ES2139605T3 - Amina terciaria triazolilada o una sal de esta. - Google Patents

Amina terciaria triazolilada o una sal de esta.

Info

Publication number
ES2139605T3
ES2139605T3 ES92918529T ES92918529T ES2139605T3 ES 2139605 T3 ES2139605 T3 ES 2139605T3 ES 92918529 T ES92918529 T ES 92918529T ES 92918529 T ES92918529 T ES 92918529T ES 2139605 T3 ES2139605 T3 ES 2139605T3
Authority
ES
Spain
Prior art keywords
heterocyclic group
triazolylated
triazolyl
salt
tertiary amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92918529T
Other languages
English (en)
Inventor
Minoru Okada
Eiji Kawaminami
Toru Yoden
Masafumi Kudou
Yasuo Isomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2139605T3 publication Critical patent/ES2139605T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicinal Preparation (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UN COMPUESTO DE AMINO TERCIARIO TRIAZOLILADO REPRESENTADO POR LA FORMULA (I) O UNA SAL CONSIGUIENTE, QUE TIENE UNA ACTIVIDAD INHIBIDORA DE LA AROMATASA Y QUE ES UTIL PARA PREVENIR Y TRATAR EL CANCER DE PECHO, MASTOPATIAS, ENDOMETRIOSIS, PROSTATOMEGALIA, ETC., EN LA QUE A REPRESENTA UN ENLACE SIMPLE, ALQUILENO INFERIOR O CARBONILO; B REPRESENTA ALQUILO INFERIOR, ARILO, UN GRUPO HETEROCICLICO DE 5 UNDIDO A UN GRUPO HETEROCICLICO; D REPRESENTA ARILO, GRUPO HETEROCICLICO DE 5O 6 HETEROCICLICO; E REPRESENTA 4H
ES92918529T 1991-09-02 1992-08-27 Amina terciaria triazolilada o una sal de esta. Expired - Lifetime ES2139605T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24826891 1991-09-02
JP34401191 1991-12-02

Publications (1)

Publication Number Publication Date
ES2139605T3 true ES2139605T3 (es) 2000-02-16

Family

ID=26538684

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92918529T Expired - Lifetime ES2139605T3 (es) 1991-09-02 1992-08-27 Amina terciaria triazolilada o una sal de esta.

Country Status (20)

Country Link
US (1) US5674886A (es)
EP (1) EP0641785B1 (es)
KR (1) KR100204697B1 (es)
CN (1) CN1035817C (es)
AT (1) ATE186052T1 (es)
AU (1) AU665569B2 (es)
BG (1) BG61688B1 (es)
CA (1) CA2116773C (es)
DE (1) DE69230225T2 (es)
ES (1) ES2139605T3 (es)
FI (1) FI940988A (es)
HU (1) HU220863B1 (es)
MX (1) MX9204996A (es)
NO (1) NO305284B1 (es)
PT (1) PT100821B (es)
RO (1) RO114129B1 (es)
RU (1) RU2124010C1 (es)
TW (1) TW225526B (es)
UA (1) UA41295C2 (es)
WO (1) WO1993005027A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US7022702B2 (en) * 2000-04-07 2006-04-04 Qlt Inc. Antiproliferative 1,2,3-thiadiazole compounds
US6420400B1 (en) 2000-04-07 2002-07-16 Kinetek Pharmaceuticals, Inc. Antiproliferative 1,2,3-thiadiazole compounds
PT1355889E (pt) * 2000-12-22 2006-09-29 Ortho Mcneil Pharm Inc Derivados diamina triazole substituidos como inibidores de cinase
GB0120147D0 (en) * 2001-08-17 2001-10-10 Metris Therapeutics Ltd Treatment method
GB0127923D0 (en) * 2001-11-21 2002-01-16 Sterix Ltd Compound
MXPA04004802A (es) * 2001-11-21 2004-08-11 Sterix Ltd Derivados del 1,2,4-triazol que contienen un grupo sulfamato como inhibidores de aromatasa.
JP2004196795A (ja) * 2002-12-16 2004-07-15 Wyeth 外部寄生虫駆除剤としてのｎ−フェニル−３−シクロプロピルピラゾール−４−カルボニトリル
EP1431292A1 (en) * 2002-12-16 2004-06-23 Laboratoire Theramex 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors
EP1544195A1 (en) * 2003-12-15 2005-06-22 Laboratoire Theramex 1-N-phenyl-amino- 1H-imidazole derivatives and pharmaceutical compositions containing them
CA2549603A1 (en) * 2003-12-15 2005-06-30 Laboratoire Theramex 1-n-phenyl-amino-1h-imidazole derivatives and pharmaceutical compositions containing them
AU2011226950B9 (en) * 2003-12-15 2013-04-11 Laboratoire Theramex 1-N-phenyl-amino-1H-imidazole derivatives and pharmaceutical compositions containing them
GB0411562D0 (en) * 2004-05-24 2004-06-23 Sterix Ltd Compound
WO2011002096A1 (ja) * 2009-07-03 2011-01-06 独立行政法人理化学研究所 Ｐｅｔ用標識化合物
GB0914767D0 (en) * 2009-08-24 2009-09-30 Sterix Ltd Compound
CN113387894B (zh) * 2021-06-22 2023-02-24 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) 1-n-苯乙腈基氨基-三氮唑和嘧啶衍生物及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609666A (en) * 1984-06-18 1986-09-02 Eli Lilly And Company Aromatase inhibiting derivatives of α,α-bis(4-halophenyl)methyltetrazoles and triazoles
US4602025A (en) * 1984-06-18 1986-07-22 Eli Lilly And Company Aromatase inhibitors
US4749713A (en) 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
CH677925A5 (es) * 1986-12-03 1991-07-15 Sandoz Ag
US5041458A (en) * 1987-03-20 1991-08-20 E. I. Du Pont De Nemours And Company Fungicidal aminotriazoles and aminoimidazoles
KR890700582A (ko) * 1987-03-20 1989-04-25 사무엘 에스. 블라이트 살진균성 아미노트리아졸 및 아미노이미다졸
NZ224714A (en) 1987-06-01 1990-03-27 Janssen Pharmaceutica Nv Substituted benzotriazole derivatives and pharmaceutical compositions
US4806554A (en) * 1988-01-11 1989-02-21 Hoechst-Roussel Pharmaceuticals, Inc. Pyrazol and indazolpyridinamines
GR900100380A (el) * 1989-05-20 1991-10-10 Fisons Plc Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης.

