EP3111869B1 - System zum versiegeln einer aifblasbaren prothese - Google Patents

System zum versiegeln einer aifblasbaren prothese Download PDF

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Publication number
EP3111869B1
EP3111869B1 EP16177165.4A EP16177165A EP3111869B1 EP 3111869 B1 EP3111869 B1 EP 3111869B1 EP 16177165 A EP16177165 A EP 16177165A EP 3111869 B1 EP3111869 B1 EP 3111869B1
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EP
European Patent Office
Prior art keywords
prosthesis
tube
expandable
optionally
plug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP16177165.4A
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English (en)
French (fr)
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EP3111869A1 (de
Inventor
Shaul Shohat
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Ortho Space Ltd
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Ortho Space Ltd
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Publication of EP3111869A1 publication Critical patent/EP3111869A1/de
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/562Implants for placement in joint gaps without restricting joint motion, e.g. to reduce arthritic pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/40Joints for shoulders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7061Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant for stabilising vertebrae or discs by improving the condition of their tissues, e.g. using implanted medication or fluid exchange
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7097Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72Intramedullary pins, nails or other devices
    • A61B17/7233Intramedullary pins, nails or other devices with special means of locking the nail to the bone
    • A61B17/7258Intramedullary pins, nails or other devices with special means of locking the nail to the bone with laterally expanding parts, e.g. for gripping the bone
    • A61B17/7275Intramedullary pins, nails or other devices with special means of locking the nail to the bone with laterally expanding parts, e.g. for gripping the bone with expanding cylindrical parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/885Tools for expanding or compacting bones or discs or cavities therein
    • A61B17/8852Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc
    • A61B17/8855Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc inflatable, e.g. kyphoplasty balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802Equipment for handling bone cement or other fluid fillers
    • A61B17/8805Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00535Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
    • A61B2017/00557Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0003Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having an inflatable pocket filled with fluid, e.g. liquid or gas

