ATE38151T1 - Bestaendige 5-adenosyl-l-methionin-salze enthaltende, pharmazeutische zusammensetzungen fuer orale anwendung. - Google Patents

Bestaendige 5-adenosyl-l-methionin-salze enthaltende, pharmazeutische zusammensetzungen fuer orale anwendung.

Info

Publication number
ATE38151T1
ATE38151T1 AT84109110T AT84109110T ATE38151T1 AT E38151 T1 ATE38151 T1 AT E38151T1 AT 84109110 T AT84109110 T AT 84109110T AT 84109110 T AT84109110 T AT 84109110T AT E38151 T1 ATE38151 T1 AT E38151T1
Authority
AT
Austria
Prior art keywords
oral use
adenosyl
pharmaceutical compositions
compositions containing
salts
Prior art date
Application number
AT84109110T
Other languages
English (en)
Inventor
Federico Gennari
Pier Luigi Aspesi
Original Assignee
Bioresearch Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Spa filed Critical Bioresearch Spa
Application granted granted Critical
Publication of ATE38151T1 publication Critical patent/ATE38151T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
AT84109110T 1983-08-24 1984-08-01 Bestaendige 5-adenosyl-l-methionin-salze enthaltende, pharmazeutische zusammensetzungen fuer orale anwendung. ATE38151T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22621/83A IT1169772B (it) 1983-08-24 1983-08-24 Composizioni terapeutiche per uso orale contenenti sali stabili della s-adenosil-l-metionina
EP84109110A EP0136464B1 (de) 1983-08-24 1984-08-01 Beständige 5-Adenosyl-L-Methionin-Salze enthaltende, pharmazeutische Zusammensetzungen für orale Anwendung

Publications (1)

Publication Number Publication Date
ATE38151T1 true ATE38151T1 (de) 1988-11-15

Family

ID=11198524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84109110T ATE38151T1 (de) 1983-08-24 1984-08-01 Bestaendige 5-adenosyl-l-methionin-salze enthaltende, pharmazeutische zusammensetzungen fuer orale anwendung.

Country Status (7)

Country Link
EP (1) EP0136464B1 (de)
JP (1) JPS6072815A (de)
AT (1) ATE38151T1 (de)
AU (1) AU563762B2 (de)
CA (1) CA1224418A (de)
DE (1) DE3474774D1 (de)
IT (1) IT1169772B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0212745B1 (de) * 1985-08-16 1991-04-10 The Procter & Gamble Company Partikel mit konstanter Wirkstofffreisetzung
DE3678644D1 (de) * 1985-08-16 1991-05-16 Procter & Gamble Wirkstoffpartikel mit sowohl kontinuierlicher als auch schneller freisetzung.
DE3678643D1 (de) * 1985-08-16 1991-05-16 Procter & Gamble Partikel mit konstanter wirkstofffreisetzung.
WO1988002629A1 (en) * 1986-10-16 1988-04-21 American Health Products Corporation 2',3'-didesoxyadenosine composition
GB8900812D0 (en) * 1989-01-14 1989-03-08 Univ Manchester Pharmaceutical method and compositions
IT1229479B (it) * 1989-03-13 1991-09-03 Bioresearch Spa Impiego di 5' deossi 5' metiltioadenosina, di s adenosilmetionina e dei loro sali per la preparazione di composizioni farmaceutiche atte a favorire la crescita dei capelli in soggetti affetti da calvizie e composizioni farmaceutiche relative.
US6759395B2 (en) 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
WO2002049637A1 (en) * 2000-12-18 2002-06-27 Orchid Chemicals And Pharmaceuticals Limited A novel soft-gelatin capsule comprising s-adenosylmethionine and a method for producing the same
DK1325740T3 (da) * 2001-12-12 2004-08-16 Chemistry & Health Int Bv Stabile granulater indeholdende s-adenosylmethionin og fremgangsmåde til fremstilling deraf
US20080206333A1 (en) * 2007-01-31 2008-08-28 Methylation Sciences International Srl Extended Release Pharmaceutical Formulations of S-Adenosylmethionine
EP2193787A1 (de) 2008-12-02 2010-06-09 Giorgio Stramentinoli Formulierungen zur systemischen bukkalen Abgabe, die S-Adenosylmethionin umfassen, deren Herstellung und Verwendung
US8329208B2 (en) 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
EA015508B1 (ru) * 2011-03-03 2011-08-30 Екофарм Патент Менеджмент Аг Фармацевтическая композиция, стимулирующая биосинтез s-аденозилметионина, и пероральное лекарственное средство

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
JPS5347536A (en) * 1976-10-12 1978-04-28 Abbott Lab Pharmaceutical composition for treatment of fertile skin disease
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Also Published As

Publication number Publication date
EP0136464A2 (de) 1985-04-10
JPS6072815A (ja) 1985-04-24
IT8322621A0 (it) 1983-08-24
AU563762B2 (en) 1987-07-23
CA1224418A (en) 1987-07-21
IT1169772B (it) 1987-06-03
DE3474774D1 (en) 1988-12-01
JPH0531524B2 (de) 1993-05-12
EP0136464A3 (en) 1985-07-03
EP0136464B1 (de) 1988-10-26
AU3232684A (en) 1985-02-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee