DE60219800D1 - Verfahren zur herstellung von cilastatin - Google Patents

Verfahren zur herstellung von cilastatin

Info

Publication number
DE60219800D1
DE60219800D1 DE60219800T DE60219800T DE60219800D1 DE 60219800 D1 DE60219800 D1 DE 60219800D1 DE 60219800 T DE60219800 T DE 60219800T DE 60219800 T DE60219800 T DE 60219800T DE 60219800 D1 DE60219800 D1 DE 60219800D1
Authority
DE
Germany
Prior art keywords
cilastatin
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60219800T
Other languages
English (en)
Other versions
DE60219800T2 (de
Inventor
Yatendra Kumar
Om Dutt Tyagi
Tushar Kumar Srivastava
Anand Pandey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Application granted granted Critical
Publication of DE60219800D1 publication Critical patent/DE60219800D1/de
Publication of DE60219800T2 publication Critical patent/DE60219800T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60219800T 2001-08-24 2002-08-23 Verfahren zur herstellung von cilastatin Expired - Fee Related DE60219800T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN879DE2001 IN192179B (de) 2001-08-24 2001-08-24
INDE08792001 2001-08-24
PCT/IB2002/003399 WO2003018544A1 (en) 2001-08-24 2002-08-23 Process for the preparation of cilastatin

Publications (2)

Publication Number Publication Date
DE60219800D1 true DE60219800D1 (de) 2007-06-06
DE60219800T2 DE60219800T2 (de) 2008-01-17

Family

ID=11097101

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60219800T Expired - Fee Related DE60219800T2 (de) 2001-08-24 2002-08-23 Verfahren zur herstellung von cilastatin

Country Status (15)

Country Link
US (1) US20050119346A1 (de)
EP (1) EP1423360B1 (de)
JP (1) JP2005525996A (de)
CN (1) CN1592737A (de)
AR (1) AR052751A1 (de)
AT (1) ATE360610T1 (de)
BR (1) BR0212390A (de)
CA (1) CA2458505A1 (de)
DE (1) DE60219800T2 (de)
ES (1) ES2282448T3 (de)
IN (1) IN192179B (de)
RU (1) RU2004108465A (de)
SI (1) SI1423360T1 (de)
WO (1) WO2003018544A1 (de)
ZA (1) ZA200402006B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100638471B1 (ko) * 2004-08-25 2006-10-25 동국제약 주식회사 실라스타틴 나트륨염의 신규한 제조 방법
ES2431275T3 (es) 2005-11-09 2013-11-25 Orchid Chemicals&Pharmaceuticals Limited Un procedimiento mejorado para la preparación de cilastatina ácida
KR100833202B1 (ko) * 2006-12-11 2008-05-28 (주)위즈켐 7-클로로-(2,2-디메틸시클로프로판카르복스아미도)-2-헵텐산 제조방법
CN101307015B (zh) * 2007-05-16 2012-06-13 深圳市海滨制药有限公司 一种制备西司他丁钠的方法
KR100913694B1 (ko) * 2008-07-09 2009-08-24 (주)하이텍팜 신규한 결정형 실라스타틴 암모늄염 및 그 제조방법
CN101851186B (zh) * 2010-05-31 2012-11-14 浙江师范大学 西司他丁钠的合成方法
CN102675175B (zh) * 2011-03-08 2014-02-19 深圳市海滨制药有限公司 一种西司他丁的分离纯化方法
CN102702051B (zh) * 2011-03-26 2016-04-13 山东新时代药业有限公司 一种西司他丁钠的制备方法
CN102875433A (zh) * 2012-10-29 2013-01-16 江西金顿香料有限公司 一种西司他丁酸的制备方法
CA2937311A1 (en) 2014-01-24 2015-07-30 Ea Pharma Co., Ltd. Megalin antagonist
CN104926701B (zh) * 2015-06-30 2017-05-03 西安蓝晓科技新材料股份有限公司 一种蛋氨酸纯化的工艺
CN107522642A (zh) * 2017-08-14 2017-12-29 新乡海滨药业有限公司 一种西司他丁的精制方法
CN115260067A (zh) * 2022-08-26 2022-11-01 同舟纵横（厦门）流体技术有限公司 一种西司他丁母液纯化的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147868A (en) * 1978-07-24 1992-09-15 Merck & Co., Inc. Thienamycin renal peptidase inhibitors

Also Published As

Publication number Publication date
DE60219800T2 (de) 2008-01-17
ZA200402006B (en) 2004-09-15
ATE360610T1 (de) 2007-05-15
ES2282448T3 (es) 2007-10-16
SI1423360T1 (sl) 2007-08-31
WO2003018544A1 (en) 2003-03-06
JP2005525996A (ja) 2005-09-02
RU2004108465A (ru) 2005-09-20
US20050119346A1 (en) 2005-06-02
BR0212390A (pt) 2004-07-27
EP1423360B1 (de) 2007-04-25
CN1592737A (zh) 2005-03-09
CA2458505A1 (en) 2003-03-06
IN192179B (de) 2004-03-06
AR052751A1 (es) 2007-04-04
EP1423360A1 (de) 2004-06-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee