IT1137892B - Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo - Google Patents

Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Info

Publication number
IT1137892B
IT1137892B IT23603/81A IT2360381A IT1137892B IT 1137892 B IT1137892 B IT 1137892B IT 23603/81 A IT23603/81 A IT 23603/81A IT 2360381 A IT2360381 A IT 2360381A IT 1137892 B IT1137892 B IT 1137892B
Authority
IT
Italy
Prior art keywords
adenosylmethionine
preparation
active principle
therapeutic compositions
stable salts
Prior art date
Application number
IT23603/81A
Other languages
English (en)
Other versions
IT8123603A0 (it
Inventor
Federico Gennari
Original Assignee
Bioresearch Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11208488&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1137892(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioresearch Srl filed Critical Bioresearch Srl
Priority to IT23603/81A priority Critical patent/IT1137892B/it
Publication of IT8123603A0 publication Critical patent/IT8123603A0/it
Priority to AT82107333T priority patent/ATE16394T1/de
Priority to EP82107333A priority patent/EP0073376B2/en
Priority to DE8282107333T priority patent/DE3267295D1/de
Priority to US06/408,682 priority patent/US4543408A/en
Priority to ZA825971A priority patent/ZA825971B/xx
Priority to IL66584A priority patent/IL66584A0/xx
Priority to AU87405/82A priority patent/AU552466B2/en
Priority to CA000409945A priority patent/CA1201434A/en
Priority to NO822863A priority patent/NO153370C/no
Priority to CS826142A priority patent/CZ279834B6/cs
Priority to ES515191A priority patent/ES8306371A1/es
Priority to DK377282A priority patent/DK149861C/da
Priority to AR290387A priority patent/AR231453A1/es
Priority to GR69091A priority patent/GR76862B/el
Priority to PT75454A priority patent/PT75454B/pt
Priority to PL1982238024A priority patent/PL137816B1/pl
Priority to JP57145582A priority patent/JPS5843995A/ja
Priority to FI822944A priority patent/FI72525C/fi
Priority to HU822725A priority patent/HU186108B/hu
Priority to NZ201679A priority patent/NZ201679A/en
Priority to DD82242759A priority patent/DD210455A1/de
Priority to MX698782A priority patent/MX154896A/es
Priority to YU1908/82A priority patent/YU42793B/xx
Publication of IT1137892B publication Critical patent/IT1137892B/it
Application granted granted Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
IT23603/81A 1981-08-24 1981-08-24 Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo IT1137892B (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT23603/81A IT1137892B (it) 1981-08-24 1981-08-24 Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
AT82107333T ATE16394T1 (de) 1981-08-24 1982-08-12 Stabile salze von s-adenosinylmethionin, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen welche als aktive substanz diese derivate enthalten.
EP82107333A EP0073376B2 (en) 1981-08-24 1982-08-12 Stable s-adenosylmethionine salts, the process for their preparation and therapeutic compositions which contain them as active principle
DE8282107333T DE3267295D1 (en) 1981-08-24 1982-08-12 Stable s-adenosylmethionine salts, the process for their preparation and therapeutic compositions which contain them as active principle
US06/408,682 US4543408A (en) 1981-08-24 1982-08-16 Stable S-adenosylmethionine salts, the process for their preparation, and therapeutic compositions which contain them as active principle
ZA825971A ZA825971B (en) 1981-08-24 1982-08-17 Stable s-adenosylmethionine salts the process for their preparation and therapeutic compositions which contain them as active principle
IL66584A IL66584A0 (en) 1981-08-24 1982-08-19 Stable s-adenosylmethionine salts,their preparation and pharmaceutical compositions containing them
AU87405/82A AU552466B2 (en) 1981-08-24 1982-08-19 Stable s-adenosylmethionine salts
PT75454A PT75454B (en) 1981-08-24 1982-08-23 Process for the preparation of stable s-adenosylmethionine salts
ES515191A ES8306371A1 (es) 1981-08-24 1982-08-23 "un procedimiento para la preparacion de sales de s-adenosilmetionina".
NO822863A NO153370C (no) 1981-08-24 1982-08-23 Analogifremgangsmaate ved fremstilling av terapeutisk aktive, stabile s-adenosylmethionisalter.
CS826142A CZ279834B6 (cs) 1981-08-24 1982-08-23 Stálé soli S-adenosylmethioninu a způsob jejich výroby
CA000409945A CA1201434A (en) 1981-08-24 1982-08-23 S-adenosylmethionine derivatives, the process for their preparation, and therapeutic compositions which contain them as active principle
DK377282A DK149861C (da) 1981-08-24 1982-08-23 Analogifremgangsmaade til fremstilling af s-adenosyl-methioninsalte
AR290387A AR231453A1 (es) 1981-08-24 1982-08-23 Procedimiento para la preparacion de sales de s-adenosilmetionina que tienen elevada estabilidad
GR69091A GR76862B (it) 1981-08-24 1982-08-23
YU1908/82A YU42793B (en) 1981-08-24 1982-08-24 Process for obtaining s-adenosly methionine salts
JP57145582A JPS5843995A (ja) 1981-08-24 1982-08-24 安定なｓ−アデノシルメチオニン塩、それらの製造法及び活性成分としてこれらを含む治療組成物
PL1982238024A PL137816B1 (en) 1981-08-24 1982-08-24 Method of obtaining stable delta-adenozilomethionine salts
FI822944A FI72525C (fi) 1981-08-24 1982-08-24 Foerfarande foer framstaellning av terapeutiskt anvaendbara stabila s-adenocylmetioninsalter.
HU822725A HU186108B (en) 1981-08-24 1982-08-24 Process for producing stabile s-adenosylmethionine
NZ201679A NZ201679A (en) 1981-08-24 1982-08-24 S-adenosylmethionine salts,a process for their preparation and pharmaceutical compositions which contain them
DD82242759A DD210455A1 (de) 1981-08-24 1982-08-24 Verfahren zur herstellung der salze von s-adenosilmehtionin
MX698782A MX154896A (es) 1981-08-24 1982-08-24 Procedimiento para la preparacion de sales de s-adenosil-metionina estables

