ES2122083T3 - Amplificacion simultanea de multiples dianas. - Google Patents

Amplificacion simultanea de multiples dianas.

Info

Publication number
ES2122083T3
ES2122083T3 ES94108118T ES94108118T ES2122083T3 ES 2122083 T3 ES2122083 T3 ES 2122083T3 ES 94108118 T ES94108118 T ES 94108118T ES 94108118 T ES94108118 T ES 94108118T ES 2122083 T3 ES2122083 T3 ES 2122083T3
Authority
ES
Spain
Prior art keywords
sequences
sequence
amplification
added
targeted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94108118T
Other languages
English (en)
Inventor
George Terrance Walker
James G Nadeau
Michael C Little
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2122083T3 publication Critical patent/ES2122083T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B19/00Driving, starting, stopping record carriers not specifically of filamentary or web form, or of supports therefor; Control thereof; Control of operating function ; Driving both disc and head
    • G11B19/02Control of operating function, e.g. switching from recording to reproducing
    • G11B19/04Arrangements for preventing, inhibiting, or warning against double recording on the same blank or against other recording or reproducing malfunctions
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/02Recording, reproducing, or erasing methods; Read, write or erase circuits therefor
    • G11B5/09Digital recording
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/127Structure or manufacture of heads, e.g. inductive
    • G11B5/187Structure or manufacture of the surface of the head in physical contact with, or immediately adjacent to the recording medium; Pole pieces; Gap features
    • G11B5/1875"Composite" pole pieces, i.e. poles composed in some parts of magnetic particles and in some other parts of magnetic metal layers
    • G11B5/1877"Composite" pole pieces, i.e. poles composed in some parts of magnetic particles and in some other parts of magnetic metal layers including at least one magnetic thin film
    • G11B5/1878"Composite" pole pieces, i.e. poles composed in some parts of magnetic particles and in some other parts of magnetic metal layers including at least one magnetic thin film disposed immediately adjacent to the transducing gap, e.g. "Metal-In-Gap" structure
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/127Structure or manufacture of heads, e.g. inductive
    • G11B5/31Structure or manufacture of heads, e.g. inductive using thin films
    • G11B5/3109Details
    • G11B5/3113Details for improving the magnetic domain structure or avoiding the formation or displacement of undesirable magnetic domains
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/455Arrangements for functional testing of heads; Measuring arrangements for heads
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B5/465Arrangements for demagnetisation of heads
    • GPHYSICS
    • G11INFORMATION STORAGE
    • G11BINFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B5/00Recording by magnetisation or demagnetisation of a record carrier; Reproducing by magnetic means; Record carriers therefor
    • G11B2005/0002Special dispositions or recording techniques
    • G11B2005/0005Arrangements, methods or circuits
    • G11B2005/0008Magnetic conditionning of heads, e.g. biasing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE PRESENTAN METODOS PARA LA AMPLIFICACION MULTIPLE DE SECUENCIAS DE ACIDO NUCLEICO OBJETIVADAS UTILIZANDO UN PAR SIMPLE DE MATERIALES DE ORIGEN. LAS SECUENCIAS DEFINIDAS SE AÑADEN A LOS EXTREMOS DE LAS SECUENCIAS MULTIPLES, OBJETIVADAS COMO PARTE DE LA REACCION DE AMPLIFICACION DE MANERA QUE NO SE REQUIERAN PASOS ADICIONALES PARA LA AMPLIFICACION. LAS SECUENCIAS OBJETIVADAS CON LAS SECUENCIAS AÑADIDAS, DEFINIDAS NO NECESITAN AISLARSE ANTES DE LA AMPLIFICACION. EN OTRA CONFORMACION PARA LA CO-AMPLIFICACION DE DOS SECUENCIAS OBJETIVADAS, UNA SECUENCIA QUE SE CORRESPONDA A UN SEGMENTO TERMINAL DE LA PRIMERA SECUENCIA SE AÑADE A UN EXTREMO DE LA SEGUNDA SECUENCIA Y UNA SECUENCIA QUE SE CORRESPONDA A UN SEGMENTO TERMINAL DE LA SEGUNDA SECUENCIA SE AÑADE A UN EXTREMO DE LA PRIMERA SECUENCIA. LA AMPLIFICACION DE LAS DOS SECUENCIAS REQUIERE ENTONCES SOLAMENTE UN PAR SIMPLE DE MATERIALES DE ORIGEN. ALTERNATIVAMENTE, UNA SECUENCIA SIMPLE, DEFINIDA PUEDE AÑADIRSE A LOS EXTREMOS 5'' Y 3'' DE CUALQUIER NUMERO DE OBJETIVOS SELECCIONADOS. TODAS LAS SECUENCIAS MODIFICADAS, OBJETIVADAS DE ESTA FORMA PUEDEN AMPLIFICARSE UTILIZANDO UN PAR SIMPLE DE MATERIAL DE ORIGEN QUE SE HIBRIDICEN CON LAS SECUENCIAS DEFINIDAS DE LOS EXTREMOS.
ES94108118T 1993-06-04 1994-05-26 Amplificacion simultanea de multiples dianas. Expired - Lifetime ES2122083T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/073,197 US5422252A (en) 1993-06-04 1993-06-04 Simultaneous amplification of multiple targets

Publications (1)

Publication Number Publication Date
ES2122083T3 true ES2122083T3 (es) 1998-12-16

Family

ID=22112324

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94108118T Expired - Lifetime ES2122083T3 (es) 1993-06-04 1994-05-26 Amplificacion simultanea de multiples dianas.

