BRPI0606119B8 - preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis - Google Patents

preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis

Info

Publication number
BRPI0606119B8
BRPI0606119B8 BRPI0606119A BRPI0606119A BRPI0606119B8 BR PI0606119 B8 BRPI0606119 B8 BR PI0606119B8 BR PI0606119 A BRPI0606119 A BR PI0606119A BR PI0606119 A BRPI0606119 A BR PI0606119A BR PI0606119 B8 BRPI0606119 B8 BR PI0606119B8
Authority
BR
Brazil
Prior art keywords
diclofenac
injectable preparations
pharmaceutically acceptable
water
acceptable salts
Prior art date
Application number
BRPI0606119A
Other languages
English (en)
Inventor
Rajnibhai Ketan Patel
Rajnibhai Milan Patel
Original Assignee
Troikaa Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36953757&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0606119(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Troikaa Pharmaceuticals Ltd filed Critical Troikaa Pharmaceuticals Ltd
Publication of BRPI0606119A2 publication Critical patent/BRPI0606119A2/pt
Publication of BRPI0606119B1 publication Critical patent/BRPI0606119B1/pt
Publication of BRPI0606119B8 publication Critical patent/BRPI0606119B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis. a presente invenção fornece formulações injetáveis de sais de diclofenaco solúveis em água em doses únicas ou menores do que 2 ml, que causam significativamente menos dor no local da injeção e podem ser administradas via intradeltôlde, em adição a via intraglútea e intravenosa lenta. mais especificamente as preparações injetáveis contém 75 mg a 100 mg de sais de diclofenaco solúveis em água, em cerca de 1 ml de solução de injeção sem elevar significativamente a viscosidade da solução de injeção sem o uso de surfactantes. as formulações são ajustadas em ph 6 a 10 contendo até 100 mg de sal de diclofenaco em um meio compreendido de água, junto com um ou mais cosolvente(s)/solubilizante(s), antioxidantes, conservantes, buffers, álcali e estabilizantes.
BRPI0606119A 2005-02-01 2006-01-30 preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis BRPI0606119B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN96/MUM/2005 2005-02-01
IN96MU2005 2005-02-01
PCT/IN2006/000033 WO2006095363A2 (en) 2005-02-01 2006-01-30 Injectable preparations of diclofenic and its pharmaceutically acceptable salts

Publications (3)

Publication Number Publication Date
BRPI0606119A2 BRPI0606119A2 (pt) 2009-06-02
BRPI0606119B1 BRPI0606119B1 (pt) 2019-05-07
BRPI0606119B8 true BRPI0606119B8 (pt) 2021-05-25

Family

ID=36953757

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0606119A BRPI0606119B8 (pt) 2005-02-01 2006-01-30 preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis

Country Status (20)

Country Link
US (1) US8809393B2 (pt)
EP (1) EP1848419B1 (pt)
JP (1) JP2008528572A (pt)
KR (1) KR101226121B1 (pt)
CN (1) CN101123957B (pt)
AP (1) AP2888A (pt)
AU (2) AU2006221633B2 (pt)
BR (1) BRPI0606119B8 (pt)
CA (1) CA2596031C (pt)
DK (1) DK1848419T3 (pt)
EA (1) EA013616B1 (pt)
ES (1) ES2392097T3 (pt)
IL (1) IL184697A (pt)
MX (1) MX2007009312A (pt)
NZ (1) NZ554779A (pt)
PL (1) PL1848419T3 (pt)
PT (1) PT1848419E (pt)
UA (1) UA93365C2 (pt)
WO (1) WO2006095363A2 (pt)
ZA (1) ZA200705729B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009155315A (ja) * 2007-12-26 2009-07-16 Fujiyakuhin Co Ltd 注射剤
WO2013005226A1 (en) * 2011-07-04 2013-01-10 Zota Health Care Ltd A novel combined pharmaceutical composition containing diclofenac and methods of making and using the same
US20140187635A1 (en) 2012-12-28 2014-07-03 Themis Medicare Limited Diclofenac compositions
US20140275261A1 (en) 2013-03-15 2014-09-18 Dr. Reddy's Laboratories, Inc. Diclofenac parenteral compositions
CN103432132B (zh) * 2013-08-31 2015-01-21 西南大学 甲磺酸普立地诺双氯芬酸钠注射液及其制备方法
WO2016170401A1 (en) * 2015-04-20 2016-10-27 Umedica Laboratories Pvt. Ltd Novel injectable composition of diclofenac sodium
US20220280463A1 (en) 2019-09-09 2022-09-08 Ftf Pharma Private Limited Pharmaceutical formulations comprising diclofenac

