FR2622586B1 - Nouveau procede de preparation des polynucleotides ainsi que les produits obtenus selon ce procede - Google Patents

Nouveau procede de preparation des polynucleotides ainsi que les produits obtenus selon ce procede

Info

Publication number
FR2622586B1
FR2622586B1 FR888814252A FR8814252A FR2622586B1 FR 2622586 B1 FR2622586 B1 FR 2622586B1 FR 888814252 A FR888814252 A FR 888814252A FR 8814252 A FR8814252 A FR 8814252A FR 2622586 B1 FR2622586 B1 FR 2622586B1
Authority
FR
France
Prior art keywords
polynucleotides
preparation
obtained according
products obtained
new process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR888814252A
Other languages
English (en)
Other versions
FR2622586A1 (fr
Inventor
Pierre-Etienne Cha Lassauniere
Acaye Soudhir Colote
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of FR2622586A1 publication Critical patent/FR2622586A1/fr
Application granted granted Critical
Publication of FR2622586B1 publication Critical patent/FR2622586B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • Y10S435/815Enzyme separation or purification by sorption

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR888814252A 1987-11-02 1988-11-02 Nouveau procede de preparation des polynucleotides ainsi que les produits obtenus selon ce procede Expired - Fee Related FR2622586B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878725606A GB8725606D0 (en) 1987-11-02 1987-11-02 Preparation polynucleotides

Publications (2)

Publication Number Publication Date
FR2622586A1 FR2622586A1 (fr) 1989-05-05
FR2622586B1 true FR2622586B1 (fr) 1992-02-21

Family

ID=10626275

Family Applications (2)

Application Number Title Priority Date Filing Date
FR888814251A Expired - Fee Related FR2622451B1 (fr) 1987-11-02 1988-11-02 Compositions therapeutiques a base de polynucleotides
FR888814252A Expired - Fee Related FR2622586B1 (fr) 1987-11-02 1988-11-02 Nouveau procede de preparation des polynucleotides ainsi que les produits obtenus selon ce procede

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR888814251A Expired - Fee Related FR2622451B1 (fr) 1987-11-02 1988-11-02 Compositions therapeutiques a base de polynucleotides

Country Status (29)

Country Link
US (1) US4927755A (fr)
JP (1) JPH0712316B2 (fr)
KR (1) KR0134624B1 (fr)
AR (1) AR244342A1 (fr)
AT (1) AT396251B (fr)
AU (1) AU610792B2 (fr)
BE (1) BE1001938A4 (fr)
CA (1) CA1339911C (fr)
CH (1) CH676248A5 (fr)
DE (1) DE3837203A1 (fr)
DK (1) DK607388A (fr)
ES (1) ES2009099A6 (fr)
FI (1) FI95135C (fr)
FR (2) FR2622451B1 (fr)
GB (2) GB8725606D0 (fr)
GR (1) GR1000715B (fr)
HK (1) HK47692A (fr)
IE (1) IE61610B1 (fr)
IT (1) IT1227447B (fr)
MY (1) MY103445A (fr)
NL (1) NL194949C (fr)
NO (1) NO172902C (fr)
NZ (1) NZ226643A (fr)
OA (1) OA10206A (fr)
PT (1) PT88903B (fr)
SE (1) SE503401C2 (fr)
SG (1) SG40792G (fr)
TN (1) TNSN88113A1 (fr)
ZA (1) ZA888180B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
TW589189B (en) * 1997-08-04 2004-06-01 Scras Kit containing at least one double-stranded RNA combined with at least one anti-viral agent for therapeutic use in the treatment of a viral disease, notably of viral hepatitis
EP2258712A3 (fr) * 2002-03-15 2011-05-04 Multicell Immunotherapeutics, Inc. Compositions et procédés permettant d'initier ou d'ameliorer les réponses des cellules T limitées par le complexe majeur d 'histocompatibilité de classe I ou II et un anticorps au moyen de motifs d'ARN non codants immunomodulateurs
US20060166315A1 (en) * 2002-12-26 2006-07-27 Masatoshi Murai Process for producing pnpase
JP2007516729A (ja) * 2003-12-30 2007-06-28 シグマ−アルドリッチ・カンパニー 酵素消化による核酸の迅速な調製
US20110076296A1 (en) 2008-04-25 2011-03-31 Innate Pharma S.A. TLR3 Agonist Compositions
US20120171729A1 (en) * 2010-12-30 2012-07-05 Ibis Biosciences, Inc. Methods for the synthesis of polyadenylic acid
EP4093407A4 (fr) * 2020-01-24 2024-07-17 Aim Immunotech Inc Arn à double brin thérapeutique et leurs procédés de fabrication