Country Status (10)

Country Link
US (2) US5422252A (es)
EP (1) EP0628640B1 (es)
JP (1) JP2703183B2 (es)
AU (1) AU673424B2 (es)
BR (1) BR9402174A (es)
CA (1) CA2125004C (es)
DE (1) DE69412540T2 (es)
ES (1) ES2122083T3 (es)
MX (1) MX9404063A (es)
SG (1) SG52767A1 (es)

Families Citing this family (294)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869252A (en) * 1992-03-31 1999-02-09 Abbott Laboratories Method of multiplex ligase chain reaction
US6100099A (en) * 1994-09-06 2000-08-08 Abbott Laboratories Test strip having a diagonal array of capture spots
US5470723A (en) * 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
KR100189229B1 (ko) * 1993-07-23 1999-06-01 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 핵산 증폭을 강화하는 방법
FR2708288B1 (fr) * 1993-07-26 1995-09-01 Bio Merieux Procédé d'amplification d'acides nucléiques par transcription utilisant le déplacement, réactifs et nécessaire pour la mise en Óoeuvre de ce procédé.
US6593086B2 (en) 1996-05-20 2003-07-15 Mount Sinai School Of Medicine Of New York University Nucleic acid amplification methods
US20070269799A9 (en) * 1994-06-22 2007-11-22 Zhang David Y Nucleic acid amplification methods
US5942391A (en) * 1994-06-22 1999-08-24 Mount Sinai School Of Medicine Nucleic acid amplification method: ramification-extension amplification method (RAM)
US6479235B1 (en) 1994-09-30 2002-11-12 Promega Corporation Multiplex amplification of short tandem repeat loci
CA2118048C (en) * 1994-09-30 2003-04-08 James W. Schumm Multiplex amplification of short tandem repeat loci
US5843660A (en) * 1994-09-30 1998-12-01 Promega Corporation Multiplex amplification of short tandem repeat loci
US7008771B1 (en) 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
ES2093554B1 (es) * 1995-02-17 1997-07-01 Inst De Salud Carlos Iii Procedimientos de amplificacion de genoma y mezclas de oligonucleotidos iniciadores para la deteccion y la identificacion de agentes infecciosos relacionados.
EP0826066B1 (en) * 1995-05-05 2000-09-13 The Perkin-Elmer Corporation Methods and reagents for combined pcr amplification and hybridization probing assay
US5882856A (en) 1995-06-07 1999-03-16 Genzyme Corporation Universal primer sequence for multiplex DNA amplification
JP3398809B2 (ja) * 1995-07-27 2003-04-21 日本光電工業株式会社 生体電極用導電性組成物の製法
US5747255A (en) * 1995-09-29 1998-05-05 Lynx Therapeutics, Inc. Polynucleotide detection by isothermal amplification using cleavable oligonucleotides
US5731150A (en) * 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
AU1565397A (en) 1995-12-22 1997-07-17 Behringwerke Aktiengesellschaft Detection of differences in nucleic acids
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US5667994A (en) * 1996-02-28 1997-09-16 Becton, Dickinson And Company Amplification and detection of mycobacterium avium complex species
US5691143A (en) * 1996-03-15 1997-11-25 Becton, Dickinson And Company Amplification and detection of the alpha antigen gene of mycobacterium avium complex species
JP2000505312A (ja) * 1996-03-18 2000-05-09 モレキュラー バイオロジー リソーシーズ,インコーポレイテッド 標的核酸配列増幅
US5811269A (en) * 1996-04-30 1998-09-22 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
WO1997045559A1 (en) 1996-05-29 1997-12-04 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
US5866336A (en) * 1996-07-16 1999-02-02 Oncor, Inc. Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US5702926A (en) * 1996-08-22 1997-12-30 Becton, Dickinson And Company Nicking of DNA using boronated nucleotides
US6124092A (en) * 1996-10-04 2000-09-26 The Perkin-Elmer Corporation Multiplex polynucleotide capture methods and compositions
WO1998035058A2 (en) * 1997-02-07 1998-08-13 Ribozyme Pharmaceuticals, Inc. Improved process for detection and quantification of nucleic acid molecules
ES2402947T3 (es) * 1997-04-10 2013-05-10 Stichting Katholieke Universiteit University Medical Centre Nijmegen PCA3, genes PCA3 y métodos de uso
US6054300A (en) * 1997-08-21 2000-04-25 The United States Of America As Represented By The Secretary Of Agiculture Single-site amplification (SSA): method for accelerated development of nucleic acid markers
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
AU3984699A (en) * 1998-05-12 1999-11-29 Whitehead Institute For Biomedical Research Multiplex dna amplification using chimeric primers
US6531302B1 (en) 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US6238868B1 (en) 1999-04-12 2001-05-29 Nanogen/Becton Dickinson Partnership Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology
US6309833B1 (en) 1999-04-12 2001-10-30 Nanogen/Becton Dickinson Partnership Multiplex amplification and separation of nucleic acid sequences on a bioelectronic microchip using asymmetric structures
US6326173B1 (en) * 1999-04-12 2001-12-04 Nanogen/Becton Dickinson Partnership Electronically mediated nucleic acid amplification in NASBA
CA2369016A1 (en) * 1999-04-12 2000-10-19 Nanogen/Becton Dickinson Partnership Amplification and separation of nucleic acid sequences using strand displacement amplification and bioelectronic microchip technology
US6316200B1 (en) * 2000-06-08 2001-11-13 Becton, Dickinson And Company Probes and methods for detection of nucleic acids
US20020025519A1 (en) * 1999-06-17 2002-02-28 David J. Wright Methods and oligonucleotides for detecting nucleic acid sequence variations
US6964847B1 (en) 1999-07-14 2005-11-15 Packard Biosciences Company Derivative nucleic acids and uses thereof
ATE409236T1 (de) * 1999-07-14 2008-10-15 Packard Bioscience Company Derivatisierte nukleinsäuren und deren verwendung
US6232104B1 (en) * 1999-08-17 2001-05-15 Dade Behring Inc. Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
