ES2081900T3 - Composiciones de ensayo de barbituratos y metodos. - Google Patents
Composiciones de ensayo de barbituratos y metodos.Info
- Publication number
- ES2081900T3 ES2081900T3 ES90122298T ES90122298T ES2081900T3 ES 2081900 T3 ES2081900 T3 ES 2081900T3 ES 90122298 T ES90122298 T ES 90122298T ES 90122298 T ES90122298 T ES 90122298T ES 2081900 T3 ES2081900 T3 ES 2081900T3
- Authority
- ES
- Spain
- Prior art keywords
- fluorescent
- immunity
- analogs
- barbiturics
- immunogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
LA INVENCION ACTUAL PROPORCIONA LOS METODOS Y LOS COMPUESTOS PARA PROBAR MUESTRAS BIOLOGICAS, TALES COMO SUERO HUMANO, PARA BARBITURICOS. EN UN PRIMER ASPECTO, SE PROPORCIONARAN ANALOGOS DE BARBITURICOS DERIVADOS CON FLUORESCENCIA Y OTROS DERIVADOS CON POLIPETIDOS INMUNOGENICOS. LOS ANALOGOS FLUORESCENTES SE EMPLEAN COMO TRAZADORES EN PRUEBAS DE INMUNIDAD HOMEGENEAS COMPETITIVAS, ASI POR EJ: UNA PRUEBA DE INMUNIDAD A LA POLARIZACION FLUORESCENTE, PARA DETECCION DE BARBITURICOS. LOS ANALOGOS INMUNOGENICOS SE EMPLEAN PARA HACER ANTISUEROS ANTIBARBITURICOS DE LA INVENCION A UTILIZAR EN EL METODO DE PRUEBAS DE INMUNIDAD. TAMBIEN SE PROPORCIONAN INTERMEDIARIOS PARA PREPARAR LOS ANALOGOS FLUORESCENTES E INMUNOGENICOS. ADEMAS, SE PROPORCIONAN KITS DE PRUEBAS, QUE COMPRENDEN UN TRAZADOR FLUORESCENTE Y UN ANTISUERO DE ACUERDO CON LA INVENCION, PARA ANALIZAR MUESTRAS BIOLOGICAS MEDIANTE PRUEBAS DE INMUNIDAD DE POLARIZACION FLUORESCENTE PARA LA PRESENCIA DE UN BARBITURICO. TAMBIEN SE PROPORCIONA UN PERFECCIONAMIENTO DE LAS PRUEBAS DE INMUNIDAD PARA LAS ANALITICAS DE LOS SUEROS, DONDE UNOS MEDIOS DE TRANSFERENCIA, TALES COMO UNA PIPETA, SE UTILIZARAN REPETIDAMENTE PARA TRANSFERIR DISTINTAS MUESTRAS AL SISTEMA DE PRUEBAS. EN EL PERFECCIONAMIENTO SE UTILIZARA UNA SOLUCION ACUOSA DE UN COMPUESTO ESPECIFICO, QUE COMPRENDE DIMETILSULFOXIDO Y UN ALCALI HALOIDEO, PARA LIMPIAR LOS MEDIOS DE TRANSFERENCIA ENTRE DICHAS TRANSFERENCIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/441,956 US5096838A (en) | 1989-11-27 | 1989-11-27 | Barbiturate assay compositions and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2081900T3 true ES2081900T3 (es) | 1996-03-16 |
Family
ID=23754973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90122298T Expired - Lifetime ES2081900T3 (es) | 1989-11-27 | 1990-11-22 | Composiciones de ensayo de barbituratos y metodos. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5096838A (es) |
EP (1) | EP0430065B1 (es) |
JP (1) | JP3065097B2 (es) |
CA (1) | CA2030689C (es) |
DE (1) | DE69023615T2 (es) |
ES (1) | ES2081900T3 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0517327B1 (en) * | 1991-06-07 | 2001-08-16 | Johnson & Johnson Clinical Diagnostics, Inc. | Immunoassay with labeled hapten analogues |
US5326708A (en) * | 1992-02-28 | 1994-07-05 | Lewis Douglas E | Forensically acceptable determinations of gestational fetal exposure to drugs and other chemical agents |
US5840307A (en) * | 1995-03-31 | 1998-11-24 | Immulogic Pharmacuetical Corp. | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation |
ES2210356T3 (es) * | 1995-03-31 | 2004-07-01 | Xenova Research Limited | Conjugados de haptano-transportador para empleo en terapia contra el uso de drogas. |
DE60335428D1 (de) * | 2002-01-31 | 2011-02-03 | Randox Lab Ltd | Immunogene, Antikörper und Konjugate für Ketamin und dessen Metaboliten |
US8133743B2 (en) * | 2007-10-19 | 2012-03-13 | Roche Diagnostics Operations, Inc. | Phenobarbital derivatives useful in immunoassay |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923995A (en) * | 1968-08-05 | 1975-12-02 | Kendall & Co | Anticonvulsant compositions containing diphenylhydantoin compounds and method of using same |
US4107157A (en) * | 1973-07-12 | 1978-08-15 | Hoffmann-La Roche Inc. | Barbituric acid antigens and antibodies specific therefor |
US4588697A (en) * | 1979-09-07 | 1986-05-13 | Syntex (U.S.A.) Inc. | Method for performing fluorescent protein binding assay employing novel alkyl substituted fluorescent compounds and conjugates |
AU555213B2 (en) * | 1981-02-17 | 1986-09-18 | Abbott Laboratories | N-substituted-amido-fluoresein derivatives |
