BR9707060A - Métodos e composições para detectar o ligamento de par ligante usando indicador não-fluorescente. - Google Patents
Métodos e composições para detectar o ligamento de par ligante usando indicador não-fluorescente.Info
- Publication number
- BR9707060A BR9707060A BR9707060-2A BR9707060A BR9707060A BR 9707060 A BR9707060 A BR 9707060A BR 9707060 A BR9707060 A BR 9707060A BR 9707060 A BR9707060 A BR 9707060A
- Authority
- BR
- Brazil
- Prior art keywords
- ligament
- methods
- indicator
- compositions
- ligand pair
- Prior art date
Links
- 210000003041 ligament Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000003269 fluorescent indicator Substances 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000004313 potentiometry Methods 0.000 abstract 2
- 238000004611 spectroscopical analysis Methods 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/167—Mass label
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
- C12Q2565/60—Detection means characterised by use of a special device
- C12Q2565/627—Detection means characterised by use of a special device being a mass spectrometer
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Luminescent Compositions (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
''MéTODOS E COMPOSIçõES PARA DETECTAR O LIGAMENTO DE PAR LIGANTE USANDO INDICADOR NãO-FLUORESCENTE''. Proporciona-se métodos para detectar o ligamento de um primeiro membro a um segundo membro de um par ligante, compreendendo as etapas de (a) combinar um conjunto de primeiros membros marcados com uma amostra biológica que pode conter um ou mais segundos membros, sob condições e por um tempo suficientes para permitir o ligamento de um primeiro membro a um segundo membro, em que dito indicador é correlacionado com um primeiro membro em particular e detectável por espectrometria não-fluorescente, ou potenciometria; (b) separar o primeiro e o segundo membros ligados dos membros não-ligados; (c) clivar o indicador do primeiro membro marcado; e (d) detectar o indicador por espectrometria não-fluorescente, ou potenciometria, e daí detectar o ligamento do primeiro membro ao segundo membro.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1043696P | 1996-01-23 | 1996-01-23 | |
US1540296P | 1996-03-21 | 1996-03-21 | |
PCT/US1997/001070 WO1997027327A2 (en) | 1996-01-23 | 1997-01-23 | Methods and compositions for detecting binding of ligand pair using non-fluorescent label |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9707060A true BR9707060A (pt) | 1999-12-28 |
Family
ID=26681173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9707060-2A BR9707060A (pt) | 1996-01-23 | 1997-01-23 | Métodos e composições para detectar o ligamento de par ligante usando indicador não-fluorescente. |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0850320B1 (pt) |
JP (2) | JP2000507091A (pt) |
KR (2) | KR100473903B1 (pt) |
CN (2) | CN1159452C (pt) |
AT (1) | ATE187501T1 (pt) |
AU (1) | AU717330B2 (pt) |
BR (1) | BR9707060A (pt) |
CA (1) | CA2243989A1 (pt) |
CZ (1) | CZ218398A3 (pt) |
DE (1) | DE69700902T2 (pt) |
ES (1) | ES2143848T3 (pt) |
GR (1) | GR3032843T3 (pt) |
HU (1) | HUP9900459A3 (pt) |
NZ (1) | NZ331042A (pt) |
PL (1) | PL328272A1 (pt) |
PT (1) | PT850320E (pt) |
WO (1) | WO1997027327A2 (pt) |
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CN103792219A (zh) * | 2014-02-27 | 2014-05-14 | 厦门大学 | 红肉蜜柚光谱鉴别法 |
