ES2286429T3 - Procedimiento de preparacion de modafinilo. - Google Patents

Procedimiento de preparacion de modafinilo. Download PDF

Info

Publication number
ES2286429T3
ES2286429T3 ES03725083T ES03725083T ES2286429T3 ES 2286429 T3 ES2286429 T3 ES 2286429T3 ES 03725083 T ES03725083 T ES 03725083T ES 03725083 T ES03725083 T ES 03725083T ES 2286429 T3 ES2286429 T3 ES 2286429T3
Authority
ES
Spain
Prior art keywords
diphenylmethyl
sulfinyl
procedure
acid
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03725083T
Other languages
English (en)
Spanish (es)
Inventor
Graziano Castaldi
Vittorio Lucchini
Antonio Tarquini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dipharma Francis SRL
Original Assignee
Dipharma Francis SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Francis SRL filed Critical Dipharma Francis SRL
Application granted granted Critical
Publication of ES2286429T3 publication Critical patent/ES2286429T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
ES03725083T 2002-05-10 2003-04-23 Procedimiento de preparacion de modafinilo. Expired - Lifetime ES2286429T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002MI000991A ITMI20020991A1 (it) 2002-05-10 2002-05-10 Procedimento per la sintesi del modafinil
ITMI02A0991 2002-05-10

Publications (1)

Publication Number Publication Date
ES2286429T3 true ES2286429T3 (es) 2007-12-01

Family

ID=11449867

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03725083T Expired - Lifetime ES2286429T3 (es) 2002-05-10 2003-04-23 Procedimiento de preparacion de modafinilo.

Country Status (17)

Country Link
US (1) US7057068B2 (enExample)
EP (1) EP1503983B1 (enExample)
JP (1) JP4351626B2 (enExample)
KR (1) KR20040108789A (enExample)
AT (1) ATE364593T1 (enExample)
AU (1) AU2003227668A1 (enExample)
CA (1) CA2485428A1 (enExample)
DE (1) DE60314410T2 (enExample)
DK (1) DK1503983T3 (enExample)
EA (1) EA007327B1 (enExample)
ES (1) ES2286429T3 (enExample)
IL (1) IL165121A0 (enExample)
IT (1) ITMI20020991A1 (enExample)
MX (1) MXPA04011141A (enExample)
PL (1) PL371679A1 (enExample)
PT (1) PT1503983E (enExample)
WO (1) WO2003095423A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101098749B1 (ko) 2000-07-27 2011-12-23 테바 파마슈티컬 인더스트리즈 리미티드 결정질의 순수한 모다피닐 및 이의 제조 방법
ITMI20051971A1 (it) * 2005-10-18 2007-04-19 Dipharma Spa Procedimento per la preparazione di - modafinil
US20070293702A1 (en) * 2006-02-21 2007-12-20 Viviana Braude Novel crystalline forms of armodafinil and preparation thereof
CA2634133A1 (en) * 2006-03-01 2007-09-13 Teva Pharmaceutical Industries Ltd. An improved process for the preparation of armodafinil
BRPI0714173A2 (pt) * 2006-07-12 2012-12-25 Elan Pharma Int Ltd composiÇço nanoparticulada estÁvel,mÉtodos para preparar a composiÇço, para prevenir e/ou tratar estados de doenÇas, sintomas, sÍndromes e condiÇÕes do sistema nervoso central, para melhorar ou manter a biodisponibilidade de modafinil, e para tratar distérbio com base neurolàgica, composiÇço farmacÊutica, e forma de dosagem
US7960586B2 (en) * 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
EP1911739A3 (en) 2007-11-05 2008-09-17 Dipharma Francis S.r.l. Crystalline form of (S)-2-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement
CN114044730B (zh) * 2021-11-26 2024-04-23 台州学院 一种亚砜类化合物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE221261C (enExample) *
DE2546319C2 (de) * 1975-10-16 1986-02-27 Dr. Karl Thomae Gmbh, 7950 Biberach Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
US4964893A (en) * 1986-04-17 1990-10-23 Monsanto Company Benzhydryl compounds as herbicide antidotes
KR101098749B1 (ko) 2000-07-27 2011-12-23 테바 파마슈티컬 인더스트리즈 리미티드 결정질의 순수한 모다피닐 및 이의 제조 방법

Also Published As

Publication number Publication date
US20050154063A1 (en) 2005-07-14
PT1503983E (pt) 2007-07-31
ITMI20020991A0 (it) 2002-05-10
US7057068B2 (en) 2006-06-06
WO2003095423A1 (en) 2003-11-20
PL371679A1 (en) 2005-06-27
ITMI20020991A1 (it) 2003-11-10
DK1503983T3 (da) 2007-09-10
CA2485428A1 (en) 2003-11-20
AU2003227668A1 (en) 2003-11-11
EP1503983A1 (en) 2005-02-09
IL165121A0 (en) 2005-12-18
ATE364593T1 (de) 2007-07-15
MXPA04011141A (es) 2005-07-01
JP2005525420A (ja) 2005-08-25
EA007327B1 (ru) 2006-08-25
JP4351626B2 (ja) 2009-10-28
EA200401235A1 (ru) 2005-06-30
DE60314410T2 (de) 2008-02-14
KR20040108789A (ko) 2004-12-24
DE60314410D1 (de) 2007-07-26
EP1503983B1 (en) 2007-06-13

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