ES2052610T3 - Un metodo de determinacion de anfetamina y/o metanfetamina en una muestra de ensayo. - Google Patents
Un metodo de determinacion de anfetamina y/o metanfetamina en una muestra de ensayo.Info
- Publication number
- ES2052610T3 ES2052610T3 ES88100958T ES88100958T ES2052610T3 ES 2052610 T3 ES2052610 T3 ES 2052610T3 ES 88100958 T ES88100958 T ES 88100958T ES 88100958 T ES88100958 T ES 88100958T ES 2052610 T3 ES2052610 T3 ES 2052610T3
- Authority
- ES
- Spain
- Prior art keywords
- methamphetamine
- amphetamine
- reagents
- determination
- test sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/901—Drugs of abuse, e.g. narcotics, amphetamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
ESTE DESCUBRIMIENTO SE REFIERE A UN METODO Y LOS REAGENTES PARA DETERMINAR ANFETAMINA Y METANFETAMINA EN UN FLUIDO BIOLOGICO COMO POR EJEMPLO LA ORINA. EN PARTICULAR, EL DESCUBRIMIENTO SE REFIERE A UN PROCEDIMIENTO DE INMUNOENSAYO DE POLARIZACION FLUORESCENTE PARA DETERMINAR LA PRESENCIA DE ANFETAMINA Y METANFETAMINA EN UN ENSAYO SIMPLE Y A UNA NUEVA CLASE DE COMPUESTOS TRAZADORES EMPLEADOS COMO REAGENTES EN DICHOS PROCEDIMIENTOS. EL PROCEDIMIENTO DESCRITO INCLUYE EL PRETRATAMIENTO DE LA MUESTRA BIOLOGICA PARA ELIMINAR LOS REACTIVOS DE CRUCE TALES COMO LA BETA HIDROXIFENETIALAMINA MEDIANTE LA PREINCUBACION DE LA MUESTRA SOLAMENTE CON UNA SOLUCION ACUOSA QUE TIENE UN PH ENTRE 4.0 Y 7.5 SIN AJUSTE DE UN PH ALCALINO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/010,355 US4868132A (en) | 1987-02-03 | 1987-02-03 | Fluorescence polarization immunoassay for amphetamine/methamphetamine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2052610T3 true ES2052610T3 (es) | 1994-07-16 |
Family
ID=21745357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88100958T Expired - Lifetime ES2052610T3 (es) | 1987-02-03 | 1988-01-22 | Un metodo de determinacion de anfetamina y/o metanfetamina en una muestra de ensayo. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4868132A (es) |
EP (1) | EP0279213B1 (es) |
JP (1) | JPH0625763B2 (es) |
CA (1) | CA1297001C (es) |
DE (1) | DE3875354T2 (es) |
ES (1) | ES2052610T3 (es) |
Families Citing this family (39)
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JPH01272967A (ja) * | 1988-04-26 | 1989-10-31 | Matsushita Electric Ind Co Ltd | 免疫的検出法 |
ATE127928T1 (de) * | 1988-10-28 | 1995-09-15 | Abbott Lab | Verfahren und reagenzien zum nachweis von amphetamin und/oder d-methamphetamin in biologischen proben. |
US5262333A (en) * | 1988-10-28 | 1993-11-16 | Abbott Laboratories | Method and reagents for detecting amphetamine and/or D-methamphetamine in biological samples |
US5135863A (en) * | 1988-12-23 | 1992-08-04 | Syntex (U.S.A.) Inc. | Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine |
US5101015A (en) * | 1989-04-10 | 1992-03-31 | Abbott Laboratories | Reagents for an amphetamine-class fluorescence polarization immunoassay |
US5248791A (en) * | 1989-04-10 | 1993-09-28 | Abbott Laboratories | Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay |
DE69127383T2 (de) * | 1990-01-19 | 1998-03-05 | Mina Ltd | Gerät und Verfahren zur Untersuchung von Blut und zur Fingerabdruck-Identifikation |
US5238652A (en) * | 1990-06-20 | 1993-08-24 | Drug Screening Systems, Inc. | Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques |
US5304479A (en) * | 1991-12-06 | 1994-04-19 | Diagnostic Reagents, Inc. | Phencyclidine compounds and assays for its determination |
US5326708A (en) * | 1992-02-28 | 1994-07-05 | Lewis Douglas E | Forensically acceptable determinations of gestational fetal exposure to drugs and other chemical agents |
US5352803A (en) * | 1992-03-30 | 1994-10-04 | Abbott Laboratories | 5(6)-methyl substituted fluorescein derivatives |
US5470997A (en) * | 1992-04-06 | 1995-11-28 | Biosite Diagnostics Incorporated | Amphetamine derivatives and protein and polypeptide amphetamine derivative conjugates and labels |
CA2096495C (en) * | 1992-06-16 | 2002-07-09 | Kathy Palmer Ordonez | Dual analyte immunoassay |
US5478729A (en) * | 1994-04-28 | 1995-12-26 | Syntex (U.S.A.) Inc. | Immunoassay for homocysteine |
US5851887A (en) * | 1994-09-07 | 1998-12-22 | Cypress Semiconductor Corporation | Deep sub-micron polysilicon gap formation |
