CN101389641B - 来自菌株产加尔巴丁游动放线菌和利古里亚游动放线菌中的羊毛硫细菌素的生物合成成簇基因 - Google Patents

来自菌株产加尔巴丁游动放线菌和利古里亚游动放线菌中的羊毛硫细菌素的生物合成成簇基因 Download PDF

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CN101389641B
CN101389641B CN2007800067480A CN200780006748A CN101389641B CN 101389641 B CN101389641 B CN 101389641B CN 2007800067480 A CN2007800067480 A CN 2007800067480A CN 200780006748 A CN200780006748 A CN 200780006748A CN 101389641 B CN101389641 B CN 101389641B
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actagardin
seq
sequence
polypeptide
gene
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CN101389641A (zh
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史蒂文·博克斯
赫苏斯·科尔特斯巴尔加略
迈克尔·约翰·道森
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Novacta Biosystems Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes

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  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN2007800067480A 2006-01-17 2007-01-17 来自菌株产加尔巴丁游动放线菌和利古里亚游动放线菌中的羊毛硫细菌素的生物合成成簇基因 Expired - Fee Related CN101389641B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0600928.6 2006-01-17
GBGB0600928.6A GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics
PCT/GB2007/000138 WO2007083112A2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae

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CN101389641A CN101389641A (zh) 2009-03-18
CN101389641B true CN101389641B (zh) 2013-06-05

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US (3) US7989416B2 (https=)
EP (2) EP1979375B9 (https=)
JP (1) JP5219837B2 (https=)
KR (1) KR101573536B1 (https=)
CN (1) CN101389641B (https=)
AT (1) ATE534659T1 (https=)
AU (1) AU2007206769B2 (https=)
BR (1) BRPI0706525A2 (https=)
CA (1) CA2637315A1 (https=)
CY (1) CY1112559T1 (https=)
DK (1) DK1979375T3 (https=)
ES (1) ES2378090T3 (https=)
GB (1) GB0600928D0 (https=)
IL (1) IL192446A0 (https=)
MX (1) MX2008009047A (https=)
NZ (1) NZ569486A (https=)
PL (1) PL1979375T3 (https=)
PT (1) PT1979375E (https=)
SI (1) SI1979375T1 (https=)
WO (1) WO2007083112A2 (https=)

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GB201013508D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
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EP2925342A4 (en) * 2012-11-30 2016-07-06 Naicons Srl NOVEL LANTIBIOTIC DERIVATIVES AND PREPARATION METHOD THEREOF
CN103483433B (zh) * 2013-09-10 2015-05-27 中国科学院微生物研究所 一种新型高效的羊毛硫细菌素cerecidin及其应用
CN106188253B (zh) * 2016-08-26 2020-08-18 上海交通大学 抗菌肽Lexapeptide及其制备方法和用途
CN113777306A (zh) * 2020-06-09 2021-12-10 首都医科大学附属北京世纪坛医院 尿液果糖二磷酸醛缩酶b及其多肽片段在烧伤中的应用
CN115637247B (zh) * 2021-07-20 2026-02-24 中国科学院微生物研究所 生物氧化脱硫的盐单胞菌工程菌株及其全细胞催化脱硫方法

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GB0600928D0 (en) 2006-02-22
CA2637315A1 (en) 2007-07-26
KR101573536B1 (ko) 2015-12-11
DK1979375T3 (da) 2012-03-19
SI1979375T1 (sl) 2012-03-30
PT1979375E (pt) 2012-03-06
US8465947B2 (en) 2013-06-18
US20110306091A1 (en) 2011-12-15
EP1979375B9 (en) 2012-05-09
US7989416B2 (en) 2011-08-02
JP2009523777A (ja) 2009-06-25
BRPI0706525A2 (pt) 2011-03-29
EP1979375A2 (en) 2008-10-15
US20100048459A1 (en) 2010-02-25
NZ569486A (en) 2011-07-29
IL192446A0 (en) 2008-12-29
ES2378090T3 (es) 2012-04-04
AU2007206769B2 (en) 2013-06-20
ATE534659T1 (de) 2011-12-15
MX2008009047A (es) 2008-12-18
CN101389641A (zh) 2009-03-18
EP1979375B1 (en) 2011-11-23
JP5219837B2 (ja) 2013-06-26
USRE45003E1 (en) 2014-07-08
WO2007083112A2 (en) 2007-07-26
AU2007206769A1 (en) 2007-07-26
EP2189472A1 (en) 2010-05-26
WO2007083112A3 (en) 2008-05-08
PL1979375T3 (pl) 2012-04-30
CY1112559T1 (el) 2016-02-10
KR20080086517A (ko) 2008-09-25

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