ES2269093T3 - Metodo, sistema y cartucho para el procedimiento de una muestra de acido nucleico mediante la oscilacion del cartucho. - Google Patents

Metodo, sistema y cartucho para el procedimiento de una muestra de acido nucleico mediante la oscilacion del cartucho. Download PDF

Info

Publication number
ES2269093T3
ES2269093T3 ES00811253T ES00811253T ES2269093T3 ES 2269093 T3 ES2269093 T3 ES 2269093T3 ES 00811253 T ES00811253 T ES 00811253T ES 00811253 T ES00811253 T ES 00811253T ES 2269093 T3 ES2269093 T3 ES 2269093T3
Authority
ES
Spain
Prior art keywords
cartridge
chip
channel
active surface
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00811253T
Other languages
English (en)
Spanish (es)
Inventor
Peter Vischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2269093T3 publication Critical patent/ES2269093T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/10Mixers with shaking, oscillating, or vibrating mechanisms with a mixing receptacle rotating alternately in opposite directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20Mixing the contents of independent containers, e.g. test tubes
    • B01F31/201Holders therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/52Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/527Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0457Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00158Elements containing microarrays, i.e. "biochip"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00524Mixing by agitating sample carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/924Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Saccharide Compounds (AREA)
ES00811253T 2000-12-28 2000-12-28 Metodo, sistema y cartucho para el procedimiento de una muestra de acido nucleico mediante la oscilacion del cartucho. Expired - Lifetime ES2269093T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00811253A EP1224976B1 (en) 2000-12-28 2000-12-28 Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge

Publications (1)

Publication Number Publication Date
ES2269093T3 true ES2269093T3 (es) 2007-04-01

Family

ID=8175115

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00811253T Expired - Lifetime ES2269093T3 (es) 2000-12-28 2000-12-28 Metodo, sistema y cartucho para el procedimiento de una muestra de acido nucleico mediante la oscilacion del cartucho.

Country Status (7)

Country Link
US (2) US6921639B2 (enExample)
EP (2) EP1224976B1 (enExample)
JP (2) JP3970023B2 (enExample)
AT (1) ATE337093T1 (enExample)
CA (1) CA2364146C (enExample)
DE (1) DE60030306T2 (enExample)
ES (1) ES2269093T3 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224976B1 (en) 2000-12-28 2006-08-23 F. Hoffmann-La Roche Ag Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge
EP1419820A1 (en) * 2002-11-14 2004-05-19 F. Hoffmann-La Roche Ag Method, system and reaction vessel for processing a biological sample contained in a liquid
EP1419821A1 (en) * 2002-11-14 2004-05-19 F. Hoffmann-La Roche Ag Method, system and reaction vessel for processing a biological sample contained in a liquid
JP3920223B2 (ja) * 2003-01-07 2007-05-30 日本碍子株式会社 反応性チップと、このチップを用いた標的物質の結合検出方法
DE602004009775T2 (de) 2004-07-02 2008-08-28 Roche Diagnostics Gmbh Vorrichtung zur zuverlässige Analyse
US20080226502A1 (en) * 2005-07-07 2008-09-18 Jacques Jonsmann Microfluidic Methods and Support Instruments
WO2008012550A2 (en) 2006-07-28 2008-01-31 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
EP2101917A1 (en) 2007-01-10 2009-09-23 Scandinavian Micro Biodevices A/S A microfluidic device and a microfluidic system and a method of performing a test
WO2008139415A1 (en) * 2007-05-14 2008-11-20 Koninklijke Philips Electronics N.V. Microfluidic device and method of operating a microfluidic device
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
JPWO2010001636A1 (ja) * 2008-07-01 2011-12-15 日本碍子株式会社 Dnaアレイ
JP5867668B2 (ja) 2010-12-01 2016-02-24 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル方法
JP5896100B2 (ja) * 2011-03-01 2016-03-30 セイコーエプソン株式会社 熱サイクル装置
JP2013208066A (ja) 2012-03-30 2013-10-10 Seiko Epson Corp 熱サイクル装置及び熱サイクル装置の制御方法
JP5971463B2 (ja) 2012-03-30 2016-08-17 セイコーエプソン株式会社 熱サイクル装置及び熱サイクル装置の制御方法
JP5967361B2 (ja) 2012-06-06 2016-08-10 セイコーエプソン株式会社 熱サイクル装置
JP2013252091A (ja) * 2012-06-06 2013-12-19 Seiko Epson Corp 熱サイクル装置
JP2015154722A (ja) 2014-02-20 2015-08-27 セイコーエプソン株式会社 核酸増幅反応容器及び核酸増幅反応装置
EP3151965B1 (en) 2014-06-04 2021-02-24 Edan Instruments, Inc. Sample collection and analysis devices
CN109794308B (zh) * 2017-11-17 2021-05-04 长春长光华大智造测序设备有限公司 一种生物芯片承载架
CN113559753B (zh) * 2021-09-23 2021-12-03 启锰生物科技(江苏)有限公司 一种佐剂疫苗用的检测组件

