NO910213L - Fremgangsmaate for fremstilling av orale legemiddelformer av pimobendan. - Google Patents

Fremgangsmaate for fremstilling av orale legemiddelformer av pimobendan.

Info

Publication number
NO910213L
NO910213L NO91910213A NO910213A NO910213L NO 910213 L NO910213 L NO 910213L NO 91910213 A NO91910213 A NO 91910213A NO 910213 A NO910213 A NO 910213A NO 910213 L NO910213 L NO 910213L
Authority
NO
Norway
Prior art keywords
pimobendan
procedure
preparation
oral pharmaceutical
pharmaceutical forms
Prior art date
Application number
NO91910213A
Other languages
English (en)
Other versions
NO176305C (no
NO176305B (no
NO910213D0 (no
Inventor
Peter Gruber
Willy Roth
Gottfried Schepky
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO910213D0 publication Critical patent/NO910213D0/no
Publication of NO910213L publication Critical patent/NO910213L/no
Publication of NO176305B publication Critical patent/NO176305B/no
Publication of NO176305C publication Critical patent/NO176305C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO910213A 1990-01-20 1991-01-18 Fremgangsmåte for fremstilling av orale legemiddelformer av pimobendan NO176305C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4001622A DE4001622A1 (de) 1990-01-20 1990-01-20 Orale arzneimittelformen von pimobendan

Publications (4)

Publication Number Publication Date
NO910213D0 NO910213D0 (no) 1991-01-18
NO910213L true NO910213L (no) 1991-07-22
NO176305B NO176305B (no) 1994-12-05
NO176305C NO176305C (no) 1995-03-15

Family

ID=6398467

Family Applications (1)

Application Number Title Priority Date Filing Date
NO910213A NO176305C (no) 1990-01-20 1991-01-18 Fremgangsmåte for fremstilling av orale legemiddelformer av pimobendan

Country Status (18)