US6472156B1 (en) 1999-08-30 2002-10-29 The University Of Utah Homogeneous multiplex hybridization analysis by color and Tm
DK1222266T3 (da) 1999-09-29 2006-07-10 Diagnocure Inc PCA3-messenger-RNA i benigne og maligne prostatavæv
DK1226166T3 (da) 1999-10-18 2010-05-25 Prince Henrys Inst Med Res Immun-interaktive fragmenter af alpha C-underenheden af inhibin
AU1601801A (en) * 1999-11-16 2001-05-30 Eric M. Eastman Methods of preparing crna
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
JP4601105B2 (ja) 1999-12-24 2010-12-22 スリーエム イノベイティブ プロパティズ カンパニー 導電性接着剤及び生体電極
EP1252182B1 (en) 2000-01-25 2012-06-20 The University Of Queensland PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA
AU2001241934A1 (en) * 2000-03-03 2001-09-17 Beckman Coulter Inc. Multiplex hybridization system for identification of pathogenic mycobacterium and method of use
EP1303639A2 (en) 2000-04-14 2003-04-23 Cornell Research Foundation, Inc. Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction
EP1290225A4 (en) * 2000-05-20 2004-09-15 Univ Michigan METHOD FOR PRODUCING A DNA BANK BY POSITIONAL REPRODUCTION
US7087414B2 (en) 2000-06-06 2006-08-08 Applera Corporation Methods and devices for multiplexing amplification reactions
EP2351853A1 (en) 2000-06-06 2011-08-03 Life Technologies Corporation Method and devices for multiplexing amplification reactions
US6605451B1 (en) 2000-06-06 2003-08-12 Xtrana, Inc. Methods and devices for multiplexing amplification reactions
DE60040874D1 (de) 2000-09-01 2009-01-02 Gen Probe Inc Amplifizierung von hiv-1 sequenzen zur detektion ven einhergehen
AUPR030900A0 (en) 2000-09-22 2000-10-12 Queensland University Of Technology Growth factor complex
GB0026424D0 (en) * 2000-10-28 2000-12-13 Ncimb Ltd Genetic analysis of microorganisms
AUPR446701A0 (en) 2001-04-18 2001-05-17 Gene Stream Pty Ltd Transgenic mammals for pharmacological and toxicological studies
WO2002090561A1 (en) * 2001-05-07 2002-11-14 Curagen Corporation Methods and composition for nucleic acid amplification
US8137911B2 (en) * 2001-05-22 2012-03-20 Cellscript, Inc. Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
WO2003080645A2 (en) 2001-07-01 2003-10-02 Keck Graduate Institute Amplification of nucleic acid fragments using nicking agents
CA2492220C (en) * 2001-07-15 2014-03-18 Keck Graduate Institute Nucleic acid amplification using nicking agents
AU2002365212A1 (en) * 2001-07-15 2003-09-02 Keck Graduate Institute Gene expression analysis using nicking agents
US7297778B2 (en) 2001-07-25 2007-11-20 Affymetrix, Inc. Complexity management of genomic DNA
US6872529B2 (en) * 2001-07-25 2005-03-29 Affymetrix, Inc. Complexity management of genomic DNA
TWI335938B (en) * 2001-08-15 2011-01-11 Rna replication and amplification
US7629152B2 (en) * 2002-03-01 2009-12-08 Integrated Dna Technologies, Inc. Methods for amplifying polymeric nucleic acids
CA2476564C (en) * 2002-03-01 2012-05-15 Integrated Dna Technologies, Inc. Polynomial amplification of nucleic acids
US20030219754A1 (en) * 2002-05-23 2003-11-27 Oleksy Jerome E. Fluorescence polarization detection of nucleic acids
US7108976B2 (en) * 2002-06-17 2006-09-19 Affymetrix, Inc. Complexity management of genomic DNA by locus specific amplification
US9388459B2 (en) * 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
EP1539931A4 (en) 2002-06-27 2006-08-23 Univ Queensland DIFFERENTIATION MODULATION AGENTS AND USES THEREOF
US7459273B2 (en) * 2002-10-04 2008-12-02 Affymetrix, Inc. Methods for genotyping selected polymorphism
EP1567675A4 (en) 2002-11-21 2006-05-10 Epict Technologies METHODS OF USING PRIMERS THAT CODE A STRAND OF A BICATENARY PROMOTER
JP2006508662A (ja) 2002-12-04 2006-03-16 アプレラ コーポレイション ポリヌクレオチドの多重増幅
WO2004058052A2 (en) 2002-12-20 2004-07-15 Applera Corporation Genetic polymorphisms associated with myocardial infarction, methods of detection and uses thereof
US6852494B2 (en) * 2003-01-10 2005-02-08 Linden Technologies, Inc. Nucleic acid amplification
AU2003900481A0 (en) 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
US20100143442A1 (en) 2003-02-05 2010-06-10 Queensland University Of Technology Growth factor complexes and modulation of cell migration and growth
CA2513780C (en) * 2003-02-07 2014-12-30 Diagnocure Inc. Method to detect prostate cancer from a urine sample
US20060192960A1 (en) * 2003-03-24 2006-08-31 Rencs Erik V Polarization detection
AU2003902253A0 (en) 2003-05-12 2003-05-29 The University Of Queensland Method for increasing product yield
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050053980A1 (en) 2003-06-20 2005-03-10 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US8114978B2 (en) * 2003-08-05 2012-02-14 Affymetrix, Inc. Methods for genotyping selected polymorphism
WO2005038039A2 (en) * 2003-10-13 2005-04-28 Genaco Biomedical Products, Inc. Method for multiplex primer based amplification of nucleic acids
CA3048093A1 (en) 2003-11-26 2005-06-23 Celera Corporation Single nucleotide polymorphisms associated with cardiovascular disorders and statin response, methods of detection and uses thereof
US7481997B1 (en) 2004-02-12 2009-01-27 Montana State University Snow mountain virus genome sequence, virus-like particles and methods of use
US20050239889A1 (en) * 2004-04-26 2005-10-27 Jean Gosselin In vivo release of endogenous anti-microbial mediators by leukotriene B4 (LTB4) administration
EP2412826B1 (en) 2004-05-07 2014-01-08 Celera Corporation Genetic polymorphism associated with liver fibrosis methods of detection and uses thereof
EP2412830B1 (en) 2004-07-13 2014-11-19 Gen-Probe Incorporated Compositions and methods for detection of Hepatitis A virus nucleic acid
EP1645640B1 (en) 2004-10-05 2013-08-21 Affymetrix, Inc. Method for detecting chromosomal translocations
