ES2009099A6 - Procedimiento para preparar polinucleotidos. - Google Patents
Procedimiento para preparar polinucleotidos.Info
- Publication number
- ES2009099A6 ES2009099A6 ES8803317A ES8803317A ES2009099A6 ES 2009099 A6 ES2009099 A6 ES 2009099A6 ES 8803317 A ES8803317 A ES 8803317A ES 8803317 A ES8803317 A ES 8803317A ES 2009099 A6 ES2009099 A6 ES 2009099A6
- Authority
- ES
- Spain
- Prior art keywords
- preparing polynucleotides
- resin
- sulfurate
- sula
- pyrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000006166 lysate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- 239000002510 pyrogen Substances 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878725606A GB8725606D0 (en) | 1987-11-02 | 1987-11-02 | Preparation polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2009099A6 true ES2009099A6 (es) | 1989-08-16 |
Family
ID=10626275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8803317A Expired ES2009099A6 (es) | 1987-11-02 | 1988-10-31 | Procedimiento para preparar polinucleotidos. |
Country Status (29)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9108085D0 (en) * | 1991-04-16 | 1991-06-05 | Scras | Complexes of polyadenylic acid with polyuridylic acid |
| TW589189B (en) * | 1997-08-04 | 2004-06-01 | Scras | Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis |
| EP2258712A3 (en) * | 2002-03-15 | 2011-05-04 | Multicell Immunotherapeutics, Inc. | Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs |
| EP1582584A4 (en) * | 2002-12-26 | 2006-05-31 | Nippon Shinyaku Co Ltd | PROCESS FOR PRODUCING PNPASE |
| JP2007516729A (ja) * | 2003-12-30 | 2007-06-28 | シグマ−アルドリッチ・カンパニー | 酵素消化による核酸の迅速な調製 |
| AU2009239655B2 (en) | 2008-04-25 | 2014-05-22 | Innate Pharma | Improved TLR3 agonist compositions |
| US20120171729A1 (en) * | 2010-12-30 | 2012-07-05 | Ibis Biosciences, Inc. | Methods for the synthesis of polyadenylic acid |
| MX2022009001A (es) | 2020-01-24 | 2022-10-27 | Aim Immunotech Inc | Arn bicatenario terapéutico y métodos para producirlo. |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU6012A1 (ru) * | 1927-04-04 | 1928-07-31 | Л.С. Кравцов | Горизонтальный вод ной двигатель с поворотными лопаст ми |
| JPS4940954B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1970-02-16 | 1974-11-06 | ||
| DE2056081A1 (en) * | 1970-11-14 | 1972-06-22 | Pabst Brewing Company, Milwaukee, Wis. (V.StA.) | Poly nucleotides prepn |
| IL37076A (en) * | 1971-06-16 | 1974-05-16 | Littauer U | A method for stepwise synthesis of oligoribonucleotides of defined sequence using 2'(3')-o-acyl-nucleoside diphosphates and polynucleotide phosphorylase |
| JPS524633B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-07-21 | 1977-02-05 | ||
| GB1435571A (en) * | 1973-04-02 | 1976-05-12 | Searle & Co | Polynucleotides |
| DE2319495C2 (de) * | 1973-04-17 | 1985-01-10 | Yeda Research And Development Co., Ltd., Rehovot | Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule |
| FR2252350A1 (en) * | 1973-11-22 | 1975-06-20 | Choay Sa | Polynucleotide phosphorylase - extraction from E coli, fixation on sepharose, and use in preparing polynucleotides |
| JPS50107187A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1974-02-08 | 1975-08-23 | ||
| US4006059A (en) * | 1974-07-29 | 1977-02-01 | Purdue Research Foundation | Hydrophobic noncovalent binding of proteins to support materials |
