ATE337093T1 - Verfahren, system und patrone zur verarbeitung einer nukleinsäure-probe durch oszillation der patrone - Google Patents
Verfahren, system und patrone zur verarbeitung einer nukleinsäure-probe durch oszillation der patroneInfo
- Publication number
- ATE337093T1 ATE337093T1 AT00811253T AT00811253T ATE337093T1 AT E337093 T1 ATE337093 T1 AT E337093T1 AT 00811253 T AT00811253 T AT 00811253T AT 00811253 T AT00811253 T AT 00811253T AT E337093 T1 ATE337093 T1 AT E337093T1
- Authority
- AT
- Austria
- Prior art keywords
- cartridge
- nucleic acid
- processing
- acid sample
- oscillation
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 230000010355 oscillation Effects 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/10—Mixers with shaking, oscillating, or vibrating mechanisms with a mixing receptacle rotating alternately in opposite directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/201—Holders therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
- B01L9/527—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for microfluidic devices, e.g. used for lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0457—Moving fluids with specific forces or mechanical means specific forces passive flow or gravitation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00524—Mixing by agitating sample carrier
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/924—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis using nanostructure as support of dna analysis
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00811253A EP1224976B1 (en) | 2000-12-28 | 2000-12-28 | Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE337093T1 true ATE337093T1 (de) | 2006-09-15 |
Family
ID=8175115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00811253T ATE337093T1 (de) | 2000-12-28 | 2000-12-28 | Verfahren, system und patrone zur verarbeitung einer nukleinsäure-probe durch oszillation der patrone |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6921639B2 (enExample) |
| EP (2) | EP1224976B1 (enExample) |
| JP (2) | JP3970023B2 (enExample) |
| AT (1) | ATE337093T1 (enExample) |
| CA (1) | CA2364146C (enExample) |
| DE (1) | DE60030306T2 (enExample) |
| ES (1) | ES2269093T3 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1224976B1 (en) | 2000-12-28 | 2006-08-23 | F. Hoffmann-La Roche Ag | Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge |
| EP1419820A1 (en) * | 2002-11-14 | 2004-05-19 | F. Hoffmann-La Roche Ag | Method, system and reaction vessel for processing a biological sample contained in a liquid |
| EP1419821A1 (en) * | 2002-11-14 | 2004-05-19 | F. Hoffmann-La Roche Ag | Method, system and reaction vessel for processing a biological sample contained in a liquid |
| JP3920223B2 (ja) * | 2003-01-07 | 2007-05-30 | 日本碍子株式会社 | 反応性チップと、このチップを用いた標的物質の結合検出方法 |
| DE602004009775T2 (de) | 2004-07-02 | 2008-08-28 | Roche Diagnostics Gmbh | Vorrichtung zur zuverlässige Analyse |
| US20080226502A1 (en) * | 2005-07-07 | 2008-09-18 | Jacques Jonsmann | Microfluidic Methods and Support Instruments |
| WO2008012550A2 (en) | 2006-07-28 | 2008-01-31 | Diagnostics For The Real World, Ltd. | Device, system and method for processing a sample |
| EP2101917A1 (en) | 2007-01-10 | 2009-09-23 | Scandinavian Micro Biodevices A/S | A microfluidic device and a microfluidic system and a method of performing a test |
| WO2008139415A1 (en) * | 2007-05-14 | 2008-11-20 | Koninklijke Philips Electronics N.V. | Microfluidic device and method of operating a microfluidic device |
| WO2009024773A1 (en) | 2007-08-17 | 2009-02-26 | Diagnostics For The Real World, Ltd | Device, system and method for processing a sample |
| JPWO2010001636A1 (ja) * | 2008-07-01 | 2011-12-15 | 日本碍子株式会社 | Ｄｎａアレイ |
| JP5867668B2 (ja) | 2010-12-01 | 2016-02-24 | セイコーエプソン株式会社 | 熱サイクル装置及び熱サイクル方法 |
| JP5896100B2 (ja) * | 2011-03-01 | 2016-03-30 | セイコーエプソン株式会社 | 熱サイクル装置 |
| JP2013208066A (ja) | 2012-03-30 | 2013-10-10 | Seiko Epson Corp | 熱サイクル装置及び熱サイクル装置の制御方法 |
| JP5971463B2 (ja) | 2012-03-30 | 2016-08-17 | セイコーエプソン株式会社 | 熱サイクル装置及び熱サイクル装置の制御方法 |
