Stefano Poli
Luigi Moro
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11363431&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1260505(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Priority to ITMI921347A priority Critical patent/IT1260505B/it
Publication of ITMI921347A0 publication Critical patent/ITMI921347A0/it
Priority to HU9301577A priority patent/HUT75158A/hu
Priority to DK93108658T priority patent/DK0572942T4/da
Priority to ES93108658T priority patent/ES2101164T5/es
Priority to EP93108658A priority patent/EP0572942B2/en
Priority to DE69309540T priority patent/DE69309540T3/de
Priority to AT93108658T priority patent/ATE151285T1/de
Publication of ITMI921347A1 publication Critical patent/ITMI921347A1/it
Publication of IT1260505B publication Critical patent/IT1260505B/it
Application granted granted Critical
Priority to GR970401249T priority patent/GR3023605T3/el
Priority to GR20010400245T priority patent/GR3035415T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Vengono descritti dei nuovi sistemi farmaceutici, per uso orale, in grado di rilasciare il componente attivo in siti specifici del tratto digerente in virtù di un meccanismo tempo-attivato. Il colon costituisce un sito preferenziale di rilascio.Il sistema è costituito da un nucleo in grado di cedere l'attivo che contiene grazie alla modulazione indotta da uno o due strati di differente solubilità o contenuto tecnologico.
ITMI921347A 1992-06-01 1992-06-01 Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon IT1260505B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI921347A IT1260505B (it) 1992-06-01 1992-06-01 Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon
AT93108658T ATE151285T1 (de) 1992-06-01 1993-05-28 Orale arzneimittel mit kolonspezifischer freisetzung
ES93108658T ES2101164T5 (es) 1992-06-01 1993-05-28 Composiciones farmaceuticas orales para el suministro especifico al colon.
DK93108658T DK0572942T4 (da) 1992-06-01 1993-05-28 Orale farmaceutiske præparater til specifik frigivelse i kolon
HU9301577A HUT75158A (en) 1992-06-01 1993-05-28 Oral pharmaceutical compositions for selective release of drug in the colon, and process for producing them
EP93108658A EP0572942B2 (en) 1992-06-01 1993-05-28 Oral pharmaceutical compositions for specific colon delivery
DE69309540T DE69309540T3 (de) 1992-06-01 1993-05-28 Orale Arzneimittel mit kolonspezifischer Freisetzung
GR970401249T GR3023605T3 (en) 1992-06-01 1997-05-30 Oral pharmaceutical compositions for specific colon delivery
GR20010400245T GR3035415T3 (en) 1992-06-01 2001-02-14 Oral pharmaceutical compositions for specific colon delivery.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921347A IT1260505B (it) 1992-06-01 1992-06-01 Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon

Publications (3)

Publication Number Publication Date
ITMI921347A0 ITMI921347A0 (it) 1992-06-01
ITMI921347A1 ITMI921347A1 (it) 1993-12-01
IT1260505B true IT1260505B (it) 1996-04-09

Family

ID=11363431

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921347A IT1260505B (it) 1992-06-01 1992-06-01 Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon

Country Status (8)

Country Link
EP (1) EP0572942B2 (it)
AT (1) ATE151285T1 (it)
DE (1) DE69309540T3 (it)
DK (1) DK0572942T4 (it)
ES (1) ES2101164T5 (it)
GR (2) GR3023605T3 (it)
HU (1) HUT75158A (it)
IT (1) IT1260505B (it)