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23603/81A IT1137892B (it) 1981-08-24 1981-08-24 Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Publications (2)

Publication Number Publication Date
IT8123603A0 IT8123603A0 (it) 1981-08-24
IT1137892B true IT1137892B (it) 1986-09-10

Family

ID=11208488

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23603/81A IT1137892B (it) 1981-08-24 1981-08-24 Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo

Country Status (23)

Country Link
US (1) US4543408A (it)
EP (1) EP0073376B2 (it)
JP (1) JPS5843995A (it)
AR (1) AR231453A1 (it)
AT (1) ATE16394T1 (it)
AU (1) AU552466B2 (it)
CA (1) CA1201434A (it)
CZ (1) CZ279834B6 (it)
DD (1) DD210455A1 (it)
DE (1) DE3267295D1 (it)
DK (1) DK149861C (it)
ES (1) ES8306371A1 (it)
FI (1) FI72525C (it)
GR (1) GR76862B (it)
HU (1) HU186108B (it)
IL (1) IL66584A0 (it)
IT (1) IT1137892B (it)
NO (1) NO153370C (it)
NZ (1) NZ201679A (it)
PL (1) PL137816B1 (it)
PT (1) PT75454B (it)
YU (1) YU42793B (it)
ZA (1) ZA825971B (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1169772B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Composizioni terapeutiche per uso orale contenenti sali stabili della s-adenosil-l-metionina
IT1169774B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina
IT1169773B (it) * 1983-08-24 1987-06-03 Bioresearch Spa Processo per la produzione di sali stabili della solfo-adenosil-l-metionina
JPS6279792A (ja) * 1985-10-04 1987-04-13 Showa Sangyo Kk 注射用原料結晶ぶどう糖の製造方法
FR2623396B1 (fr) * 1987-11-25 1990-03-30 Sanofi Sa Utilisation de l'ademetionine contre le vieillissement de la peau
US6492349B1 (en) 1993-03-31 2002-12-10 Nutramax Laboratories, Inc. Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
IT1317920B1 (it) * 2000-10-20 2003-07-15 Univ Roma S-adenosilmetionina e suoi derivati per il trattamento e laprevenzione della malattia di alzheimer.
US6649753B2 (en) 2001-06-07 2003-11-18 Orchid Chemicals & Pharmaceuticals Ltd. Stable salts of S-adenosyl-L-methionine (SAMe) and the process for their preparation
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
US9080158B2 (en) 2006-05-16 2015-07-14 Mitsubishi Gas Chemical Company, Inc. Method of producing S-adenosyl-L-methionine-containing dry yeast having excellent storage stability, the product thereof and composition for oral intake
CA2675970C (en) 2007-01-25 2016-01-05 Mitsubishi Gas Chemical Company, Inc. Method for production of dry yeast containing s-adenosyl-l-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
ITMI20071374A1 (it) * 2007-07-10 2009-01-11 Gnosis Spa Sali stabili di s-adenosilmetionina e processo per il loro ottenimento.
