ES2143848T3 - Metodos para detectar la fijacion de una pareja de ligandos con sensibilidad mejorada. - Google Patents

Metodos para detectar la fijacion de una pareja de ligandos con sensibilidad mejorada.

Info

Publication number
ES2143848T3
ES2143848T3 ES97903074T ES97903074T ES2143848T3 ES 2143848 T3 ES2143848 T3 ES 2143848T3 ES 97903074 T ES97903074 T ES 97903074T ES 97903074 T ES97903074 T ES 97903074T ES 2143848 T3 ES2143848 T3 ES 2143848T3
Authority
ES
Spain
Prior art keywords
detect
leagues
couple
methods
elements
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97903074T
Other languages
English (en)
Spanish (es)
Inventor
Ness Jeffrey Van
John C Tabone
J Jeffry Howbert
John T Mulligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rapigene Inc
Original Assignee
Rapigene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rapigene Inc filed Critical Rapigene Inc
Application granted granted Critical
Publication of ES2143848T3 publication Critical patent/ES2143848T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/167—Mass label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/627—Detection means characterised by use of a special device being a mass spectrometer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES97903074T 1996-01-23 1997-01-23 Metodos para detectar la fijacion de una pareja de ligandos con sensibilidad mejorada. Expired - Lifetime ES2143848T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1043696P 1996-01-23 1996-01-23
US1540296P 1996-03-21 1996-03-21

Publications (1)

Publication Number Publication Date
ES2143848T3 true ES2143848T3 (es) 2000-05-16

Family

ID=26681173

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97903074T Expired - Lifetime ES2143848T3 (es) 1996-01-23 1997-01-23 Metodos para detectar la fijacion de una pareja de ligandos con sensibilidad mejorada.

Country Status (17)