Definitions

  • the present inventions relate generally to the field of medical devices and the treatment of human medical conditions using the medical devices. More specifically, the present inventions include expandable prosthetic devices used for treating a variety of conditions, including rotator cuff injuries, broken and/or depressed bone fractures, infection and/or inflammation in the body.
  • expandable prosthetic devices used for treating a variety of conditions, including rotator cuff injuries, broken and/or depressed bone fractures, infection and/or inflammation in the body.
  • the invention is defined in claim 1.
  • An aspect of some embodiments of the invention relates to prostheses adapted to reduce injuries between soft tissues of the body and other tissues.
  • soft tissues are for example, tendons and/or ligaments.
  • other tissues are, for example, bones.
  • the prosthesis is expandable.
  • the prosthesis is elastic.
  • the prosthesis is rigid.
  • the prosthesis is shaped and/or sized to simulate a bursa naturally occurring in the body.
  • the bursa simulated is the one expected to be present at the implantation site of the prosthesis in a healthy patient.
  • the member is expandable.
  • the member is adapted to be at least partially inflated.
  • the member is inflated sufficiently to reduce rubbing of the soft tissues against other tissues while permitting at least some movement of the soft tissues relative to the other tissues.
  • at least some movement of the soft tissues relative to the other tissues is full movement.
  • the member is sponge-like.
  • the sponge-like member is provided with a fluid absorbent material which when fluids are absorbed induces expansion of the sponge-like expandable member.
  • the prosthesis is constructed of at least one non-biodegradable material.
  • the at least one non-biodegradable material is polyethylene, polyurethane, silicon, or poly-paraphenylene terephthalamide.
  • the member is contoured to act as a counterpart to natural anatomical features of an implantation site.
  • a system for sealing an inflatable prosthesis comprising: a prosthesis inflation device; a tube operatively connected to the prosthesis near one end and the prosthesis inflation device on the other end; a plug attached to the tube at the prosthesis end of the tube ; and, a rigid ring attached to the prosthesis and slidably attached around the tube between the prosthesis inflation device and the plug; wherein pulling the tube towards the prosthesis inflation device causes plug to lodge in the rigid ring, sealing the prosthesis with the plug.
  • the plug is attached to the tube by gripping protrusions.
  • tube 204 is provided with gripping protrusions 406 in order to increase the contact surface between tube 204 and plug 402 and therefore the force that may be applied to plug 402 when sealing prosthesis 202.
  • plug 402 is ovoid shaped, and/or has a shape such that plug's 402 loose end 408 is larger than the attached end 410 so that, as described in more detail below with respect to Figs. 4A-C , 5 and 7 , plug 402 seals inflatable expandable prosthesis 202 during implantation.
  • a guide wire is introduced (706) via the needle into the space between the rotator cuff tendons and the acromion 302 and coracoid process 304, in an exemplary method.
  • a dilator is placed (708) over the guide wire and extended into the space.
  • a trocar of the dilator is removed (710), leaving a dilator sheath in place.
  • Prosthesis deployment in some methods, means no interposition of tendons and/or other soft tissue between the implanted prosthesis and acromion 302 or coracoid process 304 and/or that during movement of the humerus, the prosthesis remains below acromion 302.
  • Inflation (716) of prosthesis 202 is performed using prosthesis inflation device 200. It should be understood that only a portion of prosthesis inflation device 200 is shown in Fig. 2 , and that exemplary variations are shown in more detail with respect to Figs. 16-17 .
  • Fig. 8 an expandable prosthesis 202 is shown packed for implantation and prior to deployment, in accordance with an exemplary embodiment of the invention. Components of the assembly 800 are enclosed in an external sheath 802 which surrounds at least prosthesis 202, in an exemplary embodiment of the invention.
  • External sheath 802 is adapted to maintain prosthesis 202 in a collapsed condition during placing (712) in order to ease insertion of prosthesis 202 into the implantation space or site through the dilator sheath, in an embodiment of the invention. As described above, once prosthesis 202 is in the implantation space, external sheath 802 is removed, enabling prosthesis 202 to be inflated without hindrance apart from the body parts against which prosthesis 202 is pressing.
  • tube 204 passes through lumen 804 with lumen 804 providing fluid communication between prosthesis implantation and/or inflation device 200 and an inner space defined by the dimensions of prosthesis 202.
  • An attending medical professional performing the implantation procedure holds counterforce ring 506 substantially steady while pulling on tube 204 away from the patient.
  • prosthesis inflation device 200 is adapted to perform the steadying of counterforce ring 506 and/or retraction of tube 204 automatically.
  • a mechanism is provided to prosthesis inflation device 200 which translates rotational movement to a retracting force on tube 204.
