MA19996A1 - Procede de preparation de derives disubstitues de la proline - Google Patents

Procede de preparation de derives disubstitues de la proline

Info

Publication number
MA19996A1
MA19996A1 MA20217A MA20217A MA19996A1 MA 19996 A1 MA19996 A1 MA 19996A1 MA 20217 A MA20217 A MA 20217A MA 20217 A MA20217 A MA 20217A MA 19996 A1 MA19996 A1 MA 19996A1
Authority
MA
Morocco
Prior art keywords
preparation
proline derivatives
disubstituted
disubstituted proline
aryl
Prior art date
Application number
MA20217A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of MA19996A1 publication Critical patent/MA19996A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/10—Mercury compounds
MA20217A 1983-01-07 1984-01-06 Procede de preparation de derives disubstitues de la proline MA19996A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833300316 DE3300316A1 (de) 1983-01-07 1983-01-07 Disubstituierte prolinderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
MA19996A1 true MA19996A1 (fr) 1984-10-01

Family

ID=6187824

Family Applications (1)

Application Number Title Priority Date Filing Date
MA20217A MA19996A1 (fr) 1983-01-07 1984-01-06 Procede de preparation de derives disubstitues de la proline

Country Status (21)

Country Link
US (1) US4684662A (fr)
EP (1) EP0115639B1 (fr)
JP (3) JPS59144755A (fr)
KR (1) KR900007216B1 (fr)
AT (1) ATE25677T1 (fr)
AU (1) AU575306B2 (fr)
CA (1) CA1220213A (fr)
DE (2) DE3300316A1 (fr)
DK (2) DK171641B1 (fr)
ES (2) ES8407471A1 (fr)
FI (1) FI81780C (fr)
GR (1) GR79462B (fr)
HU (1) HU190541B (fr)
IE (1) IE56520B1 (fr)
IL (1) IL70618A (fr)
MA (1) MA19996A1 (fr)
NO (1) NO165921C (fr)
NZ (1) NZ206733A (fr)
PH (1) PH19979A (fr)
PT (1) PT77924B (fr)
ZA (1) ZA84113B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
NZ202903A (en) * 1981-12-29 1988-01-08 Hoechst Ag 1-- pe pyrrol-2-yl-carboxylic acid derivatives and pharmaceutical compositions
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
US5118811A (en) * 1989-04-13 1992-06-02 Japan Tobacco Inc. Amino acid derivatives possessing prolyl endopeptidase-inhibitory activities
TW492957B (en) * 1996-11-07 2002-07-01 Novartis Ag N-substituted 2-cyanopyrrolidnes
CA2390231A1 (fr) * 1999-11-12 2001-05-17 Paul Jackson Inhibiteurs de la dipeptidyl peptidase iv; methodes de fabrication et d'utilisation desdits inhibiteurs
US20040152745A1 (en) * 1999-11-12 2004-08-05 Guilford Pharmaceuticals, Inc. Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
EP1615885A1 (fr) * 2003-04-15 2006-01-18 Warner-Lambert Company LLC Derives bicycliques b]-fusionnes de proline et leur utilisation pour traiter des etats arthritiques
CA2521364A1 (fr) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc Derives de proline bicycliques [c]-condenses et leur utilisation pour traiter des pathologies arthritiques
CA2586760A1 (fr) * 2004-11-05 2006-05-18 Edward S. Wilson Composition de ramipril stabilisee et procedes de fabrication

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE315190C (fr) *
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
DE3151690A1 (de) * 1981-12-29 1983-07-07 Hoechst Ag, 6230 Frankfurt "neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung"

Also Published As

Publication number Publication date
DE3369980D1 (en) 1987-04-09
ES528703A0 (es) 1984-09-16
HU190541B (en) 1986-09-29
JPH0583541B2 (fr) 1993-11-26
GR79462B (fr) 1984-10-30
IL70618A (en) 1987-10-30
JPH0578312A (ja) 1993-03-30
FI81780B (fi) 1990-08-31
ZA84113B (en) 1984-08-29
IL70618A0 (en) 1984-04-30
JPH0610190B2 (ja) 1994-02-09
ATE25677T1 (de) 1987-03-15
ES8407471A1 (es) 1984-09-16
JPH056542B2 (fr) 1993-01-26
AU2314684A (en) 1984-07-12
NO840048L (no) 1984-07-09
PT77924A (de) 1984-02-01
FI840027A (fi) 1984-07-08
DK33196A (da) 1996-03-21
IE56520B1 (en) 1991-08-28
NZ206733A (en) 1988-02-29
EP0115639A1 (fr) 1984-08-15
DK171641B1 (da) 1997-03-03
FI81780C (fi) 1990-12-10
ES530311A0 (es) 1984-11-01
IE840023L (en) 1984-07-07
DK6384A (da) 1984-07-08
CA1220213A (fr) 1987-04-07
JPH0570423A (ja) 1993-03-23
FI840027A0 (fi) 1984-01-05
DK171642B1 (da) 1997-03-03
JPS59144755A (ja) 1984-08-18
ES8500900A1 (es) 1984-11-01
NO165921B (no) 1991-01-21
DK6384D0 (da) 1984-01-06
NO165921C (no) 1991-05-02
PH19979A (en) 1986-08-26
DE3300316A1 (de) 1984-07-12
KR840007583A (ko) 1984-12-08
AU575306B2 (en) 1988-07-28
EP0115639B1 (fr) 1987-03-04
PT77924B (de) 1986-05-30
US4684662A (en) 1987-08-04
KR900007216B1 (ko) 1990-10-05

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