Country Link
EP (1) EP0850320B1 (enExample)
JP (2) JP2000507091A (enExample)
KR (2) KR100538669B1 (enExample)
CN (2) CN1159452C (enExample)
AT (1) ATE187501T1 (enExample)
AU (1) AU717330B2 (enExample)
BR (1) BR9707060A (enExample)
CA (1) CA2243989A1 (enExample)
CZ (1) CZ218398A3 (enExample)
DE (1) DE69700902T2 (enExample)
ES (1) ES2143848T3 (enExample)
GR (1) GR3032843T3 (enExample)
HU (1) HUP9900459A3 (enExample)
NZ (1) NZ331042A (enExample)
PL (1) PL328272A1 (enExample)
PT (1) PT850320E (enExample)
WO (1) WO1997027327A2 (enExample)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US6401267B1 (en) 1993-09-27 2002-06-11 Radoje Drmanac Methods and compositions for efficient nucleic acid sequencing
CZ228598A3 (cs) * 1996-01-23 1998-12-16 Rapigene, Inc. Způsoby a kompozice pro analyzování molekul nukleových kyselin za použití postupu třídění
US6051378A (en) * 1996-03-04 2000-04-18 Genetrace Systems Inc. Methods of screening nucleic acids using mass spectrometry
US5965363A (en) * 1996-09-19 1999-10-12 Genetrace Systems Inc. Methods of preparing nucleic acids for mass spectrometric analysis
US6635452B1 (en) * 1996-12-10 2003-10-21 Sequenom Inc. Releasable nonvolatile mass label molecules
JP2001523952A (ja) * 1997-02-24 2001-11-27 ティーエム テクノロジーズ，インク． アンチセンス・オリゴヌクレオチドを選択するプロセス
ATE335845T1 (de) * 1997-05-16 2006-09-15 Exact Sciences Corp Elektrophoretische analyse von molekülen mit immobilisierten sonden
ATE240408T1 (de) * 1997-07-22 2003-05-15 Qiagen Genomics Inc Verfahren und verbindungen zur analysierung von nukleinsaeuren durch massenspektrometrie
US6365731B1 (en) 1997-08-06 2002-04-02 Ambion, Inc. Stripping nucleic acids with iodine and sodium thiosulfate
WO1999007889A1 (en) * 1997-08-05 1999-02-18 Ambion, Inc. Methods and compositions for stripping nucleic acids
US5968822A (en) * 1997-09-02 1999-10-19 Pecker; Iris Polynucleotide encoding a polypeptide having heparanase activity and expression of same in transduced cells
CA2309384A1 (en) 1997-11-06 1999-05-20 Mosaic Technologies Multiple sequential polynucleotide displacement reactions for signal amplification and processing
GB9823646D0 (en) * 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry
GB9815166D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB9815164D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
US6104028A (en) * 1998-05-29 2000-08-15 Genetrace Systems Inc. Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
GB9812596D0 (en) * 1998-06-11 1998-08-12 Amersham Pharm Biotech Uk Ltd Energy transfer assay method
WO2000020643A1 (en) 1998-10-05 2000-04-13 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
CA2384191A1 (en) * 1999-08-31 2001-03-08 Benjamin M. Skead Enantiomerically-enriched compounds having photocleavable bond(s) and methods related thereto
DE19945351C2 (de) * 1999-09-22 2002-04-18 Lohmann Therapie Syst Lts Verfahren zum Auffinden und zur Isolierung pharmakologisch wirksamer Verbindungen aus Substanzgemischen
WO2001055454A1 (en) 2000-01-28 2001-08-02 Althea Technologies, Inc. Methods for analysis of gene expression
US7771929B2 (en) 2000-04-28 2010-08-10 Monogram Biosciences, Inc. Tag library compounds, compositions, kits and methods of use
US7160735B2 (en) 2000-04-28 2007-01-09 Monogram Biosciences, Inc. Tagged microparticle compositions and methods
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US6716634B1 (en) 2000-05-31 2004-04-06 Agilent Technologies, Inc. Increasing ionization efficiency in mass spectrometry
US6548252B1 (en) 2000-10-13 2003-04-15 Esa, Inc. Detection of DNA damage
AU2002305658A1 (en) 2001-05-21 2002-12-03 Aclara Biosciences, Inc. Analyzing phosphorylated proteins
JP2005505749A (ja) 2001-05-21 2005-02-24 アクララ バイオサイエンシーズ， インコーポレイテッド タンパク質を分析するための方法および組成物
AU2002344221A1 (en) 2001-05-26 2002-12-09 Aclara Biosciences, Inc. Catalytic amplification of multiplexed assay signals
DE10142643A1 (de) * 2001-08-31 2003-04-24 Clondiag Chip Tech Gmbh Detektion von Wechselwirkungen auf Sonden-Arrays
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
US7402397B2 (en) 2002-05-21 2008-07-22 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
US20040229294A1 (en) 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
JP2006501817A (ja) * 2002-06-03 2006-01-19 パムジーン ビー．ブイ． 新規高密度アレイおよび検体分析方法
GB0306756D0 (en) * 2003-03-24 2003-04-30 Xzillion Gmbh & Co Kg Mass labels
US7250388B2 (en) * 2003-11-07 2007-07-31 Hewlett-Packard Development Company, L.P. Medium for chromatographic separations