| US4000098A (en) * | 1974-08-16 | 1976-12-28 | Palo Alto Medical Research Foundation | Separation of proteins by hydrophobic adsorption |
| SU601287A1 (ru) * | 1976-05-12 | 1978-04-05 | Предприятие П/Я М-5043 | Способ получени полирибонуклеотидов |
| US4075195A (en) * | 1976-08-31 | 1978-02-21 | Kraft, Inc. | Debittered protein product and method for manufacture |
| SU619508A1 (ru) * | 1976-12-07 | 1978-08-15 | Предприятие П/Я Г-4740 | Способ получени полинуклеотидов, обладающих полирибонуклеотидфосфорилазной активностью |
| JPS5922518B2 (ja) * | 1977-03-09 | 1984-05-26 | 三菱化学株式会社 | ポリグアニル酸の製造方法 |
| JPS5618597A (en) * | 1979-07-23 | 1981-02-21 | Mitsubishi Chem Ind Ltd | Production of oligonucleotide |
| US4379843A (en) * | 1981-01-26 | 1983-04-12 | Peter Cashion | Immobilization of polynucleotides and polypeptides with tritylated polysaccharides |
| US4617376A (en) * | 1985-07-01 | 1986-10-14 | Eli Lilly And Company | Process for recovering glucagon from pancreas glands |
| US4771128A (en) * | 1986-10-10 | 1988-09-13 | Cetus Corporation | Method of purifying toxin conjugates using hydrophobic interaction chromatography |
-
1987
- 1987-11-02 GB GB878725606A patent/GB8725606D0/en active Pending
-
1988
- 1988-10-20 NZ NZ226643A patent/NZ226643A/en unknown
- 1988-10-24 AR AR88312284A patent/AR244342A1/es active
- 1988-10-24 CH CH3951/88A patent/CH676248A5/fr not_active IP Right Cessation
- 1988-10-25 NL NL8802617A patent/NL194949C/nl not_active IP Right Cessation
- 1988-10-26 GR GR880100728A patent/GR1000715B/el not_active IP Right Cessation
- 1988-10-28 AU AU24429/88A patent/AU610792B2/en not_active Ceased
- 1988-10-28 BE BE8801243A patent/BE1001938A4/fr not_active IP Right Cessation
- 1988-10-28 MY MYPI88001231A patent/MY103445A/en unknown
- 1988-10-31 ES ES8803317A patent/ES2009099A6/es not_active Expired
- 1988-10-31 SE SE8803930A patent/SE503401C2/sv not_active IP Right Cessation
- 1988-10-31 AT AT0267788A patent/AT396251B/de not_active IP Right Cessation
- 1988-10-31 GB GB8825399A patent/GB2211847B/en not_active Expired - Lifetime
- 1988-10-31 PT PT88903A patent/PT88903B/pt not_active IP Right Cessation
- 1988-10-31 IT IT8822471A patent/IT1227447B/it active
- 1988-11-01 NO NO884865A patent/NO172902C/no unknown
- 1988-11-01 CA CA000581851A patent/CA1339911C/en not_active Expired - Fee Related
- 1988-11-01 ZA ZA888180A patent/ZA888180B/xx unknown
- 1988-11-01 DK DK607388A patent/DK607388A/da not_active Application Discontinuation
- 1988-11-01 KR KR1019880014332A patent/KR0134624B1/ko not_active Expired - Fee Related
- 1988-11-01 IE IE329088A patent/IE61610B1/en not_active IP Right Cessation
- 1988-11-01 US US07/265,561 patent/US4927755A/en not_active Expired - Lifetime
- 1988-11-02 FR FR888814252A patent/FR2622586B1/fr not_active Expired - Lifetime
- 1988-11-02 FR FR888814251A patent/FR2622451B1/fr not_active Expired - Lifetime
- 1988-11-02 TN TNTNSN88113A patent/TNSN88113A1/fr unknown
- 1988-11-02 DE DE3837203A patent/DE3837203A1/de active Granted
- 1988-11-02 FI FI885045A patent/FI95135C/fi not_active IP Right Cessation
- 1988-11-02 JP JP63276359A patent/JPH0712316B2/ja not_active Expired - Fee Related
- 1988-11-18 OA OA59474A patent/OA10206A/fr unknown
-
1992
- 1992-04-14 SG SG407/92A patent/SG40792G/en unknown
- 1992-07-02 HK HK476/92A patent/HK47692A/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20100528 |