ES2140473T3 - Derivado fosfolipido y liposoma que lo contiene. - Google Patents

Derivado fosfolipido y liposoma que lo contiene.

Info

Publication number
ES2140473T3
ES2140473T3 ES94100819T ES94100819T ES2140473T3 ES 2140473 T3 ES2140473 T3 ES 2140473T3 ES 94100819 T ES94100819 T ES 94100819T ES 94100819 T ES94100819 T ES 94100819T ES 2140473 T3 ES2140473 T3 ES 2140473T3
Authority
ES
Spain
Prior art keywords
liposoma
phospholipid derivative
phospholipid
derivative
phosfatidylethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94100819T
Other languages
English (en)
Inventor
Toshiaki Tagawa
Kaoru Awane
Kazuhiro Nagaike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Corp filed Critical Mitsubishi Chemical Corp
Application granted granted Critical
Publication of ES2140473T3 publication Critical patent/ES2140473T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5537—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom the heteroring containing the structure -C(=O)-N-C(=O)- (both carbon atoms belong to the heteroring)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBE UN DERIVADO DE FOSFOLIPIDO DE FORMULA (I), DONDE A ES UN RESIDUO DE FOSFOLIPIDO CON UNA MITAD FOSFATIDILETANOLAMINA, Y B ES UN GRUPO DE ENLACE QUE TIENE UNA MITAD GLICOL POLIALQUILENA.
ES94100819T 1993-01-22 1994-01-20 Derivado fosfolipido y liposoma que lo contiene. Expired - Lifetime ES2140473T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP02765193A JP3351476B2 (ja) 1993-01-22 1993-01-22 リン脂質誘導体及びそれを含有するリポソーム

Publications (1)

Publication Number Publication Date
ES2140473T3 true ES2140473T3 (es) 2000-03-01

Family

ID=12226829

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94100819T Expired - Lifetime ES2140473T3 (es) 1993-01-22 1994-01-20 Derivado fosfolipido y liposoma que lo contiene.

Country Status (6)

Country Link
US (2) US5556948A (es)
EP (1) EP0607978B1 (es)
JP (1) JP3351476B2 (es)
CA (1) CA2113914C (es)
DE (1) DE69421631T2 (es)
ES (1) ES2140473T3 (es)

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EP0607978A1 (en) 1994-07-27
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DE69421631D1 (de) 1999-12-23
CA2113914A1 (en) 1994-07-23
CA2113914C (en) 2003-07-29
EP0607978B1 (en) 1999-11-17
US5686101A (en) 1997-11-11
DE69421631T2 (de) 2000-06-21
US5556948A (en) 1996-09-17

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