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8200488L (sv) 1982-01-29 1983-07-30 Svenska Flaektfabriken Ab Arreteringsanordning, serskilt for forankring av till- och franluftventiler i ventilationskanaler
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
DE3446873A1 (de) * 1984-12-21 1986-07-10 Merckle Gmbh Fluessige diclofenac-zubereitungen
DE3613799C1 (de) * 1986-04-24 1987-09-03 Nattermann A & Cie Verwendung von Glycofurol zum Verfluessigen von Arzneimittelzubereitungen fuer das Abfuellen in Weichgelatinekapseln
EP0532546B1 (en) * 1990-05-10 1998-03-18 Bechgaard International Research And Development A/S A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
US5389681A (en) * 1992-10-22 1995-02-14 Ciba-Geigy Corporation Parenteral solutions for diclofenac salts
ZA949182B (en) * 1993-12-02 1995-07-26 South African Druggists Ltd Pharmaceutical composition
US5554650A (en) 1994-07-28 1996-09-10 Southern Research Institute Antiphlogistic, analgesic, antipyretic injection preparation
GB9502695D0 (en) 1995-02-11 1995-03-29 Glaxo Spa Pharmaceutical composition
US5747058A (en) * 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
BR9709939A (pt) * 1996-06-25 1999-08-10 Glaxo Group Ltd Combinação formulação farmacêutica processo de tratamento de uma infecção por hiv em um animal infectado usos de éster tetraidro-3-furanila do ácido 3s[3r*(1r*,2s*)]-[-3-[[4-amino-fenil)sulfonil](2-metilprop ril)-amino]-2-hidroxi-1-fenilmetil)propil]-carbâmico de zidovudina e de (2r,cis)-4-amino-1-(2-hidroximetil-1,3-oxatiolan-5-il)-(1h)-pirimidin-2-ona e pacote para paciente
US5853263A (en) * 1996-08-15 1998-12-29 Accrued, Inc. System for installing raised road markers
US6846495B2 (en) * 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
DE10105576C1 (de) * 2001-02-07 2002-08-08 Underberg Kg Flasche mit im Boden ausgebildeten Griffmulden
IN192711B (pt) 2002-01-22 2004-05-15 Ketan Rajnibhai Patel
CH694034A8 (de) * 2002-12-12 2004-08-31 Mepha Ag Diclofenac-Kalium-Injektionsloesung.
JP2006514119A (ja) * 2003-02-12 2006-04-27 アール アンド ピー コリア カンパニー リミテッド 溶解率が向上した難溶性薬剤の溶媒系
KR100612070B1 (ko) * 2003-02-12 2006-08-11 알앤피코리아주식회사 용출률이 향상된 난용성 약제의 용매 시스템 및 이를 함유한 제약학적 제제
CN1557290A (zh) 2004-01-19 2004-12-29 江苏扬子江药业集团有限公司 复方双氯芬酸钾注射液制剂
PL1767219T3 (pl) 2004-03-10 2010-06-30 Shimoda Biotech Pty Ltd Trwałe kompozycje diklofenaku do iniekcji
CN1279897C (zh) 2004-04-30 2006-10-18 济南百诺医药科技开发有限公司 含有双氯芬酸盐和利多卡因的冻干制剂及其制备方法
ITMI20041245A1 (it) 2004-06-22 2004-09-22 Ibsa Inst Biochimique Sa Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina

Also Published As

Publication number Publication date
EA013616B1 (ru) 2010-06-30
IL184697A0 (en) 2007-12-03
KR20070107091A (ko) 2007-11-06
CN101123957A (zh) 2008-02-13
PL1848419T3 (pl) 2012-12-31
ZA200705729B (en) 2008-08-27
ES2392097T3 (es) 2012-12-04
NZ554779A (en) 2011-02-25
CA2596031A1 (en) 2006-09-14
IL184697A (en) 2014-02-27
CN101123957B (zh) 2010-12-08
EP1848419A2 (en) 2007-10-31
AP2007004101A0 (en) 2007-08-31
JP2008528572A (ja) 2008-07-31
AU2006221633B2 (en) 2009-07-30
BRPI0606119A2 (pt) 2009-06-02
DK1848419T3 (da) 2012-11-05
PT1848419E (pt) 2012-10-31
WO2006095363A3 (en) 2006-12-14
WO2006095363A2 (en) 2006-09-14
WO2006095363B1 (en) 2007-02-01
BRPI0606119B1 (pt) 2019-05-07
EA200701645A1 (ru) 2008-02-28
US8809393B2 (en) 2014-08-19
MX2007009312A (es) 2008-03-10
AU2006221633A1 (en) 2006-09-14
CA2596031C (en) 2013-02-19
AU2009233594A1 (en) 2009-11-19
KR101226121B1 (ko) 2013-01-25
AP2888A (en) 2014-05-31
UA93365C2 (ru) 2011-02-10
US20080153914A1 (en) 2008-06-26
EP1848419B1 (en) 2012-07-25

Similar Documents

Publication Publication Date Title
BRPI0606119B8 (pt) preparações injetáveis de diclofenaco e seus sais farmaceuticamente aceitáveis
CY1122516T1 (el) Ετοιμες προς χρηση διατυπωσεις κετορολακης
BRPI0418270A (pt) métodos de tratamento e de controle, de tratamento ou prevenção, de controle de um distúrbio do sistema nervoso central, e para reduzir ou evitar um efeito adverso, e, composição farmacêutica
PE20060002A1 (es) Combinaciones antineoplasicas de cci-779 y rituximab
AR043863A1 (es) Composiciones que contienen piperacilina y tazobactam, utiles para inyeccioines
CO6160321A2 (es) Uso de 2-6-(3-amino-piperidin-1-il)-3-metil-2,4-dioxo-3,4-dihidro-2h-pirimidin-1-ilmetil-4-fluoro-benzonitrilo
PE20020127A1 (es) Interleuquina 2 estabilizada
MX2010004549A (es) Composiciones y métodos bacteriostáticos o bactericidas.
AR042977A1 (es) Formulaciones farmaceuticas liquidas de palonosetron
PE20050822A1 (es) Derivados de florfenicol con mejor solubilidad en agua
BRPI0415953A (pt) formulação de dosagem de liberação controlada oral, método de tratamento de um distúrbio, conjunto de formas de dosagem de liberação controlada e método para administração da formulação
BR0012082A (pt) Formulação farmacêutica para administração compreendendo morfina e seu uso
AR078224A1 (es) Composicon para el tratamiento del cancer de prostata
ES2720954T3 (es) Formulaciones estabilizadas de estatina
BRPI9915480B8 (pt) azalídeos de 13 membros, composições farmacêuticas compreendendo os mesmos, método para sua preparação bem como seus usos.
WO2007056263A3 (en) Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously
AR034370A1 (es) Una preparacion farmaceutica acuosa de cilostazol para uso parenteral
BRPI0408136A (pt) derivados heterocìclicos contendo nitrogênio tendo estirila 2,6-dissubstituìda
BR0116060A (pt) Composição farmacêutica de dronedarona para administração parenteral
AR036321A1 (es) Metodo y formulacion farmaceutica para el tratamiento de la discinesia de aparicion tardia.
TN2010000008A1 (en) Oral pharmaceutical solutions containing telbivudine
CO6331430A2 (es) Composicion farmaceutica que comprende la combinacion de una sal de ketorolaco y vitaminas del complejo b para el tratamiento de la neuralgia
GT199900171A (es) Concentrado oral de sertralina.
BRPI0503734A (pt) composição farmacêutica na forma de solução injetável de morfina pronta para uso e forma de dosagem unitária de morfina para administração epidural ou intratecal
ATE302010T1 (de) Pharmazeutische zusammensetzung, enthaltend desoxypeganin zur behandlung des alkoholismus

Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: TROIKAA PHARMACEUTICALS LTD. (IN)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 016080000660/RS DE 30/01/2008.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/05/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/05/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/01/2006 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 18A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2759 DE 21-11-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.