ES2148617T3 - Reactivos perfeccionados para un inmunoensayo de cannabinoides. - Google Patents
Reactivos perfeccionados para un inmunoensayo de cannabinoides.Info
- Publication number
- ES2148617T3 ES2148617T3 ES96104776T ES96104776T ES2148617T3 ES 2148617 T3 ES2148617 T3 ES 2148617T3 ES 96104776 T ES96104776 T ES 96104776T ES 96104776 T ES96104776 T ES 96104776T ES 2148617 T3 ES2148617 T3 ES 2148617T3
- Authority
- ES
- Spain
- Prior art keywords
- sup
- linear
- branched
- rent
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
LA PRESENTE INVENCION PROPORCIONA: DERIVADOS DE BENZOPIRANO NUEVOS DE FORMULA DONDE R{SUP,1} ES UN GRUPO ALQUILO LINEAL O RAMIFICADO QUE TIENE DE 1 A 9 ATOMOS DE CARBONO; R{SUP,2} Y R{SUP,3} SE SELECCIONAN INDEPENDIENTEMENTE DE UN ALQUILO INFERIOR LINEAL O RAMIFICADO QUE PUEDE SUSTITUIRSE POR UNO O MAS DE LOS SIGUIENTES GRUPOS FUNCIONALES: -OH, -COR{SUP,4}, -NR{SUP,5}R{SUP,6}, -SH, -C(=NH)OR{SUP,7}, -CHO, O =O SIEMPRE QUE AL MENOS UNO DE R{SUP,2} O R{SUP,3} SE SUSTITUYA POR UNO DE LOS GRUPOS FUNCIONALES ANTES DESCRITOS; R{SUP,4} ES -OH O UN GRUPO DE SALIDA; R{SUP,5} Y R{SUP,6} SE SELECCIONAN INDEPENDIENTEMENTE DEL GRUPO QUE INCLUYE H Y ALQUILO INFERIOR LINEAL O RAMIFICADO; R{SUP,7} ES UN ALQUILO BAJO LINEAL O RAMIFICADO; Y A,B, Y C SON INDEPENDIENTEMENTE ENLACES SENCILLOS O DOBLES, SIEMPRE QUE CUANDO B ES UN ENLACE DOBLE, ENTONCES A Y C SEAN ENLACES DOBLES, ANTICUERPOS NUEVOS PRODUCIDOS MEDIANTE LA UTILIZACION DE DICHOS DERIVADOS DE BENZOPIRANO, METODOS PARA PRODUCIR ESTOS ANTICUERPOS E INMUNOENSAYOS QUE UTILIZAN ESTOS ULTIMOS PARA LA DETECCION DE METABOLITOS DE TETRAHIDROCANABINOL EN MUESTRAS DE SANGRE U ORINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/417,331 US5817766A (en) | 1995-04-05 | 1995-04-05 | Reagents for a cannabinoid immunoassay |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2148617T3 true ES2148617T3 (es) | 2000-10-16 |
Family
ID=23653524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96104776T Expired - Lifetime ES2148617T3 (es) | 1995-04-05 | 1996-03-26 | Reactivos perfeccionados para un inmunoensayo de cannabinoides. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5817766A (es) |
EP (1) | EP0736529B1 (es) |
JP (2) | JP4229990B2 (es) |
AT (1) | ATE194339T1 (es) |
CA (1) | CA2172663C (es) |
DE (1) | DE69609108T2 (es) |
ES (1) | ES2148617T3 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2770828B2 (ja) * | 1997-03-21 | 1998-07-02 | 松下電器産業株式会社 | 文書出力装置 |
DE60042004D1 (de) * | 1999-04-28 | 2009-05-28 | Toray Industries | Stoffe zur enternung von cannabinoiden und säulen mit diesen stoffen zur entfernung von cannabinoiden |
US6686209B2 (en) | 2001-03-12 | 2004-02-03 | Lifepoint, Inc. | Reagents for detecting cannabinoids |
EP1499306A4 (en) * | 2002-04-12 | 2007-03-28 | Merck & Co Inc | BICYCLIC AMIDE |
CA2530211C (en) | 2003-07-01 | 2011-10-04 | Eric R. Diebold | Electrochemical affinity biosensor system and methods |
US20060051824A1 (en) * | 2004-09-03 | 2006-03-09 | Haoyun An | Tetrahydrocannabinoid antigens and method of use |
US7465586B2 (en) * | 2004-11-03 | 2008-12-16 | Labone, Inc. | Oral detection test for cannabinoid use |
KR100794515B1 (ko) | 2005-07-12 | 2008-01-16 | 제일약품주식회사 | 항염증 활성을 갖는 크로멘-2-온 모핵 히드록사민 산유도체, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물 |