  • rotation movement is applied manually.
  • tube 204 continues pulling ("retraction" away from patient) of tube 204 causes a portion of plug 402 to break off, the portion of plug 402 lodging itself in lumen 804 of rigid ring 412 thereby sealing prosthesis 202.
  • the portion of plug 402 becomes partially deformed as it lodges in lumen 804.
  • Prosthesis inflation device 200 now being separated from prosthesis 202 as a result of sealing (718) is withdrawn (720) from the patient and patient is closed.
  • a sponge-like expandable prosthesis device is used and therefore, inflation (716) and inflation related actions may not be carried out, for example prosthesis 100 expands rather than inflates.
  • the implanted prosthesis is secured, using methods known in the art, to soft tissue and/or bone to prevent the prosthesis from being easily displaced by shoulder movement.
  • sutures, clips and/or anchors are used to secure the prosthesis in place.
  • an anchoring expandable prosthesis is used.
  • Simulating a naturally occurring bursa using a prosthesis is an action taken with respect to method 700.
  • simulating is related to inflation (716) in that the prosthesis is inflated to resemble the appropriate size and/or shape and/or characteristics (malleability, compressibility, etc.) of the naturally occurring bursa. Placing the prosthesis at the implantation site and simulating a naturally occurring bursa does not significantly reduce movement of the soft tissues being protected in relation to the other tissues at the implantation site.
  • prosthesis 100 or the elastic prosthesis, described above is implanted by inserting the device directly through a small incision, without a cannula, near the implantation site.
  • At least part of prosthesis 902 (e . g . tubular member 904) is manufactured, in an embodiment of the invention, by dip molding.
  • inflatable tubular member 904 is a seamless balloon made from biocompatible and/or biodegradable synthetic materials such as, but not limited to, PLA, PLGA, PCL, PDO, or any combination and/or families thereof.
  • inflatable tubular member 904 is provided with an outer wall thickness adapted to accommodate at least a minimum level of rigidity necessary to maintain the aligned bone fragments during normal activity. For example, forearm bones are normally subjected to forces ranging from a few hundred grams to several kilograms during normal activity.
  • metacarpal bones are normally subjected to tens of grams to a few hundred grams of force. It should be noted that these ranges are provided as examples only and that depending on patient and/or the bone fragments being aligned, the wall thickness of inflatable tubular member will be adapted to maintain alignment of the bone fragments in spite of the anticipated stress on prosthesis 902 during normal activity and/or rehabilitation of the patient.
  • inflation of prosthesis 902 is performed using a physiologic fluid such as saline, Hartman or Ringer solutions and/or any other biocompatible and/or biodegradable fluid.
  • a physiologic fluid such as saline, Hartman or Ringer solutions and/or any other biocompatible and/or biodegradable fluid.
  • inflation is performed using a biocompatible and/or biodegradable gel.
  • inflation of prosthesis 902 is performed using a gas, for example air and/or carbon dioxide.
  • prosthesis 902 is filled with a cement that hardens and/or seals the open end 906 of prosthesis 902. In some methods, the cement is used provide alignment for the fractured bone segments.
  • prosthesis 902 (and/or other prostheses described herein) is used with a calibration kit which determines the size of the medullar cavity and/or the proper size inflatable tubular member 904 to use with the medullar cavity.
  • the calibration kit is integrated with prosthesis 902.
  • the calibration kit is integrated with prosthesis implantation and/or inflation device 900.
  • a calibration expandable member is first deployed into the medullar cavity to measure the cavity shape and/or size and then upon deployment of prosthesis 902, its shape and/or size is adapted to match the needs of the measured medullar cavity.
  • various sizes of dilators are used in conjunction with the calibration expandable member to assist with determining size.
  • alignment of the bone segments is maintained by the rigidity of prosthesis 902.
  • the rigidity of prosthesis 902 at least partly depends on the internal pressure of prosthesis 902, the internal pressure being at least partly determined by the filler used and/or the percentage of prosthesis 902 that is filled by the filler.
  • an external cast is placed on the area proximal to the fracture.
  • Expandable sponge-like device 1200 optionally contains within its cavities at least one biocompatible and/or biodegradable gelling material, such as methyl cellulose, agarose, poly(ethylene-glycol) (“PEG”) gel and/or PLA gel, that expands when it comes into contact with at least one bodily fluid, for example by absorbing water. Such absorption is partly responsible for an expansion of sponge-like device 1200 into its intended deployed position.
  • biocompatible and/or biodegradable gelling material such as methyl cellulose, agarose, poly(ethylene-glycol) (“PEG”) gel and/or PLA gel
  • device 1200 comprises an inflatable structure.
  • inflatable device 1200 is constructed of at least one biocompatible and/or biodegradable material, such as those described herein.