Country Link
EP (1) EP0439030B1 (no)
JP (1) JP2608183B2 (no)
KR (1) KR0163056B1 (no)
AT (1) ATE87481T1 (no)
AU (1) AU630536B2 (no)
CA (1) CA2034569C (no)
DE (2) DE4001622A1 (no)
DK (1) DK0439030T3 (no)
ES (1) ES2054379T3 (no)
FI (1) FI96274C (no)
HK (1) HK175796A (no)
HU (1) HU207948B (no)
IE (1) IE64659B1 (no)
IL (1) IL96995A (no)
NO (1) NO176305C (no)
NZ (1) NZ236834A (no)
PT (1) PT96506B (no)
ZA (1) ZA91372B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753904B1 (fr) * 1996-10-01 1998-10-30 Gattefosse Ets Sa Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication
DE102004011512B4 (de) * 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
WO2005107719A2 (en) * 2004-05-06 2005-11-17 Sandoz Ag Pharmaceutical composition comprising hydrophobic drug having improved solubility
WO2005123040A1 (ja) * 2004-06-22 2005-12-29 Shionogi & Co., Ltd. 口腔内速崩壊錠
JP4572296B2 (ja) * 2004-07-21 2010-11-04 トーアエイヨー株式会社 ピモベンダン経口投与製剤
JP2006028130A (ja) * 2004-07-21 2006-02-02 Toa Eiyo Ltd ピモベンダン経口投与製剤
JP4572293B2 (ja) * 2004-07-21 2010-11-04 トーアエイヨー株式会社 ピモベンダン経口投与製剤
EP1937270A1 (en) * 2005-09-21 2008-07-02 Brystol-Myers Squibb Company Oral administration of n-(2-chloro-6-methylphenyl)-2-[[6-4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-1,3-thiazole-5-carboxamide and salts thereof
JP4572300B2 (ja) * 2006-01-19 2010-11-04 トーアエイヨー株式会社 ピモベンダン経口投与製剤
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
PE20081482A1 (es) * 2006-12-20 2008-12-23 Novartis Ag Capsulas de gelatina que contienen un acido
FR2934156B1 (fr) 2008-07-23 2010-09-24 Virbac Medicament appetissant a administration orale sous forme solide
WO2010055119A2 (en) * 2008-11-17 2010-05-20 Novartis Ag Pharmaceutical composition comprising pimobendan
PT2370070E (pt) 2008-11-25 2013-11-18 Boehringer Ingelheim Vetmed Utilização de pimobendano para o tratamento da cardiomiopatia hipertrófica felina
NL1037569C2 (en) 2009-12-18 2011-06-21 Eurovet Animal Health B V Crystalline pimobendan, process for the preparation thereof, pharmaceutical composition and use.
JPWO2011081117A1 (ja) * 2009-12-29 2013-05-09 興和株式会社 経口投与用固形医薬組成物
CN102711763A (zh) * 2009-12-29 2012-10-03 兴和株式会社 口服用医药组合物
ES2924478T3 (es) 2012-03-15 2022-10-07 Boehringer Ingelheim Vetmedica Gmbh Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos
CN113181110A (zh) 2013-07-19 2021-07-30 勃林格殷格翰动物保健有限公司 含有防腐的醚化的环糊精衍生物的液体水性药物组合物
WO2015082389A1 (en) 2013-12-04 2015-06-11 Boehringer Ingelheim Vetmedica Gmbh Improved pharmaceutical compositions of pimobendan
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
CN106729723A (zh) * 2016-11-21 2017-05-31 青岛农业大学 一种含匹莫苯丹的药物组合物及其制备方法
WO2024126434A1 (en) 2022-12-15 2024-06-20 Boehringer Ingelheim Vetmedica Gmbh Solid dispersions comprising amorphous pimobendan and one or more stabilizing polymers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2837161A1 (de) * 1978-08-25 1980-03-06 Thomae Gmbh Dr K Neue benzimidazole und deren verwendung
ES8101067A1 (es) * 1978-08-25 1980-12-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
JPS56110612A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Readily disintegrable and absorbable compression molded article of slightly soluble drug
JPS60163823A (ja) * 1984-02-03 1985-08-26 Taisho Pharmaceut Co Ltd 経口投与製剤
DE3776269D1 (de) * 1986-11-03 1992-03-05 Schering Corp Labetalol tablette mit verzoegerter wirkstoffabgabe.
DE3728244A1 (de) * 1987-08-25 1989-03-09 Thomae Gmbh Dr K Neue (-)-benzimidazole, deren herstellung und diese verbindungen enthaltende arzneimittel
EP0306846A3 (de) * 1987-09-11 1990-05-02 Dr. Karl Thomae GmbH Neue synergistische Kombination bestehend aus einem Phosphodiesterase-Hemmer und einem Thromboxan-A2-Antagonisten und deren Verwendung bzw. Herstellung
DE3805635A1 (de) * 1988-02-24 1989-09-07 Thomae Gmbh Dr K Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit ss-blockern oder bradycardica
JPH01258621A (ja) * 1988-04-06 1989-10-16 Fujimoto Seiyaku Kk 吸収が調節されたジラゼプ錠
JPH023609A (ja) * 1988-06-21 1990-01-09 Fujimoto Seiyaku Kk 塩酸ニカルジピンを活性成分とする持効性製剤

Also Published As

Publication number Publication date
FI96274B (fi) 1996-02-29
ATE87481T1 (de) 1993-04-15
KR910014120A (ko) 1991-08-31
DE4001622A1 (de) 1991-07-25
EP0439030A2 (de) 1991-07-31
ES2054379T3 (es) 1994-08-01
HU207948B (en) 1993-07-28
HUT56494A (en) 1991-09-30
HU910177D0 (en) 1991-08-28
CA2034569C (en) 2002-03-19
JPH04210919A (ja) 1992-08-03
AU630536B2 (en) 1992-10-29
IE910165A1 (en) 1991-07-31
IE64659B1 (en) 1995-08-23
NO176305C (no) 1995-03-15
JP2608183B2 (ja) 1997-05-07
DE59100067D1 (de) 1993-05-06
FI96274C (fi) 1996-06-10
EP0439030B1 (de) 1993-03-31
FI910263A0 (fi) 1991-01-18
IL96995A (en) 1994-11-11
PT96506A (pt) 1991-10-15
NO176305B (no) 1994-12-05
ZA91372B (en) 1992-09-30
EP0439030A3 (en) 1991-10-16
AU6945491A (en) 1991-07-25
DK0439030T3 (da) 1993-08-16
NO910213D0 (no) 1991-01-18
NZ236834A (en) 1995-10-26
PT96506B (pt) 1998-06-30
CA2034569A1 (en) 1991-07-21
IL96995A0 (en) 1992-03-29
HK175796A (en) 1996-09-27
KR0163056B1 (ko) 1998-12-01
FI910263A (fi) 1991-07-21

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