ES2054379T3 - Formas farmaceuticas orales de pimobendano. - Google Patents
Formas farmaceuticas orales de pimobendano.Info
- Publication number
- ES2054379T3 ES2054379T3 ES91100309T ES91100309T ES2054379T3 ES 2054379 T3 ES2054379 T3 ES 2054379T3 ES 91100309 T ES91100309 T ES 91100309T ES 91100309 T ES91100309 T ES 91100309T ES 2054379 T3 ES2054379 T3 ES 2054379T3
- Authority
- ES
- Spain
- Prior art keywords
- pimobendano
- oral pharmaceutical
- pharmaceutical forms
- pimobendan
- variations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LOS TIPOS DE MEDICAMENTOS ADMINISTRADOS ORALMENTE DE PIMOBENDAN QUE CONTIENEN ACIDO CITRICO, GARANTIZAN UNA BUENA REABSORCION UNIFORME, INCLUSO AL PRESENTARSE FUERTES OSCILACIONES DE PH EN LA PARTE GASTROINTESTINAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4001622A DE4001622A1 (de) | 1990-01-20 | 1990-01-20 | Orale arzneimittelformen von pimobendan |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2054379T3 true ES2054379T3 (es) | 1994-08-01 |
Family
ID=6398467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91100309T Expired - Lifetime ES2054379T3 (es) | 1990-01-20 | 1991-01-11 | Formas farmaceuticas orales de pimobendano. |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0439030B1 (es) |
JP (1) | JP2608183B2 (es) |
KR (1) | KR0163056B1 (es) |
AT (1) | ATE87481T1 (es) |
AU (1) | AU630536B2 (es) |
CA (1) | CA2034569C (es) |
DE (2) | DE4001622A1 (es) |
DK (1) | DK0439030T3 (es) |
ES (1) | ES2054379T3 (es) |
FI (1) | FI96274C (es) |
HK (1) | HK175796A (es) |
HU (1) | HU207948B (es) |
IE (1) | IE64659B1 (es) |
IL (1) | IL96995A (es) |
NO (1) | NO176305C (es) |
NZ (1) | NZ236834A (es) |
PT (1) | PT96506B (es) |
ZA (1) | ZA91372B (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2753904B1 (fr) * | 1996-10-01 | 1998-10-30 | Gattefosse Ets Sa | Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication |
DE102004011512B4 (de) * | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
WO2005107719A2 (en) * | 2004-05-06 | 2005-11-17 | Sandoz Ag | Pharmaceutical composition comprising hydrophobic drug having improved solubility |
WO2005123040A1 (ja) * | 2004-06-22 | 2005-12-29 | Shionogi & Co., Ltd. | 口腔内速崩壊錠 |
JP4572296B2 (ja) * | 2004-07-21 | 2010-11-04 | トーアエイヨー株式会社 | ピモベンダン経口投与製剤 |
JP2006028130A (ja) * | 2004-07-21 | 2006-02-02 | Toa Eiyo Ltd | ピモベンダン経口投与製剤 |
JP4572293B2 (ja) * | 2004-07-21 | 2010-11-04 | トーアエイヨー株式会社 | ピモベンダン経口投与製剤 |
EP1937270A1 (en) * | 2005-09-21 | 2008-07-02 | Brystol-Myers Squibb Company | Oral administration of n-(2-chloro-6-methylphenyl)-2-[[6-4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-1,3-thiazole-5-carboxamide and salts thereof |
JP4572300B2 (ja) * | 2006-01-19 | 2010-11-04 | トーアエイヨー株式会社 | ピモベンダン経口投与製剤 |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
PE20081482A1 (es) * | 2006-12-20 | 2008-12-23 | Novartis Ag | Capsulas de gelatina que contienen un acido |
FR2934156B1 (fr) | 2008-07-23 | 2010-09-24 | Virbac | Medicament appetissant a administration orale sous forme solide |
WO2010055119A2 (en) * | 2008-11-17 | 2010-05-20 | Novartis Ag | Pharmaceutical composition comprising pimobendan |
PT2370070E (pt) | 2008-11-25 | 2013-11-18 | Boehringer Ingelheim Vetmed | Utilização de pimobendano para o tratamento da cardiomiopatia hipertrófica felina |
NL1037569C2 (en) | 2009-12-18 | 2011-06-21 | Eurovet Animal Health B V | Crystalline pimobendan, process for the preparation thereof, pharmaceutical composition and use. |