| JP5967361B2 (ja) | 2012-06-06 | 2016-08-10 | セイコーエプソン株式会社 | 熱サイクル装置 |
| JP2013252091A (ja) * | 2012-06-06 | 2013-12-19 | Seiko Epson Corp | 熱サイクル装置 |
| JP2015154722A (ja) | 2014-02-20 | 2015-08-27 | セイコーエプソン株式会社 | 核酸増幅反応容器及び核酸増幅反応装置 |
| EP3151965B1 (en) | 2014-06-04 | 2021-02-24 | Edan Instruments, Inc. | Sample collection and analysis devices |
| CN109794308B (zh) * | 2017-11-17 | 2021-05-04 | 长春长光华大智造测序设备有限公司 | 一种生物芯片承载架 |
| CN113559753B (zh) * | 2021-09-23 | 2021-12-03 | 启锰生物科技(江苏)有限公司 | 一种佐剂疫苗用的检测组件 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5133937A (en) * | 1989-06-01 | 1992-07-28 | Iniziative Marittime, 1991 S.R.L. | Analysis system having a removable reaction cartridge and temperature control |
| EP0695941B1 (en) * | 1994-06-08 | 2002-07-31 | Affymetrix, Inc. | Method and apparatus for packaging a chip |
| US6071394A (en) * | 1996-09-06 | 2000-06-06 | Nanogen, Inc. | Channel-less separation of bioparticles on a bioelectronic chip by dielectrophoresis |
| US5959098A (en) * | 1996-04-17 | 1999-09-28 | Affymetrix, Inc. | Substrate preparation process |
| US5922604A (en) * | 1997-06-05 | 1999-07-13 | Gene Tec Corporation | Thin reaction chambers for containing and handling liquid microvolumes |
| CN1224462C (zh) | 1997-07-18 | 2005-10-26 | 阿诺德有限公司 | 把材料粉碎成细小颗粒 |
| JP3938982B2 (ja) * | 1997-08-29 | 2007-06-27 | オリンパス株式会社 | Ｄｎａキャピラリィ |
| US5961930A (en) * | 1997-10-15 | 1999-10-05 | Eastman Kodak Company | Integrated micro-ceramic chemical plant with insertable reaction chambers and micro-filters |
| US6087102A (en) * | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| US6426184B1 (en) | 1998-02-11 | 2002-07-30 | The Regents Of The University Of Michigan | Method and apparatus for chemical and biochemical reactions using photo-generated reagents |
| FR2806165B1 (fr) * | 2000-03-09 | 2003-01-17 | Genomic Sa | Automate pour l'analyse biologique |
| JP3871846B2 (ja) * | 2000-03-10 | 2007-01-24 | 日立ソフトウエアエンジニアリング株式会社 | ハイブリダイゼーション反応検出方法及び検出装置 |
| WO2002042775A2 (en) | 2000-11-27 | 2002-05-30 | Genevention L.L.C. | Clinically intelligent diagnostic devices and methods |
| ES2232407T3 (es) * | 2000-12-28 | 2005-06-01 | F. Hoffmann-La Roche Ag | Metodo para el procesado de una muestra de acido nucleico mediante la oscilacion de un segmento de una pared de un cartucho, un sistema y un cartucho para realizar dicho metodo. |
| EP1224976B1 (en) | 2000-12-28 | 2006-08-23 | F. Hoffmann-La Roche Ag | Method, system and cartridge for processing a nucleic acid sample by oscillating the cartridge |
-
2000
- 2000-12-28 EP EP00811253A patent/EP1224976B1/en not_active Expired - Lifetime
- 2000-12-28 AT AT00811253T patent/ATE337093T1/de active
- 2000-12-28 DE DE60030306T patent/DE60030306T2/de not_active Expired - Lifetime
- 2000-12-28 ES ES00811253T patent/ES2269093T3/es not_active Expired - Lifetime
- 2000-12-28 EP EP05022568.9A patent/EP1623762A3/en not_active Withdrawn
-
2001
- 2001-11-30 CA CA2364146A patent/CA2364146C/en not_active Expired - Fee Related
- 2001-12-27 JP JP2001397708A patent/JP3970023B2/ja not_active Expired - Fee Related
- 2001-12-27 US US10/033,424 patent/US6921639B2/en not_active Expired - Fee Related
-
2005
- 2005-04-04 US US11/099,107 patent/US7435575B2/en not_active Expired - Fee Related
-
2006
- 2006-09-11 JP JP2006245035A patent/JP4512573B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60030306T2 (de) | 2007-08-30 |
| DE60030306D1 (de) | 2006-10-05 |
| US20020155475A1 (en) | 2002-10-24 |
| US6921639B2 (en) | 2005-07-26 |
| JP3970023B2 (ja) | 2007-09-05 |
| EP1623762A3 (en) | 2014-05-21 |
| US20050170496A1 (en) | 2005-08-04 |
| CA2364146A1 (en) | 2002-06-28 |
| JP2007010684A (ja) | 2007-01-18 |
| EP1224976B1 (en) | 2006-08-23 |
| EP1623762A2 (en) | 2006-02-08 |
| US7435575B2 (en) | 2008-10-14 |
| CA2364146C (en) | 2010-09-14 |
| JP4512573B2 (ja) | 2010-07-28 |
| ES2269093T3 (es) | 2007-04-01 |
| EP1224976A1 (en) | 2002-07-24 |
| JP2002257830A (ja) | 2002-09-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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