US4585862A (en) * | 1981-12-11 | 1986-04-29 | Abbott Laboratories | Fluorescence polarization immunoassay |
US4476229A (en) * | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Substituted carboxyfluoresceins |
US4614823A (en) * | 1982-11-08 | 1986-09-30 | Abbott Laboratories | Aminomethylfluorescein derivatives |
-
1989
- 1989-11-27 US US07/441,956 patent/US5096838A/en not_active Expired - Lifetime
-
1990
- 1990-11-22 EP EP90122298A patent/EP0430065B1/en not_active Expired - Lifetime
- 1990-11-22 ES ES90122298T patent/ES2081900T3/es not_active Expired - Lifetime
- 1990-11-22 DE DE69023615T patent/DE69023615T2/de not_active Expired - Fee Related
- 1990-11-23 CA CA002030689A patent/CA2030689C/en not_active Expired - Lifetime
- 1990-11-26 JP JP2325148A patent/JP3065097B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0430065A2 (en) | 1991-06-05 |
CA2030689C (en) | 2002-12-03 |
EP0430065A3 (en) | 1993-03-17 |
DE69023615T2 (de) | 1996-06-13 |
EP0430065B1 (en) | 1995-11-15 |
DE69023615D1 (de) | 1995-12-21 |
JPH03190877A (ja) | 1991-08-20 |
JP3065097B2 (ja) | 2000-07-12 |
CA2030689A1 (en) | 1991-05-28 |
US5096838A (en) | 1992-03-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2052610T3 (es) | Un metodo de determinacion de anfetamina y/o metanfetamina en una muestra de ensayo. | |
ES2079390T3 (es) | Reactivos, metodo y kits para un ensayo inmunologico de polarizacion de fluorescencia de anfetaminas. | |
ES541870A0 (es) | Un procedimiento para preparar un dispositivo de ensayo para determinar la presencia de leucocitos, esterasa o proteasa en una muestra. | |
ES2062994T3 (es) | Procedimiento para la determinacion de anticuerpos. | |
DK0431456T3 (da) | Anvendelse af et tungtopløseligt salt af en heteropolysyre til bestemmelse af en analyt, tilsvarende fremgangsmåde til bestemmelsen samt hertil egnet middel | |
BR9814007A (pt) | Dispositivo de ensaio cromatográfico e processo para detectar a presença de um analito em uma amostra de sangue | |
DE3575789D1 (de) | Gleichseitige mehrfache proben und in denselben zu verwendende zusammensetzungen. | |
SE7906148L (sv) | Forfarande for framstellning av en biologisk komposition for anvendning sasom referenskontroll vid diagnostiska tester | |
BR8900409A (pt) | Processo para a deteccao da presenca de um composto marcador,estojo de ensaio,solucao com anticorpos monoclonais e composto a base de oleo | |
DE3685937D1 (de) | Testverfahren mit oberflaechengebundenem fibrinogen und loesliches markiertes fibrinogen. | |
BR8507089A (pt) | Aparelho para coleta e/ou desenvolvimento de culturas biologicas protegidas | |
ES512498A0 (es) | "metodo y su correspondiente aparato para el ensayo de anticuerpos con respecto a antigenos solubles". | |
SE7704305L (sv) | Forfarande for analys av ett biologiskt vetskeprov | |
ES522432A0 (es) | Perfeccionamientos en un dispositivo de analisis para determinar la presencia de actividad esterada en una muestra de liquido. | |
ES2081900T3 (es) | Composiciones de ensayo de barbituratos y metodos. | |
ES2196073T3 (es) | Prueba inmunologica de agentes farmacologicos facilitada con detergente. | |
ES2095858T3 (es) | Sustratos de beta-galactosidasa. | |
AR245534A1 (es) | Conjunto de reactivos (kit) de aplicacion en inmunoensayos para enzimas | |
ATE132974T1 (de) | Test, indikatoren, immunogene und antikörper für benzodiazepine | |
AU4126989A (en) | Method of and kit used in testing human males for fertility | |
ES2032296T3 (es) | Metodo inmunologico para el ensayo de hemoglobina glicosilada estable. | |
DK114387D0 (da) | Fremgangsmaade til afproevning af en biologisk, nucleinsyreholdig proeve for tilstedevaerelsen af en specifik mikroorganisme | |
ATE142335T1 (de) | Vorrichtung zur durchführung mehrerer gleichzeitiger messungen electrochemilumineszenter phänomene | |
SE8704765D0 (sv) | Immunologiskt aktiva polypeptider, anvendbara for framstellning av antimalariavacciner och diagnostest for pavisande av antisporozoantikroppar | |
ES2093601T3 (es) | Inmunoensayo de polarizacion de fluorescencia para tetrahidrocannabinoides. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 430065 Country of ref document: ES |