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU6012A1 (ru) * 1927-04-04 1928-07-31 Л.С. Кравцов Горизонтальный вод ной двигатель с поворотными лопаст ми
JPS4940954B1 (fr) * 1970-02-16 1974-11-06
DE2056081A1 (en) * 1970-11-14 1972-06-22 Pabst Brewing Company, Milwaukee, Wis. (V.StA.) Poly nucleotides prepn
IL37076A (en) * 1971-06-16 1974-05-16 Littauer U A method for stepwise synthesis of oligoribonucleotides of defined sequence using 2'(3')-o-acyl-nucleoside diphosphates and polynucleotide phosphorylase
JPS524633B2 (fr) * 1972-07-21 1977-02-05
GB1435571A (en) * 1973-04-02 1976-05-12 Searle & Co Polynucleotides
DE2319495C2 (de) * 1973-04-17 1985-01-10 Yeda Research And Development Co., Ltd., Rehovot Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule
FR2252350A1 (en) * 1973-11-22 1975-06-20 Choay Sa Polynucleotide phosphorylase - extraction from E coli, fixation on sepharose, and use in preparing polynucleotides
JPS50107187A (fr) * 1974-02-08 1975-08-23
US4006059A (en) * 1974-07-29 1977-02-01 Purdue Research Foundation Hydrophobic noncovalent binding of proteins to support materials
US4000098A (en) * 1974-08-16 1976-12-28 Palo Alto Medical Research Foundation Separation of proteins by hydrophobic adsorption
SU601287A1 (ru) * 1976-05-12 1978-04-05 Предприятие П/Я М-5043 Способ получени полирибонуклеотидов
US4075195A (en) * 1976-08-31 1978-02-21 Kraft, Inc. Debittered protein product and method for manufacture
SU619508A1 (ru) * 1976-12-07 1978-08-15 Предприятие П/Я Г-4740 Способ получени полинуклеотидов, обладающих полирибонуклеотидфосфорилазной активностью
JPS5922518B2 (ja) * 1977-03-09 1984-05-26 三菱化学株式会社 ポリグアニル酸の製造方法
JPS5618597A (en) * 1979-07-23 1981-02-21 Mitsubishi Chem Ind Ltd Production of oligonucleotide
US4379843A (en) * 1981-01-26 1983-04-12 Peter Cashion Immobilization of polynucleotides and polypeptides with tritylated polysaccharides
US4617376A (en) * 1985-07-01 1986-10-14 Eli Lilly And Company Process for recovering glucagon from pancreas glands
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography

Also Published As

Publication number Publication date
GB8825399D0 (en) 1988-11-30
HK47692A (en) 1992-07-10
CA1339911C (fr) 1998-06-16
FI95135B (fi) 1995-09-15
JPH0712316B2 (ja) 1995-02-15
SE8803930D0 (sv) 1988-10-31
KR0134624B1 (ko) 1998-04-20
FI885045A (fi) 1989-05-03
PT88903B (pt) 1993-02-26
JPH01148196A (ja) 1989-06-09
NZ226643A (en) 1990-11-27
DK607388D0 (da) 1988-11-01
DE3837203C2 (fr) 1991-08-08
AT396251B (de) 1993-07-26
OA10206A (fr) 1997-01-16
IE883290L (en) 1989-05-02
NL8802617A (nl) 1989-06-01
IT8822471A0 (it) 1988-10-31
DE3837203A1 (de) 1989-05-11
PT88903A (pt) 1988-11-01
IT1227447B (it) 1991-04-11
FR2622451A1 (fr) 1989-05-05
AU610792B2 (en) 1991-05-23
BE1001938A4 (fr) 1990-04-17
SE8803930L (sv) 1989-05-03
US4927755A (en) 1990-05-22
AR244342A1 (es) 1993-10-29
KR890008163A (ko) 1989-07-10
DK607388A (da) 1989-05-03
SE503401C2 (sv) 1996-06-10
TNSN88113A1 (fr) 1990-07-10
ZA888180B (en) 1989-07-26
GB2211847B (en) 1992-01-22
GB2211847A (en) 1989-07-12
NL194949C (nl) 2003-08-04
GR1000715B (el) 1992-11-23
CH676248A5 (fr) 1990-12-28
ATA267788A (de) 1992-11-15
NO884865D0 (no) 1988-11-01
GB8725606D0 (en) 1987-12-09
AU2442988A (en) 1989-05-04
NO884865L (no) 1989-05-03
NO172902B (no) 1993-06-14
SG40792G (en) 1992-06-12
MY103445A (en) 1993-06-30
IE61610B1 (en) 1994-11-16
FR2622586A1 (fr) 1989-05-05
FR2622451B1 (fr) 1992-02-21
FI885045A0 (fi) 1988-11-02
FI95135C (fi) 1995-12-27
ES2009099A6 (es) 1989-08-16
NO172902C (no) 1993-09-22
NL194949B (nl) 2003-04-01

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Legal Events

Date Code Title Description
ST Notification of lapse