WO2007008037A1 (en) * | 2005-07-12 | 2007-01-18 | Jeil Pharmaceutical Co., Ltd. | Novel chromen-2-one based hydroxamic acid derivatives having anti-inflammatory activity, the preparation thereof and a composition containing the same for treating inflammatory disease |
US9441033B2 (en) * | 2011-02-14 | 2016-09-13 | Randox Laboratories Limited | Detection of synthetic cannabinoids |
GB201102544D0 (en) * | 2011-02-14 | 2011-03-30 | Randox Lab Ltd | Assay |
US9435817B2 (en) | 2011-02-14 | 2016-09-06 | Randox Laboratories Limited | Detection of synthetic cannabinoids |
US9434687B2 (en) | 2011-02-14 | 2016-09-06 | Randox Laboratories Limited | Detection of synthetic cannabinoids |
US10408786B2 (en) | 2012-06-14 | 2019-09-10 | ChemiSensor, LLP | Distributable chemical sampling and sensing system |
EP2698383B1 (en) * | 2012-08-14 | 2020-11-25 | Randox Laboratories Ltd. | Detection of synthetic Cannabinoids |
EP2698384A1 (en) * | 2012-08-14 | 2014-02-19 | Randox Laboratories Ltd. | Detection of synthetic cannabinoids |
EP2698385A1 (en) * | 2012-08-14 | 2014-02-19 | Randox Laboratories Ltd. | Detection of synthetic cannabinoids |
US9817007B2 (en) * | 2014-03-05 | 2017-11-14 | John Scott Perez | Method and apparatus for real-time detection of human cannabinoid intoxication |
US10308712B2 (en) | 2014-03-27 | 2019-06-04 | Bird Rock Bio, Inc. | Antibodies that bind human cannabinoid 1 (CB1) receptor |
AU2016330471B2 (en) | 2015-09-30 | 2022-09-29 | Bird Rock Bio, Inc. | Antibodies that bind human cannabinoid 1 (CB1) receptor |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2354492A (en) * | 1941-11-26 | 1944-07-25 | Adams Roger | Marihuana active compound |
US4329281A (en) * | 1978-06-05 | 1982-05-11 | Hoffmann-La Roche Inc. | Hapten compositions |
US4438207A (en) * | 1979-09-26 | 1984-03-20 | Hoffmann-La Roche Inc. | Radioimmunoassay for cannabinoids |
US5223441A (en) * | 1986-10-09 | 1993-06-29 | Syntex (U.S.A.) Inc. | Receptors for immune complexes |
US4833073A (en) * | 1987-01-27 | 1989-05-23 | Hoffmann-La Roche Inc. | Immunoassay for tetrahydrocannabinol metabolites |
DE3855490T2 (de) * | 1987-02-17 | 1997-03-27 | Abbott Lab | Fluoreszenz-Polarisationsimmunotest für Tetrahydrocannabinoide |
US5144030A (en) * | 1987-02-17 | 1992-09-01 | Abbott Laboratories | Fluorescene polarization immunoassay for tetrahydrocannabinoids |
US5264373A (en) * | 1987-02-17 | 1993-11-23 | Abbott Laboratories | Fluorescence polarization immunoassay for tetrahydrocannabinoids |
JPS63257177A (ja) * | 1987-04-13 | 1988-10-25 | Hitachi Ltd | 超高圧水銀灯 |
JPS63257178A (ja) * | 1987-04-13 | 1988-10-25 | Nec Home Electronics Ltd | コンパクト型蛍光ランプ |
JPH01273582A (ja) * | 1988-04-26 | 1989-11-01 | Matsushita Electric Ind Co Ltd | モノクローナル抗体産生細胞ライン及びモノクローナル抗体及び免疫原 |
JP2600850B2 (ja) * | 1988-10-04 | 1997-04-16 | 松下電器産業株式会社 | テトラヒドロカンナビノール誘導体 |
US5237057A (en) * | 1992-04-06 | 1993-08-17 | Biosite Diagnostics, Inc. | Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels |
US5315015A (en) * | 1992-11-10 | 1994-05-24 | Hoffmann-La Roche Inc. | Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same |
-
1995
- 1995-04-05 US US08/417,331 patent/US5817766A/en not_active Expired - Lifetime
-
1996
- 1996-03-26 DE DE69609108T patent/DE69609108T2/de not_active Expired - Lifetime
- 1996-03-26 AT AT96104776T patent/ATE194339T1/de active
- 1996-03-26 ES ES96104776T patent/ES2148617T3/es not_active Expired - Lifetime
- 1996-03-26 EP EP96104776A patent/EP0736529B1/en not_active Expired - Lifetime
