GB0600928D0 - Improvements relating to lantibiotics - Google Patents

Improvements relating to lantibiotics

Info

Publication number
GB0600928D0
GB0600928D0 GBGB0600928.6A GB0600928A GB0600928D0 GB 0600928 D0 GB0600928 D0 GB 0600928D0 GB 0600928 A GB0600928 A GB 0600928A GB 0600928 D0 GB0600928 D0 GB 0600928D0
Authority
GB
United Kingdom
Prior art keywords
actagardine
lantibiotics
improvements relating
variant
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0600928.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novacta Biosystems Ltd
Original Assignee
Novacta Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novacta Biosystems Ltd filed Critical Novacta Biosystems Ltd
Priority to GBGB0600928.6A priority Critical patent/GB0600928D0/en
Publication of GB0600928D0 publication Critical patent/GB0600928D0/en
Priority to NZ569486A priority patent/NZ569486A/en
Priority to EP07704921A priority patent/EP1979375B9/en
Priority to BRPI0706525-6A priority patent/BRPI0706525A2/pt
Priority to CN2007800067480A priority patent/CN101389641B/zh
Priority to AT07704921T priority patent/ATE534659T1/de
Priority to PL07704921T priority patent/PL1979375T3/pl
Priority to JP2008550839A priority patent/JP5219837B2/ja
Priority to PT07704921T priority patent/PT1979375E/pt
Priority to ES07704921T priority patent/ES2378090T3/es
Priority to DK07704921.1T priority patent/DK1979375T3/da
Priority to KR1020087018136A priority patent/KR101573536B1/ko
Priority to EP20100000424 priority patent/EP2189472A1/en
Priority to US13/705,010 priority patent/USRE45003E1/en
Priority to MX2008009047A priority patent/MX2008009047A/es
Priority to CA002637315A priority patent/CA2637315A1/en
Priority to US12/161,221 priority patent/US7989416B2/en
Priority to AU2007206769A priority patent/AU2007206769B2/en
Priority to PCT/GB2007/000138 priority patent/WO2007083112A2/en
Priority to SI200730846T priority patent/SI1979375T1/sl
Priority to IL192446A priority patent/IL192446A0/en
Priority to US13/157,454 priority patent/US8465947B2/en
Priority to CY20121100166T priority patent/CY1112559T1/el
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/365Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinoplanes (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GBGB0600928.6A 2006-01-17 2006-01-17 Improvements relating to lantibiotics Ceased GB0600928D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GBGB0600928.6A GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics
SI200730846T SI1979375T1 (sl) 2006-01-17 2007-01-17 Lantibiotični biosintetični skupki genov iz A garbadinensis in A liguriae
DK07704921.1T DK1979375T3 (da) 2006-01-17 2007-01-17 Lantibiotiske, biosyntetiske genklynger fra A. garbadinensis og A. liguriae
EP20100000424 EP2189472A1 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae
BRPI0706525-6A BRPI0706525A2 (pt) 2006-01-17 2007-01-17 grupamentos genéticos biossintéticos de lantiobióticos de a. garbadinensis e a. liguriae
CN2007800067480A CN101389641B (zh) 2006-01-17 2007-01-17 来自菌株产加尔巴丁游动放线菌和利古里亚游动放线菌中的羊毛硫细菌素的生物合成成簇基因
AT07704921T ATE534659T1 (de) 2006-01-17 2007-01-17 Biosynthetische gencluster für lantibiotikum aus a. garbadinensis und a. liguriae
PL07704921T PL1979375T3 (pl) 2006-01-17 2007-01-17 Klastry biosyntetycznych genów kodujących lantybiotyki pochodzące od a. garbadinensis oraz a. liguriae
JP2008550839A JP5219837B2 (ja) 2006-01-17 2007-01-17 A.ガルバジネンシスおよびa.リグリエに由来するランチビオティック生合成遺伝子クラスター
PT07704921T PT1979375E (pt) 2006-01-17 2007-01-17 Aglomerados de genes biossintéticos lantibióticos de a. garbadinensis e a. liguriae
ES07704921T ES2378090T3 (es) 2006-01-17 2007-01-17 Clústeres de genes biosintéticos lantibióticos a partir de A. garbadinensis y A. liguriae
NZ569486A NZ569486A (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A.garbadinensis and A.liguriae
KR1020087018136A KR101573536B1 (ko) 2006-01-17 2007-01-17 악티노플레인스 가르바디넨시스 및 악티노플레인스리구리애로부터의 란티바이오틱 생합성 유전자 클러스터
EP07704921A EP1979375B9 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae
US13/705,010 USRE45003E1 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae
MX2008009047A MX2008009047A (es) 2006-01-17 2007-01-17 Grupos de genes biosinteticos lantibioticos de a. garbadinesis y a. liguriae.
CA002637315A CA2637315A1 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae
US12/161,221 US7989416B2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. Liguriae
AU2007206769A AU2007206769B2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae
PCT/GB2007/000138 WO2007083112A2 (en) 2006-01-17 2007-01-17 Lantibiotic biosynthetic gene clusters from a. garbadinensis and a. liguriae
IL192446A IL192446A0 (en) 2006-01-17 2008-06-25 Lantibiotic biosynthetic gene clusters form a. garbadinensis and a. liguriae
US13/157,454 US8465947B2 (en) 2006-01-17 2011-06-10 Lantibiotic biosynthetic gene clusters from A. garbadinensis and A. liguriae
CY20121100166T CY1112559T1 (el) 2006-01-17 2012-02-17 Βιοσυνθετικα συναθροισματα γονιδιων λαντιβιοτικων απο α. garbadinensis και α. liguriae

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0600928.6A GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics

Publications (1)

Publication Number Publication Date
GB0600928D0 true GB0600928D0 (en) 2006-02-22

Family

ID=35998187

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0600928.6A Ceased GB0600928D0 (en) 2006-01-17 2006-01-17 Improvements relating to lantibiotics

Country Status (20)

Country Link
US (3) US7989416B2 (https=)
EP (2) EP1979375B9 (https=)
JP (1) JP5219837B2 (https=)
KR (1) KR101573536B1 (https=)
CN (1) CN101389641B (https=)
AT (1) ATE534659T1 (https=)
AU (1) AU2007206769B2 (https=)
BR (1) BRPI0706525A2 (https=)
CA (1) CA2637315A1 (https=)
CY (1) CY1112559T1 (https=)
DK (1) DK1979375T3 (https=)
ES (1) ES2378090T3 (https=)
GB (1) GB0600928D0 (https=)
IL (1) IL192446A0 (https=)
MX (1) MX2008009047A (https=)
NZ (1) NZ569486A (https=)
PL (1) PL1979375T3 (https=)
PT (1) PT1979375E (https=)
SI (1) SI1979375T1 (https=)
WO (1) WO2007083112A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714030D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) * 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
CA2749278A1 (en) * 2009-01-14 2010-07-22 Novacta Biosystems Limited Deoxyactagardine derivatives
GB0900599D0 (en) 2009-01-14 2009-02-18 Novacta Biosystems Ltd Treatment
CN102388060B (zh) * 2009-02-04 2014-09-10 诺瓦克塔生物系统有限公司 阿肽加定衍生物
CA2789164A1 (en) 2010-02-02 2011-08-11 Novacta Biosystems Limited Lantibiotic salts
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
EA201291461A1 (ru) 2010-07-14 2013-08-30 Новакта Биосистемс Лимитед Состав, содержащий лантибиотик типа b
GB201013508D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013507D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) * 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
GB201013509D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Compounds
EP2925342A4 (en) * 2012-11-30 2016-07-06 Naicons Srl NOVEL LANTIBIOTIC DERIVATIVES AND PREPARATION METHOD THEREOF
CN103483433B (zh) * 2013-09-10 2015-05-27 中国科学院微生物研究所 一种新型高效的羊毛硫细菌素cerecidin及其应用
CN106188253B (zh) * 2016-08-26 2020-08-18 上海交通大学 抗菌肽Lexapeptide及其制备方法和用途
CN113777306A (zh) * 2020-06-09 2021-12-10 首都医科大学附属北京世纪坛医院 尿液果糖二磷酸醛缩酶b及其多肽片段在烧伤中的应用
CN115637247B (zh) * 2021-07-20 2026-02-24 中国科学院微生物研究所 生物氧化脱硫的盐单胞菌工程菌株及其全细胞催化脱硫方法