JPWO2011081117A1 (ja) * | 2009-12-29 | 2013-05-09 | 興和株式会社 | 経口投与用固形医薬組成物 |
CN102711763A (zh) * | 2009-12-29 | 2012-10-03 | 兴和株式会社 | 口服用医药组合物 |
ES2924478T3 (es) | 2012-03-15 | 2022-10-07 | Boehringer Ingelheim Vetmedica Gmbh | Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos |
CN113181110A (zh) | 2013-07-19 | 2021-07-30 | 勃林格殷格翰动物保健有限公司 | 含有防腐的醚化的环糊精衍生物的液体水性药物组合物 |
WO2015082389A1 (en) | 2013-12-04 | 2015-06-11 | Boehringer Ingelheim Vetmedica Gmbh | Improved pharmaceutical compositions of pimobendan |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
CN106729723A (zh) * | 2016-11-21 | 2017-05-31 | 青岛农业大学 | 一种含匹莫苯丹的药物组合物及其制备方法 |
WO2024126434A1 (en) | 2022-12-15 | 2024-06-20 | Boehringer Ingelheim Vetmedica Gmbh | Solid dispersions comprising amorphous pimobendan and one or more stabilizing polymers |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2837161A1 (de) * | 1978-08-25 | 1980-03-06 | Thomae Gmbh Dr K | Neue benzimidazole und deren verwendung |
ES8101067A1 (es) * | 1978-08-25 | 1980-12-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona |
JPS56110612A (en) * | 1980-02-08 | 1981-09-01 | Yamanouchi Pharmaceut Co Ltd | Readily disintegrable and absorbable compression molded article of slightly soluble drug |
JPS60163823A (ja) * | 1984-02-03 | 1985-08-26 | Taisho Pharmaceut Co Ltd | 経口投与製剤 |
DE3776269D1 (de) * | 1986-11-03 | 1992-03-05 | Schering Corp | Labetalol tablette mit verzoegerter wirkstoffabgabe. |
DE3728244A1 (de) * | 1987-08-25 | 1989-03-09 | Thomae Gmbh Dr K | Neue (-)-benzimidazole, deren herstellung und diese verbindungen enthaltende arzneimittel |
EP0306846A3 (de) * | 1987-09-11 | 1990-05-02 | Dr. Karl Thomae GmbH | Neue synergistische Kombination bestehend aus einem Phosphodiesterase-Hemmer und einem Thromboxan-A2-Antagonisten und deren Verwendung bzw. Herstellung |
DE3805635A1 (de) * | 1988-02-24 | 1989-09-07 | Thomae Gmbh Dr K | Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit ss-blockern oder bradycardica |
JPH01258621A (ja) * | 1988-04-06 | 1989-10-16 | Fujimoto Seiyaku Kk | 吸収が調節されたジラゼプ錠 |
JPH023609A (ja) * | 1988-06-21 | 1990-01-09 | Fujimoto Seiyaku Kk | 塩酸ニカルジピンを活性成分とする持効性製剤 |
-
1990
- 1990-01-20 DE DE4001622A patent/DE4001622A1/de not_active Withdrawn
-
1991
- 1991-01-11 AT AT91100309T patent/ATE87481T1/de not_active IP Right Cessation
- 1991-01-11 EP EP91100309A patent/EP0439030B1/de not_active Expired - Lifetime
- 1991-01-11 DK DK91100309.3T patent/DK0439030T3/da active
- 1991-01-11 ES ES91100309T patent/ES2054379T3/es not_active Expired - Lifetime
- 1991-01-11 DE DE9191100309T patent/DE59100067D1/de not_active Expired - Lifetime
- 1991-01-17 PT PT96506A patent/PT96506B/pt not_active IP Right Cessation
- 1991-01-18 CA CA002034569A patent/CA2034569C/en not_active Expired - Lifetime
- 1991-01-18 HU HU91177A patent/HU207948B/hu unknown
- 1991-01-18 ZA ZA91372A patent/ZA91372B/xx unknown
- 1991-01-18 FI FI910263A patent/FI96274C/fi active
- 1991-01-18 NZ NZ236834A patent/NZ236834A/en unknown
- 1991-01-18 AU AU69454/91A patent/AU630536B2/en not_active Expired
- 1991-01-18 KR KR1019910000822A patent/KR0163056B1/ko not_active IP Right Cessation
- 1991-01-18 JP JP3004069A patent/JP2608183B2/ja not_active Expired - Lifetime
- 1991-01-18 NO NO910213A patent/NO176305C/no not_active IP Right Cessation