EP1833964B1 (en) 2004-12-17 2013-05-22 Monash University Regulation of metalloprotease cleavage of cell surface proteins by adam10
US8883487B2 (en) 2004-12-23 2014-11-11 Abbott Point Of Care Inc. Molecular diagnostics system and methods
CA2491067A1 (en) * 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
US20090070895A1 (en) * 2004-12-24 2009-03-12 Anne Rae Vacuole targeting peptide and nucleic acid
AU2006214179A1 (en) 2005-02-17 2006-08-24 Biogen Idec Ma Inc. Treating neurological disorders
WO2006099365A2 (en) 2005-03-11 2006-09-21 Applera Corporation Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
KR20140068234A (ko) 2005-03-31 2014-06-05 더 제너럴 하스피탈 코포레이션 Hgf/hgfr 활성의 모니터링 및 조정
US7452671B2 (en) * 2005-04-29 2008-11-18 Affymetrix, Inc. Methods for genotyping with selective adaptor ligation
EP2471805A3 (en) 2005-05-06 2013-01-16 Gen-Probe Incorporated Compositions and assays to specifically detect nucleic acid of influenza virus A or B
ATE496996T1 (de) 2005-05-13 2011-02-15 Wako Pure Chem Ind Ltd Primer, sonden, verfahren und verwendungen davon zum nachweis von mycobacterium kansasii
WO2006122401A1 (en) * 2005-05-16 2006-11-23 Institut De Recherches Cliniques De Montreal/I.R.C.M. Negative regulation of nk cell functions by eat-2, a sap-related adaptor expressed in innate immune cells
WO2007030505A1 (en) * 2005-09-06 2007-03-15 Gen-Probe Incorporated Methods, compositions and kits for isothermal amplification of nucleic acids
US7799530B2 (en) 2005-09-23 2010-09-21 Celera Corporation Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof
CA2625414A1 (en) 2005-10-17 2007-04-26 Gen-Probe Incorporated Compositions and methods to detect legionella pneumophila nucleic acid
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
US9234247B2 (en) 2006-03-13 2016-01-12 Wako Pure Chemical Industries, Ltd. Method for detection of mutant gene
US8188256B2 (en) 2006-05-02 2012-05-29 Wako Pure Chemical Industries, Ltd. Primer and probe for detection of Mycobacterium intracellulare
ATE514794T1 (de) * 2006-05-12 2011-07-15 Gen Probe Inc Zusammensetzungen und verfahren für den nachweis von enterokokken-nukleinsäuren
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
WO2008002920A2 (en) * 2006-06-26 2008-01-03 Epoch Biosciences, Inc. Methods for generating target nucleic acid sequences
JP5635772B2 (ja) 2006-08-01 2014-12-03 ジェン−プロウブ インコーポレイテッド 核酸の非特異的標的の捕捉方法
CA2915679C (en) 2006-10-20 2017-12-12 Celera Corporation Genetic polymorphisms associated with venous thrombosis, methods of detection and uses thereof
US9567647B2 (en) 2006-12-18 2017-02-14 Wako Pure Chemical Industries, Ltd. Primer and probe for detection of Mycobacterium avium and method for detection of Mycobacterium avium by using the primer or probe
EP3121286B1 (en) * 2006-12-21 2019-11-20 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
US7695915B2 (en) 2007-01-31 2010-04-13 Celera Corporation Molecular prognostic signature for predicting breast cancer distant metastasis, and uses thereof
US20080293589A1 (en) * 2007-05-24 2008-11-27 Affymetrix, Inc. Multiplex locus specific amplification
AU2008260029B2 (en) 2007-05-31 2015-02-12 Yale University A genetic lesion associated with cancer
WO2008144827A1 (en) 2007-05-31 2008-12-04 The University Of Queensland Diagnostic markers for ankylosing spondylitis and uses thereof
US9689031B2 (en) * 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
US9388457B2 (en) 2007-09-14 2016-07-12 Affymetrix, Inc. Locus specific amplification using array probes
US8039212B2 (en) 2007-11-05 2011-10-18 Celera Corporation Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
CA2715991A1 (en) * 2007-12-26 2009-07-09 Gen-Probe Incorporated Amplification oligomers and methods to detect candida albicans 26s rrna or encoding dna
WO2009099037A1 (ja) 2008-02-08 2009-08-13 Wako Pure Chemical Industries, Ltd. クラミドフィラ・キャビエ検出用プライマー及びプローブ、並びにこれを用いたクラミドフィラ・キャビエの検出方法
US20090221620A1 (en) 2008-02-20 2009-09-03 Celera Corporation Gentic polymorphisms associated with stroke, methods of detection and uses thereof
US20090215050A1 (en) * 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
US9074244B2 (en) 2008-03-11 2015-07-07 Affymetrix, Inc. Array-based translocation and rearrangement assays
EP2284262A4 (en) 2008-05-28 2012-02-22 Wako Pure Chem Ind Ltd PRIMER AND PROBE FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE, AND METHOD FOR DETECTION OF MYCOBACTERIUM INTRACELLULARE USING THE PRIMER OR PROBE
US20110212021A1 (en) 2008-05-30 2011-09-01 Slack Frank J Targeted oligonucleotide compositions for modifying gene expression
EP2733222A1 (en) 2008-07-09 2014-05-21 Celera Corporation Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
US8097412B2 (en) * 2008-07-12 2012-01-17 Biodiagnostics, Inc. DNA-based test for detection of annual and intermediate ryegrass
CN105018548B (zh) 2008-10-24 2019-03-12 阿霹震中科技公司 用于修饰核酸的试剂盒
US9080211B2 (en) 2008-10-24 2015-07-14 Epicentre Technologies Corporation Transposon end compositions and methods for modifying nucleic acids
AU2010217928B2 (en) 2009-02-26 2013-06-06 Gen-Probe Incorporated Assay for detection of human parvovirus nucleic acid
AU2010264468B2 (en) 2009-06-23 2015-01-22 Gen-Probe Incorporated Compositions and methods for detecting nucleic acid from Mollicutes
JP2012531210A (ja) 2009-06-25 2012-12-10 イェール ユニバ−シティ− Brca1における一塩基多型および癌のリスク
WO2011003020A1 (en) 2009-07-01 2011-01-06 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
EP3330385A1 (en) 2009-07-21 2018-06-06 Gen-Probe Incorporated Methods for quantitative detection of nucleic acid sequences over an extended dynamic range
US20110059453A1 (en) * 2009-08-23 2011-03-10 Affymetrix, Inc. Poly(A) Tail Length Measurement by PCR
