ES2343767T3 - Composiciones anestesicas liposomicas de liberacion sostenida. - Google Patents
Composiciones anestesicas liposomicas de liberacion sostenida. Download PDFInfo
- Publication number
- ES2343767T3 ES2343767T3 ES98948352T ES98948352T ES2343767T3 ES 2343767 T3 ES2343767 T3 ES 2343767T3 ES 98948352 T ES98948352 T ES 98948352T ES 98948352 T ES98948352 T ES 98948352T ES 2343767 T3 ES2343767 T3 ES 2343767T3
- Authority
- ES
- Spain
- Prior art keywords
- bupivacaine
- anesthetic
- composition
- acid
- lmv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5923397P | 1997-09-18 | 1997-09-18 | |
| US59233 | 1997-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2343767T3 true ES2343767T3 (es) | 2010-08-09 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
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| ES10003091T Expired - Lifetime ES2373861T3 (es) | 1997-09-18 | 1998-09-18 | Composiciones anestésicas liposomiales de liberación sostenida. |
| ES98948352T Expired - Lifetime ES2343767T3 (es) | 1997-09-18 | 1998-09-18 | Composiciones anestesicas liposomicas de liberacion sostenida. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10003091T Expired - Lifetime ES2373861T3 (es) | 1997-09-18 | 1998-09-18 | Composiciones anestésicas liposomiales de liberación sostenida. |
Country Status (15)
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| US (5) | US6045824A (enExample) |
| EP (3) | EP2198854B1 (enExample) |
| JP (1) | JP4467789B2 (enExample) |
| AT (2) | ATE535232T1 (enExample) |
| AU (1) | AU735588B2 (enExample) |
| CA (1) | CA2304096C (enExample) |
| CY (1) | CY1110135T1 (enExample) |
| DE (1) | DE69841598D1 (enExample) |
| DK (1) | DK1014946T3 (enExample) |
| ES (2) | ES2373861T3 (enExample) |
| IL (1) | IL135060A (enExample) |
| NO (1) | NO329727B1 (enExample) |
| NZ (1) | NZ503513A (enExample) |
| PT (1) | PT1014946E (enExample) |
| WO (1) | WO1999013865A1 (enExample) |
Families Citing this family (88)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2198854B1 (en) * | 1997-09-18 | 2011-11-30 | Pacira Pharmaceuticals, Inc. | Sustained-release liposomal anesthetic compositions |
| ES2384094T3 (es) * | 1997-11-14 | 2012-06-29 | Pacira Pharmaceuticals, Inc. | Producción de liposomas multivesiculares |
| IL146567A0 (en) * | 1999-06-04 | 2002-07-25 | Skyepharma Inc | Oil-core particles containing a hydrophobic core material and hydrophobic drug and method for the preparation thereof |
| US6566575B1 (en) | 2000-02-15 | 2003-05-20 | 3M Innovative Properties Company | Patterned absorbent article for wound dressing |
| US6977323B1 (en) | 2000-02-17 | 2005-12-20 | 3M Innovative Properties Company | Foam-on-film medical articles |
| US6716186B1 (en) | 2000-08-16 | 2004-04-06 | 3M Innovative Properties Company | Curable adhesive splints and methods |
| US6903243B1 (en) | 2000-09-08 | 2005-06-07 | 3M Innovative Properties Company | Multi-layer absorbent wound dressing |
| NZ529544A (en) * | 2001-05-31 | 2006-11-30 | Skyepharma Inc | Encapsulation of nanosuspensions in liposomes and microspheres |
| US7476400B2 (en) * | 2001-11-13 | 2009-01-13 | Ferndale Ip, Inc. | High-concentration lidocaine compositions and methods for their preparation |
| US7005143B2 (en) | 2002-04-12 | 2006-02-28 | 3M Innovative Properties Company | Gel materials, medical articles, and methods |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| US7612248B2 (en) | 2002-12-19 | 2009-11-03 | 3M Innovative Properties Company | Absorbent medical articles |
| US20050070688A1 (en) | 2003-09-26 | 2005-03-31 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7384984B2 (en) | 2003-12-10 | 2008-06-10 | 3M Innovative Properties Company | Reactive hydrophilic oligomers |
| US7074839B2 (en) | 2004-03-01 | 2006-07-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent photoinitiator groups |
| US7342047B2 (en) | 2004-03-02 | 2008-03-11 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups |
| US20060029657A1 (en) * | 2004-03-26 | 2006-02-09 | Stiefel Laboratories, Inc. | Topical skin protectant compositions |