- 1996-03-26 CA CA002172663A patent/CA2172663C/en not_active Expired - Lifetime
- 1996-04-05 JP JP08433196A patent/JP4229990B2/ja not_active Expired - Fee Related
-
2008
- 2008-08-27 JP JP2008217504A patent/JP2009051839A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2009051839A (ja) | 2009-03-12 |
ATE194339T1 (de) | 2000-07-15 |
CA2172663A1 (en) | 1996-10-06 |
JP4229990B2 (ja) | 2009-02-25 |
JPH08283258A (ja) | 1996-10-29 |
DE69609108T2 (de) | 2001-03-22 |
EP0736529A1 (en) | 1996-10-09 |
CA2172663C (en) | 2008-12-02 |
DE69609108D1 (de) | 2000-08-10 |
US5817766A (en) | 1998-10-06 |
EP0736529B1 (en) | 2000-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2148617T3 (es) | Reactivos perfeccionados para un inmunoensayo de cannabinoides. | |
PT852243E (pt) | Polioxido de etileno tendo um residuo de um sacarideo numa das extremidades e um grupo funcional diferente na outra extremidade e processo para a producao do mesmo | |
NO875476D0 (no) | Elektrokjemiluminiscente proever. | |
MX168720B (es) | Composicion para impartir al cabello propiedades de acondicionamiento mejoradas | |
PT82682B (pt) | Processo para a preparacao de derivados da quinazolina e de composicoes farmaceuticas que os contem | |
CO4560475A1 (es) | Un producto de carbon modificado | |
EA199900474A1 (ru) | Предупреждение потери и восстановление костной массы некоторыми агонистами простагландина | |
DE69528362D1 (de) | Oligomere phosphoramidat- und phosphorthioamidatverbindungen | |
ES2005059B3 (es) | Nuevo procedimiento de preparacion de fibratos. | |
ES2168953B1 (es) | Derivados de oxima y su uso como acidos latentes | |
MX9207137A (es) | Nuevos oligodesoxirribonucleotidos, que tienen una actividad anti-isquemica, y metodos para su preparacion | |
MA19996A1 (fr) | Procede de preparation de derives disubstitues de la proline | |
ES539668A0 (es) | Procedimiento para la preparacion de nuevas 5,11-dihidro-6h-dibenzo (b,e)azepin-6-onas sustituidas | |
NO911880L (no) | Derivater av biologisk aktive molekyler, samt analysesettfor bestemmelse av mediatorer. | |
ES548357A0 (es) | Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2. | |
NO20006109L (no) | Analytisk metode som benytter multippel virusmerking | |
ES2132956T3 (es) | Aerogeles organofuncionalizados. | |
AR001813A1 (es) | Derivados de cromona procedimiento para prepararlos y las composiciones farmacéutica que los contienen | |
BR9801085A (pt) | Processo para a preparação de moenomicina a. | |
BR9907497A (pt) | Compostos de imidazolina, um processo para seu preparo e compostos farmacêuticos contendo os mesmos | |
ES2101886T3 (es) | Procedimientos colorimetricos y reactivos para el ensayo de calcio en una muestra de ensayo. | |
ES2168355T3 (es) | Derivados de bisulfuro de indano-2-mercaptoacetilamida utiles como inhibidores de la encefalinasa. | |
ES2151491T3 (es) | Reactivos y procedimientos de cuantificacion de la imipramina o de la desipramina en fluidos biologicos. | |
AR004719A1 (es) | Compuestos debisindolilmaleimidas con un punte n, n' y formulaciones farmaceuticas que los contienen, dichos compuestos son utiles comointermediarios para preparar otras bisindolilmaleimidas que poseen dicho puente n, n' | |
ES2081900T3 (es) | Composiciones de ensayo de barbituratos y metodos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 736529 Country of ref document: ES |