ES2130258T3 - Compuesto amino terciario sustituido o sal de este compuesto. - Google Patents
Compuesto amino terciario sustituido o sal de este compuesto.Info
- Publication number
- ES2130258T3 ES2130258T3 ES93909428T ES93909428T ES2130258T3 ES 2130258 T3 ES2130258 T3 ES 2130258T3 ES 93909428 T ES93909428 T ES 93909428T ES 93909428 T ES93909428 T ES 93909428T ES 2130258 T3 ES2130258 T3 ES 2130258T3
- Authority
- ES
- Spain
- Prior art keywords
- compound
- tertiary amino
- substituted tertiary
- salt
- amino compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
UN COMPUESTO AMINO TERCIARIO SUSTITUIDO REPRESENTADO POR LA FORMULA GENERAL (() O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. TIENEN UNA ACTIVIDAD INHIBIDORA DE LA AROMATASA Y SON UTILES COMO AGENTES PROFILACTICOS Y/O TERAPEUTICOS PARA EL CANCER DE MAMA, LA MASTOPATIA, ENDOMETRIOSIS, HIPERTROFIA PROSTATICA, ETCETERA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13776292 | 1992-04-28 | ||
JP23429892 | 1992-08-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2130258T3 true ES2130258T3 (es) | 1999-07-01 |
Family
ID=26470979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93909428T Expired - Lifetime ES2130258T3 (es) | 1992-04-28 | 1993-04-27 | Compuesto amino terciario sustituido o sal de este compuesto. |
Country Status (14)
Country | Link |
---|---|
US (1) | US5538976A (es) |
EP (1) | EP0640595B1 (es) |
JP (1) | JP2682741B2 (es) |
KR (1) | KR0163624B1 (es) |
CN (1) | CN1039228C (es) |
AT (1) | ATE178056T1 (es) |
AU (1) | AU4023093A (es) |
CA (1) | CA2118138A1 (es) |
DE (1) | DE69324141T2 (es) |
DK (1) | DK0640595T3 (es) |
ES (1) | ES2130258T3 (es) |
GR (1) | GR3030472T3 (es) |
TW (1) | TW345577B (es) |
WO (1) | WO1993022290A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9802251D0 (en) * | 1998-02-03 | 1998-04-01 | Ciba Geigy Ag | Organic compounds |
US6756367B2 (en) | 1998-02-03 | 2004-06-29 | Novartis Ag | Benzo-oxadiazoles, -thiadiazoles and -1,4-diazines, pharmaceutical compositions containing them and a process for preparing them |
CA2327543A1 (en) * | 1998-05-06 | 1999-11-11 | Duke University | Method of treating bladder and lower urinary tract syndromes |
CA2405832A1 (en) * | 2000-04-28 | 2001-11-08 | F. Hoffmann-La Roche Ag | P-(sulfonyl)aryl and heteroaryls |
GB0120147D0 (en) * | 2001-08-17 | 2001-10-10 | Metris Therapeutics Ltd | Treatment method |
GB0127923D0 (en) | 2001-11-21 | 2002-01-16 | Sterix Ltd | Compound |
US6737433B1 (en) | 2002-12-16 | 2004-05-18 | Laboratoire Theramex | 1-N-phenylamino-1H-imidazole derivatives as aromatase inhibitors and pharmaceutical compositions containing them |
CA2640608A1 (en) * | 2006-02-01 | 2007-08-09 | Merck & Co., Inc. | Potassium channel inhibitors |
DE202009014107U1 (de) | 2009-10-16 | 2010-02-25 | HOKWANG INDUSTRIES CO., LTD., Rueifang | Druckmechanismus eines Seifenspenders mit der Möglichkeit zur Einstellung der Dosiermenge der flüssigen Seife |
JP6091431B2 (ja) * | 2011-01-31 | 2017-03-15 | ルコラス−エム.ディー.リミテッド | 医薬的使用 |
CN103183669B (zh) * | 2011-12-27 | 2015-11-18 | 湖南化工研究院 | 噻唑甲胺基吡啶类化合物及其制备方法 |
ES2970108T3 (es) | 2013-03-15 | 2024-05-27 | Abbott Lab | Analizadores de diagnóstico con carruseles de pretratamiento y métodos relacionados |
WO2014144640A1 (en) | 2013-03-15 | 2014-09-18 | Abbott Laboratories | Automated diagnostic analyzers having vertically arranged carousels and related methods |
US9335338B2 (en) | 2013-03-15 | 2016-05-10 | Toshiba Medical Systems Corporation | Automated diagnostic analyzers having rear accessible track systems and related methods |
CN104387377B (zh) * | 2014-10-14 | 2017-03-29 | 湖南海利常德农药化工有限公司 | 一种噻唑甲胺基吡啶类化合物的制备方法 |
CN105777741B (zh) * | 2014-12-18 | 2019-02-01 | 湖南化工研究院有限公司 | 噻唑烷基吡啶胺类化合物及其制备方法与应用 |
CN104770374B (zh) * | 2015-04-02 | 2017-10-17 | 湖南化工研究院有限公司 | 一种杀菌组合物 |
CN113387894B (zh) * | 2021-06-22 | 2023-02-24 | 首都医科大学脑重大疾病研究中心(北京脑重大疾病研究院) | 1-n-苯乙腈基氨基-三氮唑和嘧啶衍生物及其制备方法和应用 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4762836A (en) * | 1983-02-02 | 1988-08-09 | Eli Lilly And Company | Aromatase inhibitors |