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US6764697B1 (en) 1991-06-27 2004-07-20 Alza Corporation System for delaying drug delivery up to seven hours
US5686105A (en) * 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
US5436011A (en) * 1993-04-16 1995-07-25 Bristol-Myers Squibb Company Solid pharmaceutical dosage form and a method for reducing abrasion
ES2068762B1 (es) * 1993-07-21 1995-12-01 Lipotec Sa Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion.
US5482718A (en) * 1994-03-23 1996-01-09 Hoffmann-La Roche Inc. Colon-targeted delivery system
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
GB9620709D0 (en) * 1996-10-04 1996-11-20 Danbiosyst Uk Colonic delivery of weak acid drugs
US5788987A (en) * 1997-01-29 1998-08-04 Poli Industria Chimica Spa Methods for treating early morning pathologies
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
NL1009107C2 (nl) 1997-11-12 1999-06-15 Banner Pharmacaps Inc Gelatine-uitspreidende doos met meervoudige, aanpasbare poortklep en meerlagig zacht gel.
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
UA74141C2 (uk) 1998-12-09 2005-11-15 Дж.Д. Сірл Енд Ко. Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти)
DE69939335D1 (de) 1998-12-30 2008-09-25 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
MXPA03008292A (es) 2001-03-13 2003-12-11 Penwest Pharmaceuticals Co Formas de dosificacion cronoterapeuticas que contienen glucocorticosteroides.
FR2830446B1 (fr) * 2001-10-09 2004-02-06 Univ Pasteur Composition pharmaceutique destinee a liberer une substance active au niveau du colon
CA2501324A1 (en) * 2002-10-30 2004-05-21 Pharmacia Corporation Oral extended release tablets and methods of making and using the same
CU23334A1 (es) * 2003-03-20 2008-12-24 Inst Finlay Vacuna de vibrio cholerae inactivada en tabletas
CA2539051C (en) 2003-09-19 2014-08-12 Penwest Pharmaceuticals Co. Delayed release dosage forms
GB2411355B (en) 2004-02-27 2006-02-22 Niche Generics Ltd Pharmaceutical composition
ITMI20041295A1 (it) 2004-06-25 2004-09-25 Cosmo Spa Composizioni farmaceutiche antimicrobiche orali
EP1754471A1 (de) * 2005-08-18 2007-02-21 ORAMON-Arzneimittel GmbH & Co. KG Verwendung einer quellbaren Zwischenschicht zur Steuerung des Freisetzungsprofils einer festen Arzneimittelformulierung zur peroralen Anwendung und diese enthaltende Arzneimittelformulierung
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714030D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
US20110117142A1 (en) * 2008-07-02 2011-05-19 Basf Se Method for coating tablets
IT1393244B1 (it) 2008-07-18 2012-04-12 Universita' Degli Studi Di Milano Sistema per il rilascio al colon di farmaci suscettibili di degradazione enzimatica e/o scarsamente assorbiti nel tratto gastrointestinale
JP5719312B2 (ja) 2009-01-14 2015-05-13 ノヴァクタ バイオシステムズ リミティッド デオキシアクタガルジン誘導体
BRPI1007884A2 (pt) 2009-02-04 2016-09-06 Novacta Biosystems Ltd derivados de actagardina
WO2015161139A1 (en) 2014-04-16 2015-10-22 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
WO2012013495A1 (en) 2010-07-29 2012-02-02 Cosmo Technologies Ltd. Pharmaceutical and/or dietary compositions based on short chain fatty acids
GB201013513D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
WO2013003697A1 (en) 2011-06-30 2013-01-03 Trustees Of Boston University Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
MX2015014060A (es) 2013-04-05 2016-04-07 Polichem Sa Uso de pidotimod para tratar sindrome de intestino irritable.
CA2933908C (en) 2013-12-31 2024-01-30 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
CN105943505A (zh) * 2016-05-26 2016-09-21 杭州百诚医药科技股份有限公司 一种匹多莫德药物组合物及其制备方法
CA3148226A1 (en) 2019-08-12 2021-02-18 Massachusetts Institute Of Technology Articles and methods for administration of therapeutic agents

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US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
US5032406A (en) † 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
PH27186A (en) * 1989-09-07 1993-04-16 Ciba Geigy Ag Double-coated granules of disodium pamidronate
DK469989D0 (da) † 1989-09-22 1989-09-22 Bukh Meditec Farmaceutisk praeparat
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon

Also Published As

Publication number Publication date
ES2101164T5 (es) 2001-02-01
DK0572942T4 (da) 2001-01-22
GR3035415T3 (en) 2001-05-31
EP0572942A3 (en) 1994-08-24
EP0572942A2 (en) 1993-12-08
EP0572942B1 (en) 1997-04-09
ITMI921347A0 (it) 1992-06-01
HU9301577D0 (en) 1993-09-28
DE69309540T3 (de) 2001-03-15
DK0572942T3 (da) 1997-10-20
ES2101164T3 (es) 1997-07-01
DE69309540D1 (de) 1997-05-15
ITMI921347A1 (it) 1993-12-01
ATE151285T1 (de) 1997-04-15
HUT75158A (en) 1997-04-28
GR3023605T3 (en) 1997-08-29
EP0572942B2 (en) 2000-11-29
DE69309540T2 (de) 1997-09-04

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970626