MX355183B - Formulaciones de acido 3- (6- (1- (2.2- difluorobenzo [d] [1,3] dioxol-5-il) ciclopropancarboxamido) -3- metilpiridin-2-il) benzoico. - Google Patents

Formulaciones de acido 3- (6- (1- (2.2- difluorobenzo [d] [1,3] dioxol-5-il) ciclopropancarboxamido) -3- metilpiridin-2-il) benzoico.

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Publication number
MX355183B
MX355183B MX2014009117A MX2014009117A MX355183B MX 355183 B MX355183 B MX 355183B MX 2014009117 A MX2014009117 A MX 2014009117A MX 2014009117 A MX2014009117 A MX 2014009117A MX 355183 B MX355183 B MX 355183B
Authority
MX
Mexico
Prior art keywords
cyclopropanecarboxamido
difluorobenzo
dioxol
methylpyridin
benzoic acid
Prior art date
Application number
MX2014009117A
Other languages
English (en)
Other versions
MX2014009117A (es
Inventor
Jacobus Verwijs Marinus
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX2014009117A publication Critical patent/MX2014009117A/es
Publication of MX355183B publication Critical patent/MX355183B/es

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Abstract

Una composición farmacéutica que comprende el Compuesto 1, (ácido 3- (6- (1- (2,2-difluorobenzo [d] [1,3] dioxol- 5-il] ciclopropancarboxamido) -3- metilpiridin - 2-il) benzoico), y por lo menos un excipiente seleccionado de: un rellenador, un desintegrante, un tensioactivo, un aglutinante y un lubricante, en donde la composición es adecuada para administrarla por vía oral a un paciente que la requiere para tratar una enfermedad mediada por CFTR, tal como fibrosis quística. Se proporciona, además, procesos para preparar composiciones farmacéuticas que comprenden el Compuesto 1.
MX2014009117A 2012-01-25 2013-01-25 Formulaciones de acido 3- (6- (1- (2.2- difluorobenzo [d] [1,3] dioxol-5-il) ciclopropancarboxamido) -3- metilpiridin-2-il) benzoico. MX355183B (es)

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US201261590479P 2012-01-25 2012-01-25
US201261651218P 2012-05-24 2012-05-24
US201261691898P 2012-08-22 2012-08-22
US201261708691P 2012-10-02 2012-10-02
PCT/US2013/023100 WO2013112804A1 (en) 2012-01-25 2013-01-25 Formulations of 3-(6-(1-(2.2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid

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PL2806859T3 (pl) 2019-11-29
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HK1199205A1 (en) 2015-06-26
EP2806859B1 (en) 2019-05-15
ES2742277T3 (es) 2020-02-13
NZ727015A (en) 2017-12-22
KR20140117612A (ko) 2014-10-07
US20160324788A1 (en) 2016-11-10
PT2806859T (pt) 2019-09-04
DK2806859T3 (da) 2019-08-05
SG10201606135TA (en) 2016-09-29
IL233830A0 (en) 2014-09-30
SMT201900451T1 (it) 2019-11-13
CN108066306B (zh) 2021-09-07
WO2013112804A1 (en) 2013-08-01
ZA201405590B (en) 2016-08-31
CA2862859C (en) 2022-08-02
CL2014001979A1 (es) 2015-04-10
AU2013212003A1 (en) 2014-08-21
ME03464B (me) 2020-01-20
HRP20191439T1 (hr) 2019-11-15
HK1255336A1 (zh) 2019-08-16
US20130186801A1 (en) 2013-07-25
RS59262B1 (sr) 2019-10-31
CA2862859A1 (en) 2013-08-01
CY1122197T1 (el) 2020-11-25
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US20180008546A1 (en) 2018-01-11
AU2013212003C1 (en) 2018-02-08
UA114619C2 (uk) 2017-07-10
BR112014018378A2 (pt) 2021-06-08
LT2806859T (lt) 2019-10-25
US20220354797A1 (en) 2022-11-10
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