BR112012013035A8 (pt) 2009-11-30 2018-04-03 Univ Queensland Technology Fibronectina: quimeras do fator do crescimento
WO2011087707A1 (en) 2009-12-22 2011-07-21 Elitech Holding B.V. Hypertheromostable endonuclease iv substrate probe
US20110312503A1 (en) 2010-01-23 2011-12-22 Artemis Health, Inc. Methods of fetal abnormality detection
US9074246B2 (en) 2010-01-25 2015-07-07 Rd Biosciences, Inc. Self-folding amplification of target nucleic acid
CA2785529C (en) * 2010-02-11 2019-01-08 Nanostring Technologies, Inc. Compositions and methods for the detection of small rnas
WO2011103274A1 (en) 2010-02-17 2011-08-25 Gen-Probe Incorporated Compositions and methods to detect atopobium vaginae nucleic acid
WO2011118496A1 (ja) 2010-03-23 2011-09-29 和光純薬工業株式会社 クラミジア・トラコマティス検出用プライマー及びプローブ、並びにこれを用いたクラミジア・トラコマティスの検出方法
US20110269735A1 (en) 2010-04-19 2011-11-03 Celera Corporation Genetic polymorphisms associated with statin response and cardiovascular diseases, methods of detection and uses thereof
WO2011133811A2 (en) 2010-04-21 2011-10-27 Gen-Probe Incorporated Compositions, methods and kits to detect herpes simplex virus nucleic acid
EP3674423A1 (en) 2010-07-12 2020-07-01 Gen-Probe Incorporated Compositions and assays to detect seasonal h3 influenza a virus nucleic acid
US10167508B2 (en) 2010-08-06 2019-01-01 Ariosa Diagnostics, Inc. Detection of genetic abnormalities
US11203786B2 (en) 2010-08-06 2021-12-21 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
US20130261003A1 (en) 2010-08-06 2013-10-03 Ariosa Diagnostics, In. Ligation-based detection of genetic variants
US11031095B2 (en) 2010-08-06 2021-06-08 Ariosa Diagnostics, Inc. Assay systems for determination of fetal copy number variation
US20140342940A1 (en) 2011-01-25 2014-11-20 Ariosa Diagnostics, Inc. Detection of Target Nucleic Acids using Hybridization
US20130040375A1 (en) 2011-08-08 2013-02-14 Tandem Diagnotics, Inc. Assay systems for genetic analysis
US10533223B2 (en) 2010-08-06 2020-01-14 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US8700338B2 (en) 2011-01-25 2014-04-15 Ariosa Diagnosis, Inc. Risk calculation for evaluation of fetal aneuploidy
WO2012030856A2 (en) 2010-08-30 2012-03-08 Gen-Probe Incorporated Compositions, methods and reaction mixtures for the detection of xenotropic murine leukemia virus-related virus
WO2012046219A2 (en) 2010-10-04 2012-04-12 Gen-Probe Prodesse, Inc. Compositions, methods and kits to detect adenovirus nucleic acids
US20120108651A1 (en) 2010-11-02 2012-05-03 Leiden University Medical Center (LUMC) Acting on Behalf of Academic Hospital Leiden (AZL) Genetic polymorphisms associated with venous thrombosis and statin response, methods of detection and uses thereof
US20120190021A1 (en) 2011-01-25 2012-07-26 Aria Diagnostics, Inc. Detection of genetic abnormalities
US10131947B2 (en) 2011-01-25 2018-11-20 Ariosa Diagnostics, Inc. Noninvasive detection of fetal aneuploidy in egg donor pregnancies
US9994897B2 (en) 2013-03-08 2018-06-12 Ariosa Diagnostics, Inc. Non-invasive fetal sex determination
US8756020B2 (en) 2011-01-25 2014-06-17 Ariosa Diagnostics, Inc. Enhanced risk probabilities using biomolecule estimations
US11270781B2 (en) 2011-01-25 2022-03-08 Ariosa Diagnostics, Inc. Statistical analysis for non-invasive sex chromosome aneuploidy determination
US20120219950A1 (en) 2011-02-28 2012-08-30 Arnold Oliphant Assay systems for detection of aneuploidy and sex determination
USRE49975E1 (en) 2011-03-10 2024-05-21 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
US9657352B2 (en) 2011-04-25 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
EP3536809A1 (en) 2011-07-15 2019-09-11 Gen-Probe Incorporated Compositions and method for detecting human parvovirus nucleic acid
US8712697B2 (en) 2011-09-07 2014-04-29 Ariosa Diagnostics, Inc. Determination of copy number variations using binomial probability calculations
WO2013036928A1 (en) 2011-09-08 2013-03-14 Gen-Probe Incorporated Compositions and methods for detecting bv-associated bacterial nucleic acid
US9352312B2 (en) 2011-09-23 2016-05-31 Alere Switzerland Gmbh System and apparatus for reactions
US9518303B2 (en) 2011-10-25 2016-12-13 The Board Of Regents Of The University Of Texas System Methods and compositions for identifying enterovirus
WO2013067413A1 (en) 2011-11-04 2013-05-10 Gen-Probe Incorporated Molecular assay reagents and methods
DE102011120550B4 (de) 2011-12-05 2013-11-07 Gen-Probe Prodesse, Inc. Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren
US11098375B2 (en) 2012-02-24 2021-08-24 Gen-Probe Prodesse, Inc. Detection of Shiga toxin genes in bacteria
AU2013205110B2 (en) 2012-04-24 2016-10-13 Gen-Probe Incorporated Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids
CN104736722B (zh) 2012-05-21 2018-08-07 斯克利普斯研究所 样品制备方法
US10289800B2 (en) 2012-05-21 2019-05-14 Ariosa Diagnostics, Inc. Processes for calculating phased fetal genomic sequences
AU2013205064B2 (en) 2012-06-04 2015-07-30 Gen-Probe Incorporated Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid
AU2013205087B2 (en) 2012-07-13 2016-03-03 Gen-Probe Incorporated Method for detecting a minority genotype
AU2013292287A1 (en) 2012-07-19 2015-02-19 Ariosa Diagnostics, Inc. Multiplexed sequential ligation-based detection of genetic variants
CN104755630B (zh) 2012-08-30 2019-01-11 简·探针公司 多阶段核酸扩增
AU2013205122B2 (en) 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
AU2013205090B2 (en) 2012-12-07 2016-07-28 Gen-Probe Incorporated Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid
CA2897474A1 (en) 2013-01-24 2014-07-31 California Institute Of Technology Chromophore-based characterization and detection methods