Also Published As

Publication number Publication date
US5674886A (en) 1997-10-07
NO940686D0 (no) 1994-02-28
CN1035817C (zh) 1997-09-10
RO114129B1 (ro) 1999-01-29
AU2487492A (en) 1993-04-05
HUT67249A (en) 1995-03-28
HU220863B1 (en) 2002-06-29
BG98618A (bg) 1995-03-31
FI940988A0 (fi) 1994-03-02
NO305284B1 (no) 1999-05-03
EP0641785A4 (en) 1994-06-16
CN1069974A (zh) 1993-03-17
MX9204996A (es) 1993-08-01
FI940988A (fi) 1994-04-05
DE69230225T2 (de) 2000-05-31
CA2116773C (en) 2002-12-10
WO1993005027A1 (en) 1993-03-18
CA2116773A1 (en) 1993-03-18
UA41295C2 (uk) 2001-09-17
RU2124010C1 (ru) 1998-12-27
PT100821B (pt) 1999-07-30
HU9400611D0 (en) 1994-09-28
NO940686L (es) 1994-04-29
TW225526B (es) 1994-06-21
PT100821A (pt) 1993-11-30
ATE186052T1 (de) 1999-11-15
KR100204697B1 (ko) 1999-06-15
AU665569B2 (en) 1996-01-11
DE69230225D1 (de) 1999-12-02
BG61688B1 (bg) 1998-03-31
EP0641785B1 (en) 1999-10-27
EP0641785A1 (en) 1995-03-08

Similar Documents

Publication Publication Date Title
ES2139605T3 (es) Amina terciaria triazolilada o una sal de esta.
ATE214055T1 (de) Retinoid-potenzierende verbindungen
ES2111652T3 (es) Nuevo derivado de benzotiofeno.
DK260588D0 (da) Heterocykliske ketoner
MX9202947A (es) Compuesto antibacteriano de quinolina.
HU9700069D0 (en) Heterocyclic tachykinine-receptor antagonists
YU194491A (sh) Nove hidantoinske spojine
RU94016190A (ru) Триазолилзамещенные третичные аминные соединения и их соли, способ их получения и содержащие их ингибитор ароматазы и фармацевтический состав
MY111559A (en) Triazole and imidazole compounds and their use as antifungaltherapeutic agents
DK0640595T3 (da) Substituerede tertiære aminoforbindelser og salte heraf
GR81836B (es)
ES2003100A6 (es) Un procedimiento para preparar imidazoles
AU1446892A (en) Novel oxa- or azasteroid derivative
ES2021476B3 (es) Azolilmetilciclopropano y su aplicacion como medio protector de plantas
DE69208384D1 (de) Fungizide Furanonderivate
IT1085353B (it) Composizione fungicida
IT1143792B (it) Composizione fungicida
TH13545A (th) ไนโตรเอธิลีนและไนโตรกัวนิดีนที่เป็นสารฆ่าสัตว์ขาปล้อง
TH18465A (th) สารประกอบอาโซล การผลิต และการใช้สารเหล่านี้

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 641785

Country of ref document: ES