US20100004191A1 (en) * 2008-07-01 2010-01-07 Rolland F Hebert Compositions of S-adenosyl-L-methionine.
CN101481660B (zh) * 2009-01-20 2011-02-09 中国药科大学 一株高产腺苷蛋氨酸的菌种
EP2945959B1 (en) 2013-01-16 2020-05-13 Hebert Sam-E LLC Stable indole-3-propionate salts of s-adenosyl-l-methionine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969353A (en) * 1957-02-06 1961-01-24 Merck & Co Inc Process for the preparation of "active methionine" and products obtained thereby
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
JPS5320998B2 (it) * 1974-06-13 1978-06-29
FR2275220A1 (fr) * 1974-06-21 1976-01-16 Merieux Inst Procede d'obtention de sels organiques de la s.adenosyl-l-methionine. nouveaux sels organiques obtenus des medicaments comprenant un ou plusieurs nouveaux sels obtenus
JPS516989A (en) * 1974-07-05 1976-01-20 Yamasa Shoyu Kk Ss adenoshiru ll echioninno seiseiho
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
GB2001976B (en) * 1977-08-03 1982-03-10 Yamasa Shoyu Kk S-adenosyl-l-methionine compositions and production thereof
JPS5619879A (en) * 1979-07-25 1981-02-24 Showa Electric Wire & Cable Co Method of molding cable connector
GB2064523B (en) * 1979-12-04 1983-06-29 Kanegafuchi Chemical Ind Stable composition of s-adenosyl-l-methionine
JPS57192399A (en) * 1981-05-18 1982-11-26 Kanegafuchi Chem Ind Co Ltd Composition containing s-adenosyl-l-methionine and its preparation

Also Published As

Publication number Publication date
FI822944L (fi) 1983-02-25
PL238024A1 (en) 1983-05-09
HU186108B (en) 1985-06-28
NO153370C (no) 1986-03-05
IT8123603A0 (it) 1981-08-24
ATE16394T1 (de) 1985-11-15
FI72525C (fi) 1987-06-08
PT75454A (en) 1982-09-01
CA1201434A (en) 1986-03-04
NO153370B (no) 1985-11-25
PL137816B1 (en) 1986-07-31
AU552466B2 (en) 1986-06-05
DK377282A (da) 1983-02-25
AU8740582A (en) 1983-03-03
CZ614282A3 (en) 1995-04-12
JPH0149274B2 (it) 1989-10-24
DD210455A1 (de) 1984-06-13
DK149861C (da) 1987-03-02
JPS5843995A (ja) 1983-03-14
FI72525B (fi) 1987-02-27
NO822863L (no) 1983-02-25
ES515191A0 (es) 1983-06-01
ES8306371A1 (es) 1983-06-01
DE3267295D1 (en) 1985-12-12
YU42793B (en) 1988-12-31
IL66584A0 (en) 1982-12-31
ZA825971B (en) 1983-06-29
US4543408A (en) 1985-09-24
EP0073376B1 (en) 1985-11-06
GR76862B (it) 1984-09-04
DK149861B (da) 1986-10-13
CZ279834B6 (cs) 1995-07-12
PT75454B (en) 1984-11-19
EP0073376A1 (en) 1983-03-09
AR231453A1 (es) 1984-11-30
FI822944A0 (fi) 1982-08-24
NZ201679A (en) 1986-04-11
YU190882A (en) 1985-04-30
EP0073376B2 (en) 1989-07-26

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