ES2079390T3 - Reactivos, metodo y kits para un ensayo inmunologico de polarizacion de fluorescencia de anfetaminas. - Google Patents
Reactivos, metodo y kits para un ensayo inmunologico de polarizacion de fluorescencia de anfetaminas.Info
- Publication number
- ES2079390T3 ES2079390T3 ES90106319T ES90106319T ES2079390T3 ES 2079390 T3 ES2079390 T3 ES 2079390T3 ES 90106319 T ES90106319 T ES 90106319T ES 90106319 T ES90106319 T ES 90106319T ES 2079390 T3 ES2079390 T3 ES 2079390T3
- Authority
- ES
- Spain
- Prior art keywords
- test
- reagents
- amount
- kits
- amphetamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/901—Drugs of abuse, e.g. narcotics, amphetamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE PROPORCIONA UN ENSAYO INMUNOLOGICO DE POLARIZACION FLUORESCENTE (FPIA) PARA DETECTAR LA PRESENCIA DE UNO O MAS PRODUCTOS ANALITICOS DE TIPO ANFETAMINA EN UNA MUESTRA DE PRUEBA. EL ENSAYO DE INMUNODEFICIENCIA APROVECHA LA COMPETENCIA ENTRE EL PRODUCTO ANALITICO Y UN INDICADOR MARCADO DE FORMA FLUORESCENTE PARA EL LUGAR DE UNION EN UN ANTICUERPO ESPECIFICO PARA LOS DERIVADOS DE FENETILAMINA. LA CONCENTRACION DE PRODUCTO ANALITICO DE TIPO ANFETAMINA EN LA MUESTRA DETERMINA LA CANTIDAD DE INDICADOR QUE SE UNE AL ANTICUERPO. LA CANTIDAD DE COMPLEJO INDICADOR/ANTICUERPO FORMADO PUEDE MEDIRSE CUANTITATIVAMENTE Y ES INVERSAMENTE PROPORCIONAL A LA CANTIDAD DE PRODUCTO ANALITICO EN LA MUESTRA DE ENSAYO. ESTE INVENTO SE ENCUENTRA RELACIONADO CON LOS INDICADORES, CON LOS ELEMENTOS INMUNOGENICOS UTILIZADOS PARA OBTENER ANTICUERPOS PARA SU USO COMO REACTIVOS DE ENSAYO, Y CON LOS CONJUNTOS DE ENSAYO QUE INCLUYEN ESTOS INDICADORES Y REACTIVOS DE ENSAYO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/335,627 US5101015A (en) | 1989-04-10 | 1989-04-10 | Reagents for an amphetamine-class fluorescence polarization immunoassay |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2079390T3 true ES2079390T3 (es) | 1996-01-16 |
Family
ID=23312578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90106319T Expired - Lifetime ES2079390T3 (es) | 1989-04-10 | 1990-04-03 | Reactivos, metodo y kits para un ensayo inmunologico de polarizacion de fluorescencia de anfetaminas. |
Country Status (6)
Country | Link |
---|---|
US (2) | US5101015A (es) |
EP (1) | EP0399184B1 (es) |
JP (1) | JP2894782B2 (es) |
CA (1) | CA2014318C (es) |
DE (1) | DE69022286T2 (es) |
ES (1) | ES2079390T3 (es) |
Families Citing this family (62)
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US5326708A (en) * | 1992-02-28 | 1994-07-05 | Lewis Douglas E | Forensically acceptable determinations of gestational fetal exposure to drugs and other chemical agents |
CA2096495C (en) * | 1992-06-16 | 2002-07-09 | Kathy Palmer Ordonez | Dual analyte immunoassay |
US5573955A (en) * | 1995-06-05 | 1996-11-12 | Microgenics Corp. | Reducing tyramine interference in immunoassays for amphetamine and methamphetamine |
US6110750A (en) * | 1996-06-28 | 2000-08-29 | Sugden; Edward A. | Rapid detection method of Mycobacterium bovis by fluorescence polarization |
US20030036106A1 (en) * | 1996-10-28 | 2003-02-20 | Burke Thomas J. | Kinase and phosphatase activity measurement using fluorescence polarization |
US5968746A (en) * | 1997-11-26 | 1999-10-19 | Schneider; David R. | Method and apparatus for preserving human saliva for testing |
US6306616B1 (en) | 1998-03-27 | 2001-10-23 | Microgenics Corporation | Adsorption type confirmatory assays |
EP1066523A2 (en) * | 1998-03-27 | 2001-01-10 | Microgenics Corporation | Confirmatory assays for small molecule drugs |
US7250517B2 (en) * | 1998-04-08 | 2007-07-31 | Ewald A. Terpetschnig | Luminescent compounds |
US6538129B1 (en) | 1999-04-07 | 2003-03-25 | Ewald A. Terpetschnig | Luminescent compounds |
AU3386399A (en) * | 1998-04-08 | 1999-10-25 | Ewald A. Terpetschnig | Luminescent compounds |
US20030235846A1 (en) * | 1998-04-08 | 2003-12-25 | Terpetschnig Ewald A. | Luminescent compounds |
US7411068B2 (en) * | 1998-04-08 | 2008-08-12 | Terpetschnig Ewald A | Luminescent compounds |