| US7335690B2 (en) | 2005-01-25 | 2008-02-26 | 3M Innovative Properties Company | Crosslinkable hydrophilic materials from polymers having pendent Michael donor groups |
| US8609131B2 (en) | 2005-01-25 | 2013-12-17 | 3M Innovative Properties Company | Absorbent dressing comprising hydrophilic polymer prepared via Michael reaction |
| EA200802166A1 (ru) | 2006-04-20 | 2009-06-30 | Эмджен Инк. | Стабильная фармацевтическая композиция с защитным действием от раздражения (варианты), способ ее получения и способ лечения кальций-миметиком с ее помощью |
| US7981949B2 (en) | 2006-05-23 | 2011-07-19 | 3M Innovative Properties Company | Curable hydrophilic compositions |
| KR101470045B1 (ko) * | 2007-05-29 | 2014-12-05 | 포라 가세이 고교 가부시키가이샤 | 피부 외용제에 유용한 베시클 및 상기 베시클을 함유하는 피부 외용제 |
| CN102223878A (zh) | 2008-10-07 | 2011-10-19 | 耶路撒冷希伯来大学伊森姆研究发展公司 | 包含鞘磷脂的脂质体系统 |
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| US5865184A (en) | 1997-01-13 | 1999-02-02 | Takiguchi; Tetsuo | Combined spinal and epidural anesthesia |
| US5891467A (en) | 1997-01-31 | 1999-04-06 | Depotech Corporation | Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes |
| US5827533A (en) * | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
| US5864184A (en) * | 1997-03-05 | 1999-01-26 | Brian Page Platner | Interface circuitry for facilitating installation of a control device |
| DE69806246T3 (de) | 1997-03-13 | 2006-05-18 | Campbell, James N. | Zusammensetzung enthaltend capsaicin oder seine analogen und lokalanästhetika |
| US6106858A (en) * | 1997-09-08 | 2000-08-22 | Skyepharma, Inc. | Modulation of drug loading in multivescular liposomes |
| US6306432B1 (en) | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
| EP2198854B1 (en) * | 1997-09-18 | 2011-11-30 | Pacira Pharmaceuticals, Inc. | Sustained-release liposomal anesthetic compositions |
| US5955476A (en) * | 1997-11-18 | 1999-09-21 | Celgene Corporation | Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels |
-
1998
- 1998-09-18 EP EP10003091A patent/EP2198854B1/en not_active Expired - Lifetime
- 1998-09-18 JP JP2000511489A patent/JP4467789B2/ja not_active Expired - Lifetime
- 1998-09-18 US US09/156,214 patent/US6045824A/en not_active Expired - Lifetime
- 1998-09-18 ES ES10003091T patent/ES2373861T3/es not_active Expired - Lifetime
- 1998-09-18 EP EP98948352A patent/EP1014946B1/en not_active Expired - Lifetime
- 1998-09-18 WO PCT/US1998/019583 patent/WO1999013865A1/en not_active Ceased
- 1998-09-18 IL IL13506098A patent/IL135060A/xx not_active IP Right Cessation
- 1998-09-18 NZ NZ503513A patent/NZ503513A/xx not_active IP Right Cessation
- 1998-09-18 AT AT10003091T patent/ATE535232T1/de active
- 1998-09-18 ES ES98948352T patent/ES2343767T3/es not_active Expired - Lifetime
- 1998-09-18 CA CA002304096A patent/CA2304096C/en not_active Expired - Lifetime
- 1998-09-18 EP EP10183360A patent/EP2308470A1/en not_active Withdrawn
- 1998-09-18 PT PT98948352T patent/PT1014946E/pt unknown
- 1998-09-18 DE DE69841598T patent/DE69841598D1/de not_active Expired - Lifetime
- 1998-09-18 AT AT98948352T patent/ATE463238T1/de active
- 1998-09-18 AU AU94942/98A patent/AU735588B2/en not_active Expired
- 1998-09-18 DK DK98948352.4T patent/DK1014946T3/da active
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2000
- 2000-03-17 NO NO20001410A patent/NO329727B1/no not_active IP Right Cessation
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2005
- 2005-04-01 US US11/097,756 patent/US8182835B2/en not_active Expired - Fee Related
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2010
- 2010-06-22 CY CY20101100573T patent/CY1110135T1/el unknown
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2012
- 2012-05-21 US US13/476,823 patent/US8834921B2/en not_active Expired - Fee Related
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2013
- 2013-03-06 US US13/787,690 patent/US9192575B2/en not_active Expired - Fee Related
- 2013-03-15 US US13/842,198 patent/US9205052B2/en not_active Expired - Fee Related
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