US10077475B2 (en) 2013-01-24 2018-09-18 California Institute Of Technology FRET-based analytes detection and related methods and systems
US10975423B2 (en) 2013-03-11 2021-04-13 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
US10590474B2 (en) 2013-03-11 2020-03-17 Elitechgroup B.V. Methods for true isothermal strand displacement amplification
JP2016510991A (ja) 2013-03-11 2016-04-14 エリテックグループ・ベスローテン・フェンノートシャップElitechgroup B.V. 正確な鎖置換型等温増幅のための方法
WO2014140165A1 (en) 2013-03-14 2014-09-18 Dsm Ip Assets B.V. Cell wall deconstruction enzymes of paecilomyces byssochlamydoides and uses thereof
WO2014140167A1 (en) 2013-03-14 2014-09-18 Dsm Ip Assets B.V. Cell wall deconstruction enzymes of malbranchea cinnamomea and uses thereof
AU2014237563B2 (en) 2013-03-15 2020-06-11 Becton, Dickinson And Company Detection of neisseria gonorrhoeaes
CN105074011B (zh) 2013-06-13 2020-10-02 阿瑞奥萨诊断公司 用于非入侵性性染色体非整倍性确定的统计分析
EP4299767A3 (en) 2013-08-14 2024-03-27 Gen-Probe Incorporated Compositions and methods for detecting hev nucleic acid
US10260111B1 (en) 2014-01-20 2019-04-16 Brett Eric Etchebarne Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample
US10017759B2 (en) 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
ES2880335T3 (es) 2014-09-09 2021-11-24 Igenomx Int Genomics Corporation Métodos y composiciones para la preparación rápida de bibliotecas de ácidos nucleicos
US10577649B2 (en) 2014-11-11 2020-03-03 Illumina, Inc. Polynucleotide amplification using CRISPR-Cas systems
SG11201704660YA (en) 2014-12-08 2017-07-28 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
CA2972475C (en) 2015-01-09 2024-01-16 Gen-Probe Incorporated Methods and compositions for diagnosing bacterial vaginosis
US10550438B2 (en) 2015-03-16 2020-02-04 Gen-Probe Incorporated Methods and compositions for detecting bacterial nucleic acid
CN107532219B (zh) * 2015-03-25 2023-05-02 安戈欧洲有限公司 使用链置换聚合酶的固相靶核酸捕获和复制
CN107849603B (zh) 2015-04-24 2022-01-28 阿提拉生物系统公司 利用有限核苷酸组成的引物扩增
EP4166678B1 (en) 2015-04-24 2024-05-29 Becton, Dickinson and Company Multiplex detection of vulvovaginal candidiasis, trichomoniasis and bacterial vaginosis
CN108779499B (zh) 2016-01-04 2023-08-11 简·探针公司 用于检测念珠菌属物种的方法和组合物
JP2019503176A (ja) 2016-01-12 2019-02-07 インターロイキン ジェネティクス, インコーポレイテッド 処置に対する応答を予測するための方法
US9771623B1 (en) 2016-03-15 2017-09-26 The Board Of Regents Of The University Of Texas System Molecular typing system for flavivirus diagnostics
CN109477137B (zh) 2016-05-11 2023-05-30 伊鲁米那股份有限公司 使用argonaute系统的多核苷酸富集和扩增
WO2017205957A1 (en) 2016-06-01 2017-12-07 9087-4405 Quebec Inc. Remote access system and method for plant pathogen management
US11098360B2 (en) 2016-06-01 2021-08-24 Roche Sequencing Solutions, Inc. Immuno-PETE
US10508312B2 (en) 2016-06-10 2019-12-17 Gen-Probe Incorporated Compositions and methods for detecting Zika virus nucleic acid
MA45491A (fr) 2016-06-27 2019-05-01 Juno Therapeutics Inc Épitopes à restriction cmh-e, molécules de liaison et procédés et utilisations associés
CA3028002A1 (en) 2016-06-27 2018-01-04 Juno Therapeutics, Inc. Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
JP7167013B2 (ja) 2016-10-19 2022-11-08 ジェン-プローブ・インコーポレーテッド C型肝炎ウイルスを検出または定量するための組成物および方法
WO2018094171A1 (en) 2016-11-21 2018-05-24 Gen-Probe Incorporated Compositions and methods for detecting or quantifying hepatitis b virus
EP4095263A1 (en) 2017-01-06 2022-11-30 Editas Medicine, Inc. Methods of assessing nuclease cleavage
US10337070B2 (en) 2017-01-12 2019-07-02 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
EP4282985A3 (en) 2017-03-24 2024-02-28 Gen-Probe Incorporated Compositions and methods for detecting or quantifying parainfluenza virus
CA3225653A1 (en) 2017-03-25 2018-10-04 Gen-Probe Incorporated Methods and compositions to detect rhinovirus nucleic acids
US20200165599A1 (en) 2017-05-11 2020-05-28 Gen-Probe Incorporated Compositions and Methods for Isolating Target Nucleic Acids
CA3063283A1 (en) 2017-05-17 2018-11-22 Microbio Pty Ltd Methods and agents for identifying or classifying microbes based on polymorphisms within ribosomal rna genes
US10914729B2 (en) 2017-05-22 2021-02-09 The Trustees Of Princeton University Methods for detecting protein binding sequences and tagging nucleic acids
EP3635140B1 (en) 2017-06-07 2023-05-31 Gen-Probe Incorporated Detecting babesia species nucleic acid in a sample
EP4289507A3 (en) 2017-07-10 2024-02-28 Gen-Probe Incorporated Analytical systems and methods for nucleic acid amplification using sample assigning parameters
CN111094595A (zh) 2017-08-11 2020-05-01 简·探针公司 用于检测金黄色葡萄球菌的组合物和方法
WO2019089982A1 (en) 2017-11-01 2019-05-09 Juno Therapeutics, Inc. Method of assessing activity of recombinant antigen receptors
JP7068451B2 (ja) 2017-11-17 2022-05-16 ジェン-プローブ・インコーポレーテッド C1orf43核酸を検出するための組成物および方法
WO2019118550A1 (en) 2017-12-13 2019-06-20 Gen-Probe Incorporated Methods for biological sample processing
JP2021506274A (ja) 2017-12-15 2021-02-22 ジェン−プローブ・インコーポレーテッド 毒素産生Clostridium difficileを検出するための組成物および方法
WO2019121842A1 (en) * 2017-12-21 2019-06-27 F. Hoffmann-La Roche Ag Target enrichment by unidirectional dual probe primer extension
WO2019148169A1 (en) 2018-01-29 2019-08-01 Gen-Probe Incorporated Analytical systems and methods
GB2597570B (en) 2018-06-13 2022-11-23 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
JP7470095B2 (ja) 2018-07-10 2024-04-17 ジェン-プローブ・インコーポレーテッド 核酸を検出および定量するための方法およびシステム
AU2019314449A1 (en) 2018-08-01 2021-03-11 Gen-Probe Incorporated Compositions and methods for detecting nucleic acids of Epstein-Barr virus
WO2020033557A1 (en) 2018-08-08 2020-02-13 Gen-Probe Incorporated Compositions, methods and kits for detecting mycoplasma genitalium
