ES2129679T3 - Derivados que contienen el grupo amidino, utiles como inhibidores de la sintasa de oxido nitrico. - Google Patents
Derivados que contienen el grupo amidino, utiles como inhibidores de la sintasa de oxido nitrico.Info
- Publication number
- ES2129679T3 ES2129679T3 ES94931893T ES94931893T ES2129679T3 ES 2129679 T3 ES2129679 T3 ES 2129679T3 ES 94931893 T ES94931893 T ES 94931893T ES 94931893 T ES94931893 T ES 94931893T ES 2129679 T3 ES2129679 T3 ES 2129679T3
- Authority
- ES
- Spain
- Prior art keywords
- nitric oxide
- inhibitors
- useful
- amidino group
- derivatives containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C07—ORGANIC CHEMISTRY
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/425—Thiazoles
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- A61K31/5545—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having eight-membered rings not containing additional condensed or non-condensed nitrogen-containing 3-7 membered rings
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- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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Abstract
LA INVENCION ACTUAL DESCRIBE COMPOSICIONES FARMACEUTICAS UTILES QUE CONTIENEN DERIVADOS DE AMIDINO DE FORMULA (I) COMO INHIBIDORES DE SINTASA DE OXIDO NITRICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14116893A | 1993-10-21 | 1993-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2129679T3 true ES2129679T3 (es) | 1999-06-16 |
Family
ID=22494486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94931893T Expired - Lifetime ES2129679T3 (es) | 1993-10-21 | 1994-10-20 | Derivados que contienen el grupo amidino, utiles como inhibidores de la sintasa de oxido nitrico. |
Country Status (15)
Country | Link |
---|---|
US (4) | US5854234A (es) |
EP (2) | EP0724570B1 (es) |
JP (1) | JPH09504028A (es) |
KR (1) | KR100342275B1 (es) |
CN (1) | CN1077886C (es) |
AT (1) | ATE177078T1 (es) |
AU (1) | AU688811B2 (es) |
CA (1) | CA2173468A1 (es) |
DE (1) | DE69416848T2 (es) |
DK (1) | DK0724570T3 (es) |
ES (1) | ES2129679T3 (es) |
GR (1) | GR3030167T3 (es) |
NO (1) | NO309303B1 (es) |
RU (1) | RU2136661C1 (es) |
WO (1) | WO1995011231A1 (es) |
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DE4418096A1 (de) * | 1994-05-24 | 1995-11-30 | Cassella Ag | Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase |
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-
1994
- 1994-10-20 AT AT94931893T patent/ATE177078T1/de not_active IP Right Cessation
- 1994-10-20 KR KR1019960702062A patent/KR100342275B1/ko not_active IP Right Cessation
- 1994-10-20 DK DK94931893T patent/DK0724570T3/da active
- 1994-10-20 US US08/448,473 patent/US5854234A/en not_active Expired - Fee Related
- 1994-10-20 EP EP94931893A patent/EP0724570B1/en not_active Expired - Lifetime
- 1994-10-20 RU RU96109321A patent/RU2136661C1/ru not_active IP Right Cessation
- 1994-10-20 ES ES94931893T patent/ES2129679T3/es not_active Expired - Lifetime
- 1994-10-20 CA CA002173468A patent/CA2173468A1/en not_active Abandoned
- 1994-10-20 DE DE69416848T patent/DE69416848T2/de not_active Expired - Fee Related
- 1994-10-20 JP JP7512153A patent/JPH09504028A/ja active Pending
- 1994-10-20 WO PCT/US1994/011832 patent/WO1995011231A1/en active IP Right Grant
- 1994-10-20 CN CN94194397A patent/CN1077886C/zh not_active Expired - Fee Related
- 1994-10-20 EP EP98114519A patent/EP0897912A1/en not_active Withdrawn
- 1994-10-20 AU AU80811/94A patent/AU688811B2/en not_active Ceased
-
1996
- 1996-04-09 NO NO961403A patent/NO309303B1/no not_active IP Right Cessation
-
1998
- 1998-05-06 US US09/073,929 patent/US6046211A/en not_active Expired - Fee Related
- 1998-07-28 US US09/123,822 patent/US6071906A/en not_active Expired - Fee Related
- 1998-07-28 US US09/123,720 patent/US6448286B1/en not_active Expired - Fee Related
-
1999
- 1999-05-07 GR GR990401248T patent/GR3030167T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH09504028A (ja) | 1997-04-22 |
DE69416848D1 (en) | 1999-04-08 |
US5854234A (en) | 1998-12-29 |
KR960705777A (ko) | 1996-11-08 |
NO961403L (no) | 1996-04-09 |
AU688811B2 (en) | 1998-03-19 |
CN1137268A (zh) | 1996-12-04 |
US6046211A (en) | 2000-04-04 |
CA2173468A1 (en) | 1995-04-27 |
KR100342275B1 (ko) | 2002-12-05 |
ATE177078T1 (de) | 1999-03-15 |
US6448286B1 (en) | 2002-09-10 |
WO1995011231A1 (en) | 1995-04-27 |
EP0897912A1 (en) | 1999-02-24 |
CN1077886C (zh) | 2002-01-16 |
NO309303B1 (no) | 2001-01-15 |
EP0724570B1 (en) | 1999-03-03 |
DE69416848T2 (de) | 1999-07-08 |
RU2136661C1 (ru) | 1999-09-10 |
US6071906A (en) | 2000-06-06 |
DK0724570T3 (da) | 1999-09-27 |
GR3030167T3 (en) | 1999-08-31 |
NO961403D0 (no) | 1996-04-09 |
AU8081194A (en) | 1995-05-08 |
EP0724570A1 (en) | 1996-08-07 |
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