  • inflatable device 1200 is spherical or cylindrical, having a diameter of 0.5 cm to 5 cm for a sphere or in the long direction (x-axis) and 0.5 cm to 4 cm in the short direction (y-axis) and a height (z-axis) of 0.5 mm to 20 mm.
  • device 1200 is adapted to be inserted deflated into a patient's body through a cannula.
  • the cannula is a 5 mm-7 mm cannula.
  • device 1200 dimensions are adapted for a particular intended use.
  • device 1200 is inflated and/or implanted as described herein with respect to prostheses 100, 202, 902.
  • Device 1200 optionally contains pharmaceutical agents, for example anti-inflammatory drugs and/or antibiotics and/or pro-angiogenesis factors to promote healing, which are eluted into the body.
  • device 1200 is adapted to elute pharmaceutical agents according to a predefined schedule. Adaptation of device 1200 includes construction of device 1200 using materials or combinations of materials which degrade at a predetermined rate, thereby releasing pharmaceutical agents contained therein at a predetermined rate.
  • more than one device 1200 is used for treating inflammation and/or infection:
  • each device is adapted to elute pharmaceutical agents in view of an overall plan incorporating a plurality of devices.
  • an expandable device such as those described herein, is adapted to be used near an articulation to reinforce the articular capsule.
  • the expandable device is introduced in anterior fashion to the shoulder articulation between the articular capsule and the deltoid and pectoralis muscle, in order to prevent recurrent dislocation of the shoulder.
  • the expandable device is introduced in front of the hip joint capsule to prevent anterior dislocation of the hip, especially in cases of congenital dysplasia of hip.
  • the expandable device consists of in inflatable member made of biocompatible and/or biodegradable material.
  • the expandable device has a diameter of 1 cm to 7 cm in the long direction (x-axis) and 1 cm to 5 cm in the short direction (y-axis) with a height (z-axis) of 0.5 mm to 25 mm.
  • the device has a height of 3 mm to 15 mm.
  • Inner section 1302 is manufactured from materials such as polyurethane, ultra high molecular weight polyethylene ("Spectra®”) and/or Kevlar® and/or any reinforced material that can withstand expected pressures on device 1300 as a result of the intended use.
  • inner section 1302 is manufactured from a biocompatible and/or biodegradable substance such as PCL, PGA, PHB, plastarch material, PEEK, zein, PLA, PDO and PLGA, collagen, methyl cellulose, or any combination and/or family members thereof.
  • inner section 1302 and outer section 1304 are operatively connected to separate inflation devices.
  • only one inflation device is needed, for example if outer section 1304 or internal section 1302 is a sponge-like structure.
  • components of device 1300 are removably attached to at least one inflation device such as described elsewhere herein.
  • Fig. 14 is a perspective view, with a cutaway side view of two vertebrae 1402, 1404, of a device 1300 for treating depressed fractures of a vertebra in vivo .
  • device 1300 is adapted to treat osteoporotic fractures of vertebrae.
  • device 1300 is used to deploy a filler, for example cement, to act as a force for restoring the natural shape of the fractured vertebra, thereby relieving pain and restoring at least a modicum of function to the patient.
  • a filler for example cement
  • Prosthesis inflation and/or implantation device 1600 includes a grip 1602 adapted to be grasped in one hand by a medical professional performing the implantation procedure.
  • device 1600 includes a housing 1604 adapted to mount therein a device inflation mechanism, for example a syringe 1606 comprising at least a canister 1608 and a plunger 1610, plunger 1610 adapted to travel within canister 1608 and expel filler out of canister 1608 via an outlet 1612 and into tube 204, described above.
  • syringe 1606 is adapted to hold and/or inject 5-20cc of filler.
  • syringe 1606 is adapted to hold and/or or inject more or less filler depending on the intended application of syringe 1606 and/or needs of the patient.
  • device 1600 includes a compression assembly 1614 adapted to apply force for at least for advancement of plunger 1610 in canister 1608 upon activation of a trigger 1616. Additionally and/or optionally, compression assembly 1614 is adapted to apply force for retraction of plunger 1610.
  • device 1600 is used to direct a prosthesis into an implantation site, as the prosthesis is removably connected to device 1600 via tube 204.
  • FIG. 17 a cutaway side view of an alternate prosthetic inflation and/or implantation device 1700 is shown.
  • device 1700 is adapted to advance and/or retract a canister 1702 portion of a syringe 1704 with a plunger 1706 portion remaining relatively fixed in relation to device 1700.
  • Plunger 1706 portion is provided with counterforce, as canister 1702 portion is moved towards a proximal end 1708 of device 1700, by a backstop 1710.
  • Backstop 1710 in some examples, is fixed to device 1700. In an example, the placement of the backstop is according to a predetermined level of desired inflation of the prosthesis.
  • Safety 1712 is comprised of a ball 1714 and a spring 1716 whereby ball 1714 and backstop 1710 are adapted to be counterparts such that ball 1714 releasably fits into a groove on backstop 1710 shaped to receive ball 1714.