CA3107043A1 (en) 2018-08-21 2020-02-27 Gen-Probe Incorporated Compositions and methods for amplifying, detecting or quantifying human cytomegalovirus
AU2019324196A1 (en) 2018-08-24 2021-03-18 Gen-Probe Incorporated Compositions and methods for detecting bacterial nucleic acid and diagnosing bacterial vaginosis
US11066691B1 (en) 2018-09-14 2021-07-20 National Technology & Engineering Solutions Of Sandia, Llc Therapeutic phages and methods thereof
WO2020069085A2 (en) 2018-09-27 2020-04-02 Gen-Probe Incorporated Compositions and methods for detecting bordetella pertussis and bordetella parapertussis nucleic acid
AU2019351824A1 (en) 2018-10-01 2021-05-27 Gen-Probe Incorporated Compositions and methods for amplifying or detecting varicella-zoster virus
CN113195743A (zh) 2018-10-22 2021-07-30 简·探针公司 扩增,检测或定量人类多瘤病毒bk病毒的组合物和方法
TW202030333A (zh) 2018-12-20 2020-08-16 美商簡 探針公司 用於檢測瘧原蟲物種核酸之組成物及方法
WO2020142347A2 (en) 2018-12-31 2020-07-09 Gen-Probe Incorporated Systems and methods for filling multi-well cartridges with solid reagents
US20220098647A1 (en) 2019-03-22 2022-03-31 Gen-Probe Incorporated Compositions and Methods for Detecting Group A Streptococcus
CN114127312A (zh) 2019-04-30 2022-03-01 拉利玛生物医药公司 用于测定共济蛋白替代疗法的疗效的共济蛋白敏感性标志物
EP4371667A3 (en) 2019-05-03 2024-07-31 Gen-Probe Incorporated Receptacle transport system for an analytical system
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
EP3994284A1 (en) 2019-07-03 2022-05-11 Gen-Probe Incorporated Oligonucleotides for use in determining the presence of trichomonas vaginalis in a sample
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
US20220298548A1 (en) 2019-08-23 2022-09-22 Gen-Probe Incorporated Compositions, methods and kits for detecting treponema pallidum
JP7556945B2 (ja) 2019-09-05 2024-09-26 ジェン-プローブ・インコーポレーテッド Chlamydia trachomatis変異体の核酸の検出
WO2021080629A1 (en) 2019-10-23 2021-04-29 Elitechgroup, Inc. Methods for true isothermal strand displacement amplification
WO2021097358A1 (en) 2019-11-14 2021-05-20 Gen-Probe Incorporated Compositions and methods for capturing target nucleic acids
EP4342999A3 (en) 2020-01-16 2024-04-24 DNAe Diagnostics Limited Compositions, kits and methods for isolating target polynucleotides
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19
US20230220499A1 (en) 2020-05-07 2023-07-13 Grifols Diagnostic Solutions Inc. Methods and compositions for detecting sars-cov-2 nucleic acid
US20230243001A1 (en) 2020-07-17 2023-08-03 Gen-Probe Incorporated Detection of Macrolide-Resistant Mycoplasma Genitalium
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
US20230393163A1 (en) 2020-10-21 2023-12-07 Gen-Probe Incorporated Fluid container management system
KR20230097079A (ko) 2020-11-05 2023-06-30 백톤 디킨슨 앤드 컴퍼니 비브리오 파라헤몰리티쿠스의 신속 확인 및 형결정
US20230407412A1 (en) 2020-11-05 2023-12-21 Becton, Dickinson And Company Multiplex detection of bacterial respiratory pathogens
KR20230097044A (ko) 2020-11-05 2023-06-30 백톤 디킨슨 앤드 컴퍼니 비브리오 콜레라에의 멀티플렉스 검출 및 형결정
EP4305163A1 (en) 2021-03-09 2024-01-17 Illumina, Inc. Genomic library preparation and targeted epigenetic assays using cas-grna ribonucleoproteins
CA3209070A1 (en) 2021-03-09 2022-09-22 Hongxia Xu Analyzing expression of protein-coding variants in cells
WO2022197634A1 (en) 2021-03-15 2022-09-22 Gen-Probe Incorporated Compositions and methods for biological sample processing
US20240230651A1 (en) 2021-04-06 2024-07-11 Bpgbio, Inc. Protein markers for the prognosis of breast cancer progression
WO2022216841A1 (en) 2021-04-06 2022-10-13 Berg Llc Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
CA3214821A1 (en) 2021-04-06 2022-10-13 Guisong WANG Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
US20240254572A1 (en) 2021-07-01 2024-08-01 Gen-Probe Incorporated Enzyme formulations and reaction mixtures for nucleic acid amplification
GB202110485D0 (en) 2021-07-21 2021-09-01 Dnae Diagnostics Ltd Compositions, kits and methods for sequencing target polynucleotides
JP2024526921A (ja) 2021-07-21 2024-07-19 ディーエヌエイイー ダイアグノスティックス リミテッド 標的ポリヌクレオチドを配列決定するための組成物、キット及び方法
GB202110479D0 (en) 2021-07-21 2021-09-01 Dnae Diagnostics Ltd Compositions, kits and methods for sequencing target polynucleotides
AU2022319876A1 (en) 2021-07-27 2024-01-18 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal pathogens
EP4384634A1 (en) 2021-08-11 2024-06-19 Illumina, Inc. Detection of analytes using targeted epigenetic assays, proximity-induced tagmentation, strand invasion, restriction, or ligation
WO2023049708A1 (en) 2021-09-22 2023-03-30 Herbalife International Of America, Inc. Methods and compositions for identifying botanical material using arms-pcr
WO2023196937A1 (en) 2022-04-06 2023-10-12 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring frataxin replacement therapy
EP4282980A1 (en) 2022-05-23 2023-11-29 Mobidiag Oy Methods for amplifying a nucleic acid
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
WO2024054924A1 (en) 2022-09-08 2024-03-14 Gen-Probe Incorporated Method of detecting nucleic acid analytes using dual-specificity primers
WO2024081776A1 (en) 2022-10-13 2024-04-18 Gen-Probe Incorporated Cellularity control for nucleic acid assays
EP4389911A1 (en) 2022-12-21 2024-06-26 Mobidiag Oy Methods and systems for isolating an analyte
EP4389887A1 (en) 2022-12-21 2024-06-26 Mobidiag Oy Isolating and lysing cells
WO2024161179A1 (en) 2023-01-31 2024-08-08 Mobidiag Oy Compositions and methods for detecting stx nucleic acids
EP4454758A1 (en) 2023-04-28 2024-10-30 Mobidiag Oy Nucleic acid amplification process controls
EP4455303A1 (en) 2023-04-28 2024-10-30 Mobidiag Oy Nucleic acid amplification process controls
EP4455304A1 (en) 2023-04-28 2024-10-30 Mobidiag Oy Nucleic acid amplification process controls