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
GB8507528D0 (en) 1985-03-22 1985-05-01 Lepetit Spa Basis monocarboxyamide derivatives
US5304540A (en) 1988-06-22 1994-04-19 Applied Microbiology, Inc. Pharmaceutical bacteriocin compositions and methods for using the same
IN167138B (https=) 1988-08-17 1990-09-01 Hoechst India
GB8926639D0 (en) 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations
KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
IT1260505B (it) 1992-06-01 1996-04-09 Poli Ind Chimica Spa Sistemi farmaceutici orali a cessione ritardata per il rilascio specifico nel colon
IL107887A (en) 1992-12-08 2003-07-06 Ambi Inc Stabilized lanthionine containing bacteriocin compositions
US5512269A (en) 1993-06-09 1996-04-30 Burroughs Wellcome, Co. Method of treating retained pulmonary secretions
EP0700998B1 (en) 1994-09-12 2003-11-26 Aventis Pharma Deutschland GmbH Recombinant mersacidin and a method for production
NZ311535A (en) 1995-06-23 2001-05-25 Ambi Inc A method for the control of antibiotic-resistant gram positive bacteria and treatment of infection
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
US5958873A (en) 1997-06-09 1999-09-28 University Of Cincinnati Oral formulation for treatment of bacteria-induced diseases of the colon
US5985823A (en) 1997-06-09 1999-11-16 Ambi Inc. Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon
DE19745583A1 (de) * 1997-10-15 1999-04-22 Hoechst Marion Roussel De Gmbh Neues Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung derselben
US6569830B1 (en) 1999-03-05 2003-05-27 Ambi, Inc. Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains
KR100786927B1 (ko) 2000-06-28 2007-12-17 스미스클라인비이참피이엘시이 습식 분쇄방법
GB0110432D0 (en) * 2001-04-27 2001-06-20 Plant Bioscience Ltd Lantibiotic production
WO2002103010A1 (en) 2001-06-14 2002-12-27 Plant Bioscience Limited Methods and materials for targeted gene disruption in actinomycete bacteria
US6861236B2 (en) 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way
AU2003275129A1 (en) 2002-10-10 2004-05-04 Molichem Medicines, Inc. Nucleic acids encoding duramycin
US7351687B2 (en) 2003-07-18 2008-04-01 Vicuron Pharmaceuticals, Inc. Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof
ES2281808T3 (es) 2003-07-18 2007-10-01 Vicuron Pharmaceuticals, Inc. Antibiotico 107891, sus factores a1 y a2, composiciones y sales farmaceuticamente aceptables y uso del mismo.
WO2005079508A2 (en) * 2004-02-17 2005-09-01 Cancervax Corporation Method and composition for angiogenesis inhibition
GB0406870D0 (en) 2004-03-26 2004-04-28 Novacta Biosystems Ltd Improvements relating to the production of lantibiotics
WO2007036706A1 (en) 2005-09-27 2007-04-05 Novacta Biosystems Limited Variants of the lantibiotic mersacidin and their use
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
CN101595133B (zh) 2006-10-27 2012-11-14 比利时胶囊公司 羟丙基甲基纤维素硬胶囊及制备方法
CA2690267A1 (en) 2007-06-12 2008-12-18 The University Of British Columbia Small cationic antimicrobial peptides
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
GB0714030D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
KR20110086582A (ko) 2008-11-24 2011-07-28 센티넬라 파마세티컬즈, 인크. 항균활성이 강화된 란티바이오틱 카르복시아미드 유도체
CA2749278A1 (en) 2009-01-14 2010-07-22 Novacta Biosystems Limited Deoxyactagardine derivatives
GB0900599D0 (en) 2009-01-14 2009-02-18 Novacta Biosystems Ltd Treatment
CN102388060B (zh) 2009-02-04 2014-09-10 诺瓦克塔生物系统有限公司 阿肽加定衍生物
EP2216937A1 (en) 2009-02-10 2010-08-11 Alcatel Lucent Alarm notification between customer premises equipment and a remote management server

Also Published As

Publication number Publication date
CA2637315A1 (en) 2007-07-26
KR101573536B1 (ko) 2015-12-11
DK1979375T3 (da) 2012-03-19
SI1979375T1 (sl) 2012-03-30
PT1979375E (pt) 2012-03-06
US8465947B2 (en) 2013-06-18
US20110306091A1 (en) 2011-12-15
EP1979375B9 (en) 2012-05-09
US7989416B2 (en) 2011-08-02
JP2009523777A (ja) 2009-06-25
BRPI0706525A2 (pt) 2011-03-29
EP1979375A2 (en) 2008-10-15
US20100048459A1 (en) 2010-02-25
NZ569486A (en) 2011-07-29
IL192446A0 (en) 2008-12-29
ES2378090T3 (es) 2012-04-04
AU2007206769B2 (en) 2013-06-20
ATE534659T1 (de) 2011-12-15
MX2008009047A (es) 2008-12-18
CN101389641A (zh) 2009-03-18
EP1979375B1 (en) 2011-11-23
JP5219837B2 (ja) 2013-06-26
USRE45003E1 (en) 2014-07-08
WO2007083112A2 (en) 2007-07-26
AU2007206769A1 (en) 2007-07-26
EP2189472A1 (en) 2010-05-26
WO2007083112A3 (en) 2008-05-08
PL1979375T3 (pl) 2012-04-30
CY1112559T1 (el) 2016-02-10
CN101389641B (zh) 2013-06-05
KR20080086517A (ko) 2008-09-25

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Legal Events

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AT Applications terminated before publication under section 16(1)