- 1991-01-18 IE IE16591A patent/IE64659B1/en not_active IP Right Cessation
- 1991-01-22 IL IL9699591A patent/IL96995A/en not_active IP Right Cessation
-
1996
- 1996-09-19 HK HK175796A patent/HK175796A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI96274B (fi) | 1996-02-29 |
ATE87481T1 (de) | 1993-04-15 |
KR910014120A (ko) | 1991-08-31 |
DE4001622A1 (de) | 1991-07-25 |
EP0439030A2 (de) | 1991-07-31 |
HU207948B (en) | 1993-07-28 |
HUT56494A (en) | 1991-09-30 |
HU910177D0 (en) | 1991-08-28 |
CA2034569C (en) | 2002-03-19 |
JPH04210919A (ja) | 1992-08-03 |
AU630536B2 (en) | 1992-10-29 |
IE910165A1 (en) | 1991-07-31 |
IE64659B1 (en) | 1995-08-23 |
NO176305C (no) | 1995-03-15 |
JP2608183B2 (ja) | 1997-05-07 |
DE59100067D1 (de) | 1993-05-06 |
FI96274C (fi) | 1996-06-10 |
EP0439030B1 (de) | 1993-03-31 |
FI910263A0 (fi) | 1991-01-18 |
IL96995A (en) | 1994-11-11 |
PT96506A (pt) | 1991-10-15 |
NO176305B (no) | 1994-12-05 |
ZA91372B (en) | 1992-09-30 |
EP0439030A3 (en) | 1991-10-16 |
AU6945491A (en) | 1991-07-25 |
DK0439030T3 (da) | 1993-08-16 |
NO910213D0 (no) | 1991-01-18 |
NO910213L (no) | 1991-07-22 |
NZ236834A (en) | 1995-10-26 |
PT96506B (pt) | 1998-06-30 |
CA2034569A1 (en) | 1991-07-21 |
IL96995A0 (en) | 1992-03-29 |
HK175796A (en) | 1996-09-27 |
KR0163056B1 (ko) | 1998-12-01 |
FI910263A (fi) | 1991-07-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2054379T3 (es) | Formas farmaceuticas orales de pimobendano. | |
ITBO910024A1 (it) | Formulazioni farmaceutiche contenenti glicosaminoglicani assorbibili per via orale. | |
DK0667148T3 (da) | Peroralt farmaceutisk præparat, der udløses i den nedre del af mavetarmkanalen | |
NO912607D0 (no) | Oral, fast farmasoeytisk doseringsform med programmert frigivelse. | |
NO20053106D0 (no) | Oral, analgesisk doseringsform med forlenget frigivelse. | |
DE69101931D1 (de) | Pharmazeutische Zusammensetzung. | |
DE69104777D1 (de) | Orale Arzneimittelformen von biologisch aktiven Eiweisstoffen. | |
DZ1876A1 (fr) | Médicaments pour administration orale. | |
DE3679920D1 (de) | Spiro-3-heteroazolidinverbindungen und ihre salze, ihre herstellung und diese enthaltende pharmazeutische mittel. | |
NO911429L (no) | Stoffbehandling. | |
NO913897D0 (no) | Legemiddelemballasje med kappelukke. | |
DE3578597D1 (de) | 4-phenylphthalazin-derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. | |
DE3681856D1 (de) | Pharmazeutische 2-oxopyrrolidinverbindungen, ihre salze und ihre herstellung. | |
NO911430L (no) | Stoffbehandlingsmetode. | |
FI923371A0 (fi) | En farmaceutisk formulation. | |
ATE145333T1 (de) | Hirudin enthaltende orale arzneimittel | |
ATE165239T1 (de) | Orale arzeimittelzubereitung enthaltend diclofenac-natrium und eine organische säure | |
IT9048244A0 (it) | Composizione farmaceutica ad effetto cicatrizzante. | |
DE3887237D1 (de) | Arzneimittel. | |
ES1018109Y (es) | Chupete tentetieso. | |
DE69111530D1 (de) | Pyridincarbonsäure-Amid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen. | |
ATE78405T1 (de) | Pharmazeutische zusammensetzung, enthaltend piperidinalkanolderivate. | |
IS4288A (is) | 2,4-dísúlfónýlfenýlbútýlnítrón, sölt þess, lyfjablanda ásamt notkun á þessu efnasambandi við framleiðslu á lyfi | |
MX9206975A (es) | Composicion farmaceutica. | |
ATE65695T1 (de) | Pharmazeutische zusammensetzungen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 439030 Country of ref document: ES |