DE60314410D1 - Verfahren zur herstellung von modafinil - Google Patents

Verfahren zur herstellung von modafinil

Info

Publication number
DE60314410D1
DE60314410D1 DE60314410T DE60314410T DE60314410D1 DE 60314410 D1 DE60314410 D1 DE 60314410D1 DE 60314410 T DE60314410 T DE 60314410T DE 60314410 T DE60314410 T DE 60314410T DE 60314410 D1 DE60314410 D1 DE 60314410D1
Authority
DE
Germany
Prior art keywords
producing modafinil
modafinil
producing
diphenylmethyl
sulfenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60314410T
Other languages
English (en)
Other versions
DE60314410T2 (de
Inventor
Graziano Castaldi
Vittorio Lucchini
Antonio Tarquini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dipharma Francis SRL
Original Assignee
Dipharma Francis SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Francis SRL filed Critical Dipharma Francis SRL
Application granted granted Critical
Publication of DE60314410D1 publication Critical patent/DE60314410D1/de
Publication of DE60314410T2 publication Critical patent/DE60314410T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Liquid Crystal (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
DE60314410T 2002-05-10 2003-04-23 Verfahren zur herstellung von modafinil Expired - Lifetime DE60314410T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI20020991 2002-05-10
IT2002MI000991A ITMI20020991A1 (it) 2002-05-10 2002-05-10 Procedimento per la sintesi del modafinil
PCT/EP2003/004229 WO2003095423A1 (en) 2002-05-10 2003-04-23 A process for the preparation of modafinil

Publications (2)

Publication Number Publication Date
DE60314410D1 true DE60314410D1 (de) 2007-07-26
DE60314410T2 DE60314410T2 (de) 2008-02-14

Family

ID=11449867

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60314410T Expired - Lifetime DE60314410T2 (de) 2002-05-10 2003-04-23 Verfahren zur herstellung von modafinil

Country Status (17)

Country Link
US (1) US7057068B2 (de)
EP (1) EP1503983B1 (de)
JP (1) JP4351626B2 (de)
KR (1) KR20040108789A (de)
AT (1) ATE364593T1 (de)
AU (1) AU2003227668A1 (de)
CA (1) CA2485428A1 (de)
DE (1) DE60314410T2 (de)
DK (1) DK1503983T3 (de)
EA (1) EA007327B1 (de)
ES (1) ES2286429T3 (de)
IL (1) IL165121A0 (de)
IT (1) ITMI20020991A1 (de)
MX (1) MXPA04011141A (de)
PL (1) PL371679A1 (de)
PT (1) PT1503983E (de)
WO (1) WO2003095423A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2168946A1 (de) 2000-07-27 2010-03-31 Teva Pharmaceutical Industries Ltd Kirstalline Form von Modafinil und Verfahren zu deren Herstellung
ITMI20051971A1 (it) * 2005-10-18 2007-04-19 Dipharma Spa Procedimento per la preparazione di - modafinil
MX2007012605A (es) * 2006-02-21 2008-01-11 Teva Pharma Formas cristalinas novedosas de armodafinil y preparacion de ellas.
EP2159219A3 (de) * 2006-03-01 2010-12-15 Teva Pharmaceutical Industries Ltd. Verbessertes Verfahren zur Zubereitung von Armodafinil
JP2009543803A (ja) * 2006-07-12 2009-12-10 エラン・ファルマ・インターナショナル・リミテッド モダフィニルのナノ粒子製剤
US7960586B2 (en) * 2007-08-16 2011-06-14 Teva Pharmaceutical Industries Ltd. Purification of armodafinil
EP1911739A3 (de) 2007-11-05 2008-09-17 Dipharma Francis S.r.l. Kristallform von (S)-2-Phenylethylammonium-(R)-diphenylmethanesulfinylacetat
US9616068B2 (en) 2014-10-27 2017-04-11 Pohela LLC Animal training using cognitive enhancement
CN114044730B (zh) * 2021-11-26 2024-04-23 台州学院 一种亚砜类化合物的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE221261C (de) *
DE2546319C2 (de) * 1975-10-16 1986-02-27 Dr. Karl Thomae Gmbh, 7950 Biberach Cyclohexylphenyl-Derivate, Verfahren zu deren Herstellung und diese enthaltende Mittel
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
US4964893A (en) * 1986-04-17 1990-10-23 Monsanto Company Benzhydryl compounds as herbicide antidotes
EP2168946A1 (de) * 2000-07-27 2010-03-31 Teva Pharmaceutical Industries Ltd Kirstalline Form von Modafinil und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
DE60314410T2 (de) 2008-02-14
KR20040108789A (ko) 2004-12-24
JP4351626B2 (ja) 2009-10-28
WO2003095423A1 (en) 2003-11-20
DK1503983T3 (da) 2007-09-10
ATE364593T1 (de) 2007-07-15
ES2286429T3 (es) 2007-12-01
EP1503983B1 (de) 2007-06-13
US20050154063A1 (en) 2005-07-14
US7057068B2 (en) 2006-06-06
IL165121A0 (en) 2005-12-18
EA007327B1 (ru) 2006-08-25
MXPA04011141A (es) 2005-07-01
EP1503983A1 (de) 2005-02-09
EA200401235A1 (ru) 2005-06-30
PT1503983E (pt) 2007-07-31
PL371679A1 (en) 2005-06-27
CA2485428A1 (en) 2003-11-20
JP2005525420A (ja) 2005-08-25
AU2003227668A1 (en) 2003-11-11
ITMI20020991A1 (it) 2003-11-10
ITMI20020991A0 (it) 2002-05-10

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Legal Events

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