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • On-Site Construction Work That Accompanies The Preparation And Application Of Concrete (AREA)
  • Materials For Medical Uses (AREA)

Claims (14)

  1. System zum Abdichten einer inflatierbaren Prothese, umfassend:
    eine inflatierbare Prothese (202, 902),
    eine Protheseninflatiervorrichtung (200; 900),
    eine Röhre (204) mit einem ersten Ende und einem zweiten Ende, wobei die Röhre (204) in der Nähe des ersten Endes mit der Prothese (202; 902) und am zweiten Ende mit der Protheseninflatiervorrichtung (200; 900) wirkverbunden ist, und
    einen starren Ring (412), der an der Prothese (202; 902) angebracht ist und zwischen der Protheseninflatiervorrichtung (200; 900) und dem ersten Ende der Röhre (204) verschiebbar um die Röhre (204) herum angebracht ist, dadurch gekennzeichnet, dass das System ferner einen am ersten Ende der Röhre (204) an der Röhre (204) angebrachten Stopfen (402) umfasst,
    wobei Ziehen der Röhre zu der Protheseninflatiervorrichtung (200; 900) hin veranlasst, dass sich der Stopfen im starren Ring (412) festklemmt, wodurch die Prothese (202; 902) mit dem Stopfen (402) abgedichtet wird.
  2. System nach Anspruch 1, wobei der Stopfen (402) über Greifvorsprünge (406) an der Röhre (204) angebracht ist.
  3. System nach Anspruch 1, umfassend einen Gegenkraftring (506), der geeignet ist, den starren Ring (412) während des Trennens der Protheseninflatiervorrichtung (200; 900) von der Prothese (202; 902) mit Gegenkraft zu beaufschlagen.
  4. System nach Anspruch 3, wobei der starre Ring (412) durch Ziehen der Röhre (204) zu der Protheseninflatiervorrichtung (200; 900) hin mit dem Gegenkraftring (506) in Kontakt gebracht wird.
  5. System nach Anspruch 3 oder Anspruch 4, wobei der Gegenkraftring (506) aus einem biokompatiblen Material konstruiert ist.
  6. System nach Anspruch 5, wobei das biokompatible Material ungefähr mindestens so hart wie der starre Ring (412) ist.
  7. System nach Anspruch 1, umfassend eine äußere Hülle (802), die die Prothese (202; 902) umschließt.
  8. System nach Anspruch 1, wobei der starre Ring (412) ein Lumen definiert und das Abdichten der Prothese (202; 902) mit dem Stopfen (402) umfasst, dass sich der Stopfen im Lumen festklemmt.
  9. System nach Anspruch 1, wobei die Röhre (204) geeignet ist, den Durchgang einer zum Füllen der Prothese (202; 902) verwendeten Substanz durch sie zu gestatten.
  10. System nach Anspruch 9, wobei die Röhre geeignet ist, den Durchgang der zum Füllen der Prothese verwendeten Substanz durch sie zu gestatten, indem mindestens eine Öffnung (404) in der Röhre (204) vorgesehen ist.
  11. System nach Anspruch 1, wobei der Stopfen (402) an dem der Prothese (202; 902) am nächsten liegenden Ende der Röhre (204) angebracht ist.
  12. System nach Anspruch 1, wobei die Röhre (204) mit Greifvorsprüngen (406) versehen ist, um die Kontaktfläche zwischen der Röhre (204) und dem Stopfen (402) zu vergrößern.
  13. System nach Anspruch 1, wobei mindestens die Röhre (204) und/oder der Stopfen (402) und/oder der starre Ring (412) aus biologisch abbaubaren und/oder biokompatiblen Materialien hergestellt sind.
  14. System nach Anspruch 1, wobei der Durchmesser des Stopfens (402) größer ist als der Innendurchmesser des starren Rings (412).
EP16177165.4A 2007-03-15 2008-03-13 System zum versiegeln einer aifblasbaren prothese Active EP3111869B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91805107P 2007-03-15 2007-03-15
EP08719972.5A EP2124831B1 (de) 2007-03-15 2008-03-13 Prothesenvorrichtungen

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EP3111869A1 EP3111869A1 (de) 2017-01-04
EP3111869B1 true EP3111869B1 (de) 2017-09-20

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EP16177165.4A Active EP3111869B1 (de) 2007-03-15 2008-03-13 System zum versiegeln einer aifblasbaren prothese

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IL200939A (en) 2014-09-30
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CN101854886B (zh) 2014-12-24
ES2645409T3 (es) 2017-12-05
EP2124831B1 (de) 2016-07-06
ES2593085T3 (es) 2016-12-05
US20140296987A1 (en) 2014-10-02
AU2008224435A1 (en) 2008-09-18
US20210338441A1 (en) 2021-11-04
JP5271288B2 (ja) 2013-08-21
CN104473704B (zh) 2017-06-16
CA2680812A1 (en) 2008-09-18
US8753390B2 (en) 2014-06-17
US11033398B2 (en) 2021-06-15
AU2008224435B2 (en) 2014-01-09
PL2124831T3 (pl) 2017-03-31
EP2124831A2 (de) 2009-12-02
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CA2680812C (en) 2017-01-24
WO2008111073A3 (en) 2010-02-18
JP6030993B2 (ja) 2016-11-24
CN101854886A (zh) 2010-10-06
US20100023127A1 (en) 2010-01-28
EP3111869A1 (de) 2017-01-04
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IL200939A0 (en) 2010-05-17
CN104473704A (zh) 2015-04-01

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