DK1091733T3 (da) * | 1998-07-01 | 2006-04-03 | Warner Lambert Co | (-)-Pseudoephedrin som et sympatomimetisk lægemiddel |
GB2361473C (en) * | 2000-03-08 | 2005-06-28 | Microgenics Corp | Ecstasy-class analogs and use of same in detection of ecstasy-class compounds |
US6472228B2 (en) * | 2000-12-04 | 2002-10-29 | Lifepoint, Inc. | Composition and methods for synthesis of novel tracers for detecting amphetamine and methamphetamine in samples |
US6663831B2 (en) | 2001-04-04 | 2003-12-16 | Forefront Diagnostics, Inc. | “One-device” system for testing constituents in fluids |
EP1321772B1 (en) * | 2001-12-20 | 2008-09-17 | Randox Laboratories Ltd. | Method and kit for detecting, or determining, 3,4-methylenedioxymethamphetamine |
US20030171435A1 (en) * | 2002-01-23 | 2003-09-11 | Drug Abuse Sciences, Inc. | New amphetamine derivatives, antibodies against them and pharmaceutical compositions containing them |
US7101980B2 (en) * | 2002-03-01 | 2006-09-05 | Roche Diagnostics Operations, Inc. | Derivatives, conjugates, and antibodies for detecting ecstasy-class analytes |
US20030170917A1 (en) * | 2002-03-01 | 2003-09-11 | Roche Diagnostics Corporation | Compounds, antibodies, reagent kits, methods of producing antibodies, and methods of detecting analytes |
US7169907B2 (en) * | 2002-03-01 | 2007-01-30 | Roche Diagnostics Operations, Inc. | Derivatives, immunogens, and antibodies for detecting ecstasy-class drugs |
US20040087874A1 (en) * | 2002-10-28 | 2004-05-06 | David Schneider | Saliva collection system |
US7619059B2 (en) | 2003-07-29 | 2009-11-17 | Life Technologies Corporation | Bimolecular optical probes |
JP3615752B1 (ja) | 2003-11-18 | 2005-02-02 | 淳 高橋 | 細径樹脂捩じりブラシ |
US20050130243A1 (en) * | 2003-12-15 | 2005-06-16 | Zheng Yi F. | Assay for entactogens |
US7022492B2 (en) | 2003-12-15 | 2006-04-04 | Dade Behring Inc. | Ecstasy haptens and immunogens |
US6991911B2 (en) | 2003-12-15 | 2006-01-31 | Dade Behring Inc. | Assay for entactogens |
US7115383B2 (en) * | 2004-03-22 | 2006-10-03 | Dade Behring Inc. | Assays for amphetamine and methamphetamine |
US7037669B2 (en) * | 2004-03-22 | 2006-05-02 | Dade Behring Inc. | Assays for amphetamine and methamphetamine using stereospecific reagents |
GB2404022B (en) * | 2004-06-14 | 2005-08-10 | Cozart Bioscience Ltd | Competitive assays for the detection of methamphetamine group drugs |
US20060024768A1 (en) | 2004-07-29 | 2006-02-02 | Saladax Biomedical, Inc. | Taxol immunoassay |
US20060024769A1 (en) * | 2004-07-29 | 2006-02-02 | Saladax Biomedical Inc. | Taxol immunoassay |
US20060177883A1 (en) | 2005-02-08 | 2006-08-10 | Saladax Biomedical Inc. | 5-Fluoro-uracil immunoassay |
US20060216767A1 (en) | 2005-03-22 | 2006-09-28 | Saladax Biomedical Inc. | Docetaxel immunoassay |
ES2353212T3 (es) | 2005-03-30 | 2011-02-28 | Saladax Biomedical Inc. | Inmunoensayo de doxorrubicina. |
US7189582B2 (en) | 2005-04-27 | 2007-03-13 | Dade Behring Inc. | Compositions and methods for detection of sirolimus |
US7695975B2 (en) | 2005-06-23 | 2010-04-13 | Siemens Healthcare Diagnostics Inc. | Detection of adulterated samples |
US20070281363A1 (en) * | 2006-04-13 | 2007-12-06 | Ewald Terpetschnig | Luminescent compounds |
US20080076188A1 (en) * | 2006-06-19 | 2008-03-27 | Patsenker Leonid D | Luminescent compounds |
WO2008094637A2 (en) | 2007-01-30 | 2008-08-07 | Seta Biomedicals. Llc | Luminescent compounds |
US7790401B2 (en) | 2007-08-06 | 2010-09-07 | Siemens Healthcare Diagnostics | Methods for detection of immunosuppressant drugs |
US7910378B2 (en) | 2007-12-14 | 2011-03-22 | Siemens Healthcare Diagnostics Inc. | Methods for detection of hydrophobic drugs |
US8329424B2 (en) | 2010-06-25 | 2012-12-11 | Siemens Healthcare Diagnostics | Reduction in false results in assay measurements |
US10088490B2 (en) | 2010-08-20 | 2018-10-02 | Siemens Healthcare Diagnostics Inc. | Assay for analytes using multiple receptors |
US8426143B2 (en) | 2011-05-24 | 2013-04-23 | Saladax Biomedical Inc. | Gemcitabine immunoassay |
