DK615886A - Substituerede gamma-thiobutyrolactoner til anvendelse som antikonvulsiva - Google Patents
Substituerede gamma-thiobutyrolactoner til anvendelse som antikonvulsivaInfo
- Publication number
- DK615886A DK615886A DK615886A DK615886A DK615886A DK 615886 A DK615886 A DK 615886A DK 615886 A DK615886 A DK 615886A DK 615886 A DK615886 A DK 615886A DK 615886 A DK615886 A DK 615886A
- Authority
- DK
- Denmark
- Prior art keywords
- thiobutyrolactones
- anticonvulsive
- substituted gamma
- gamma
- substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polyesters Or Polycarbonates (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/811,919 US4707491A (en) | 1985-12-20 | 1985-12-20 | Anticonvulsant γ-thiobutyrolactone derivatives |
| US81191985 | 1985-12-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK615886D0 DK615886D0 (da) | 1986-12-19 |
| DK615886A true DK615886A (da) | 1987-06-21 |
| DK167761B1 DK167761B1 (da) | 1993-12-13 |
Family
ID=25207947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK615886A DK167761B1 (da) | 1985-12-20 | 1986-12-19 | Alfa,alfa-disubstituerede gamma-thiobutyrolactoner |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4707491A (da) |
| EP (1) | EP0229007B1 (da) |
| JP (2) | JPH0764727B2 (da) |
| AT (1) | ATE58636T1 (da) |
| AU (1) | AU588953B2 (da) |
| CA (1) | CA1273946C (da) |
| DE (1) | DE3675911D1 (da) |
| DK (1) | DK167761B1 (da) |
| FI (1) | FI85471C (da) |
| IE (1) | IE59831B1 (da) |
| IL (1) | IL81019A (da) |
| NO (1) | NO865181L (da) |
| ZA (1) | ZA869585B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1145362B (it) * | 1980-03-06 | 1986-11-05 | Sigma Tau Ind Farmaceuti | Classe di acil-derivati della carnitina procedimento per la loro preparazione e loro uso terapeutico |
| US4851085A (en) * | 1988-07-11 | 1989-07-25 | Gaf Corporation | Purification of butyrolactone |
| CA2130723C (en) * | 1993-09-03 | 2006-01-31 | Wilhelm Quittmann | Process for preparing y-mercaptocarboxylic acid derivatives |
| US5776959A (en) * | 1995-06-05 | 1998-07-07 | Washington University | Anticonvulsant and anxiolytic lactam and thiolactam derivatives |
| FR2800069A1 (fr) | 1999-10-22 | 2001-04-27 | Centre Nat Rech Scient | 3-amino-2,2-di-c-alkyl-1,4-butyrolactones et 1,4- thiobutyrolactones n-substituees utiles comme stimulant de l'activite de l'acide gamma-aminobutyrique et leur procede de preparation |
| US20030037354A1 (en) * | 2001-08-02 | 2003-02-20 | Ornitz David M. | Animal model with disrupted Fgf14 gene |
| CN114891221B (zh) * | 2019-10-14 | 2023-09-15 | 中国科学院上海有机化学研究所 | 聚（γ-硫代丁内酯） |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2402639A (en) * | 1940-09-19 | 1946-06-25 | Du Pont | Lactones of mercapto carboxylic acids and process of preparing them |
| US2978460A (en) * | 1955-09-20 | 1961-04-04 | Goodrich Co B F | Thiolactones and method of preparation |
| US3488732A (en) * | 1967-02-21 | 1970-01-06 | Mobil Oil Corp | Heterocyclic ring compounds and preparation of same |
-
1985
- 1985-12-20 US US06/811,919 patent/US4707491A/en not_active Expired - Lifetime
-
1986
- 1986-12-18 IL IL81019A patent/IL81019A/xx not_active IP Right Cessation
- 1986-12-19 AU AU66777/86A patent/AU588953B2/en not_active Ceased
- 1986-12-19 NO NO865181A patent/NO865181L/no unknown
- 1986-12-19 FI FI865230A patent/FI85471C/fi not_active IP Right Cessation
- 1986-12-19 CA CA525937A patent/CA1273946C/en not_active Expired
- 1986-12-19 ZA ZA869585A patent/ZA869585B/xx unknown
- 1986-12-19 EP EP86870188A patent/EP0229007B1/en not_active Expired - Lifetime
- 1986-12-19 JP JP61303583A patent/JPH0764727B2/ja not_active Expired - Lifetime
- 1986-12-19 DK DK615886A patent/DK167761B1/da not_active IP Right Cessation
- 1986-12-19 DE DE8686870188T patent/DE3675911D1/de not_active Expired - Fee Related
- 1986-12-19 AT AT86870188T patent/ATE58636T1/de not_active IP Right Cessation
- 1986-12-19 IE IE333386A patent/IE59831B1/en not_active IP Right Cessation
-
1993
- 1993-12-20 JP JP5320374A patent/JPH0759576B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06316570A (ja) | 1994-11-15 |
| ATE58636T1 (de) | 1990-12-15 |
| JPH0764727B2 (ja) | 1995-07-12 |
| EP0229007B1 (en) | 1990-11-28 |
| NO865181L (no) | 1987-06-22 |
| IE863333L (en) | 1987-06-20 |
| AU588953B2 (en) | 1989-09-28 |
| JPH0759576B2 (ja) | 1995-06-28 |
| CA1273946A (en) | 1990-09-11 |
| FI865230A0 (fi) | 1986-12-19 |
| US4707491A (en) | 1987-11-17 |
| DK615886D0 (da) | 1986-12-19 |
| FI865230A (fi) | 1987-06-21 |
| FI85471C (fi) | 1992-04-27 |
| CA1273946C (en) | 1990-09-11 |
| JPS62158272A (ja) | 1987-07-14 |
| FI85471B (fi) | 1992-01-15 |
| IL81019A0 (en) | 1987-03-31 |
| DK167761B1 (da) | 1993-12-13 |
| IE59831B1 (en) | 1994-04-06 |
| AU6677786A (en) | 1987-06-25 |
| IL81019A (en) | 1991-08-16 |
| NO865181D0 (no) | 1986-12-19 |
| ZA869585B (en) | 1988-05-25 |
| DE3675911D1 (de) | 1991-01-10 |
| EP0229007A1 (en) | 1987-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |