ATE328582T1 - Antikörper und polyalkylenglycol gebundenes liposom - Google Patents

Antikörper und polyalkylenglycol gebundenes liposom

Info

Publication number
ATE328582T1
ATE328582T1 AT00917390T AT00917390T ATE328582T1 AT E328582 T1 ATE328582 T1 AT E328582T1 AT 00917390 T AT00917390 T AT 00917390T AT 00917390 T AT00917390 T AT 00917390T AT E328582 T1 ATE328582 T1 AT E328582T1
Authority
AT
Austria
Prior art keywords
liposome
polyalkylene glycol
antibodies
bonded liposome
glycol bonded
Prior art date
Application number
AT00917390T
Other languages
English (en)
Inventor
Toshiaki Tagawa
Saiko Hosokawa
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of ATE328582T1 publication Critical patent/ATE328582T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A61K47/6913—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome the liposome being modified on its surface by an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
AT00917390T 1999-04-23 2000-04-20 Antikörper und polyalkylenglycol gebundenes liposom ATE328582T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11573899 1999-04-23
JP11573799 1999-04-23

Publications (1)

Publication Number Publication Date
ATE328582T1 true ATE328582T1 (de) 2006-06-15

Family

ID=26454194

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00917390T ATE328582T1 (de) 1999-04-23 2000-04-20 Antikörper und polyalkylenglycol gebundenes liposom

Country Status (11)

Country Link
US (1) US20080014255A1 (de)
EP (2) EP1174126B1 (de)
JP (1) JP4111368B2 (de)
KR (1) KR100699059B1 (de)
CN (2) CN1561968A (de)
AT (1) ATE328582T1 (de)
AU (1) AU766570B2 (de)
CA (1) CA2370043A1 (de)
DE (1) DE60028567T2 (de)
ES (1) ES2265340T3 (de)
WO (1) WO2000064413A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8352400B2 (en) 1991-12-23 2013-01-08 Hoffberg Steven M Adaptive pattern recognition based controller apparatus and method and human-factored interface therefore
US7904187B2 (en) 1999-02-01 2011-03-08 Hoffberg Steven M Internet appliance system and method
GB9915074D0 (en) * 1999-06-28 1999-08-25 Cortecs Plc Ligand-binding composition
JP5175020B2 (ja) * 2001-04-30 2013-04-03 サイティミューン サイエンシーズ， インコーポレイテッド コロイド状金属組成物および方法
WO2003009870A1 (fr) * 2001-07-25 2003-02-06 Mitsubishi Pharma Corporation Remedes traitant le cancer du sein
KR100470535B1 (ko) * 2002-06-27 2005-02-22 재단법인서울대학교산학협력재단 유피에이 항체 부착 이뮤노리포좀
US20060057147A1 (en) 2002-10-04 2006-03-16 Mitsubishi Pharma Corporation Antibody recognizing antibody
JPWO2004089419A1 (ja) * 2003-04-04 2006-07-06 国立大学法人 東京大学 抗ｍｔ−ｍｍｐモノクローナル抗体含有脂質膜構造体
PL1639011T3 (pl) * 2003-06-30 2009-05-29 Domantis Ltd Pegilowane przeciwciała jednodomenowe (dAb)
JPWO2006030602A1 (ja) * 2004-09-16 2008-05-08 田辺三菱製薬株式会社 卵巣癌の診断および／または治療薬
WO2006054589A1 (ja) 2004-11-18 2006-05-26 Terumo Kabushiki Kaisha 医薬組成物、製剤および組み合わせ製剤
US7786273B2 (en) 2005-03-14 2010-08-31 Medimmune, Llc Macromolecules comprising a thioether cross-link
US20110096174A1 (en) * 2006-02-28 2011-04-28 King Martin T Accessing resources based on capturing information from a rendered document
US9814672B2 (en) * 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi
US20100080773A1 (en) * 2008-09-26 2010-04-01 Sdg, Inc. Orally Bioavailable Lipid-Based Constructs
US8962015B2 (en) 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
US8846053B2 (en) 2008-09-26 2014-09-30 Sdg, Inc. Orally bioavailable lipid-based constructs
EP2359852A4 (de) 2008-11-17 2015-05-20 Nat Cancer Ct Neue auf krebs gerichtete therapie mit einem spezifisch an einen tumorstromafaktor bindenden substanzkomplex und antitumirverbindung
US9149432B2 (en) 2010-03-19 2015-10-06 Massachusetts Institute Of Technology Lipid vesicle compositions and methods of use
CA2793604C (en) 2010-03-19 2015-10-06 Massachusetts Institute Of Technology Lipid vesicle compositions and methods of use
WO2013177565A1 (en) 2012-05-25 2013-11-28 Amylin Pharmaceuticals, Llc Insulin-pramlintide compositions and methods for making and using them
US11077173B2 (en) 2017-03-13 2021-08-03 Sdg, Inc. Lipid-based nanoparticles and methods using same
KR20190124269A (ko) 2017-03-13 2019-11-04 에스디지,인코포레이티드 안정성이 증진된 지질 기반 나노입자
US20200109205A1 (en) 2017-03-31 2020-04-09 The Regents Of The University Of California Compositions and methods for targeting and killing alpha-v beta-3-positive cancer stem cells (cscs) and treating drug resistant cancers
TW202104874A (zh) 2019-05-29 2021-02-01 學校法人早稻田大學 檢測生體分子用的溫度響應性螢光粒子

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3220180B2 (ja) * 1991-05-23 2001-10-22 三菱化学株式会社 薬剤含有タンパク質結合リポソーム
CA2072249C (en) * 1991-06-28 2003-06-17 Saiko Hosokawa Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
US6787153B1 (en) * 1991-06-28 2004-09-07 Mitsubishi Chemical Corporation Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
JP3351476B2 (ja) * 1993-01-22 2002-11-25 三菱化学株式会社 リン脂質誘導体及びそれを含有するリポソーム

Also Published As

Publication number Publication date
EP1174126A4 (de) 2002-09-04
CA2370043A1 (en) 2000-11-02
CN1355691A (zh) 2002-06-26
DE60028567T2 (de) 2007-05-16
CN1561968A (zh) 2005-01-12
AU766570B2 (en) 2003-10-16
JP4111368B2 (ja) 2008-07-02
EP1174126B1 (de) 2006-06-07
DE60028567D1 (de) 2006-07-20
KR20020011977A (ko) 2002-02-09
KR100699059B1 (ko) 2007-03-23
ES2265340T3 (es) 2007-02-16
AU3840700A (en) 2000-11-10
EP1563832A1 (de) 2005-08-17
US20080014255A1 (en) 2008-01-17
WO2000064413A1 (fr) 2000-11-02
EP1174126A1 (de) 2002-01-23
CN1198590C (zh) 2005-04-27

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