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5133937A (en) * 1989-06-01 1992-07-28 Iniziative Marittime, 1991 S.R.L. Analysis system having a removable reaction cartridge and temperature control
EP0695941B1 (en) * 1994-06-08 2002-07-31 Affymetrix, Inc. Method and apparatus for packaging a chip
US6071394A (en) * 1996-09-06 2000-06-06 Nanogen, Inc. Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis
US5959098A (en) * 1996-04-17 1999-09-28 Affymetrix, Inc. Substrate preparation process
US5922604A (en) * 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
CN1224462C (zh) 1997-07-18 2005-10-26 阿诺德有限公司 把材料粉碎成细小颗粒
JP3938982B2 (ja) * 1997-08-29 2007-06-27 オリンパス株式会社 Dnaキャピラリィ
US5961930A (en) * 1997-10-15 1999-10-05 Eastman Kodak Company Integrated micro-ceramic chemical plant with insertable reaction chambers and micro-filters
US6087102A (en) * 1998-01-07 2000-07-11 Clontech Laboratories, Inc. Polymeric arrays and methods for their use in binding assays
US6426184B1 (en) 1998-02-11 2002-07-30 The Regents Of The University Of Michigan Method and apparatus for chemical and biochemical reactions using photo-generated reagents
FR2806165B1 (fr) * 2000-03-09 2003-01-17 Genomic Sa Automate pour l'analyse biologique
JP3871846B2 (ja) * 2000-03-10 2007-01-24 日立ソフトウエアエンジニアリング株式会社 ハイブリダイゼーション反応検出方法及び検出装置
WO2002042775A2 (en) 2000-11-27 2002-05-30 Genevention L.L.C. Clinically intelligent diagnostic devices and methods
ES2232407T3 (es) * 2000-12-28 2005-06-01 F. Hoffmann-La Roche Ag Metodo para el procesado de una muestra de acido nucleico mediante la oscilacion de un segmento de una pared de un cartucho, un sistema y un cartucho para realizar dicho metodo.
EP1224976B1 (en) 2000-12-28 2006-08-23 F. Hoffmann-La Roche Ag Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge

Also Published As

Publication number Publication date
DE60030306T2 (de) 2007-08-30
DE60030306D1 (de) 2006-10-05
US20020155475A1 (en) 2002-10-24
US6921639B2 (en) 2005-07-26
JP3970023B2 (ja) 2007-09-05
EP1623762A3 (en) 2014-05-21
US20050170496A1 (en) 2005-08-04
CA2364146A1 (en) 2002-06-28
JP2007010684A (ja) 2007-01-18
EP1224976B1 (en) 2006-08-23
EP1623762A2 (en) 2006-02-08
US7435575B2 (en) 2008-10-14
CA2364146C (en) 2010-09-14
JP4512573B2 (ja) 2010-07-28
ATE337093T1 (de) 2006-09-15
EP1224976A1 (en) 2002-07-24
JP2002257830A (ja) 2002-09-11

Similar Documents

Publication Publication Date Title
ES2269093T3 (es) Metodo, sistema y cartucho para el procedimiento de una muestra de acido nucleico mediante la oscilacion del cartucho.
CN112368077B (zh) 流动池装置及其用途
JP4754746B2 (ja) 棒状担体およびこれを具備するシリンダー反応容器
US7410617B2 (en) Sample handling plate
JP4824312B2 (ja) 微小孔物質、被分析物の局在化及び定量の方法、並びに被分析物の局在化及び定量用物品
ES2365305T3 (es) Montaje para reacción química con intercambio de calor e interrogación óptica, y recipiente de reacción.
ES2468290T3 (es) Aparato y método para manipular fluidos para análisis
ES2261781T3 (es) Dispositivo para sujetar un soporte de bibliotecas de sustancias.
JP6449017B2 (ja) 直動型反応処理装置およびその方法
US20030152927A1 (en) Closed substrate platforms suitable for analysis of biomolecules
ES2232407T3 (es) Metodo para el procesado de una muestra de acido nucleico mediante la oscilacion de un segmento de una pared de un cartucho, un sistema y un cartucho para realizar dicho metodo.
EP1385006A2 (en) System and cartridge for processing a biological sample
BG63763B1 (bg) Диск за лабораторни изследвания и метод за провеждане на оптичен контрол на проба
ES2756124T3 (es) Dispositivo de ensayo que tiene un puerto de lavado
ES2916498T3 (es) Método para identificar una secuencia de nucleótidos en una especie desconocida de ácido nucleico; y dispositivo para llevar a cabo el método
CN113557090B (zh) 成分进入流体的精确递送
JP4351028B2 (ja) 液体に含まれている生物学的試料を処理する方法、システム及び反応容器
ES2207539T3 (es) Dispositivo de analisis con un biochip.
EP3279671B1 (en) Analysis chip
ES2323316T3 (es) Aparato para medir el comportamiento de coagulacion de fluidos corporales.
JP2002303627A (ja) Dnaマイクロアレイ製作方法及びdnaマイクロアレイ容器
JP2012233752A (ja) 分析チップ