US8771972B2 (en) * | 2011-05-24 | 2014-07-08 | Saladax Biomedical Inc. | Clozapine immunoassay |
EP2742352B1 (en) | 2011-08-12 | 2018-02-28 | Siemens Healthcare Diagnostics Inc. | Detection of sex steroids |
US8771964B2 (en) | 2012-02-02 | 2014-07-08 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detection of methadone metabolite |
EP2867330B1 (en) | 2012-06-27 | 2018-10-10 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for liquid mixing assessment |
US9244083B2 (en) | 2012-11-30 | 2016-01-26 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin D |
US9121859B2 (en) | 2012-12-04 | 2015-09-01 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of FKBP-binding immunosuppressant drugs |
US20140308751A1 (en) | 2013-04-12 | 2014-10-16 | Siemens Healthcare Diagnostics Inc. | Assays for Analyte Homologs |
GB201313938D0 (en) * | 2013-08-05 | 2013-09-18 | Randox Lab Ltd | Immunoassay for phenethylamines of the 2C and DO sub-families |
EP3060917B1 (en) | 2013-10-24 | 2019-05-15 | Siemens Healthcare Diagnostics Inc. | Assays for macromolecular analytes |
WO2015089172A1 (en) | 2013-12-13 | 2015-06-18 | Siemens Healthcare Diagnostics Inc. | Pretreatment agent in non-agglutination assays |
US20160320416A1 (en) | 2013-12-18 | 2016-11-03 | Siemens Healthcare Diagnostics Inc. | Detection of endothelial disease |
GB201409516D0 (en) | 2014-05-29 | 2014-07-16 | Randox Lab Ltd | Immunoassay for compounds of the NBOMe family |
CN106661115A (zh) | 2014-06-27 | 2017-05-10 | 西门子医疗保健诊断公司 | 对维生素d差向异构体特异性的结合配偶体 |
KR20180021934A (ko) | 2014-06-27 | 2018-03-05 | 지멘스 헬쓰케어 다이아그노스틱스 인크. | 비타민 d 검정에서 비타민 d 에피머에 특이적인 결합 파트너 |
BR112020021157A2 (pt) * | 2018-04-19 | 2021-01-19 | Ellie LLC | Método de tratamento e teste de uma amostra que compreende um analito |
CN112202628B (zh) * | 2020-09-08 | 2022-09-02 | 杭州涂鸦信息技术有限公司 | 一种WiFi模块串口协议自动化测试系统及方法 |
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US3690834A (en) * | 1971-01-11 | 1972-09-12 | Syva Co | Ligand determination with spin labeled compounds by receptor displacement |
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ATE43662T1 (de) * | 1985-04-30 | 1989-06-15 | Bayer Ag | Verwendung von basischen amiden zur erhoehung der parasitaet von papier oder papieraehnlichen materialien. |
EP0201751A2 (en) * | 1985-05-08 | 1986-11-20 | Abbott Laboratories | 4'-aminomethyfluorescein derivatives for use in fluorescence polarization immunoassys |
EP0218010A3 (en) * | 1985-07-10 | 1988-01-07 | Abbott Laboratories | Ligand detection method and substituted carboxyfluorescein tracers therefor |
US4751190A (en) * | 1985-07-22 | 1988-06-14 | Abbott Laboratories | Fluorescence polarization immunoassay and reagents for use therein |
US4939264A (en) * | 1986-07-14 | 1990-07-03 | Abbott Laboratories | Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies |
US4868132A (en) * | 1987-02-03 | 1989-09-19 | Abbott Laboratories | Fluorescence polarization immunoassay for amphetamine/methamphetamine |
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-
1989
- 1989-04-10 US US07/335,627 patent/US5101015A/en not_active Expired - Lifetime
-
1990
- 1990-04-03 EP EP90106319A patent/EP0399184B1/en not_active Expired - Lifetime
- 1990-04-03 DE DE69022286T patent/DE69022286T2/de not_active Expired - Fee Related
- 1990-04-03 ES ES90106319T patent/ES2079390T3/es not_active Expired - Lifetime
- 1990-04-09 JP JP2093823A patent/JP2894782B2/ja not_active Expired - Fee Related
- 1990-04-10 CA CA002014318A patent/CA2014318C/en not_active Expired - Fee Related
-
1993
- 1993-06-29 US US08/083,928 patent/US5354693A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2014318A1 (en) | 1990-10-10 |
US5354693A (en) | 1994-10-11 |
DE69022286D1 (de) | 1995-10-19 |
DE69022286T2 (de) | 1996-04-18 |
EP0399184A3 (en) | 1991-12-27 |
US5101015A (en) | 1992-03-31 |
JP2894782B2 (ja) | 1999-05-24 |
JPH02300663A (ja) | 1990-12-12 |
CA2014318C (en) | 2000-08-08 |
EP0399184A2 (en) | 1990-11-28 |
EP0399184B1 (en) | 1995-09-13 |
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