FR2868067B1 (fr) * 2004-03-23 2006-06-23 Neomps Sa Derives d'amino-acides utiles comme agents de liaison a un support solide, leur procede de preparation et leur application a lasynthese de peptides
AU2005280528B2 (en) 2004-07-30 2010-12-23 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
EP2322920B1 (en) * 2005-06-07 2014-12-10 Centre National de la Recherche Scientifique (CNRS) MALDI tissue imaging using conjugates cleavable by fast fragmentation
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US7605916B2 (en) * 2006-09-21 2009-10-20 Intel Corporation Online analyte detection by surface enhanced Raman scattering (SERS)
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
GB0809488D0 (en) 2008-05-23 2008-07-02 Electrophoretics Ltd Mass spectrometric analysis
GB0811574D0 (en) * 2008-06-24 2008-07-30 Trillion Genomics Ltd Characterising planar samples by mass spectrometry
GB0905438D0 (en) * 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
US20100297778A1 (en) * 2009-05-20 2010-11-25 Abbott Laboratories Conjugate Having Cleavable Linking Agent
GB0921665D0 (en) 2009-12-10 2010-01-27 Trillion Genomics Ltd Phobes
EP2588144B1 (en) 2010-07-02 2018-05-09 Ventana Medical Systems, Inc. Detecting targets using mass tags and mass spectrometry
EP2754496A3 (en) 2010-07-23 2017-08-02 Beckman Coulter, Inc. System Or Method Of Including Analytical Units
US9637773B2 (en) 2011-01-13 2017-05-02 Enzo Life Sciences, Inc. Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties
ES2729283T3 (es) 2011-11-07 2019-10-31 Beckman Coulter Inc Sistema de centrífuga y flujo de trabajo
EP3373015A1 (en) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotter system and workflow
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
EP2776847A1 (en) 2011-11-07 2014-09-17 Beckman Coulter, Inc. Magnetic damping for specimen transport system
BR112014010955A2 (pt) 2011-11-07 2017-06-06 Beckman Coulter Inc sistema e método para processar amostras
BR112014011048A2 (pt) 2011-11-07 2017-05-02 Beckman Coulter Inc braço robótico
US8927732B2 (en) * 2012-03-30 2015-01-06 General Electric Company Biotin stannane for HPLC-free radioiodination
GB201322567D0 (en) 2013-12-19 2014-02-05 Electrophoretics Ltd Mass labels
CN103792219A (zh) * 2014-02-27 2014-05-14 厦门大学 红肉蜜柚光谱鉴别法
WO2017127670A1 (en) * 2016-01-22 2017-07-27 Purdue Research Foundation Charged mass labeling system
US10814319B2 (en) 2016-09-30 2020-10-27 Board Of Regents, University Of Texas System Functionalized polyolefin capillaries for open tubular ion chromatography
CN108490093A (zh) * 2018-03-29 2018-09-04 曲阜师范大学 一种开关型硫醇荧光标记试剂的荧光检测应用及其合成方法
CN112240915B (zh) * 2019-07-19 2022-08-12 杭州盛弗泰新材料科技有限公司 一种5-氨基-1h-1，2，4-三氮唑-3-羧酸的高效液相色谱检测方法
WO2021092795A1 (zh) * 2019-11-13 2021-05-20 李峰 核酸检测方法及装置
CN115667217A (zh) 2020-05-19 2023-01-31 赛本爱尔兰有限公司 氘化的色胺衍生物和使用方法
CN112816578B (zh) * 2020-12-30 2021-09-24 上海市农业科学院 一种含氨基小分子蘑菇毒素的检测方法以及一种试剂盒
CN112881491A (zh) * 2021-02-05 2021-06-01 深圳大学 一种生物传感器电极的制备方法和葡萄糖生物传感器
CN113548981B (zh) * 2021-08-05 2023-04-28 齐鲁工业大学 三苯胺酚类化合物及其制备方法与其检测色氨酸的应用
EP4444904A1 (en) * 2021-12-09 2024-10-16 F. Hoffmann-La Roche AG Mass based detection of pcr amplicons
CN116496335B (zh) * 2023-03-21 2024-03-08 中国药科大学 一种修饰核苷酸及其应用
CN117535045B (zh) * 2023-07-12 2024-05-31 中国热带农业科学院分析测试中心 一种痕量噻虫嗪检测用Zn-MOF@Au NPS/DNA适配体荧光探针及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709016A (en) * 1982-02-01 1987-11-24 Northeastern University Molecular analytical release tags and their use in chemical analysis
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
FI80476C (fi) * 1987-10-09 1990-06-11 Orion Yhtymae Oy Foerbaettrat hybridisationsfoerfarande, vid foerfarandet anvaent redskap och reagensfoerpackning.
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
DK220890D0 (da) * 1990-09-14 1990-09-14 Ole Buchardt Fremgangsmaade til fremstilling af c-terminalt amiderede peptider
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
JPH0723800A (ja) * 1993-07-08 1995-01-27 Tanabe Seiyaku Co Ltd 核酸の検出方法
GB9315847D0 (en) * 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
CZ228598A3 (cs) * 1996-01-23 1998-12-16 Rapigene, Inc. Způsoby a kompozice pro analyzování molekul nukleových kyselin za použití postupu třídění
AU717435B2 (en) * 1996-01-23 2000-03-23 Qiagen Genomics, Inc. Methods and compositions for determining the sequence of nucleic acid molecules