EP4012416A1 (en) * | 2016-01-22 | 2022-06-15 | Purdue Research Foundation | Use of a charged mass labeling system for the detection of target analytes |
US10814319B2 (en) | 2016-09-30 | 2020-10-27 | Board Of Regents, University Of Texas System | Functionalized polyolefin capillaries for open tubular ion chromatography |
CN108490093A (zh) * | 2018-03-29 | 2018-09-04 | 曲阜师范大学 | 一种开关型硫醇荧光标记试剂的荧光检测应用及其合成方法 |
CN112240915B (zh) * | 2019-07-19 | 2022-08-12 | 杭州盛弗泰新材料科技有限公司 | 一种5-氨基-1h-1,2,4-三氮唑-3-羧酸的高效液相色谱检测方法 |
CN114341627A (zh) * | 2019-11-13 | 2022-04-12 | 李峰 | 核酸检测方法及装置 |
KR20230012501A (ko) | 2020-05-19 | 2023-01-26 | 사이빈 아이알엘 리미티드 | 중수소화된 트립타민 유도체 및 사용 방법 |
CN112816578B (zh) * | 2020-12-30 | 2021-09-24 | 上海市农业科学院 | 一种含氨基小分子蘑菇毒素的检测方法以及一种试剂盒 |
CN112881491A (zh) * | 2021-02-05 | 2021-06-01 | 深圳大学 | 一种生物传感器电极的制备方法和葡萄糖生物传感器 |
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1997
- 1997-01-23 AT AT97903074T patent/ATE187501T1/de not_active IP Right Cessation
- 1997-01-23 HU HU9900459A patent/HUP9900459A3/hu unknown
- 1997-01-23 DE DE69700902T patent/DE69700902T2/de not_active Expired - Lifetime
- 1997-01-23 AU AU17079/97A patent/AU717330B2/en not_active Ceased
- 1997-01-23 CN CNB971925542A patent/CN1159452C/zh not_active Expired - Fee Related
- 1997-01-23 PT PT97903074T patent/PT850320E/pt unknown
- 1997-01-23 CN CNA2004100027867A patent/CN1515541A/zh active Pending
- 1997-01-23 CA CA002243989A patent/CA2243989A1/en not_active Abandoned
- 1997-01-23 KR KR10-1998-0705636A patent/KR100473903B1/ko not_active IP Right Cessation
- 1997-01-23 BR BR9707060-2A patent/BR9707060A/pt not_active Application Discontinuation
- 1997-01-23 KR KR10-2004-7013511A patent/KR100538669B1/ko not_active IP Right Cessation
- 1997-01-23 WO PCT/US1997/001070 patent/WO1997027327A2/en not_active Application Discontinuation
- 1997-01-23 CZ CZ982183A patent/CZ218398A3/cs unknown
- 1997-01-23 PL PL97328272A patent/PL328272A1/xx unknown
- 1997-01-23 JP JP9526988A patent/JP2000507091A/ja not_active Withdrawn
- 1997-01-23 EP EP97903074A patent/EP0850320B1/en not_active Expired - Lifetime
- 1997-01-23 NZ NZ331042A patent/NZ331042A/en unknown
- 1997-01-23 ES ES97903074T patent/ES2143848T3/es not_active Expired - Lifetime
-
2000
- 2000-03-03 GR GR20000400535T patent/GR3032843T3/el not_active IP Right Cessation
-
2008
- 2008-03-04 JP JP2008054174A patent/JP2008220370A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ATE187501T1 (de) | 1999-12-15 |
CN1515541A (zh) | 2004-07-28 |
JP2008220370A (ja) | 2008-09-25 |
KR100473903B1 (ko) | 2005-09-30 |
AU717330B2 (en) | 2000-03-23 |
WO1997027327A2 (en) | 1997-07-31 |
KR19990081923A (ko) | 1999-11-15 |
EP0850320A2 (en) | 1998-07-01 |
HUP9900459A2 (hu) | 1999-06-28 |
CZ218398A3 (cs) | 1998-12-16 |
HUP9900459A3 (en) | 1999-11-29 |
CN1159452C (zh) | 2004-07-28 |
NZ331042A (en) | 1999-10-28 |
ES2143848T3 (es) | 2000-05-16 |
DE69700902D1 (de) | 2000-01-13 |
PT850320E (pt) | 2000-05-31 |
CN1212019A (zh) | 1999-03-24 |
KR20040081811A (ko) | 2004-09-22 |
EP0850320B1 (en) | 1999-12-08 |
PL328272A1 (en) | 1999-01-18 |
GR3032843T3 (en) | 2000-07-31 |
WO1997027327A3 (en) | 1997-11-20 |
CA2243989A1 (en) | 1997-07-31 |
KR100538669B1 (ko) | 2005-12-26 |
DE69700902T2 (de) | 2000-07-20 |
AU1707997A (en) | 1997-08-20 |
JP2000507091A (ja) | 2000-06-13 |
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