US4774251A (en) * | 1984-06-18 | 1988-09-27 | Eli Lilly And Company | Method of inhibiting aromatase |
US4727060A (en) * | 1984-11-13 | 1988-02-23 | Ciba-Geigy Corporation | Novel 5-amino-4-hydroxyvaleryl derivatives |
DD239210A5 (de) * | 1984-11-13 | 1986-09-17 | Ciba-Geigy Ag,Ch | Verfahren zur herstellung neuer 5-amino-4-hydroxyvaleryl-derivate |
AU4717889A (en) * | 1988-12-29 | 1990-07-05 | Ciba-Geigy Ag | Amino-substituted hydroxamic acids |
DE3905364A1 (de) * | 1989-02-22 | 1990-08-23 | Hoechst Ag | Substituierte pyrimidin-derivate, verfahren zu ihrer herstellung und ihre verwendung als tool |
-
1993
- 1993-04-27 ES ES93909428T patent/ES2130258T3/es not_active Expired - Lifetime
- 1993-04-27 DE DE69324141T patent/DE69324141T2/de not_active Expired - Fee Related
- 1993-04-27 DK DK93909428T patent/DK0640595T3/da active
- 1993-04-27 WO PCT/JP1993/000548 patent/WO1993022290A1/ja active IP Right Grant
- 1993-04-27 US US08/325,383 patent/US5538976A/en not_active Expired - Fee Related
- 1993-04-27 AT AT93909428T patent/ATE178056T1/de not_active IP Right Cessation
- 1993-04-27 CA CA002118138A patent/CA2118138A1/en not_active Abandoned
- 1993-04-27 TW TW082103252A patent/TW345577B/zh active
- 1993-04-27 AU AU40230/93A patent/AU4023093A/en not_active Abandoned
- 1993-04-27 JP JP5519125A patent/JP2682741B2/ja not_active Expired - Fee Related
- 1993-04-27 EP EP93909428A patent/EP0640595B1/en not_active Expired - Lifetime
- 1993-04-27 KR KR1019940703846A patent/KR0163624B1/ko not_active IP Right Cessation
- 1993-04-28 CN CN93105330A patent/CN1039228C/zh not_active Expired - Fee Related
-
1999
- 1999-06-09 GR GR990401545T patent/GR3030472T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1993022290A1 (en) | 1993-11-11 |
AU4023093A (en) | 1993-11-29 |
CA2118138A1 (en) | 1993-10-29 |
GR3030472T3 (en) | 1999-10-29 |
KR950701321A (ko) | 1995-03-23 |
DK0640595T3 (da) | 1999-10-11 |
CN1039228C (zh) | 1998-07-22 |
DE69324141T2 (de) | 1999-08-26 |
CN1079962A (zh) | 1993-12-29 |
US5538976A (en) | 1996-07-23 |
EP0640595A4 (en) | 1995-04-12 |
DE69324141D1 (de) | 1999-04-29 |
KR0163624B1 (ko) | 1998-12-01 |
ATE178056T1 (de) | 1999-04-15 |
EP0640595A1 (en) | 1995-03-01 |
EP0640595B1 (en) | 1999-03-24 |
JP2682741B2 (ja) | 1997-11-26 |
TW345577B (en) | 1998-11-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2130258T3 (es) | Compuesto amino terciario sustituido o sal de este compuesto. | |
TR200200409T2 (tr) | Mantar öldürücü heterosiklik aromatik amitler ve bileşimleri, bunları kullanma ve hazırlama yöntemleri. | |
DE69434136D1 (de) | Dolastatin-derivate | |
ATE407155T1 (de) | Pyridin-imin polymerisationskatalysator | |
MXPA04004674A (es) | Ligados de los receptors de los canabinodies. | |
IT1283588B1 (it) | Miscela sinergica di agenti stabilizzanti | |
ATE251163T1 (de) | Bicyclische piperidin- und piperazin-verbindungen mit 5-ht6-rezeptor-affinität | |
CY1107001T1 (el) | Αζωτουχα ετεροκυκλικα παραγωγα καρβοξαμιδιου ή αλας αυτων ως αντιϊκοι παραγοντες | |
NO20014925L (no) | Farmasöytiske forbindelser | |
EA200300982A1 (ru) | Гетероциклические производные для лечения рака и других пролиферативных заболеваний | |
DE69406323D1 (de) | Substituierte Aminsäure Derivate verwendbar für die Behandlung von Arteriosclerosis | |
NO20025035D0 (no) | Oksadiazolderivater som har anticancer-effekter | |
NO982873D0 (no) | 1-metylkarbapenemderivater | |
MXPA04004802A (es) | Derivados del 1,2,4-triazol que contienen un grupo sulfamato como inhibidores de aromatasa. | |
DK0683170T3 (da) | Glucopyranosidbenzothiophener | |
EP1344777A4 (en) | IMIDAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR APPLICATION | |
SE9704770D0 (sv) | New use | |
MX9709016A (es) | 2-amino-benzoxazinonas, composiciones que las contienen y uso de las mismas. | |
GR3036968T3 (en) | Adamantyl substituted oxindoles as pharmaceutical agents | |
DE69915688D1 (de) | Benzonaphtyridin-1,8 derivate |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 640595 Country of ref document: ES |