NO165921C - Fremgangsmaate for fremstilling av disubstituerte prolinderivater. - Google Patents

Fremgangsmaate for fremstilling av disubstituerte prolinderivater.

Info

Publication number
NO165921C
NO165921C NO840048A NO840048A NO165921C NO 165921 C NO165921 C NO 165921C NO 840048 A NO840048 A NO 840048A NO 840048 A NO840048 A NO 840048A NO 165921 C NO165921 C NO 165921C
Authority
NO
Norway
Prior art keywords
preparation
procedure
proline derivatives
disubstituted
disubstituted proline
Prior art date
Application number
NO840048A
Other languages
English (en)
Other versions
NO165921B (no
NO840048L (no
Inventor
Rainer Henning
Hansjoerg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO840048L publication Critical patent/NO840048L/no
Publication of NO165921B publication Critical patent/NO165921B/no
Publication of NO165921C publication Critical patent/NO165921C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/10Mercury compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Hydrogenated Pyridines (AREA)
  • Glass Compositions (AREA)
  • Golf Clubs (AREA)
  • Pyrane Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
NO840048A 1983-01-07 1984-01-06 Fremgangsmaate for fremstilling av disubstituerte prolinderivater. NO165921C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833300316 DE3300316A1 (de) 1983-01-07 1983-01-07 Disubstituierte prolinderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (3)

Publication Number Publication Date
NO840048L NO840048L (no) 1984-07-09
NO165921B NO165921B (no) 1991-01-21
NO165921C true NO165921C (no) 1991-05-02

Family

ID=6187824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO840048A NO165921C (no) 1983-01-07 1984-01-06 Fremgangsmaate for fremstilling av disubstituerte prolinderivater.

Country Status (21)

Country Link
US (1) US4684662A (no)
EP (1) EP0115639B1 (no)
JP (3) JPS59144755A (no)
KR (1) KR900007216B1 (no)
AT (1) ATE25677T1 (no)
AU (1) AU575306B2 (no)
CA (1) CA1220213A (no)
DE (2) DE3300316A1 (no)
DK (2) DK171641B1 (no)
ES (2) ES528703A0 (no)
FI (1) FI81780C (no)
GR (1) GR79462B (no)
HU (1) HU190541B (no)
IE (1) IE56520B1 (no)
IL (1) IL70618A (no)
MA (1) MA19996A1 (no)
NO (1) NO165921C (no)
NZ (1) NZ206733A (no)
PH (1) PH19979A (no)
PT (1) PT77924B (no)
ZA (1) ZA84113B (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
GR78413B (no) * 1981-12-29 1984-09-27 Hoechst Ag
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
EP0419683A4 (en) * 1989-04-13 1992-03-11 Japan Tobacco Inc. New amino acid derivatives having prolylendopeptidase inhibitor activity
TW492957B (en) * 1996-11-07 2002-07-01 Novartis Ag N-substituted 2-cyanopyrrolidnes
US20040152745A1 (en) * 1999-11-12 2004-08-05 Guilford Pharmaceuticals, Inc. Dipeptidyl peptidase IV inhibitors and methods of making and using dipeptidyl peptidase IV inhibitors
AU1916401A (en) * 1999-11-12 2001-06-06 Guilford Pharmaceuticals Inc. Dipeptidyl peptidase iv inhibitors and methods of making and using dipeptidyl peptidase iv inhibitors
MXPA05011168A (es) * 2003-04-15 2005-12-14 Warner Lambert Co Derivados de prolina biciclicos [b]-condensados y sus usos para tratar afecciones artriticas.
BRPI0409428A (pt) * 2003-04-15 2006-04-18 Warner Lambert Co derivados de prolina bicìclicos [c]-fundidos e a sua utilização para tratar estados artrìticos
CA2586547A1 (en) * 2004-11-05 2006-05-11 King Pharmaceuticals Research & Development, Inc. Stabilized individually coated ramipril particles, compositions and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE315190C (no) *
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
DE3151690A1 (de) * 1981-12-29 1983-07-07 Hoechst Ag, 6230 Frankfurt "neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung"

Also Published As

Publication number Publication date
ES530311A0 (es) 1984-11-01
JPH056542B2 (no) 1993-01-26
DK33196A (da) 1996-03-21
PT77924A (de) 1984-02-01
FI840027A0 (fi) 1984-01-05
KR840007583A (ko) 1984-12-08
MA19996A1 (fr) 1984-10-01
ES8500900A1 (es) 1984-11-01
NO165921B (no) 1991-01-21
JPH0570423A (ja) 1993-03-23
ZA84113B (en) 1984-08-29
FI840027A (fi) 1984-07-08
HU190541B (en) 1986-09-29
DE3369980D1 (en) 1987-04-09
AU2314684A (en) 1984-07-12
FI81780B (fi) 1990-08-31
CA1220213A (en) 1987-04-07
PT77924B (de) 1986-05-30
EP0115639B1 (de) 1987-03-04
DE3300316A1 (de) 1984-07-12
DK171641B1 (da) 1997-03-03
FI81780C (fi) 1990-12-10
ATE25677T1 (de) 1987-03-15
IL70618A0 (en) 1984-04-30
AU575306B2 (en) 1988-07-28
NZ206733A (en) 1988-02-29
PH19979A (en) 1986-08-26
DK6384A (da) 1984-07-08
IE56520B1 (en) 1991-08-28
EP0115639A1 (de) 1984-08-15
ES8407471A1 (es) 1984-09-16
NO840048L (no) 1984-07-09
IE840023L (en) 1984-07-07
ES528703A0 (es) 1984-09-16
IL70618A (en) 1987-10-30
JPS59144755A (ja) 1984-08-18
JPH0583541B2 (no) 1993-11-26
KR900007216B1 (ko) 1990-10-05
GR79462B (no) 1984-10-30
JPH0610190B2 (ja) 1994-02-09
US4684662A (en) 1987-08-04
JPH0578312A (ja) 1993-03-30
DK171642B1 (da) 1997-03-03
DK6384D0 (da) 1984-01-06

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