KR960018583A - 면역 분석법 - Google Patents

면역 분석법 Download PDF

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Publication number
KR960018583A
KR960018583A KR1019950039227A KR19950039227A KR960018583A KR 960018583 A KR960018583 A KR 960018583A KR 1019950039227 A KR1019950039227 A KR 1019950039227A KR 19950039227 A KR19950039227 A KR 19950039227A KR 960018583 A KR960018583 A KR 960018583A
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KR
South Korea
Prior art keywords
antigen
immunoassay
antibody reaction
magnesium ions
reaction
Prior art date
Application number
KR1019950039227A
Other languages
English (en)
Inventor
요시히로 우시오
후또시 간께
Original Assignee
다나까 모또아끼
와꼬쥰야꾸고오교 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 다나까 모또아끼, 와꼬쥰야꾸고오교 가부시끼가이샤 filed Critical 다나까 모또아끼
Publication of KR960018583A publication Critical patent/KR960018583A/ko

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase

Abstract

항원-항체 반응에 기인하는 혼탁도의 변화 혹은 신란광 세기의 변화를 기초로 하는, 생체에서 얻은 샘플 중의 미량성분에 대한 면역 분석법에서, 상기 항원-항체 반응이 미리 첨가된 마그네슘 이온의 존재하에서 수행되는 경우, 높은 정확도와 재현도로 신속·용이하게 분석물을 측정할 수가 있다.

Description

면역 분석법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 살아 있는 체액에서 얻은 샘플과 반응 시약을 미리 첨가된 마그네슘 이온의 존재하에서 항원-항체 반응을 시키고, 상기 항원-항체 반응에 기인하는 혼탁도의 변화 혹은 산란광 세기의 변화를 측정하는 것을 포함하는, 살아 있는 체액 중의 어떤 성분의 농도를 측정하기 위한 면역 분석법.
  2. 제1항에 있어서, 마그네슘 이온은 마그네슘염에서 유래된 이온인 것을 특징으로 하는 방법.
  3. 제1항에 있어서, 항원-항체 반응이 수행되는 반응액 중의 마그네슘 이온의 농도는 5mM 내지 300mM인 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 항원-항체 반응이 수행되는 반응액 중의 마그네슘 이온의 농도는 30mM 내지 300mM인 것을 특징으로 하는 방법.
  5. 제1항에 있어서, 항원-항체 반응이 수행되는 반응액 중의 마그네슘 이온의 농도는 50mM 내지 300mM인 것을 특징으로 하는 방법.
  6. 제1항에 있어서, 살아 있는 체액 중의 성분은 C-반응성 단백질인 것을 특징으로 하는 면역 분석법.
  7. 제1항에 있어서, 살아 있는 체액 중의 성분은 항스트렙토리신 O인 것을 특징으로 하는 면역 분석법.
  8. 측정대상 샘플 중의 성분에 대한 항체 혹은 항원과 마그네슘 이온이 포함된 면역 분석용 시약.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950039227A 1994-11-02 1995-11-01 면역 분석법 KR960018583A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP94-293718 1994-11-02
JP29371894 1994-11-02

Publications (1)

Publication Number Publication Date
KR960018583A true KR960018583A (ko) 1996-06-17

Family

ID=17798349

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950039227A KR960018583A (ko) 1994-11-02 1995-11-01 면역 분석법

Country Status (4)

Country Link
US (1) US5962340A (ko)
EP (1) EP0710838A1 (ko)
KR (1) KR960018583A (ko)
TW (1) TW296432B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020131897A1 (en) * 2000-09-19 2002-09-19 James Samsoondar Apparatus of handling fluids
CN105301255B (zh) * 2014-04-18 2016-09-07 安徽大千生物工程有限公司 一种测定人体甘胆酸含量的试剂盒制备方法
CN105067815A (zh) * 2015-09-16 2015-11-18 浙江凯成生物科技有限公司 一种测定人血清中胃蛋白酶原i/ii含量的试剂盒
JP6926907B2 (ja) * 2017-09-29 2021-08-25 コニカミノルタ株式会社 測定用抗体分散液、その製造方法、測定用抗体分散液調製用キット、および生体物質測定方法

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NL7610608A (nl) * 1976-09-24 1978-03-29 Akzo Nv Werkwijze voor het stabiliseren van peroxidase- -bevattende composities.
US4134792A (en) * 1976-12-06 1979-01-16 Miles Laboratories, Inc. Specific binding assay with an enzyme modulator as a labeling substance
US4234564A (en) * 1977-12-19 1980-11-18 Merck & Co., Inc. Hepatitis B core antigen composition
US4302536A (en) * 1978-08-15 1981-11-24 Longenecker Robert W Colorimetric immunoassay process
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DE3038286A1 (de) * 1980-10-10 1982-05-19 Behringwerke Ag, 3550 Marburg Verfahren zur bestimmung der streptokokken-desoxiribonuclease b nach der toluidinblau o-methode
DE3323949A1 (de) * 1983-07-02 1985-01-03 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und mittel zur raschen und vollstaendigen beseitigung einer truebung in einer biologischen fluessigkeit
DE3338836A1 (de) * 1983-10-26 1985-05-09 Boehringer Mannheim Gmbh Verfahren zur bestimmung der low density lipoproteine (ldl) und reagenz zu seiner durchfuehrung
JPS6125062A (ja) * 1984-07-13 1986-02-03 Nitsusui Seiyaku Kk 免疫比濁法によるａｓｏ価の測定法
JPS6188899A (ja) * 1984-10-05 1986-05-07 Unitika Ltd クレアチンキナ−ゼ定量用試薬
US4902630A (en) * 1985-07-22 1990-02-20 Abbott Laboratories Fluorescence polarization immunoassy and reagents for measurement of c-reactive protein
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Also Published As

Publication number Publication date
EP0710838A1 (en) 1996-05-08
TW296432B (ko) 1997-01-21
US5962340A (en) 1999-10-05

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