Also Published As

Publication number Publication date
CN1159452C (zh) 2004-07-28
AU717330B2 (en) 2000-03-23
PL328272A1 (en) 1999-01-18
EP0850320A2 (en) 1998-07-01
BR9707060A (pt) 1999-12-28
CZ218398A3 (cs) 1998-12-16
DE69700902D1 (de) 2000-01-13
HUP9900459A2 (hu) 1999-06-28
PT850320E (pt) 2000-05-31
KR100473903B1 (ko) 2005-09-30
KR19990081923A (ko) 1999-11-15
JP2000507091A (ja) 2000-06-13
HUP9900459A3 (en) 1999-11-29
AU1707997A (en) 1997-08-20
CN1515541A (zh) 2004-07-28
ATE187501T1 (de) 1999-12-15
KR100538669B1 (ko) 2005-12-26
DE69700902T2 (de) 2000-07-20
JP2008220370A (ja) 2008-09-25
WO1997027327A2 (en) 1997-07-31
EP0850320B1 (en) 1999-12-08
CA2243989A1 (en) 1997-07-31
WO1997027327A3 (en) 1997-11-20
CN1212019A (zh) 1999-03-24
GR3032843T3 (en) 2000-07-31
NZ331042A (en) 1999-10-28
KR20040081811A (ko) 2004-09-22

Similar Documents

Publication Publication Date Title
ES2143848T3 (es) Metodos para detectar la fijacion de una pareja de ligandos con sensibilidad mejorada.
AR015796A1 (es) Kit para la deteccion de helicobacter pylori
ES2153336T1 (es) Medidor biosensor con clave de memoria conectable.
JPS55156840A (en) Specimen detector
AU1775188A (en) Body fluid sample collection tube composite
ATE302407T1 (de) System zur überwachung des blutglucosespiegels
DK38186D0 (da) Indretning til separation af den lettere del fra den tungere del af envaeskeproeve
GR1000779B (el) Τεχνικες διαχωρισμου αιματος και ανιχνευσεως αναλυτη.
ES2036667T3 (es) Metodo de ensayo que utiliza particulas con un fluorescedor asociado.
ES2191175T3 (es) Procedimiento para la captacion del estado de un organismo por medicion de peptidos.
ES2040032T3 (es) Dispositivo para medir un desplazamiento relativo.
ES8608169A1 (es) Un metodo de detectar en una muestra un analito
ES2114066T3 (es) Eliminacion de resultados de ensayo falso negativos en la deteccion de acido nucleico.
DK245882A (da) Fremgangsmaade og apparat til maaling af partiklers stoerrelse
JPS5441191A (en) Glucose-oxygen sensitive electrode
DK166285A (da) Fremgangsmaade til udvinding af chitin fra chitinkilder, hvori det findes sammen med eller bundet til proteinstoffer
ES2194116T3 (es) Procedimiento para detectar anticuerpos antipolimero y kit de prueba de diagnostico para uso como ayuda al diagnostico de las enfermedades relacionadas con silicona.
GB8824712D0 (en) Luminescence monitoring apparatus & method
ATE142335T1 (de) Vorrichtung zur durchführung mehrerer gleichzeitiger messungen electrochemilumineszenter phänomene
ATE20498T1 (de) Verfahren zur bestimmung des ph-wertes im innern einer zelle.
JPS567539A (en) Monitor for optical fiber joint
NO179344C (no) Fremgangsmåte for undersökelse av en blodpröve og måling av polarisert fluorescensutstråling
ES2081900T3 (es) Composiciones de ensayo de barbituratos y metodos.
ES2100357T3 (es) Aparato para la manipulacion de membranas de transferencia electroforetica y para la deteccion quimioluminiscente de manchas contenidas en las mismas, asi como procedimientos en los que se emplea dicho aparato.
ES2173168T3 (es) Reactivo para ensayar la creatinaquinasa.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 850320

Country of ref document: ES