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
WO1990001064A1 (en) * 1988-07-26 1990-02-08 Genelabs Incorporated Sequence-specific amplification techniques
GB8818020D0 (en) * 1988-07-28 1988-09-01 Ici Plc Method for amplification of nucleotide sequences
CA1339731C (en) * 1988-10-12 1998-03-17 Charles T. Caskey Multiplex genomic dna amplification for deletion detection
DE69028325T2 (de) * 1989-01-19 1997-04-17 Behringwerke Ag Nukleinsäure-Amplifikation unter Verwendung eines Einzelprimers
EP0458909A1 (en) * 1989-02-14 1991-12-04 Biogen, Inc. Oligonucleotide primer pairs for sequence independent gene amplification and methods which employ them
US5104792A (en) * 1989-12-21 1992-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method for amplifying unknown nucleic acid sequences
GB9011454D0 (en) * 1990-05-22 1990-07-11 Medical Res Council Polynucleotide amplification
US5595891A (en) * 1990-07-19 1997-01-21 Behringwerke Ag Method for producing a polynucleotide for use in single primer amplification
US5455166A (en) * 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
ZA927323B (en) * 1991-09-24 1993-08-30 Keygene Nv Selective restriction fragment amplification: A general method for DNA fingerprinting

Also Published As

Publication number Publication date
DE69412540T2 (de) 1998-12-24
EP0628640B1 (en) 1998-08-19
DE69412540D1 (de) 1998-09-24
AU6453794A (en) 1994-12-08
CA2125004A1 (en) 1994-12-05
AU673424B2 (en) 1996-11-07
EP0628640A1 (en) 1994-12-14
BR9402174A (pt) 1995-03-07
US5624825A (en) 1997-04-29
SG52767A1 (en) 1998-09-28
CA2125004C (en) 2001-12-18
JPH0819394A (ja) 1996-01-23
US5422252A (en) 1995-06-06
JP2703183B2 (ja) 1998-01-26
MX9404063A (es) 1995-01-31

Similar Documents

Publication Publication Date Title
ES2122083T3 (es) Amplificacion simultanea de multiples dianas.
DE3750422D1 (de) Translation von mrna.
CY1119742T1 (el) Βιολογικα συστηματα μεταφορας πολλαπλου-συστατικου
IS3101A7 (is) Fiskflutningakerfi.
DK0567635T3 (da) Hurtige assays for amplifikationsprodukter
NO950381D0 (no) Nukleinsyresekvens amplifikasjon
EA199900598A1 (ru) Производные 1-арил- и пиридилпиразола с пестицидными свойствами
BR8807104A (pt) Processo para preservacao de folhas,transplantaveis,de epitelio,cultivadas in vitro
GR1000118B (el) Συνθεσις 1,2-διοξετανων & ενδιαμεσαι ουσιαι δι αυτην.
EP0887924A3 (en) High efficiency RF amplifier
DE3866204D1 (de) Antriebswelle mit gruppenweise darauf befestigten antriebselementen.
DK449988D0 (da) Farmaceutisk praeparat med dobbeltstrenget rna
ATE243705T1 (de) Nukleosid analogen
DK0507369T3 (da) Kloning og ekspression af acetylxylanesteraser af fungal oprindelse
DK187087A (da) Aksialventilatorhjul
ATE207751T1 (de) Verbesserungen bezüglich langwirksamer antibiotika
PT84181B (pt) Processo para a preparacao de derivados de benzazecina e de composicoes farmaceuticas que os comtem
ES2100863T3 (es) Procedimiento para la preparacion de acidos nucleicos modificados.
GR900100060A (el) Συν?έσεις αναστολής της λιποξυγενάσης.
DE59707636D1 (de) Stabile, kaltwasser-dispergierbare Präparate
ES2065122T3 (es) Estanteria para tiendas.
SE7711433L (sv) Tricykliska foreningar
SE9603145L (sv) Fordonsram samt sätt att montera densamma
DE59501234D1 (de) Verfahren zur Herstellung von 2-Nitrobenzaldehyden
DE3854064D1 (de) Hydrochinonylphenyl-Buttersäureamid-Derivate.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 628640

Country of ref document: ES