US5741715A (en) * | 1995-05-30 | 1998-04-21 | Roche Diagnostic Systems, Inc. | Quinidine immunoassay and reagents |
US5573955A (en) * | 1995-06-05 | 1996-11-12 | Microgenics Corp. | Reducing tyramine interference in immunoassays for amphetamine and methamphetamine |
US6544797B1 (en) | 1997-04-09 | 2003-04-08 | Biosite Diagnostics, Inc. | Compositions and methods for inhibiting light-induced inactivation of biological reagents |
US6127130A (en) * | 1998-03-13 | 2000-10-03 | The United States Of America As Represented By The Secretary Of The Navy | Multiassay method for determining the concentrations of antigens and interferants |
US6365706B1 (en) | 2000-06-21 | 2002-04-02 | Mississippi Chemical Corporation | Process for production of polyasparagine and the high nitrogen content polymer formed thereby |
US6472228B2 (en) * | 2000-12-04 | 2002-10-29 | Lifepoint, Inc. | Composition and methods for synthesis of novel tracers for detecting amphetamine and methamphetamine in samples |
US6492127B2 (en) * | 2001-01-23 | 2002-12-10 | Varian, Inc. | Lateral flow testing device with on-board chemical reactant |
US6653456B2 (en) | 2001-07-31 | 2003-11-25 | Roche Diagnostics Corporation | Site-specific aminoglycoside derivatives and their use in immunodiagnostic assays |
US7026166B2 (en) * | 2002-01-22 | 2006-04-11 | Chiron Corporation | Fluorogenic dyes |
US20030170917A1 (en) * | 2002-03-01 | 2003-09-11 | Roche Diagnostics Corporation | Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes |
US7169907B2 (en) * | 2002-03-01 | 2007-01-30 | Roche Diagnostics Operations, Inc. | Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs |
US7101980B2 (en) * | 2002-03-01 | 2006-09-05 | Roche Diagnostics Operations, Inc. | Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes |
US20040014030A1 (en) * | 2002-07-18 | 2004-01-22 | Lili Arabshahi | Enzymatic assay of HIV protease inhibitors |
US6821744B2 (en) | 2002-10-29 | 2004-11-23 | Roche Diagnostics Operations, Inc. | Method, assay, and kit for quantifying HIV protease inhibitors |
US6991911B2 (en) * | 2003-12-15 | 2006-01-31 | Dade Behring Inc. | Assay for entactogens |
US20050130243A1 (en) * | 2003-12-15 | 2005-06-16 | Zheng Yi F. | Assay for entactogens |
US7022492B2 (en) * | 2003-12-15 | 2006-04-04 | Dade Behring Inc. | Ecstasy haptens and immunogens |
US7115383B2 (en) * | 2004-03-22 | 2006-10-03 | Dade Behring Inc. | Assays for amphetamine and methamphetamine |
US7037669B2 (en) * | 2004-03-22 | 2006-05-02 | Dade Behring Inc. | Assays for amphetamine and methamphetamine using stereospecific reagents |
GB2404022B (en) | 2004-06-14 | 2005-08-10 | Cozart Bioscience Ltd | Competitive assays for the detection of methamphetamine group drugs |
GB2404023B (en) | 2004-07-02 | 2005-07-06 | Cozart Bioscience Ltd | Delta-9-tetrahydrocannabinol detection method |
CN101544552B (zh) * | 2009-05-13 | 2012-05-30 | 常州瑞明药业有限公司 | 对(邻)羟基苯基丙酮的合成方法 |
CA3066915A1 (en) | 2017-06-11 | 2018-12-20 | Molecular Express, Inc. | Methods and compositions for substance use disorder vaccine formulations and uses thereof |
CN114890958B (zh) * | 2022-02-23 | 2023-10-20 | 四川警察学院 | 双光子染料化合物、其制备方法及其应用 |
Family Cites Families (37)
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US4097586A (en) * | 1970-06-11 | 1978-06-27 | Biological Developments, Inc. | Immunochemical assay method |
US3940475A (en) * | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
US3690834A (en) * | 1971-01-11 | 1972-09-12 | Syva Co | Ligand determination with spin labeled compounds by receptor displacement |
US3704282A (en) * | 1971-04-09 | 1972-11-28 | Sidney Spector | Catecholamine antigens and antibodies specific therefor |
US3817837A (en) * | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
NL171930C (nl) * | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
US4022878A (en) * | 1972-05-15 | 1977-05-10 | Biological Developments, Inc. | Methods and compounds for producing specific antibodies |
US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
US3856469A (en) * | 1973-01-02 | 1974-12-24 | Syva Corp | Interferant removal from amphetamine immunoassay |
US4255329A (en) * | 1973-10-02 | 1981-03-10 | Syva Company | Double receptor fluorescent immunoassay |
US4041076A (en) * | 1974-10-23 | 1977-08-09 | Hoffmann-La Roche Inc. | Immunoassay for pharmacologically active phenethylamines |
US4016146A (en) * | 1974-12-10 | 1977-04-05 | Biological Developments, Inc. | Phenethylamine antigenic conjugates, their preparation, antibodies, and use |
JPS51101120A (en) * | 1975-02-28 | 1976-09-07 | Dai Ichi Kogyo Seiyaku Co Ltd | Kogen oyobi kotainoseiho |
US3966344A (en) * | 1975-09-29 | 1976-06-29 | Rexnord Inc. | Adjustable vibratory roller |
JPS54155094A (en) * | 1978-05-29 | 1979-12-06 | Seikagaku Kogyo Co Ltd | Method of changing electrical charge of antibody |
US4329281A (en) * | 1978-06-05 | 1982-05-11 | Hoffmann-La Roche Inc. | Hapten compositions |
DE2953610C1 (de) * | 1979-03-19 | 1985-04-11 | International Diagnostic Technology, Inc., Santa Clara, Calif. | Verfahren zum Bestimmen eines immunologisch aktiven Stoffs |
US4481136A (en) * | 1979-09-07 | 1984-11-06 | Syva Company | Alkyl substituted fluorescent compounds and conjugates |
US4588697A (en) * | 1979-09-07 | 1986-05-13 | Syntex (U.S.A.) Inc. | Method for performing fluorescent protein binding assay employing novel alkyl substituted fluorescent compounds and conjugates |
US4351760A (en) * | 1979-09-07 | 1982-09-28 | Syva Company | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates |
JPS56125666A (en) * | 1980-03-07 | 1981-10-02 | Fujisawa Pharmaceut Co Ltd | Immuno-analytical method for amphetamines and reagent thereof |
US4420568A (en) * | 1980-07-30 | 1983-12-13 | Abbott Laboratories | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluoresceins |
US4593089A (en) * | 1980-07-30 | 1986-06-03 | Abbott Laboratories | Fluorescent polarization immunoassay utilizing substituted triazinylaminofluorescein aminoglycosides |
JPS5745454A (en) * | 1980-09-02 | 1982-03-15 | Fuji Photo Film Co Ltd | Immunochemical measuring method for various minor components |
AU555213B2 (en) * | 1981-02-17 | 1986-09-18 | Abbott Laboratories | N-substituted-amido-fluoresein derivatives |
US4492762A (en) * | 1981-12-11 | 1985-01-08 | Abbott Laboratories | Fluorescent polarization immunoassays |
US4585862A (en) * | 1981-12-11 | 1986-04-29 | Abbott Laboratories | Fluorescence polarization immunoassay |
ATE17048T1 (de) * | 1982-05-26 | 1986-01-15 | Boots Celltech Diagnostics | Immunoassay. |
US4510251A (en) * | 1982-11-08 | 1985-04-09 | Abbott Laboratories | Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers |
US4476229A (en) * | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Substituted carboxyfluoresceins |
US4476228A (en) * | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Determination of unsaturated thyroxine binding protein sites using fluorescence polarization techniques |
US4681859A (en) * | 1984-09-21 | 1987-07-21 | Ortho Diagnostic Systems Inc. | Fluorescence polarization immunoassay for heavy antigens |
DE3583015D1 (de) * | 1984-12-28 | 1991-07-04 | Technicon Instr | Phospholipidkonjugate und deren herstellung. |
EP0199042A1 (en) * | 1985-03-26 | 1986-10-29 | Abbott Laboratories | Procainamide assay, tracers, immunogens and antibodies |
EP0201751A2 (en) * | 1985-05-08 | 1986-11-20 | Abbott Laboratories | 4'-aminomethyfluorescein derivatives for use in fluorescence polarization immunoassys |
EP0218010A3 (en) * | 1985-07-10 | 1988-01-07 | Abbott Laboratories | Ligand detection method and substituted carboxyfluorescein tracers therefor |
US4751190A (en) * | 1985-07-22 | 1988-06-14 | Abbott Laboratories | Fluorescence polarization immunoassay and reagents for use therein |
-
1987
- 1987-02-03 US US07/010,355 patent/US4868132A/en not_active Expired - Fee Related
-
1988
- 1988-01-22 EP EP88100958A patent/EP0279213B1/en not_active Expired - Lifetime
- 1988-01-22 ES ES88100958T patent/ES2052610T3/es not_active Expired - Lifetime
- 1988-01-22 DE DE8888100958T patent/DE3875354T2/de not_active Expired - Fee Related
- 1988-02-01 CA CA000557791A patent/CA1297001C/en not_active Expired - Fee Related
- 1988-02-03 JP JP63024879A patent/JPH0625763B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH0625763B2 (ja) | 1994-04-06 |
JPS63195569A (ja) | 1988-08-12 |
US4868132A (en) | 1989-09-19 |
DE3875354D1 (de) | 1992-11-26 |
CA1297001C (en) | 1992-03-10 |
DE3875354T2 (de) | 1993-05-06 |
EP0279213B1 (en) | 1992-10-21 |
EP0279213A1 (en) | 1988-08-24 |
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